SE8101311L - Heterocykliska foreningar - Google Patents

Heterocykliska foreningar

Info

Publication number: SE8101311L
Authority: SE; Sweden
Prior art keywords: associations; heterocyclic; bioprecursors; hydrates; antagonists
Prior art date: 1980-02-28

Application number

SE8101311A

Other languages

English (en)

Other versions

SE448233B (sv

Inventor

J W Clitherow

J Bradshaw

J W M Mackinnon

D B Judd

D E Bays

R Hayes

A Pearce

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-28

Filing date

1981-02-27

Publication date

1981-08-29

1981-02-27 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1981-08-29 Publication of SE8101311L publication Critical patent/SE8101311L/sv

1987-02-02 Publication of SE448233B publication Critical patent/SE448233B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Indole Compounds (AREA)

SE8101311A 1980-02-28 1981-02-27 1,2,4-triazolderivat, forfarande for framstellning derav och farmaceutisk komposition SE448233B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8006806		1980-02-28

Publications (2)

Publication Number	Publication Date
SE8101311L true SE8101311L (sv)	1981-08-29
SE448233B SE448233B (sv)	1987-02-02

Family

ID=10511754

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8101311A SE448233B (sv)	1980-02-28	1981-02-27	1,2,4-triazolderivat, forfarande for framstellning derav och farmaceutisk komposition

Country Status (26)

Country	Link
US (1)	US4670448A (sv)
JP (2)	JPS56147777A (sv)
KR (3)	KR850000668B1 (sv)
AT (2)	AT380240B (sv)
AU (1)	AU544357B2 (sv)
BE (1)	BE887730A (sv)
CA (1)	CA1158649A (sv)
CH (1)	CH655104A5 (sv)
CY (1)	CY1335A (sv)
DE (1)	DE3107628A1 (sv)
DK (1)	DK90681A (sv)
ES (4)	ES8205208A1 (sv)
FI (1)	FI76076C (sv)
FR (1)	FR2477150A1 (sv)
GB (1)	GB2075007B (sv)
HK (1)	HK69186A (sv)
IE (1)	IE50987B1 (sv)
IL (1)	IL62229A (sv)
IT (1)	IT1209846B (sv)
KE (1)	KE3629A (sv)
MY (1)	MY8500428A (sv)
NL (2)	NL186812C (sv)
NO (1)	NO810681L (sv)
NZ (1)	NZ196365A (sv)
SE (1)	SE448233B (sv)
ZA (1)	ZA811331B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57169452A (en) *	1981-04-14	1982-10-19	Teikoku Hormone Mfg Co Ltd	Novel phenoxyalkylamide derivative
AU8480982A (en) *	1981-06-11	1983-01-13	Glaxo Group Limited	1,2,4-triazole derivatives with histamine h2-blocking activity
PT76280A (en) *	1982-02-24	1983-03-01	Glaxo Group Ltd	Process for preparing heterocyclic derivatives
CA1189508A (en) *	1982-02-25	1985-06-25	Roger Hayes	Heterocyclic derivatives as histamine h.sub.2- antagonists
GB8417194D0 (en) *	1984-07-05	1984-08-08	Boots Co Plc	Therapeutic agents
GB8628475D0 (en) *	1986-11-28	1987-01-07	Glaxo Group Ltd	Medicaments
GB8805268D0 (en) *	1988-03-04	1988-04-07	Glaxo Group Ltd	Medicaments
JP3328082B2 (ja) *	1994-12-13	2002-09-24	日本カーバイド工業株式会社	Ｎ−グアニジノチオ尿素塩及び３−アミノ−５−メルカプト−１，２，４−トリアゾールの製造方法
EP1223932A4 (en) *	1999-10-01	2003-01-15	Smithkline Beecham Corp	COMPOUNDS AND METHODS
JP4564786B2 (ja) *	2004-06-07	2010-10-20	株式会社日本ファインケム	１−置換―１―アミノグアニジン又はその塩、及びこれらの製造方法
WO2022034121A1 (en)	2020-08-11	2022-02-17	Université De Strasbourg	H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1419994A (en) *	1973-05-03	1976-01-07	Smith Kline French Lab	Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
DE2835695A1 (de) *	1977-08-29	1979-03-15	Yamanouchi Pharma Co Ltd	Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) *	1978-04-26	1983-05-13	Glaxo Group Ltd	Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
GB2023133B (en) *	1978-04-26	1982-09-08	Glaxo Group Ltd	Heterocyclic derivatives
FI68395C (fi) *	1979-03-02	1985-09-10	Glaxo Group Ltd	Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar

1981
- 1981-02-26 CH CH1288/81A patent/CH655104A5/fr not_active IP Right Cessation
- 1981-02-26 FR FR8103847A patent/FR2477150A1/fr active Granted
- 1981-02-27 NL NLAANVRAGE8100979,A patent/NL186812C/xx not_active IP Right Cessation
- 1981-02-27 DK DK90681A patent/DK90681A/da not_active Application Discontinuation
- 1981-02-27 NZ NZ196365A patent/NZ196365A/en unknown
- 1981-02-27 ZA ZA00811331A patent/ZA811331B/xx unknown
- 1981-02-27 CA CA000371889A patent/CA1158649A/en not_active Expired
- 1981-02-27 AT AT0093981A patent/AT380240B/de not_active IP Right Cessation
- 1981-02-27 IL IL62229A patent/IL62229A/xx unknown
- 1981-02-27 FI FI810619A patent/FI76076C/sv not_active IP Right Cessation
- 1981-02-27 SE SE8101311A patent/SE448233B/sv not_active IP Right Cessation
- 1981-02-27 CY CY133581A patent/CY1335A/en unknown
- 1981-02-27 AU AU67933/81A patent/AU544357B2/en not_active Ceased
- 1981-02-27 NO NO810681A patent/NO810681L/no unknown
- 1981-02-27 GB GB8106314A patent/GB2075007B/en not_active Expired
- 1981-02-27 BE BE0/203963A patent/BE887730A/fr unknown
- 1981-02-27 IE IE431/81A patent/IE50987B1/en unknown
- 1981-02-27 DE DE19813107628 patent/DE3107628A1/de active Granted
- 1981-02-27 IT IT8147905A patent/IT1209846B/it active
- 1981-02-27 ES ES499931A patent/ES8205208A1/es not_active Expired
- 1981-02-28 KR KR1019810000669A patent/KR850000668B1/ko not_active Expired
- 1981-02-28 JP JP2929381A patent/JPS56147777A/ja active Granted
1982
- 1982-02-16 ES ES509669A patent/ES8304954A1/es not_active Expired
- 1982-12-16 ES ES518305A patent/ES8405775A1/es not_active Expired
1983
- 1983-02-10 US US06/465,616 patent/US4670448A/en not_active Expired - Fee Related
1984
- 1984-03-16 ES ES530741A patent/ES8506292A1/es not_active Expired
- 1984-05-08 AT AT0151084A patent/AT387774B/de not_active IP Right Cessation
- 1984-08-18 KR KR1019840004976A patent/KR850000682B1/ko not_active Expired
- 1984-08-20 KR KR1019840004977A patent/KR850000676B1/ko not_active Expired
1985
- 1985-12-30 MY MY428/85A patent/MY8500428A/xx unknown
1986
- 1986-04-16 KE KE3629A patent/KE3629A/xx unknown
- 1986-09-18 HK HK691/86A patent/HK69186A/xx unknown
1988
- 1988-02-29 JP JP63047352A patent/JPS6452763A/ja active Pending
- 1988-09-09 NL NL8802221A patent/NL8802221A/nl not_active Application Discontinuation

Also Published As

Publication number	Publication date
IT8147905A0 (it)	1981-02-27
JPS56147777A (en)	1981-11-16
DE3107628C2 (sv)	1991-03-14
JPH0338269B2 (sv)	1991-06-10
KR850002010A (ko)	1985-04-10
FI76076C (sv)	1988-09-09
GB2075007B (en)	1983-07-13
FI810619L (fi)	1981-08-29
KR850002011A (ko)	1985-04-10
NO810681L (no)	1981-08-31
FR2477150A1 (fr)	1981-09-04
DE3107628A1 (de)	1982-04-01
KR850000676B1 (ko)	1985-05-10
ATA151084A (de)	1988-08-15
ES518305A0 (es)	1984-06-16
CH655104A5 (fr)	1986-03-27
ES499931A0 (es)	1982-06-01
ES530741A0 (es)	1985-07-01
AU6793381A (en)	1981-09-03
KR850000668B1 (ko)	1985-05-09
NL8802221A (nl)	1989-01-02
IE810431L (en)	1981-08-28
NL8100979A (nl)	1981-10-01
JPS6452763A (en)	1989-02-28
IE50987B1 (en)	1986-09-03
GB2075007A (en)	1981-11-11
IL62229A0 (en)	1981-03-31
FR2477150B1 (sv)	1984-03-16
DK90681A (da)	1981-08-29
ZA811331B (en)	1982-10-27
FI76076B (fi)	1988-05-31
CA1158649A (en)	1983-12-13
ES509669A0 (es)	1983-03-16
KR830005164A (ko)	1983-08-03
HK69186A (en)	1986-09-26
SE448233B (sv)	1987-02-02
NZ196365A (en)	1984-07-31
BE887730A (fr)	1981-08-27
ES8304954A1 (es)	1983-03-16
KR850000682B1 (ko)	1985-05-14
AT380240B (de)	1986-04-25
IL62229A (en)	1987-10-30
CY1335A (en)	1986-10-24
ES8205208A1 (es)	1982-06-01
ES8405775A1 (es)	1984-06-16
NL186812B (nl)	1990-10-01
ATA93981A (de)	1985-09-15
IT1209846B (it)	1989-08-30
KE3629A (en)	1986-05-16
NL186812C (nl)	1991-03-01
ES8506292A1 (es)	1985-07-01
MY8500428A (en)	1985-12-31
US4670448A (en)	1987-06-02
AT387774B (de)	1989-03-10
AU544357B2 (en)	1985-05-23

Publication	Publication Date	Title
KR870700619A (ko)	1987-12-30	피콜린 유도체 및 그 제조방법 및 그 용도 및 그를 포함한 약제
AR222481A1 (es)	1981-05-29	Procedimiento para obtener derivados de 1-(omega-alcanoiltio o omega-mercaptoalconoil)3,4-deshidroprolina
SE8302693L (sv)	1983-11-13	Heterocykliska foreningar
IT7827849A0 (it)	1978-09-19	Sintesi di 2-cheto-1,4-diazacicloalcani.
NL7803312A (nl)	1978-10-03	Nieuwe 5-(4-(diarylmethyl)-1-piperazinylalkyl)- benzimidazoolderivaten, alsmede therapeutische preparaten, die dergelijke derivaten bevatten.
SE8600174D0 (sv)	1986-01-15	Nytt forfarande for framstellning av n-(2-pyrimidinyl)-piperazinylalkylazaspiroalkandioner
SE8101311L (sv)	1981-08-29	Heterocykliska foreningar
FI803461L (fi)	1981-05-08	Framstaellning och anvaendning av aemnen som reglerar tillvaexten hos vaexter
DK0490816T3 (da)	1997-09-22	Fluorforbindelser som aromatase-inhibitorer.
FI863565A0 (fi)	1986-09-04	Foerfarande foer framstaellning av nya pyrrobenzimidazoler, pyrrolbenzoxazoler och pyrrolbenztiazoler.
DK162682A (da)	1982-10-10	Oxindolderivater,deres fremstilling og anvendelse
AR227542A1 (es)	1982-11-15	Procedimiento para preparar derivados de 4-(4-amino-6,7-dimetoxi-quinazolin-2-il)-1-(2,4-dioxo-2,2,3,4-tetrahidro-pirimidin-6-il)-piperazina
IT8219282A0 (it)	1982-01-25	Ricerca tabellare di funzioni nonlineari utilizzando memorie di sola lettura, di dimensioni ridotte.
ES8505202A1 (es)	1985-05-16	Un procedimiento para la preparacion de nuevos 5-amino o amino sustituidos-imidazoles.
SE8005784L (sv)	1981-02-18	Heterocykliska foreningar
DE59108566D1 (de)	1997-04-03	Heteroarylmethylbenzole-Aromatasehemmer
FI821288L (fi)	1982-10-15	Fenetanolaminderivat, deras framstaellning och deras terapeutiska anvaendning
ES2080336T3 (es)	1996-02-01	Derivados de metilpiperazinoazepina, su preparacion y su utilizacion.
ES8501607A1 (es)	1984-12-01	Procedimiento para la obtencion de heterociclos nitrogenosos de 5 miembros
FI834362A0 (fi)	1983-11-29	Vid behandling av hoegt blodtryck anvaendbara foereningar
DK313587D0 (da)	1987-06-19	Tetrahydrobenzothiazolforbindelser, deres fremstilling og anvendelse
FI840743A0 (fi)	1984-02-23	N-(3-trifluormetylfenyl)-n'-propargylpiperazin, dess framstaellning och anvaendning
FI880987A0 (fi)	1988-03-03	1-(1-aryl-2-hydroxietyl) imidazoler och deras salter, foerfarande foer deras framstaellning, laekemedel innehaollande dessa foereningar och deras anvaendning.
ES517874A0 (es)	1983-12-01	Procedimiento de preparacion de derivados de diaza-3,7a-cicloherta-(j,k)-fluorenos.
SE7602760L (sv)	1976-09-13	Monosubstituerat piperazinderivat

Legal Events

Date	Code	Title	Description
1995-01-31	NUG	Patent has lapsed	Ref document number: 8101311-2 Effective date: 19910911 Format of ref document f/p: F

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1995-01-31

NUG

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