SE8102161L - "3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic - Google Patents
"3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoicInfo
- Publication number
- SE8102161L SE8102161L SE8102161A SE8102161A SE8102161L SE 8102161 L SE8102161 L SE 8102161L SE 8102161 A SE8102161 A SE 8102161A SE 8102161 A SE8102161 A SE 8102161A SE 8102161 L SE8102161 L SE 8102161L
- Authority
- SE
- Sweden
- Prior art keywords
- tetramethyl
- hexadecapentaenoic
- keratinisation
- salts
- preparation
- Prior art date
Links
- UUBHZHZSIKRVIV-KCXSXWJSSA-N (2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,4,6,10,14-pentaenoic acid Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\C=C\C(\C)=C\C(O)=O UUBHZHZSIKRVIV-KCXSXWJSSA-N 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic acid and its salts are anticancer agents and therapeutic agents for treatment of skin diseases with keratinisation. The preparation of the ethyl ester is described.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4455880A JPS56140949A (en) | 1980-04-07 | 1980-04-07 | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid |
| JP10442080A JPS5731615A (en) | 1980-07-31 | 1980-07-31 | Remedy for skin disease with keratinization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8102161L true SE8102161L (en) | 1981-10-08 |
| SE447243B SE447243B (en) | 1986-11-03 |
Family
ID=26384501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8102161A SE447243B (en) | 1980-04-07 | 1981-04-03 | 3,7,11,15-TETRAMETHYL-2,4,6,10,14-HEXADECAPENTAIC ACID AND PHARMACEUTICAL COMPOSITION CONTAINING THIS |
Country Status (11)
| Country | Link |
|---|---|
| AU (1) | AU537402B2 (en) |
| CA (1) | CA1179370A (en) |
| CH (1) | CH646682A5 (en) |
| DE (1) | DE3113149A1 (en) |
| DK (1) | DK158457C (en) |
| ES (2) | ES501124A0 (en) |
| FR (1) | FR2479807A1 (en) |
| GB (1) | GB2073750B (en) |
| IT (1) | IT1194141B (en) |
| NL (1) | NL191744C (en) |
| SE (1) | SE447243B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56140949A (en) * | 1980-04-07 | 1981-11-04 | Eisai Co Ltd | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid |
| DE3163920D1 (en) * | 1980-12-24 | 1984-07-05 | Eisai Co Ltd | Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases |
| JPS57106638A (en) * | 1980-12-24 | 1982-07-02 | Eisai Co Ltd | Conjugated polyprenylcarboxylic acid and its derivative |
| JPS58164508A (en) * | 1982-03-26 | 1983-09-29 | Eisai Co Ltd | Composition for external use containing isoprenyl-carboxylic acid |
| JPS5973516A (en) * | 1982-10-21 | 1984-04-25 | Eisai Co Ltd | Antiphlogistic agent |
| JPS6160612A (en) * | 1984-08-31 | 1986-03-28 | Eisai Co Ltd | Carcinostatic intensifier |
| IL107587A (en) * | 1993-11-12 | 1998-08-16 | Univ Ramot | Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation |
| WO2001080854A1 (en) | 2000-04-24 | 2001-11-01 | Nikken Chemicals Co., Ltd. | Activators for peroxisome proliferator-activated receptor |
| CN116041172B (en) * | 2023-02-01 | 2024-08-02 | 宝鸡文理学院 | A preparation method of nervonic acid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2171497A5 (en) * | 1972-02-02 | 1973-09-21 | Rhone Poulenc Sa | 1,5-dimethyl-1,5-hexadienylidene sulphone derivs - - intermediates for terpenes |
| JPS52131507A (en) * | 1976-04-24 | 1977-11-04 | Sankyo Co Ltd | Polyprenyl derivatives |
-
1981
- 1981-04-01 NL NL8101630A patent/NL191744C/en not_active IP Right Cessation
- 1981-04-01 GB GB8110160A patent/GB2073750B/en not_active Expired
- 1981-04-01 DE DE19813113149 patent/DE3113149A1/en active Granted
- 1981-04-03 SE SE8102161A patent/SE447243B/en not_active IP Right Cessation
- 1981-04-06 CA CA000374715A patent/CA1179370A/en not_active Expired
- 1981-04-06 CH CH231781A patent/CH646682A5/en not_active IP Right Cessation
- 1981-04-06 DK DK155081A patent/DK158457C/en not_active IP Right Cessation
- 1981-04-06 ES ES501124A patent/ES501124A0/en active Granted
- 1981-04-06 FR FR8106874A patent/FR2479807A1/en active Granted
- 1981-04-07 AU AU69159/81A patent/AU537402B2/en not_active Ceased
- 1981-04-07 IT IT20967/81A patent/IT1194141B/en active
-
1982
- 1982-02-25 ES ES509913A patent/ES509913A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| SE447243B (en) | 1986-11-03 |
| NL8101630A (en) | 1981-11-02 |
| AU6915981A (en) | 1981-10-15 |
| ES8304058A1 (en) | 1983-02-16 |
| ES8205190A1 (en) | 1982-06-01 |
| DE3113149C2 (en) | 1988-11-10 |
| IT8120967A0 (en) | 1981-04-07 |
| DK155081A (en) | 1981-10-08 |
| DK158457B (en) | 1990-05-21 |
| GB2073750A (en) | 1981-10-21 |
| GB2073750B (en) | 1984-02-22 |
| ES509913A0 (en) | 1983-02-16 |
| NL191744C (en) | 1996-06-04 |
| ES501124A0 (en) | 1982-06-01 |
| DK158457C (en) | 1990-10-08 |
| IT1194141B (en) | 1988-09-14 |
| AU537402B2 (en) | 1984-06-21 |
| CH646682A5 (en) | 1984-12-14 |
| FR2479807A1 (en) | 1981-10-09 |
| NL191744B (en) | 1996-02-01 |
| CA1179370A (en) | 1984-12-11 |
| FR2479807B1 (en) | 1984-07-20 |
| DE3113149A1 (en) | 1982-01-28 |
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| NAL | Patent in force |
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