SE8202023L - Nya foreningar, forfaranden for framstellning och farmaceutiska beredningar for sadana foreningar - Google Patents
Nya foreningar, forfaranden for framstellning och farmaceutiska beredningar for sadana foreningarInfo
- Publication number
- SE8202023L SE8202023L SE8202023A SE8202023A SE8202023L SE 8202023 L SE8202023 L SE 8202023L SE 8202023 A SE8202023 A SE 8202023A SE 8202023 A SE8202023 A SE 8202023A SE 8202023 L SE8202023 L SE 8202023L
- Authority
- SE
- Sweden
- Prior art keywords
- group
- carbon atoms
- alkyl group
- hydrogen
- chem
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- -1 2,6-dimethylphenyl Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 125000004208 3-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(*)=C1[H] 0.000 abstract 1
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cosmetics (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8202023A SE446335B (sv) | 1982-03-30 | 1982-03-30 | Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin |
| NO831040A NO164024C (no) | 1982-03-30 | 1983-03-23 | Analogifremgangsmaate for fremstilling av terapeutisk aktive enantiomerer av substituerte fenylazacykloalkaner. |
| AU12845/83A AU564287B2 (en) | 1982-03-30 | 1983-03-25 | N-propyl,3-(substituted phenyl)piperidine |
| DE8383850084T DE3381885D1 (de) | 1982-03-30 | 1983-03-28 | Piperidinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
| EP83850084A EP0097628B1 (en) | 1982-03-30 | 1983-03-28 | Piperidine derivatives, processes for their preparation and pharmaceutical preparation containing them |
| AT83850084T ATE56705T1 (de) | 1982-03-30 | 1983-03-28 | Piperidinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
| IE685/83A IE55261B1 (en) | 1982-03-30 | 1983-03-28 | Enantiomers of substituted phenylpiperidines |
| DK143483A DK162214C (da) | 1982-03-30 | 1983-03-29 | Analogifremgangsmaade til fremstilling af en ren enantiomer af 3-fenyl-n-n-propylpiperidinderivater |
| FI831068A FI81088C (sv) | 1982-03-30 | 1983-03-29 | Förfarande för framställning av farmakologiskt aktiva, rena enantiomer er av N-n-propyl-3-(3-hydroxifenyl)-piperidinderivater |
| HU831073A HU191290B (en) | 1982-03-30 | 1983-03-29 | Process for preparing the enantiomers of substituted phenyl-piperidine derivatives |
| ES521080A ES8405372A1 (es) | 1982-03-30 | 1983-03-29 | Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido. |
| CA000424804A CA1202307A (en) | 1982-03-30 | 1983-03-29 | (-)-3-(-hydroxyphenul)-n-n-propylpiperidine and derivatives thereof |
| GB08308657A GB2117771B (en) | 1982-03-30 | 1983-03-29 | Enantiomers of substituted phenylazacycloalkanes |
| GR70924A GR79244B (sv) | 1982-03-30 | 1983-03-29 | |
| JP58051781A JPS58177971A (ja) | 1982-03-30 | 1983-03-29 | 置換フエニルアザシクロアルカン化合物およびド−パミンレセプタ−作働剤 |
| PT76481A PT76481B (en) | 1982-03-30 | 1983-03-30 | Process for preparing new enantiomers of substituted phenylazacycloalkanes and of pharmaceutical compositions |
| DD83249351A DD209621A5 (de) | 1982-03-30 | 1983-03-30 | Verfahren zur herstellung von enantiomeren substituierter phenylazacycloalkane |
| ES530186A ES530186A0 (es) | 1982-03-30 | 1984-03-01 | Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido |
| US06/656,616 US4719219A (en) | 1982-03-30 | 1984-10-01 | Phenyl-azacycloalkanes and use thereof in treatment of central nervous system disorders |
| ES539031A ES539031A0 (es) | 1982-03-30 | 1984-12-24 | Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido |
| US07/126,916 US4937346A (en) | 1979-12-05 | 1987-11-30 | Phenyl-azacykloalkanes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8202023A SE446335B (sv) | 1982-03-30 | 1982-03-30 | Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8202023L true SE8202023L (sv) | 1983-10-01 |
| SE446335B SE446335B (sv) | 1986-09-01 |
Family
ID=20346417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8202023A SE446335B (sv) | 1979-12-05 | 1982-03-30 | Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0097628B1 (sv) |
| JP (1) | JPS58177971A (sv) |
| AT (1) | ATE56705T1 (sv) |
| AU (1) | AU564287B2 (sv) |
| CA (1) | CA1202307A (sv) |
| DD (1) | DD209621A5 (sv) |
| DE (1) | DE3381885D1 (sv) |
| DK (1) | DK162214C (sv) |
| ES (3) | ES8405372A1 (sv) |
| FI (1) | FI81088C (sv) |
| GB (1) | GB2117771B (sv) |
| GR (1) | GR79244B (sv) |
| HU (1) | HU191290B (sv) |
| IE (1) | IE55261B1 (sv) |
| NO (1) | NO164024C (sv) |
| PT (1) | PT76481B (sv) |
| SE (1) | SE446335B (sv) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8305362D0 (sv) * | 1983-09-30 | 1983-09-30 | Astra Laekemedel Ab | Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| JP2011057619A (ja) * | 2009-09-10 | 2011-03-24 | Tokai Univ | 光学活性アミン化合物の製造方法、並びに、ジアステレオマー塩及びその製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3070247D1 (en) * | 1979-12-05 | 1985-04-04 | Astra Laekemedel Ab | New phenyl-azacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds |
-
1982
- 1982-03-30 SE SE8202023A patent/SE446335B/sv unknown
-
1983
- 1983-03-23 NO NO831040A patent/NO164024C/no unknown
- 1983-03-25 AU AU12845/83A patent/AU564287B2/en not_active Ceased
- 1983-03-28 AT AT83850084T patent/ATE56705T1/de not_active IP Right Cessation
- 1983-03-28 EP EP83850084A patent/EP0097628B1/en not_active Expired - Lifetime
- 1983-03-28 IE IE685/83A patent/IE55261B1/en not_active IP Right Cessation
- 1983-03-28 DE DE8383850084T patent/DE3381885D1/de not_active Expired - Fee Related
- 1983-03-29 JP JP58051781A patent/JPS58177971A/ja active Granted
- 1983-03-29 GR GR70924A patent/GR79244B/el unknown
- 1983-03-29 ES ES521080A patent/ES8405372A1/es not_active Expired
- 1983-03-29 GB GB08308657A patent/GB2117771B/en not_active Expired
- 1983-03-29 DK DK143483A patent/DK162214C/da not_active IP Right Cessation
- 1983-03-29 FI FI831068A patent/FI81088C/sv not_active IP Right Cessation
- 1983-03-29 HU HU831073A patent/HU191290B/hu not_active IP Right Cessation
- 1983-03-29 CA CA000424804A patent/CA1202307A/en not_active Expired
- 1983-03-30 PT PT76481A patent/PT76481B/pt not_active IP Right Cessation
- 1983-03-30 DD DD83249351A patent/DD209621A5/de not_active IP Right Cessation
-
1984
- 1984-03-01 ES ES530186A patent/ES530186A0/es active Granted
- 1984-12-24 ES ES539031A patent/ES539031A0/es active Granted
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