RU2019108902A - Композиции и способы для модулирования микрофлоры желудочно-кишечного тракта у животного из семейства собачьих - Google Patents
Композиции и способы для модулирования микрофлоры желудочно-кишечного тракта у животного из семейства собачьих Download PDFInfo
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- RU2019108902A RU2019108902A RU2019108902A RU2019108902A RU2019108902A RU 2019108902 A RU2019108902 A RU 2019108902A RU 2019108902 A RU2019108902 A RU 2019108902A RU 2019108902 A RU2019108902 A RU 2019108902A RU 2019108902 A RU2019108902 A RU 2019108902A
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- Russia
- Prior art keywords
- food composition
- pet food
- canine
- microflora
- probiotic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 10
- 244000005706 microflora Species 0.000 title claims 6
- 210000001035 gastrointestinal tract Anatomy 0.000 title claims 2
- 235000013305 food Nutrition 0.000 claims 9
- 241000282465 Canis Species 0.000 claims 7
- 239000006041 probiotic Substances 0.000 claims 5
- 230000000529 probiotic effect Effects 0.000 claims 5
- 235000018291 probiotics Nutrition 0.000 claims 5
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 241000192125 Firmicutes Species 0.000 claims 2
- 241000186870 Lactobacillus ruminis Species 0.000 claims 2
- 208000023178 Musculoskeletal disease Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 235000014633 carbohydrates Nutrition 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000606125 Bacteroides Species 0.000 claims 1
- 241000605059 Bacteroidetes Species 0.000 claims 1
- 241000194002 Blautia hansenii Species 0.000 claims 1
- 241000193163 Clostridioides difficile Species 0.000 claims 1
- 241000193171 Clostridium butyricum Species 0.000 claims 1
- 241000193468 Clostridium perfringens Species 0.000 claims 1
- 241000194031 Enterococcus faecium Species 0.000 claims 1
- 241000605980 Faecalibacterium prausnitzii Species 0.000 claims 1
- 241000037075 Intestinibacter bartlettii Species 0.000 claims 1
- 241000904817 Lachnospiraceae bacterium Species 0.000 claims 1
- 240000001046 Lactobacillus acidophilus Species 0.000 claims 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims 1
- 241000192031 Ruminococcus Species 0.000 claims 1
- 241000134861 Ruminococcus sp. Species 0.000 claims 1
- 241001473878 Streptococcus infantarius Species 0.000 claims 1
- 241001678097 Turicibacter sanguinis Species 0.000 claims 1
- 241000030487 [Clostridium] hiranonis Species 0.000 claims 1
- 235000013325 dietary fiber Nutrition 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- 235000019197 fats Nutrition 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims 1
- 235000013406 prebiotics Nutrition 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Birds (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Claims (17)
1. Способ модулирования микрофлоры желудочно-кишечного тракта у животного из семейства собачьих, включающий:
введение животному из семейства собачьих композиции корма для домашних животных, содержащей от приблизительно 25% до приблизительно 60% белка, от приблизительно 5% до приблизительно 30% углеводов, жиры и пищевые волокна;
причем после введения соотношение бактероидов (Bacteroidetes) и фирмикутов (Firmicutes) (B/F) у животного из семейства собачьих составляет менее 0,8.
2. Способ по п. 1, в котором композиция корма для домашних животных содержит первый пробиотик, который снижает микрофлору с преобладанием бактероидов у животного из семейства собачьих.
3. Способ по п. 2, в котором композиция корма для домашних животных содержит второй пробиотик, который увеличивает микрофлору с преобладанием фирмикутов.
4. Способ по п. 1, в котором композиция корма для домашних животных содержит пробиотик, который увеличивает микрофлору с преобладанием фирмикутов у животного из семейства собачьих.
5. Способ по п. 4, в котором пробиотик вводят отдельно от композиции корма для домашних животных.
6. Способ по п. 4, в котором пробиотик добавляют в композицию корма для домашних животных перед введением.
7. Способ по п. 1, дополнительно включающий идентификацию животного из семейства собачьих, имеющего диабет, ожирение, воспалительное заболевание, сердечно-сосудистое заболевание, нарушение обмена веществ, мышечно-скелетное нарушение или рак.
8. Способ по п. 1, в котором модулирование микрофлоры желудочно-кишечного тракта животного из семейства собачьих является частью лечения диабета, ожирения, воспалительного заболевания, сердечно-сосудистого заболевания, нарушения обмена веществ, мышечно-скелетного нарушения или рака.
9. Способ по п. 1, в котором соотношение бактероидов и фирмикутов (B/F) у животного из семейства собачьих составляет менее 0,7.
10. Способ по п. 1, в котором композиция корма для домашних животных содержит от приблизительно 45% до приблизительно 60% белка.
11. Способ по п. 1, в котором композиция корма для домашних животных содержит от приблизительно 10% до приблизительно 20% углеводов.
12. Способ по п. 1, в котором композиция корма для домашних животных содержит пребиотик.
13. Способ по п. 1, в котором введение осуществляют на регулярной основе.
14. Способ по п. 1, в котором соотношение B/F рассчитывают на основе присутствия Streptococcus infantarius, Ruminococcus sp., [Clostridium] hiranonis, Clostridium perfringens, Enterococcus faecium, [Clostridium] bartlettii, [Clostridium] difficile, [Ruminococcus] gnavus, Lachnospiraceae bacterium, Blautia hansenii, [Ruminococcus] obeum, Faecalibacterium prausnitzii, Clostridium butyricum, Lactobacillus ruminis, Turicibacter sanguinis и Lactobacillus acidophilus типа фирмикутов и Bacteroides coprocola, Parabacteroides merdae, Bacteroides coprophilus, Prevotella copri и Bacteroides sp. типа бактероидов.
15. Способ по п. 1, в котором после введения количество Lactobacillus ruminis уменьшается на 25%.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662382923P | 2016-09-02 | 2016-09-02 | |
| US62/382,923 | 2016-09-02 | ||
| PCT/IB2017/055140 WO2018042304A1 (en) | 2016-09-02 | 2017-08-25 | Compositions and methods for modulating gastrointestinal microflora in a canine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2019108902A true RU2019108902A (ru) | 2020-10-02 |
| RU2019108902A3 RU2019108902A3 (ru) | 2020-10-14 |
| RU2742512C2 RU2742512C2 (ru) | 2021-02-08 |
Family
ID=59923495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019108902A RU2742512C2 (ru) | 2016-09-02 | 2017-08-25 | Композиции и способы для модулирования микрофлоры желудочно-кишечного тракта у животного из семейства собачьих |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10405563B2 (ru) |
| EP (1) | EP3506767B1 (ru) |
| JP (1) | JP2019528698A (ru) |
| CN (1) | CN109640688A (ru) |
| AU (1) | AU2017318650B2 (ru) |
| BR (1) | BR112019003410A2 (ru) |
| CA (1) | CA3033565A1 (ru) |
| ES (1) | ES3031832T3 (ru) |
| MX (1) | MX385747B (ru) |
| RU (1) | RU2742512C2 (ru) |
| WO (1) | WO2018042304A1 (ru) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12053495B2 (en) | 2017-12-11 | 2024-08-06 | Vedanta Biosciences, Inc. | Compositions and methods for suppressing pathogenic organisms |
| JP7408539B2 (ja) * | 2018-03-29 | 2024-01-05 | 森永乳業株式会社 | プロバイオティクスを用いた肥満の治療、体脂肪減少用組成物、及びウエスト周囲径低減用組成物 |
| EP3892740B1 (en) | 2018-09-13 | 2025-02-26 | Gnubiotics Sciences SA | Microbiome markers and uses thereof |
| CN113227402A (zh) * | 2018-12-27 | 2021-08-06 | 雀巢产品有限公司 | 用于诊断和治疗犬科动物的退行性二尖瓣疾病的组合物和方法 |
| WO2020150672A2 (en) * | 2019-01-18 | 2020-07-23 | Mars, Incorporated | Methods and compositions for treating intestinal dysbiosis |
| WO2020154523A2 (en) | 2019-01-23 | 2020-07-30 | Mars, Incorporated | Methods and compositions for treating intestinal disorder |
| EP3952864A4 (en) | 2019-03-08 | 2023-05-10 | The Regents of the University of California | COMPOSITIONS AND METHODS FOR MODULATION OF LIPID AND STEROID METABOLISM |
| WO2021030198A1 (en) * | 2019-08-09 | 2021-02-18 | Vedanta Biosciences, Inc. | Compositions and methods for suppressing pathogenic organisms |
| US11675846B2 (en) * | 2019-09-10 | 2023-06-13 | Allfin Inc. | Nutritional balance providing system based on pet health information |
| GB201914385D0 (en) * | 2019-10-04 | 2019-11-20 | Mars Inc | Microbiome Interventions |
| WO2021127701A1 (en) * | 2019-12-19 | 2021-06-24 | Hill's Pet Nutrition, Inc. | Pet food compositions |
| CN112401071B (zh) * | 2020-11-19 | 2021-08-27 | 山东龙昌动物保健品有限公司 | 一种胆汁酸复合菌剂在用于制备肉羊饲料添加剂中的应用 |
| WO2023244712A1 (en) * | 2022-06-15 | 2023-12-21 | Hill's Pet Nutrition, Inc. | Pet food compositions and method for reducing metabolites associated with protein putrefaction in a feline |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410063B1 (en) | 2000-06-13 | 2002-06-25 | Hill's Pet Nutrition, Inc. | Composition and method |
| US20030138547A1 (en) * | 2002-01-22 | 2003-07-24 | Mars, Incorporated | Weight management system for animals |
| JP4600969B2 (ja) | 2002-01-22 | 2010-12-22 | マース インコーポレーテッド | 肥満動物のための体重管理システム |
| ES2318307T5 (es) * | 2003-06-03 | 2013-03-06 | Hill's Pet Nutrition, Inc. | Composición alimentaria para gatos con mucha proteína y pocos carbohidratos que comprende fibra no fermentable |
| WO2007126990A2 (en) * | 2006-03-29 | 2007-11-08 | Nestec S.A. | Dietary supplements containing probiotics |
| US9386793B2 (en) | 2010-08-20 | 2016-07-12 | New York University | Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota |
| WO2012087511A1 (en) * | 2010-12-23 | 2012-06-28 | Hill's Pet Nutrition, Inc. | Pet food compositions and methods for weight loss and maintenance |
| WO2013032744A2 (en) | 2011-08-17 | 2013-03-07 | Nume Health, Llc | Composition and use of a formulation to increase the ratio of gastrointestinal microbiota in phylum bacteriodites to microbiota of firmuctes phylum |
| CN102524591B (zh) * | 2012-02-14 | 2013-06-05 | 长沙绿叶生物科技有限公司 | 一种肥胖犬用保健日粮 |
| EP2909335B1 (en) | 2012-10-17 | 2018-05-30 | Institut National de la Recherche Agronomique | Prognostic of diet impact on obesity-related co-morbidities |
-
2017
- 2017-08-25 CN CN201780051022.2A patent/CN109640688A/zh active Pending
- 2017-08-25 US US15/686,893 patent/US10405563B2/en active Active
- 2017-08-25 ES ES17771588T patent/ES3031832T3/es active Active
- 2017-08-25 JP JP2019511516A patent/JP2019528698A/ja active Pending
- 2017-08-25 EP EP17771588.5A patent/EP3506767B1/en active Active
- 2017-08-25 MX MX2019001903A patent/MX385747B/es unknown
- 2017-08-25 WO PCT/IB2017/055140 patent/WO2018042304A1/en not_active Ceased
- 2017-08-25 AU AU2017318650A patent/AU2017318650B2/en active Active
- 2017-08-25 CA CA3033565A patent/CA3033565A1/en active Pending
- 2017-08-25 BR BR112019003410-2A patent/BR112019003410A2/pt not_active Application Discontinuation
- 2017-08-25 RU RU2019108902A patent/RU2742512C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3506767A1 (en) | 2019-07-10 |
| CN109640688A (zh) | 2019-04-16 |
| US10405563B2 (en) | 2019-09-10 |
| CA3033565A1 (en) | 2018-03-08 |
| ES3031832T3 (en) | 2025-07-11 |
| US20180064140A1 (en) | 2018-03-08 |
| RU2019108902A3 (ru) | 2020-10-14 |
| JP2019528698A (ja) | 2019-10-17 |
| AU2017318650A1 (en) | 2019-02-14 |
| MX2019001903A (es) | 2019-07-15 |
| MX385747B (es) | 2025-03-18 |
| EP3506767B1 (en) | 2025-05-28 |
| BR112019003410A2 (pt) | 2019-05-21 |
| AU2017318650B2 (en) | 2021-12-09 |
| RU2742512C2 (ru) | 2021-02-08 |
| WO2018042304A1 (en) | 2018-03-08 |
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