RU2291617C2 - Agent for pest and acaridae controlling - Google Patents

Abstract

FIELD: agriculture, organic chemistry.

SUBSTANCE: invention relates to agent for pest and acaridae controlling containing mixture of a) compound of formula I

, wherein X represents C₁-C₄-alkyl; W, Y, and Z are independently hydrogen or C₁-C₄-alkyl; A and B together with the hydrogen atom to which they are attached form saturated C₃-C₆-cycloalkyl monosubstituted with (C₁-C₄-alkoxyl; D represents hydrogen; G represents hydrogen or group

, wherein M is oxygen; R² is C₁-C₈-alkyl; and b) compound selected from group containing acrinatrin, cypermetrin, alpha-cypermetrin, zeta-cypermetrin, cyflutrin, beta-cyflutrin,, deltametrin, lambda-cyhalotrin, phempropatrin, and biphentrin, wherein a) and b) mass ratio is from 25:1 to 1:1.

EFFECT: agent with synergic effect and increased activity.

3 cl, 12 tbl, 5 ex

Description

This invention relates to new combinations of active substances, consisting of known cyclic ketoenols, on the one hand, and other known insecticidal active substances, on the other hand, effective in controlling animal pests, such as insects and unwanted acaricides.

Certain cyclic ketoenols are known to have herbicidal, insecticidal and acaricidal properties. The effectiveness of these substances, however, in some cases when applied in small quantities is insufficient.

Unsubstituted, bicyclic derivatives of 3-arylpyrrolidin-2,4-dione (EP-A 355599 and EP-A 415211), as well as substituted monocyclic derivatives of 3-arylpyrrolidin-2,4-dione (EP- A 377893 and EP-A 442077).

In addition, polycyclic derivatives of 3-arylpyrrolidin-2,4-dione (EP-A 422073), as well as derivatives of 1H-arylpyrrolidinedione (EP-A 456063, EP-A 521334, EP-A 596298, EP-A 613884, EP are known -A 613885, WO 94/01997, WO 95/26954, WO 95/20572, EP-A 0668267, WO 96/25395, WO 96/35664, WO 97/01535, WO 97/02243, WO 97/36868, WO 97/43275, WO 98/05638, WO 98/06721, WO 98/25928, WO 99/16748, WO 99/24437, WO 99/43649, WO 99/48869 and WO 99/55673).

In addition, it is known that numerous heterocycles, organotin compounds, benzoylureas and pyrethroids have insecticidal or acaricidal properties (cf. WO 93/22297, WO 93/10083, DE-A 2641343, EP-A 347488, EP-A 210487, US-A 3264177 and EP-A 234045). However, the effectiveness of these substances is not always satisfactory.

Found that the compounds of formula (I)

in which X represents a halogen, alkyl, alkoxyl, haloalkyl, haloalkoxyl or cyano group,

W, Y and Z mean, independently of one another, hydrogen, halogen, alkyl, alkoxyl, haloalkyl, haloalkoxyl or cyano,

And means hydrogen, unsubstituted or halogen-substituted alkyl, alkoxyl, saturated, optionally substituted cycloalkyl, in which, if necessary, at least one atom of the ring is replaced by a heteroatom,

B means hydrogen or alkyl,

A and B, together with the carbon atom to which they are attached, form a saturated or unsaturated, unsubstituted or substituted ring, optionally including at least one heteroatom,

D means hydrogen or an unsubstituted or substituted radical from the series alkyl, alkenyl, alkoxyalkyl, saturated cycloalkyl, in which, if necessary, one or more ring units are replaced by heteroatoms,

A and D, together with the atoms to which they are attached, form a saturated or unsaturated ring, optionally containing at least one heteroatom, unsubstituted or substituted at A, D - position of the ring,

G means hydrogen (a) or one of the groups

E (e) or

in which E means a metal or ammonium ion,

L is oxygen or sulfur,

M means oxygen or sulfur,

R ¹ means unsubstituted or halogen-substituted alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl, polyalkoxyalkyl or unsubstituted or substituted by halogen, alkyl or alkoxyl cycloalkyl, which optionally contains at least one heteroatom, unsubstituted or substituted phenyl, phenylalkyl, heteroalkyl, heteroaryl ,

R ² means unsubstituted or halogen-substituted alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or means unsubstituted or substituted cycloalkyl, phenyl or benzyl,

R ³ means alkyl, unsubstituted or substituted by halogen, or means phenyl, unsubstituted or substituted,

R ⁴ and R ⁵ mean, independently of one another, unsubstituted or halogen-substituted alkyl, alkoxyl, alkylamino, dialkylamino, alkylthio, alkenylthio, cycloalkylthio or mean unsubstituted or substituted phenyl, benzyl, phenoxyl or phenylthio and

R ⁶ and R ⁷ mean, independently of one another, hydrogen, unsubstituted or halogen-substituted alkyl, cycloalkyl, alkenyl, alkoxyl, alkoxyalkyl, mean unsubstituted or substituted phenyl, mean unsubstituted or substituted benzyl or together with the N-atom to which they are bonded form an unsubstituted or substituted ring, which, if necessary, includes oxygen or sulfur,

and pyrethroids, preferably the following:

1. Acrinatrin

known from EP-A 048186,

and / or

2. Alpha cypermethrin

known from EP-A 067461,

and / or

3. Betaciflutrin

known from EP-A 206149,

and / or

4. Cigalotrin

known from DE-A 2802962,

and / or

5. Cypermethrin

known from DE-A 2326077,

and / or

6. Deltamethrin

known from DE-A 2326077,

and / or

7. Esfenvalerate

known from DE-A 2737297,

and / or

8. Etofenprox

known from DE-A 3117510,

and / or

9. Fenpropatrin

known from DE-A 2231312,

and / or

10. Fenvalerate

known from DE-A 2335347,

and / or

11. Flucytrinate

known from DE-A 2757066,

and / or

12. Lambda-cygalotrin

known from EP-A 106469, and / or

13. Permethrin

known from DE-A 2326077,

and / or

14. Taufluvalinate

known from EP-A 038617,

and / or

15. Thralomethrin

known from DE-A 2742546,

and / or

16. Zeta cypermethrin

known from EP-A 026542,

and / or

17. Tsiflutrin

known from DE-A 2709264,

and / or

18. Bifentrin

known from EP-A 049977,

and / or

19. Cycloprotrin

known from DE-A 2653189,

and / or

20. Eflusilanate

known from DE-A 3604781,

and / or

21. Fubfenprox

known from DE-A 3708231,

and / or

22. Pyrethrin

R = —CH ₃ or —CO ₂ CH ₃ ,

R ₁ = —CH = CH ₂ or —CH ₃ , or —CH ₂ CH ₃ ,

known from the Pesticide manual, 1977, 11th edition, p. 1056, and / or

23. Resmethrin

known from GB-A 1168797,

which have good insecticidal and acaricidal properties.

It was unexpectedly discovered that the insecticidal and acaricidal efficacy of the combinations of active substances according to the invention is significantly higher than the sum of the efficiencies of the individual active substances. There is an unpredictable real synergistic effect, and not just an increase in efficiency.

The combination of active substances according to the invention contain, along with at least one active substance of the formula (I), at least one active substance from compounds from 1 to 23.

Combinations of active substances containing compounds of formula (I) are preferred in which the radicals have the following meanings:

W is preferably hydrogen, (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) -alkoxyl, chloro, bromo or fluoro,

X is preferably (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) -alkoxyl, (C ₁ -C ₄ ) -haloalkyl, fluoro, chloro or bromo,

Y and Z preferably mean, independently of one another,

hydrogen, (C ₁ -C ₄ ) -alkyl, halogen, (C ₁ -C ₄ ) -alkoxyl or (C ₁ -C ₄ ) -haloalkyl,

A means preferably hydrogen or unsubstituted or substituted by a halogen of (C ₁ -C ₆ ) -alkyl or (C ₃ -C ₈ ) -cycloalkyl,

B means preferably hydrogen, methyl or ethyl,

A, B and the carbon atom to which they are attached preferably mean saturated (C ₃ -C ₆ ) cycloalkyl unsubstituted or substituted once or twice by (C ₁ -C ₄ ) alkyl, trifluoromethyl or (C ₁ -C ₄ ) -alkoxyl, in which, if necessary, one ring unit is replaced by oxygen or sulfur,

D is preferably hydrogen, unsubstituted or substituted by fluorine or chlorine (C ₁ -C ₆ ) -alkyl, (C ₃ -C ₄ ) -alkenyl or (C ₃ -C ₆ ) -cycloalkyl,

A and D together mean preferably unsubstituted or substituted with methyl (C ₃ -C ₄ ) -alkanediyl, in which, if necessary, one methylene group is replaced by sulfur,

G means preferably hydrogen (a) or one of the groups

E (e) or

especially mean (a), (b), (c) or (g), in which

E means a metal or ammonium ion,

L is oxygen or sulfur,

M means oxygen or sulfur,

R ¹ means preferably unsubstituted or substituted by halogen (C ₁ -C ₁₀ ) -alkyl, (C ₂ -C ₁₀ ) -alkenyl, (C ₁ -C ₄ ) -alkoxy- (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) -alkylthio- (C ₁ -C ₄ ) -alkyl or (C ₃ -C ₆ ) -cycloalkyl unsubstituted or substituted by fluorine, chlorine, (C ₁ -C ₄ ) -alkyl or (C ₁ -C ₂ ) -alkoxyl,

means phenyl unsubstituted or substituted by fluorine, chlorine, bromine, cyano, nitro, C ₁ -C ₄ -alkyl, (C ₁ -C ₄ ) alkoxyl, trifluoromethyl or trifluoromethoxy,

means pyridyl or thienyl unsubstituted or substituted with chlorine or methyl,

R ² is preferably unsubstituted or substituted by fluorine or chlorine (C ₁ -C ₁₀ ) -alkyl, (C ₂ -C ₁₀ ) -alkenyl, (C ₁ -C ₄ ) -alkoxy- (C ₂ -C ₄ ) -alkyl,

means (C ₅ -C ₆ ) -cycloalkyl unsubstituted or substituted with methyl or methoxy, or

means phenyl or benzyl unsubstituted or substituted by fluorine, chlorine, bromine, cyano, nitro, (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) -alkoxyl, trifluoromethyl or trifluoromethoxy,

R ³ means preferably (C ₁ -C ₄ ) -alkyl unsubstituted or substituted by fluorine, or means phenyl unsubstituted or substituted by fluorine, chlorine, bromine, (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) - alkoxyl, trifluoromethyl, trifluoromethoxyl, cyano or nitro group,

R ⁴ is preferably (C ₁ -C ₄ ) -alkyl, (C ₁ -C ₄ ) -alkoxyl, (C ₁ -C ₄ ) -alkylamino, (C ₁ -C ₄ ) -alkylthio, unsubstituted or substituted by fluorine or chlorine, or mean phenyl, phenoxyl or phenylthio, unsubstituted or substituted by fluorine, chlorine, bromine, nitro, cyano, (C ₁ -C ₄ ) alkoxyl, trifluoromethoxyl, (C ₁ -C ₄ ) -alkylthio, (C ₁ -C ₄ ) -haloalkylthio, (C ₁ -C ₄ ) -alkyl or trifluoromethyl,

R ⁵ is preferably (C ₁ -C ₄ ) alkoxy or (C ₁ -C ₄ ) thioalkyl,

R ⁶ is preferably (C ₁ -C ₆ ) -alkyl, (C ₃ -C ₆ ) -cycloalkyl, (C ₁ -C ₆ ) -alkoxyl, (C ₃ -C ₆ ) alkenyl, (C ₁ -C ₄ ) -alkoxy- (C ₁ -C ₄ ) -alkyl,

R ⁷ is preferably (C ₁ -C ₆ ) -alkyl, (C ₃ -C ₆ ) -alkenyl or (C ₁ -C ₄ ) -alkoxy- (C ₁ -C ₄ ) -alkyl,

R ⁶ and R ⁷ together mean preferably a (C ₃ -C ₆ ) alkylene radical in which, if necessary, one carbon atom is replaced by oxygen or sulfur and which is unsubstituted or substituted by methyl or ethyl,

W means particularly preferably hydrogen, methyl, ethyl, chlorine, bromine or methoxy,

X is particularly preferably chlorine, bromine, methyl, ethyl, propyl, isopropyl, methoxyl, ethoxyl or trifluoromethyl,

Y and Z are particularly preferably independently of one another hydrogen, fluoro, chloro, bromo, methyl, ethyl, propyl, isopropyl, trifluoromethyl or methoxy,

And means particularly preferably methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl, tert-butyl, cyclopropyl, cyclopentyl or cyclohexyl,

B means particularly preferably hydrogen, methyl or ethyl,

A, B and the carbon atom to which they are attached mean particularly preferably saturated, unsubstituted or singly substituted with methyl, ethyl, methoxyl, ethoxyl, propoxyl or butoxyl C ₆ -cycloalkyl, in which, if necessary, one ring unit is replaced by oxygen,

D is particularly preferably hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, allyl, cyclopropyl, cyclopentyl or cyclohexyl,

A and D together particularly preferably mean unsubstituted or substituted with methyl (C ₃ -C ₄ ) -alkanediyl,

G means particularly preferably hydrogen (a) or one of the groups

или

or

in which M means oxygen or sulfur,

R ¹ is particularly preferably (C ₁ -C ₈ ) -alkyl, (C ₂ -C ₄ ) -alkenyl, methoxymethyl, ethoxymethyl, ethylthiomethyl, cyclopropyl, cyclopentyl or cyclohexyl,

means phenyl unsubstituted or substituted by fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, methoxy, trifluoromethyl or trifluoromethoxy,

means pyridyl or thienyl unsubstituted or substituted with chlorine or methyl,

R ² is particularly preferably (C ₁ -C ₈ ) -alkyl, (C ₂ -C ₄ ) -alkenyl, methoxyethyl, ethoxyethyl or is phenyl or benzyl,

R ⁶ and R ⁷ mean independently of one another, particularly preferably methyl, ethyl or together mean a C ₅ alkylene radical in which the C ₃ methylene group is replaced by oxygen,

W most preferably means hydrogen or methyl,

X most preferably means chlorine, bromine or methyl,

Y and Z mean, independently of one another, most preferably hydrogen, chlorine, bromine or methyl,

A, B and the carbon atom to which they are attached, most preferably mean saturated, unsubstituted or singly substituted with methyl, methoxy, ethoxyl, propoxyl or butoxyl C ₆ -cycloalkyl, in which, if necessary, one ring unit is replaced by oxygen,

D is most preferably hydrogen,

G means most preferably hydrogen (a) or one of the groups

или

or

in which M means oxygen or sulfur,

R ¹ is most preferably (C ₁ -C ₈ ) -alkyl, (C ₂ -C ₄ ) -alkenyl, methoxymethyl, ethoxymethyl, ethylmethylthio, cyclopropyl, cyclopentyl, cyclohexyl or

means phenyl unsubstituted or substituted by fluorine, chlorine, bromine, methyl, methoxyl, trifluoromethyl, trifluoromethoxyl, cyano or nitro,

means pyridyl or thienyl unsubstituted or substituted with chlorine or methyl,

R ² is most preferably (C ₁ -C ₈ ) -alkyl, (C ₂ -C ₄ ) -alkenyl, methoxyethyl, ethoxyethyl, phenyl or benzyl,

R ⁶ and R ⁷ mean, independently of one another, most preferably methyl, ethyl or together mean a C ₅ alkylene radical in which the C ₃ methylene group is replaced by oxygen.

Especially preferred combinations of active substances containing compounds of formula (I)

in which W, X, Y, Z, R and G have the meanings given in table 1,

Table 1 Example No. W X Y Z R G T. pl., ° C I - 1 H Br 5-CH ₃ N OCH ₃ СО-i-С ₃ Н ₇ 122 I - 2 H Br 5-CH ₃ N OCH ₃ CO ₂ -C ₂ H ₅ 140-142 I - 3 H CH ₃ 5-CH ₃ N OCH ₃ N > 220 I - 4 H CH ₃ 5-CH ₃ N OCH ₃ CO ₂ —C ₂ H ₅ 128 I - 5 CH ₃ CH ₃ 3-br N OCH ₃ N > 220 I - 6 CH ₃ CH ₃ 3-cl N OCH ₃ N 219 I - 7 H Br 4-CH ₃ 5-CH ₃ OCH ₃ СО-i-С ₃ Н ₇ 217 I - 8 H CH ₃ 4-cl 5-CH ₃ OCH ₃ CO ₂ —C ₂ H ₅ 162 I - 9 H CH ₃ 4-CH ₃ 5-CH ₃ OCH ₃

Oil I - 10 CH ₃ CH ₃ 3-CH ₃ 4-CH ₃ OCH ₃ N > 220 I - 11 H CH ₃ 5-CH ₃ N OC ₂ H ₅

Oil I - 12 CH ₃ CH ₃ 3-br N OC ₂ H ₅ СО-i-С ₃ Н ₇ 212-214 I - 13 H CH ₃ 4-CH ₃ 5-CH ₃ OC ₂ H ₅ CO-n-Pr 134 I - 14 H CH ₃ 4-CH ₃ 5-CH ₃ OC ₂ H ₅ CO-i-Pr 108 I - 15 H CH ₃ 4-CH ₃ 5-CH ₃ OC ₂ H ₅ CO-s-Pr 163

and at least one active substance I-23.

Combinations of active substances may also contain other fungicidal, acaricidal or insecticidal active ingredients.

In the event that the active substances in the combinations of active substances according to the invention are in certain weight ratios, the synergistic effect is especially pronounced. However, the weight ratio of active substances can vary in a relatively large range. Typically, the combinations according to the invention contain the active substances of formula (I) and an additional partner in the preferred and particularly preferred ratio shown in table 2.

Mixing ratios are weight ratios. The ratio should be understood as the ratio of the active substance of formula (I) to an additional partner.

table 2 Additional partner Preferred Mixing Ratio Particularly preferred mixing ratio Acrinatrin 20: 1 to 1:50 10: 1 to 1: 1 Alpha cypermethrin 50: 1 to 1: 5 10: 1 to 1: 1 Betaciflutrin 50: 1 to 1: 5 10: 1 to 1: 1 Cigalotrin 50: 1 to 1: 5 10: 1 to 1: 1 Cypermethrin 50: 1 to 1: 5 10: 1 to 1: 1 Deltamethrin 50: 1 to 1: 5 10: 1 to 1: 1 Esfenvalerate 50: 1 to 1: 5 10: 1 to 1: 1 Etofenprox 10: 1 to 1:10 5: 1 to 1: 5 Fenpropatrine 10: 1 to 1:10 5: 1 to 1: 5 Fenvalerate 20: 1 to 1: 5 10: 1 to 1: 1 Flucytrinate 50: 1 to 1: 5 10: 1 to 1: 1 Lambda cygalothrin 50: 1 to 1: 5 10: 1 to 1: 1 Permethrin 10: 1 to 1:10 5: 1 to 1: 5 Tau fluvalinate 20: 1 to 1: 5 10: 1 to 1: 2 Tralomethrin 50: 1 to 1: 5 10: 1 to 1: 1 Zeta cypermethrin 50: 1 to 1: 5 10: 1 to 1: 2 Tsiflutrin 50: 1 to 1: 5 10: 1 to 1: 1 Bifenthrin 10: 1 to 1:10 10: 1 to 1: 1 Cycloprotrin 10: 1 to 1:10 5: 1 to 1: 5 Efluzilanate 10: 1 to 1:10 5: 1 to 1: 5 Fubfenprox 10: 1 to 1:10 5: 1 to 1: 5 Pyrethrin 50: 1 to 1:10 5: 1 to 1: 1 Rezmetrin 50: 1 to 1:10 5: 1 to 1: 1

The combinations of active substances according to the invention are suitable for controlling animal pests, preferably with arthropods and nematodes, especially with insects and arachnids found in agriculture, veterinary medicine, in forests, in the protection of supplies and materials, and in the field of hygiene. They are effective in relation to species with normal sensitivity and resistant species, as well as in relation to all or to individual stages of development. The above pests include the following.

From the order Isopoda, for example, Oniscus asellus, Armadillidium vulgare, Porcellio scaber.

From the order of Diplopoda, for example, Blaniulus guttulatus.

From the order Chilopoda, for example, Geophilus carpophagus, Scutigera spp.

From the order Symphyla, for example, Scutigerella immaculata.

From the Thysanura order, for example, Lepisma saccharina.

From the order Collembola, for example, Onychiurus armatus.

From the order Orthoptera, for example, Acheta domesticus, Gryllotalpa spp., Locusta migratoria migratorioides, Melanoplus spp., Schistocerca gregaria.

From the order Blattaria, for example, Blatta orientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica.

From the order Dermaptera, for example, Forficula auricularia.

From the order Isoptera, for example, Reticulitermes spp.

From the order Phthiraptera, for example, Pediculus humanus corporis, Haematopinus spp., Linognathus spp., Trichodectes spp., Damalinia spp.

From the order Thysanoptera, for example, Hercinothrips femoralis, Thrips tabaci, Thrips palmi, Frankliniella accidentalis.

From the order Heteroptera, for example, Eurygaster spp., Dysdercus intermedius, Piesma quadrata, Cimex lectularius, Rhodnius prolixus, Triatoma spp.

From the order Homoptera, for example, Aleurodes brassicae, Bemisia tabaci, Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis, Aphis fabae. Aphis pomi, Eriosoma lanigerum, Hyalopterus arundinis. Phylloxera vastatrix, Pemphigus spp., Macrosiphum avenae, Myzus spp., Phorodon humuli, Rhopalosiphum padi, Empoasca spp., Euscelis bilobatus, Nephotettix cincticeps, Lecanium corni, Saissetia oleidiepéléeelliapéléatelapetella papiella papelioeta, leeium papelioet, heliella papelioet, heliella papelioeta, heliapaeella papelioeta, leocium papillonaceae, leocium papillonaceae, leocium papillonaceae, papillonum ., Psylla spp.

From the order Lepidoptera, for example, Pectinophora gossypiella, Bupalus piniarius, Cheimatobia brumata, Lithocolletis blancardella, Hyponomeuta padella, Plutella xylostella, Malacosoma neustria, Euproctis sppisll., Budmul sppll. ., Earias insulana, Heliothis spp., Mamestra brassicae, Panolis flammea, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Epideia kuehniella, Gellophella tella pella tella pella pella , Cacoecia podana, Capua reticulana, Choristoneura fumiferana, Clysia ambiguella, Homona magnanima, Tortrix viridana, Cnaphalocerus spp., Oulema oryzae.

From the order Coleoptera, for example, Anobium punctatum, Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus, Hylotrupes bajulus, Agelastica alni, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica sphna pppippsa pppippsa pppippi sppsa, sppp. , Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchus assimilis, Hypera postica, Dermestes spp., Trogoderma spp., Anthrenus spp., Attagenus spp., Lyctus spp., Meligethes aeneus, holtuspole, Pole, choleptus pepius, Pomegranateum spp. Tribolium spp., Tenebrio molitor, Agriotes spp., Conoderus spp., Melolontha melolontha, Amphimallon solstitialis, Costelytra zealandica, Lissorhoptrus oryzophilus.

From the Hymenoptera order, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

From the order Diptera, for example, Aedes spp., Anopheles spp., Culex spp., Drosophila melanogaster, Musca spp., Fannia spp., Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebra spp., Gastrophilus sppa. Hy ., Stomoxys spp., Oestrus spp., Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortulanus, Oscinella frit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae, Tipula paludosa, Hulemyiappi. .

From the order Siphonaptera, for example, Xenopsylla cheopis, Ceratophyllus spp.

From the class Arachnida, e.g., Scorpio maurus, Latrodectus mactans, Acarus siro, Argas spp., Ornithodoros spp., Dermanyssus gallinae, Eriophyes ribis, Phyllocoptruta oleivora, Boophilus spp., Rhipicephalus sompp., Amb. Spppp. Amb. ., Psoroptes spp., Chorioptes spp., Sarcoptes spp., Tarsonemus spp., Bryobia praetiosa, Panonychus spp., Tetranychus spp., Hemitarsonemus spp., Brevipalpus spp.

Nematodes that parasitize plants include, for example, Pratylenchus spp., Radopholus similis, Ditylenchus dipsaci, Tylenchulus semipenetrans, Heterodera spp., Globodera spp., Meloidogyne spp., Aphelenchoides spp., Longidorus spp .pppp. ., Bursaphelenchus spp.

Combinations of active substances can be converted into usual forms, such as solutions, emulsions, spray powders, suspensions, powders, dusting agents, pastes, soluble powders, granules, suspension emulsion concentrates, natural or synthetic substances impregnated with active substances, and also the smallest capsules in polymeric substances.

These forms are prepared by known methods, for example, by mixing the active substances with diluents, i.e. with liquid solvents and / or solid carriers, optionally using surfactants, i.e. emulsifying and / or dispersing agents, and / or foaming agents.

In the case of using water as a diluent, for example, organic solvents can also be used as an aid to improving dissolution. As solvents, aromatic compounds, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatic compounds and chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chloroethenes or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, for example petroleum fractions, are essentially meant. and vegetable oils, alcohols, such as butanol or glycol, as well as their ethers and esters, ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexano m, highly polar solvents such as dimethylformamide and dimethyl sulfoxide, as well as water.

Solid carriers include, for example, ammonium salts or grinding of natural minerals such as kaolins, alumina, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and grinding of synthetic minerals such as highly dispersed silicic acid, aluminum oxide and silicates, as solid carriers for granules, refer to crushed and fractionated natural rock, such as calcite, marble, pumice, sepiolis, dolomite, as well as synthetic granules from inorganic or organic mu ki, as well as granules made from organic material such as sawdust, coconut shells, corn cobs and tobacco stalks; as emulsifying and / or foaming agents are meant, for example, nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid ester, polyoxyethylene fatty alcohol ester, for example alkylaryl polyglycol ether, alkyl sulfonates, alkyl sulfates, arylsulfonates, as well as protein hydrolysates; as dispersants, for example, spent lignin-sulfite liquors and methyl cellulose are meant.

In the formulations, adhesion improvers are used, such as carboxymethyl cellulose, natural or synthetic powdered, granular or latex polymers such as gum arabic, polyvinyl alcohol, polyvinyl acetate, as well as natural phospholipids such as cephalins and lecithins, and synthetic phospholipids. Other additives may include mineral and vegetable oils.

Dyes such as inorganic pigments, for example, iron oxide, titanium oxide, ferrocyan blue, and organic dyes, such as alizarin, azo, and metal phthalocyanine dyes, and trace amounts of micronutrients, such as salts of iron, manganese, boron, and copper, are also used. , cobalt, molybdenum and zinc.

The formulations typically contain from 0.1 to 95 wt.% The active substance, preferably from 0.5 to 90 wt.%.

The combinations of active substances according to the invention can be presented both in the form of conventional commercial formulations, and in the form of ready-to-use forms prepared from them in a mixture with other active substances, such as insecticides, attractants, sterilizing substances, bactericides, acaricides, nematicides, fungicides, plant growth regulating agents or herbicides. Insecticides include, for example, phosphoric acid esters, carbamates, carboxylic acid esters, chlorinated hydrocarbons, phenylureas, substances obtained by microorganisms, and others.

It is also possible mixing with other active substances, such as herbicides, or with fertilizers and growth regulators.

The combinations of active substances according to the invention can further be used as insecticides in the form of commercially available compositions, as well as in the form of preparations prepared from them for use in a mixture with synergists. Synergists are those compounds whose action increases the effectiveness of the active substances, while the added synergist itself may not be active.

The content of the active substance in the forms for use obtained from commercial formulation formulations can vary widely. The concentration of active substances in the forms for use is from 0.0000001 to 95 wt.% The active substance, preferably from 0.0001 to 1 wt.%.

Application is carried out in a conventional manner suitable for the application form.

When used against pests that are hazardous to hygiene or stored crop stocks, combinations of active substances show a very good residual effect on wood and on the ground, as well as good alkali stability on lime substrates.

The combinations of active substances according to the invention act not only against pests that are dangerous to plants, hygiene or stored stocks of crops, but also in veterinary medicine against animal parasites (ectoparasites), such as pasture mites, skin mites, scab and scabies mites, redshields , flies (biting and licking), parasitic larvae of flies, lice, lice-eaters, lice-flies and fleas. These parasites include the following.

From the order Anoplurida, for example, Haematopinus spp., Linognathus spp., Pediculus spp., Phtirus spp., Solenopotes spp.

From the order of Mallophagida and suborders Amblycerina, as well as Ischnocerina, for example, Trimenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Werneckiella spp., Lepikentron spp., Damalina spp., Trichodectes spp., Felicola

From the order Diptera and suborders Nematocerina, as well as Brachycerina, for example, Aedes spp., Anopheles spp., Culex spp., Simulium spp., Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp., Chrysomppra. spp., Atylotus spp., Tabanus spp., Haematopota spp., Philipomyia spp., Braula spp., Musca spp., Hydrotaea spp., Stomoxys spp., Haematobia spp., Morellia spp., Fannia spp., Glossina spp. , Calliphora spp., Lucilia spp., Chrysomyia spp., Wohlfahrtia spp., Sarcophaga spp., Oestrus spp., Hypodernia spp., Gasterophilus spp., Hippobosca spp., Lipoptena spp., Melophagus spp.

From the order Siphonapterida, for example, Pulex spp., Ctenocephalides spp., Xenopsylla spp., Ceratophyllus spp.

From the order Heteropterida, for example, Cimex spp., Triatoma spp., Rhodnius spp., Panstrongylus spp.

From the order Blattarida, for example, Blatta orientalis, Periplaneta americana, Blatella germanica, Supella spp.

From the subclass Acaria (Acarida) and from the Meta- and Mesostigmata orders, for example, Argas spp., Ornithodorus spp., Otobius spp., Ixodes spp., Amblyomma spp., Boophilus spp., Dermacentor spp., Haemophysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp., Raillietia spp., Pneumonyssus spp., Sternostoma spp., Varroa spp.

From the orders Actinedida (Prostigmata) and Acaridida (Astigmata), for example, Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp., Psorergates spp., Demodex spp., Trombicula spp., Listrophorus spp., Acarus Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp., Otodectes spp., Sarcoptes spp., Notoedres spp., Knemidocoptes spp., Cytodites spp., Lamin

The combinations of active substances according to the invention are also suitable for controlling blood-sucking arthropods that attack useful farm animals, for example, cows, sheep, goats, horses, pigs, donkeys, camels, buffaloes, rabbits, chickens, turkeys, ducks, geese, bees, other domestic animals, such as dogs, cats, domestic birds, aquarium fish, as well as so-called experimental animals, such as hamsters, guinea pigs, rats and mice. As a result of the fight against these blood-sucking arthropods, they achieve that they avoid deaths and reduce production losses (in the production of meat, milk, wool, skin, eggs, honey, and so on). Thus, the use of combinations of active substances according to the invention makes it possible for a more cost-effective and simple livestock maintenance.

The use of combinations of active substances according to the invention takes place in veterinary practice by the usual methods when introduced into the intestines, for example, in the form of tablets, capsules, drinks, impregnations, granules, pastes, pills, with food, petals, with parenteral administration, for example, by injection (intramuscularly, with a catheter, intravenously, intraperitoneally and others), in the form of implants, when inserted into the nose, during skin use, for example, by dipping or bathing (Dippen), spraying (Spray), dousing from above (Pour-on and Spot-on), washing powdering as well e using surfactants containing bodies of some form, such as collars, ear marks, tail marks, tape on different parts of the body, bandages, devices for labeling, and so on.

When used for livestock, poultry, domestic animals and the like, combinations of active substances in the form of ready-made forms (for example, powders, emulsions, flowing agents) that contain active substances in an amount of from 1 to 80% by weight, directly or after 100- to 10,000-fold dilutions or use as a chemical bath.

In addition, it was found that combinations of active substances according to the invention have high insecticidal activity against insects that destroy technical materials.

By way of example and preferably, but not limited to, the following insects should be mentioned:

beetles, such as Hylotrupes bajulus, Chlorophorus pilosis, Anobium punctatum, Xestobium rufovillosum, Ptilinus pecticornis, Dendrobium pertinex, Ernobius mollis, Priobium carpini, Lyctus brunneus, Lyctus african coliceles, Lyctus planicollesollis, Lyctus planicollesollis colis cholecollis, Lyctus planicollis colis lecollis colicollis, Lyctus planicollis colis cholecollis spec. Tryptodendron spec. Apate monachus, Bostrychus capucins, Heterobostrychus brunneus, Sinoxylon spec. Dinoderus minutus,

hymenoptera, such as Sirex juvencus, Urocerus gigas, Urocerus gigas taignus, Urocerus augur,

      termites such as Kalotermes flavicollis, Cryptotermes brevis, Heterotermes indicola, Reticulitermes flavipes, Reticulitermes santonensis, Reticulitermes lucifugus, Mastotermes darwiniensis, Zooterroopsis nevadensis, Coptotermes formosanus

      bristles, such as Lepisma saccharina.

Under the technical materials in connection with the foregoing, it should be understood materials, such as preferably plastics, adhesives, clays, paper and cardboard, leather, wood, wood processing products and paints and varnishes.

Particularly preferably, protective materials against insect attack are meant in order to protect wood and wood processing products.

Under wood and wood processing products that can be protected by the means according to the invention, respectively, mixtures containing these means should, for example, be understood

scaffolding, wooden beams, railway sleepers, bridge details, ship partitions, wooden carts, boxes, pallets, containers, telephone poles, wooden cladding, wooden windows and doors, plywood, mounting plates, joinery and wood products that, like as a rule, find application in housing construction and in carpentry work.

Combinations of active substances can be used as such in the form of concentrates or commonly used forms, such as powders, granules, solutions, suspensions, emulsions or pastes.

The above forms can be made by known methods, for example, by mixing the active substances with at least one solvent, respectively, a diluent, emulsifier, dispersing and / or binding or fixing agent, water repellent, if necessary, desiccant or UV stabilizer and, if necessary, dyes and pigments, as well as other processing aids.

Insecticides or concentrates used to protect wood and wood products contain the active substance according to the invention in a concentration of from 0.0001 to 95 wt.%, Preferably from 0.001 to 60 wt.%.

The amount of agent used, respectively, of the concentrate, depends on the type and distribution of insects and on the habitat. The optimum amount to be applied is determined using test series. As a rule, it is sufficient to apply from 0.0001 to 20 wt.%, Preferably from 0.001 to 10 wt.%, Of the active substance, in terms of the protected material.

The solvent and / or diluent is an organic chemical solvent or solvent mixture, and / or an oily or oily refractory organic chemical solvent or solvent mixture, and / or a polar organic chemical solvent or solvent mixture, and / or water and, if necessary, an emulsifier and / or wetting agent.

As organic chemical solvents, preferably oily or oily solvents with a volatility coefficient above 35 and with a flash point above 30 ° C, preferably above 45 ° C are used. As such non-volatile, water-insoluble oily and oily solvents, appropriate oils or fractions thereof containing aromatic compounds or mixtures of solvents containing oils, preferably testbenzene, kerosene and / or alkylbenzene, are used.

Preferred for the use of oil with a boiling point in the range from 170 to 220 ° C, testbenzene with a boiling point in the range from 170 to 220 ° C, spindle oil with a boiling point in the range from 250 to 350 ° C, kerosene, respectively, aromatic compounds with boiling point in the region from 160 to 280 ° C, turpentinol and the like.

In one preferred embodiment, liquid aliphatic hydrocarbons with a boiling point in the range of 180 to 210 ° C or high boiling mixtures of aromatic and aliphatic hydrocarbons with a boiling point in the range of 180 to 220 ° C and / or spindle oil and / or monochloronaphthalene are used, preferably α-monochloronaphthalene.

Organic non-volatile oily or oily solvents with a volatility coefficient above 35 and with a flash point above 30 ° C, preferably above 45 ° C, can be partially replaced by low- and medium-volatile organic chemical solvents, provided that the solvent mixture also has a volatility coefficient above 35 and a flash point above 30 ° C, preferably above 45 ° C, and that the mixture can be dissolved or emulsified in this solvent mixture.

In one preferred embodiment, a portion of the organic chemical solvent or mixture of solvents is replaced with an aliphatic polar organic chemical solvent or mixture of solvents. Aliphatic organic chemical solvents containing hydroxyl and / or ester and / or ester groups, such as, for example, glycol ether, ester or the like, are preferably used.

As organic chemical binders, within the framework of this invention, known per se, diluted with water and / or soluble or dispersible, respectively, artificial resins emulsified with used organic chemical solvents and / or binder drying oils are used. Binder agents consisting of or containing acrylic resin, vinyl resin, for example polyvinyl acetate, polyester resin, polycondensation resin or polyaddition resin, polyurethane resin, alkyd resin, suitably modified alkyd resin, phenolic resin, hydrocarbon resin such as indene, are particularly suitable. -coumarone resin, silicone resin, drying vegetable and / or drying oils, and / or physically drying binders based on natural and / or artificial resins.

An artificial resin in the form of an emulsion, dispersion or solution is used as a binder. As binders, bitumen or bituminous substances up to 10 wt.% Are also used. Additionally, well-known dyes, pigments, water-repellent agents, odor-corrective substances, and inhibitors, respectively corrosion protection agents and the like, are used.

Preferably according to the invention, the content in the agent or in the concentrate as organic, chemical binders of at least one alkyd resin, respectively a modified alkyd resin and / or a drying vegetable oil. Alkyd resins with an oil content of more than 45% by weight, preferably from 50 to 68% by weight, are preferably used according to the invention.

Said binder may be completely or partially replaced by a fixing agent (mixture) or a plasticizing agent (mixture). These additives should prevent the volatilization of the active substances, as well as crystallization, respectively, their deposition. Preferably they replace from 0.01 to 30% of the binder (in terms of 100% of the binder used).

Plasticizers are selected from the chemical classes of phthalic acid esters such as dibutyl, dioctyl or benzyl butyl phthalate, phosphoric esters such as tributyl phosphate, adipic acid esters such as di- (2-ethylhexyl) adipate, stearates such as butyl stearate or oleates such as butyl oleate, glycerol ethers or high molecular weight glycol ethers, glycerol esters, and p-toluenesulfonic acid esters.

Fixing agents contain polyvinylalkyl ethers, such as, for example, polyvinyl methyl ether, or ketones, such as benzophenone and ethylenebenzophenone, as a chemical base.

As solvents and diluents, in particular, water is used, if necessary, in a mixture with one or more of the above-mentioned organic, chemical solvents, respectively, diluents, emulsifying and dispersing agents.

Particularly effective wood protection is achieved by industrial impregnation, for example, using a vacuum, double vacuum or a method under pressure.

At the same time, the combinations of active substances according to the invention can be used to protect against fouling of objects, in particular such as ship hulls, sieves, nets, building structures, port berths and signaling devices that come into contact with sea or ballast water.

Fouling with settled Oligochaete, such as calcareous tubuli, as well as shells and species of the Ledamorpha group (weft shells), such as various species of Lepas and Scalpellum, or species of the Balanomorpha group (smallpox), such as Balanus- or Pollicipes-Species, increases friction resistance ships, as a result, leads to increased energy costs and, in addition, as a result of prolonged stay in dry docks to increase operating costs.

Along with algae fouling, such as Ectocarpus sp. And Ceramium sp., Fouling by settled entomostracic groups, which are united under the name Cirripedia (antennae crayfish), is of particular importance.

Surprisingly, it has been found that combinations of active substances according to the invention exhibit a very good antifouling effect.

When using combinations of active substances according to the invention, the concentration of compounds containing heavy metals can be neglected or significantly reduced, such as, for example, bis (trialkyltin) sulfides, tri-n-butyltin taurate, tri-n-butyltin chloride, copper oxide (I), triethyltin chloride, tri-n-butyl (2-phenyl-4-chlorophenoxy) tin, tributyltin oxide, molybdenum disulfide, arsenic monoxide, polymeric butyl titanate, phenyl (bis-pyridine) bismuth chloride, tri-n-butyltin ethylene bis-manganese zinc dimethyl dithiocarb at, zinc ethylene bis thiocarbamate, zinc and copper salts of 2-pyridinethiol-1-oxide, bis dimethyldithiocarbamoyl zinc ethylene bis thiocarbamate, zinc oxide, copper (I) ethylene bis dithiocarbamate, copper thiocyanate and copper naphthenate tributyltin halides.

Ready-to-use anti-fouling paints may optionally also contain other active substances, preferably algaecides, fungicides, herbicides, molluscicides, respectively, other anti-fouling, active substances.

The following are preferably suitable as a partner in the combination of anti-fouling agents according to the invention:

algaecides such as 2-tert-butylamino-4-cyclopropylamino-6-methylthio-1,3,5-triazine, dichlorophene, diuron, endotal, fentinacetate, isoproturon, metabenzothiazuron, oxyfluorfen, quinoclamine or terbutrin;

fungicides, such as benzo [b] thiophenecarboxylic acid cyclohexylamide SS-dioxide, dichlorofluanide, fluorofolpet, 3-iodo-2-propynylbutylcarbamate, tolylfluanide and azoles, such as azaconazoles, ciproconazoles, epoxiconazoles, azone azone;

molluscicides such as fentin acetate, metaldehyde, methiocarb, niclosamide, thiodicarb and trimethacarb,

or conventional anti-fouling active substances, such as 4,5-dichloro-2-octyl-4-isothiazolin-3-one, diiodomethyl-para-trilsulfone, 2- (N, N-dimethylthiocarbamoylthio) -5-nitrothiazyl, potassium, copper, sodium and zinc salts of 2-pyridinethiol-1-oxide, pyridinitripenylborane, tetrabutyldistannoxane, 2,3,5,6-tetrachloro-4- (methylsulfonyl) pyridine, 2,4,5,6-tetrachloroisophthalonitrile, tetramethylthiuramdisulfide and 2,4,6 trichlorophenylmaleinimide.

Used anti-fouling agents contain the active substance according to the invention with a concentration of from 0.001 to 50 wt.%, Preferably from 0.01 to 20 wt.%.

Antifouling agents according to the invention also contain conventional components, as described, for example, in Ungerer, Chem. Ind., 1985, 37, 730-732, or Williams, Antifouling Marine Coatings, Noyes, Park Ridge, 1973.

Gluing and coating materials contain, along with algicidal, fungicidal, molluscicidal and insecticidal active substances, in particular binders.

Examples of commonly used binders are polyvinyl chloride in a solvent system, chlorinated rubber in a solvent system, acrylic resins in a solvent system, especially in an aqueous system, vinyl chloride / vinyl acetate copolymer systems in the form of aqueous dispersions or in the form of organic solvent systems, butadiene-styrene-acrylonitrile rubbers drying oils such as linseed oil, ester resins or modified solid resins in combination with tar or bitumen, asphalt, as well as epoxy compounds, Small quantities of chlorine rubber, chlorinated polypropylene and vinyl resins.

If necessary, paints and varnishes also contain inorganic pigments, organic pigments or dyes, which are preferably insoluble in sea water. Further, paint and varnish materials may contain colophonium to create the possibility of controlled release of active substances. In addition, paints and varnishes may contain softeners, modifying agents that affect rheological properties, as well as other conventional components. And in a self-polishing anti-fouling system, the active substances according to the invention or the above mixtures can be used.

Combinations of active substances are also suitable for controlling animal pests, especially insects, arachnids and ticks that live in enclosed spaces, such as apartments, factory floors, institutions, car cabs and others. They are used to control these pests individually or in combination with other active or auxiliary substances in insecticidal products for the household. They are effective against sensitive and resistant species and at all stages of development. These pests include the following:

from the order Scorpionidea, for example, Buthus occitanus;

from the order Acarina, for example, Argas persicus, Argas reflexus, Bryobia ssp., Dermanyssus gallinae, Glyciphagus domesticus, Ornithodorus moubat, Rhipicephalus sanguineus, Trombicula alfreddugesi, Neutrombicula autumnalis, Dermatago

from the order Araneae, for example, Aviculariidae, Araneidae;

from the order Opiliones, for example, Pseudoscorpiones chelifer, Pseudoscorpiones cheiridium, Opiliones phalangium;

from the order Isopoda, for example, Oniscus asellus, Porcellio scaber;

from the order of Diplopoda, for example, Blaniulus guttulatus, Polydesmus spp .;

from the order Chilopoda, for example, Geophilus spp .;

from the order Zygentoma, for example, Ctenolepisma spp., Lepisma saccharina, Lepismodes inquilinus;

from the order Blattaria, e.g. Blatta orientalies, Blattella germanica, Blatella asahinai, Leucophaea maderae, Panchlora spp., Parcoblatta spp., Periplaneta australasiae, Periplaneta americana, Periplaneta brunnea, Periplaneta fuligalpa,

from the order Saltatoria, for example, Acheta domesticus;

from the order Dermaptera, for example, Forficula auricularia;

from the order Isoptera, for example, Kalotermes spp., Reticulitermes spp .;

from the order Psocoptera, for example, Lepinatus spp., Liposcelis spp .;

from the Coleptera order, e.g. Anthrenus spp., Attagenus spp., Dermestes spp., Latheticus oryzae, Necrobia spp., Ptinus spp., Rhizopertha dominica, Sitophilus granarius, Sitophilus oryzae, Sitophilus zeamais, Stegob;

from the order Diptera, for example, Aedes aegypti, Aedes albopictus, Aedes ta seniorhynchus, Anopheles spp., Calliphora erythrocephala, Chrysozona pluvialis, Culex quinquefasciatus, Culex pipiens, Culex tarsalis, Drosophia coloma pica musculoma spp. , Simulium spp., Stomoxys calcitrans, Tipula paludosa;

from the order Lepidoptera, for example, Achroia grisella, Galleria mellonella, Plodia interpunctella, Tinea cloacella, Tinea pellionella, Tineola bisselliella;

from the order Siphonaptera, for example, Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, Tunga penetrans, Xenopsylla cheopis;

from the order Hymenoptera, e.g. Camponotus herculeanus, Lasius fuliginosus, Lasius niger, Lasius umbratus, Monomorium pharaonis, Paravespula spp., Tetramorium caespitum;

from the order Anoplura, for example, Pediculus humanus capitis, Pediculus humanus corporis, Phthirus pubis;

from the order Heteroptera, for example, Cimex hemipterus, Cimex lectularius, Rhodinus prolixus, Triatoma infestans.

The application is carried out in the form of aerosols, spraying means that are not pressurized, for example, sprays for spraying with pumps and spraying machines for fogging, humidifiers, in the form of foam, in the form of gels, in the form of evaporation products with plates for evaporation from cellulose or plastic, in the form of liquid evaporators, gel and membrane evaporators, in the form of propeller evaporators, non-energized evaporation systems, respectively, in the form of passive evaporation systems, moth paper, bags for moths and gels for moths, in the form of granules and dust, in the form of loose bait and stations with bait.

According to the invention, all plants or parts of plants can be treated. By this, plants are understood to mean all plants and plant populations, both desirable and undesirable wild or cultivated plants (including naturally occurring cultivated plants). Cultivated plants are plants obtained by conventional methods of cultivation and cultivation or biotechnological and gene-technological methods, or by combinations of these methods, including transgenic plants and including plant varieties protected or not protected by the right to protect varieties. By plant parts is meant all the soil and underground parts and organs of plants located above the surface of the soil, such as seedlings, leaves, flowers and roots, for example, leaves, needles, stems, trunks, flowers, fruit bodies, fruits and seeds, and roots, tubers and roots. Parts of the plants include the crop, as well as vegetative and generative propagation material, for example seedlings (cuttings), tubers, roots, cuttings and seeds.

The treatment of plants and plant parts according to the invention with the active substances according to the invention occurs upon direct exposure to or on the environment, the living space or the space where the storage takes place, by conventional processing methods, for example by dipping, spraying, evaporation, fogging, sprinkling, brushing and in the case of planting material, especially seeds, in addition, single-layer or multi-layer coating.

As already mentioned above, in accordance with the invention, all plants and their parts can be treated. In one preferred embodiment, wild plants or plant species and plant varieties obtained by conventional biological cultivation methods, such as cross-breeding or protoplast fusion, as well as parts of plants, are treated. In another preferred embodiment, transgenic plants and plant varieties that are obtained by transgenic methods are processed, if necessary, in combination with conventional methods (genetically modified organisms) and parts thereof. The concept of "parts", respectively, "parts of plants" is explained above.

Commercial plants or plant varieties used are particularly preferably treated in accordance with the invention.

Depending on the type of plants, respectively, the variety of plants, its location and growth conditions (soil, climate, growing season, nutrition) as a result of processing in accordance with the invention, superadditive (“synergistic”) effects can be observed. So, for example, it is possible to reduce the amount of substances used and / or to expand the spectrum of action, and / or to increase the action of substances and means used according to the invention, to improve plant growth, increased tolerance to high or low temperatures, increased tolerance to lack of moisture or the salt content in water, respectively in the soil, increased productivity during flowering, easier harvesting, faster ripening, higher yield, higher quality and / or higher nutritional value ость yield of crop products, better shelf life and / or better processability of crop products that go beyond the expected effects.

Preferred transgenic (gene-derived) plants, respectively plant varieties that should be processed according to the invention, include all plants that received genetic material when modified by gene technology, which gave these plants particularly preferred valuable properties ("Traits"). Examples of such properties are better plant growth, increased tolerance to high or low temperatures, increased tolerance to lack of moisture or to the salt content in water, respectively in the soil, increased productivity during flowering, easier harvesting, faster ripening, higher yield, higher quality and / or higher nutritional value of crop products, better shelf life and / or better processability of crop products. Other and particularly preferred examples of such properties are increased plant resistance to animal pests and microbes, such as insects, mites, plant pathogens, bacteria and / or viruses, as well as increased plant tolerance to certain herbicidal active substances. As examples of transgenic plants, it is particularly preferable to mention important cultivated plants such as cereals (wheat, rice), corn, rice, soybeans, potatoes, cotton, canola, as well as fruit plants (with fruits of apples, pears, citrus fruits and grapes), moreover, corn, soy, potatoes, cotton and rapeseed are particularly preferred. As properties (Traits), they particularly prefer the increased resistance of plants to insects due to toxins formed in plants, especially those created using genetic material from Bacillus Thuringiensis (for example, using the genes CryIA (a), CryIA (b), CryIA (c) CryIIA, CryIIIA, CryIIIB2, Cry9c, Cry2Ab, Cry3Bb, and CryIF, as well as combinations thereof) in plants (hereinafter “BT.plants”). As properties ("Traits"), further increased plant tolerance to certain herbicidal active substances, for example imidazolines, sulfonylureas, glyphosates or phosphinotricin (for example, "PAT" gene), is especially appreciated. Genes that provide the desired properties ("Traits") can be found in transgenic plants and in combinations with each other. Examples of “BT. Plants” include corn varieties, cotton varieties, soybean varieties and potato varieties, which are sold under the trademarks YIELD GARD® (eg, corn, cotton, soy), Knockout® (eg, corn), StarLink® (e.g. corn), Bollgard® (cotton), Nucotn® (cotton), and NewLeaf® (potatoes). Examples of herbicide-tolerant plants include maize varieties, cotton varieties and soybean varieties sold under the trademarks Roundup Ready® (glyphosate tolerance, e.g. corn, cotton, soybean), Liberty Link® (phosphinotricin tolerance, e.g. rapeseed), IMI® (imidazolinone tolerance) and STS® (sulfonylurea tolerance, e.g. corn). As herbicide-resistant (traditionally grown as herbicide-tolerant) plants, the varieties supplied under the name Clearfield® (e.g. corn) should also be mentioned. It is clear that these statements are true for plant varieties that will be created in the future, respectively, which in the future will go on the market with these or in the future created genetic properties ("Traits").

These plants can be particularly preferably treated in accordance with the invention with mixtures of active substances according to the invention. The preferred ranges for the mixtures of the ratios given above are also valid for the treatment of these plants. Especially preferred is the treatment of plants with mixtures specifically provided in this text.

A good insecticidal and acaricidal effect of the combinations of active substances according to the invention is evident from the following examples. While individual active substances exhibit a weak effect, combinations exhibit an effect that exceeds a simple sum of effects.

A synergistic effect is present in insecticides and acaricides always if the effect of the combination of active substances exceeds the sum of the effects of separately applied active substances.

The expected effect of the action of a given combination of two active substances can, according to S.R. Colby, Weeds, 15, (1967), 20-22, be calculated as follows:

if X means the degree of devitalization (killing) in%, calculated in relation to the untreated control, when using the active substance A in an amount of m (g / ha) or with a concentration of m (million parts),

Y means the degree of devitalization in%, calculated in relation to the untreated control, when using active substance B in an amount of n (g / ha) or with a concentration of n (ppm),

E means the degree of devitalization in%, calculated in relation to the untreated control, when using the active substances A and B in quantities of m and n (g / ha) or with a concentration of m and n (million parts),

we get

If the actual degree of devitalization is greater than the calculated, then this means that the combination in its devitalization is super-additive, that is, there is a synergistic effect. In this case, the really observed degree of devitalization should be greater than the value calculated for the expected degree of devitalization (E) calculated using the above formula.

After the selected time, devitalization is determined in%. Moreover, 100% means that all animals are euthanized; 0% means that no animals have been euthanized.

Application examples

Example A

Aphis gossypii test

Solvent: 3 parts by weight of dimethylformamide.

Emulsifier: 1 part by weight of alkylaryl polyglycol ether.

To obtain a given composition of active substances, 1 weight part of the active substance is mixed with the indicated amounts of solvent and emulsifier and the concentrate is diluted with water to a predetermined concentration.

The leaves of cotton (Gossypium hirsutum), which were strongly attacked by lice of cotton leaves (Aphis gossypii), are dipped into the prepared composition of the active substance of the selected concentration.

After a selected period of time, devitalization (killing) in% is determined. Moreover, 100% means that all lice of the leaves are euthanized; 0% means that not one leaf louse has been euthanized. The resulting devitalization values are calculated using the Colby formula.

In this test, for example, the following combination of active substances according to this invention showed synergistically enhanced efficacy compared to active substances that were used separately.

Example B

Myzus test

Solvent: 3 parts by weight of dimethylformamide. Emulsifier: 1 part by weight of alkylaryl polyglycol ether.

To obtain a given composition of active substances, 1 weight part of the active substance is mixed with the indicated amounts of solvent and emulsifier and the concentrate is diluted with water to a predetermined concentration.

Leaves of cabbage (Brassica oleracea), which were strongly attacked by lice of peach leaves (Myzus persicae), are dipped into the prepared composition of the active substance of the selected concentration.

After a selected period of time, devitalization (killing) in% is determined. Moreover, 100% means that all pests are euthanized; 0% means that no pests have been euthanized. The resulting devitalization values are calculated using the Colby formula.

In this test, for example, the following combination of active substances according to this invention showed synergistically enhanced efficacy compared to active substances that were used separately.

Example B

Boundary concentration test / soil insects - transgenic plant treatment

Test insect: Diabrotica balteata - soil larvae.

Solvent: 7 parts by weight of acetone.

Emulsifier: 1 part by weight of alkylaryl polyglycol ether.

To obtain a given composition of active substances, 1 part by weight of the active substance is mixed with a specified amount of solvent, a specified amount of emulsifier is added, and the concentrate is diluted with water to a predetermined concentration.

The resulting solution of the active substance is poured onto the soil. In this case, the concentration of the active substance in the prepared solution practically does not play a role, the determining factor is the weight amount of the active substance per unit volume of soil, which is given in million parts (mg / l). The soil is placed in 0.25 L pots and left at 20 ° C.

Immediately after placing the soil in each pot, 5 nibbled corn kernels of the YIELD GUARD variety (trademark of Monsanto, USA) are laid. After 2 days, the appropriate test insects are placed in the treated soil. After another 7 days, the effectiveness of the active substance is determined when counting the sprouted corn plants (1 plant = 20% efficiency).

Example D

Heliothis virescens - test - treatment of transgenic plants

Solvent: 7 parts by weight of acetone.

Emulsifier: 1 part by weight of alkylaryl polyglycol ether.

To obtain a given composition of active substances, 1 part by weight of the active substance is mixed with the indicated amounts of solvent and emulsifier and the concentrate is diluted with water to a predetermined concentration.

Roundup Ready soybean seedlings (Glycine max) (trademark of Monsanto, USA) are dipped into the prepared solution of the active substance of a given concentration and placed on still moist leaves of the caterpillars of the tobacco buds Heliothis virescens.

After a specified time, the devitalization of insects is determined.

Tables 3-9 show the results of biological tests of known compounds and agents according to the invention. The preparation of the tested means, the treatment of plants affected by pests and the determination of the degree of pest devitalization were carried out as shown for examples A and B.

In the preparation of the test agents, the following were used.

Solvent: 7 parts by weight of dimethylformamide.

Emulsifier: 2 parts by weight of alkylaryl polyglycol ether per one part by weight of the active component.

Example D

Tetranychus test (phosphate resistance)

Solvent: 7 parts by weight of dimethylformamide.

Emulsifier: 2 parts by weight of alkylaryl polyglycol ether

To obtain a given composition of active substances, 1 weight part of the active substance is mixed with the indicated amounts of solvent and emulsifier and the concentrate is diluted with water to a predetermined concentration.

Bean plants (Phaseolus vulgaris), which were heavily attacked by a spider mite (Tetranychus urticae), are dipped into the prepared composition of the active substance of the selected concentration.

After a selected period of time, devitalization (killing) in% is determined. Moreover, 100% means that all pests are euthanized; 0% means that no pests have been euthanized.

In this test, for example, the following combinations of active substances according to this invention showed synergistically enhanced efficacy compared to active substances that were used separately.

Claims (3)

1. A means for controlling insects and acarides, containing a mixture of (a) compounds of formula (I)

in which X is (C ₁ -C ₄ ) -alkyl; W, Y and Z are, independently of one another, hydrogen or (C ₁ -C ₄ ) -alkyl; A and B, together with the carbon atom to which they are attached, mean saturated, once substituted by (C ₁ -C ₄ ) alkoxy (C ₃ -C ₆ ) cycloalkyl; D is hydrogen; G means hydrogen or a group

where M is oxygen; R ² means (C ₁ -C ₈ ) alkyl and (b) one of the following compounds: acrinatrin, cypermethrin, alpha-cypermethrin, zeta-cypermethrin, cyfluthrin, beta-cyfluthrin, deltamethrin, lambda-cygalothrin, fenpropatrin and bifentrin, with components (a) and (b) taken in a weight ratio of 25: 1 to 1: 1. 2. The tool according to claim 1, containing a compound of formula (I), in which X, W, Y and Z are methyl, A and B, together with the carbon atom to which they are attached, mean saturated, once substituted by a methoxy group C ₆ -cycloalkyl, D and G are hydrogen. 3. The tool according to claim 1, containing as component (a) the compound (1-4) of the formula

where X is methyl; W is hydrogen; Y is methyl, in particular at position 5; Z is hydrogen; R is methoxy; G means a group