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SE8204064L - Tissue adhesive AND SET FOR ITS PREPARATION - Google Patents

Tissue adhesive AND SET FOR ITS PREPARATION

Info

Publication number
SE8204064L
SE8204064L SE8204064A SE8204064A SE8204064L SE 8204064 L SE8204064 L SE 8204064L SE 8204064 A SE8204064 A SE 8204064A SE 8204064 A SE8204064 A SE 8204064A SE 8204064 L SE8204064 L SE 8204064L
Authority
SE
Sweden
Prior art keywords
fibrinogen
factor xiii
antibiotic
tissue adhesive
preparation
Prior art date
Application number
SE8204064A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE459848B (en
SE8204064D0 (en
Inventor
H Redl
T Seelich
Y Linnau
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of SE8204064D0 publication Critical patent/SE8204064D0/en
Publication of SE8204064L publication Critical patent/SE8204064L/en
Publication of SE459848B publication Critical patent/SE459848B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A tissue adhesive based on human or animal proteins contains factor XIII, fibrinogen and an antibiotic. In order to achieve a high straining capacity of the adherences and a retarded antimicrobial efficacy, the ratio of factor XIII to fibrinogen, expressed in units of factor XIII per gram of fibrinogen, amounts to at least 500. The antibiotic is chosen among amino-glucosides, beta- lactams, polypeptides or tetracyclines. In a method of producing the tissue adhesive the concentration ratio of factor XIII to fibrinogen is adjusted in a fibrinogen-containing blood plasma fraction by the addition of factor XIII. The antibiotic is added either before deepfreezing or lyophilization of the resulting preparation, or after thawing or reconstitution of the same.
SE8204064A 1981-07-28 1982-07-01 TEXTILE FILM CONTAINING FACTOR XIII, THE FIBRINOGEN AND ANTIBIOTIC, AND SUCH BEFORE ITS PREPARATION SE459848B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0333781A AT369990B (en) 1981-07-28 1981-07-28 METHOD FOR PRODUCING A TISSUE ADHESIVE

Publications (3)

Publication Number Publication Date
SE8204064D0 SE8204064D0 (en) 1982-07-01
SE8204064L true SE8204064L (en) 1983-01-29
SE459848B SE459848B (en) 1989-08-14

Family

ID=3548998

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204064A SE459848B (en) 1981-07-28 1982-07-01 TEXTILE FILM CONTAINING FACTOR XIII, THE FIBRINOGEN AND ANTIBIOTIC, AND SUCH BEFORE ITS PREPARATION

Country Status (14)

Country Link
JP (1) JPH0696039B2 (en)
AR (1) AR227252A1 (en)
AT (1) AT369990B (en)
BE (1) BE893851A (en)
CA (1) CA1168982A (en)
CH (1) CH659187B (en)
DE (1) DE3225102A1 (en)
DK (1) DK157977C (en)
ES (1) ES8306023A1 (en)
FR (1) FR2510408B1 (en)
GB (1) GB2102811B (en)
IT (1) IT1157313B (en)
NL (1) NL192665C (en)
SE (1) SE459848B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102628B2 (en) * 1984-03-27 1994-12-14 イムノ・アクチエンゲゼルシャフト Tissue adhesive manufacturing method
JPS6185304A (en) * 1984-10-01 1986-04-30 Green Cross Corp:The Auxiliary for dental treatment
DE3622642A1 (en) * 1986-07-05 1988-01-14 Behringwerke Ag ONE-COMPONENT TISSUE ADHESIVE AND METHOD FOR THE PRODUCTION THEREOF
AT397203B (en) * 1988-05-31 1994-02-25 Immuno Ag FABRIC ADHESIVE
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
NZ229385A (en) * 1989-06-01 1992-02-25 Life Technologies Inc Treatment of processed fish product (surimi) with alpha-2-macroglobulin to neutralise alkaline proteases in the fish
IT1243180B (en) * 1990-07-31 1994-05-24 Nunzio Rapisarda USE OF PHOSPHOMYCIN AND ITS SALTS AS A TOPICAL CICATRIZING AGENT
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US7189410B1 (en) 1990-11-27 2007-03-13 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
ATE151295T1 (en) * 1992-07-18 1997-04-15 Omrix Biopharm Sa TWO-COMPONENT FIBRIN ADHESIVE TO IMPROVE IN-VITRO FERTILIZATION
US5330974A (en) * 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
EP0696201B2 (en) † 1993-03-12 2012-09-19 The American National Red Cross Supplemented tissue sealants, methods of their production and use
JPH08512215A (en) * 1993-03-30 1996-12-24 オパーバス・ホールディング・ビー・ブイ Two-component fibrin glue
DE19521324C1 (en) * 1995-06-12 1996-10-31 Immuno Ag Tissue adhesive and use thereof as a hemostatic
DE19617369A1 (en) * 1996-04-30 1997-11-06 Immuno Ag Storage-stable fibrinogen preparations
AT406120B (en) 1997-08-28 2000-02-25 Immuno Ag TISSUE ADHESIVE
AT407484B (en) 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag MEDICINES FOR PROMOTING Wound Healing
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
HK1047754B (en) 1999-12-23 2009-11-20 Csl Limited Separation of fibrinogen from plasma proteases
US6506365B1 (en) 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
IL144446A0 (en) * 2001-07-19 2002-05-23 Prochon Biotech Ltd Plasma protein matrices and methods for their preparation
EP1545636B1 (en) 2002-09-10 2015-01-07 The American National Red Cross Hemostatic dressing
WO2006021584A2 (en) 2004-08-27 2006-03-02 Novo Nordisk Health Care Ag Purification of factor xiii polypeptides from biological materials
US8461302B2 (en) 2004-11-23 2013-06-11 Zymogenetics, Inc. Purification of recombinant human factor XIII
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20080033333A1 (en) 2006-08-04 2008-02-07 Macphee Martin Solid dressing for treating wounded tissue
US20090075891A1 (en) 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
MX2024008243A (en) 2021-12-30 2024-09-04 Baxter Int Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT359652B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
AT359653B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
WO1981000516A1 (en) * 1979-08-31 1981-03-05 Merck Patent Gmbh Gel containing fibrine and antibiotic for treating infected bones and preparation process thereof

Also Published As

Publication number Publication date
FR2510408A1 (en) 1983-02-04
AT369990B (en) 1983-02-25
DK157977C (en) 1990-08-13
NL8202982A (en) 1983-02-16
NL192665B (en) 1997-08-01
JPH0696039B2 (en) 1994-11-30
GB2102811B (en) 1985-01-30
SE459848B (en) 1989-08-14
IT1157313B (en) 1987-02-11
DE3225102C2 (en) 1990-05-31
SE8204064D0 (en) 1982-07-01
CH659187B (en) 1987-01-15
GB2102811A (en) 1983-02-09
AR227252A1 (en) 1982-09-30
ES514441A0 (en) 1983-05-01
ATA333781A (en) 1982-07-15
IT8222595A0 (en) 1982-07-27
FR2510408B1 (en) 1987-02-27
NL192665C (en) 1997-12-02
DK300682A (en) 1983-01-29
CA1168982A (en) 1984-06-12
DE3225102A1 (en) 1983-02-17
BE893851A (en) 1982-11-16
ES8306023A1 (en) 1983-05-01
JPS5826821A (en) 1983-02-17
DK157977B (en) 1990-03-12

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