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RU2018102283A - Устройства и способы доставки гемостатических порошков - Google Patents

Устройства и способы доставки гемостатических порошков Download PDF

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Publication number
RU2018102283A
RU2018102283A RU2018102283A RU2018102283A RU2018102283A RU 2018102283 A RU2018102283 A RU 2018102283A RU 2018102283 A RU2018102283 A RU 2018102283A RU 2018102283 A RU2018102283 A RU 2018102283A RU 2018102283 A RU2018102283 A RU 2018102283A
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Prior art keywords
powder
extrusion
filter
tank
air pump
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RU2018102283A
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English (en)
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RU2714944C2 (ru
RU2018102283A3 (ru
Inventor
Джон ГУДМЭН
Алекс В. КИТУРКЕС
Джаред ШНАЙДЕР
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Этикон, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/008—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised by squeezing, e.g. using a flexible bottle or a bulb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M13/00—Insufflators for therapeutic or disinfectant purposes, i.e. devices for blowing a gas, powder or vapour into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/10—General characteristics of the apparatus with powered movement mechanisms

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgery (AREA)
  • Surgical Instruments (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)

Claims (24)

1. Устройство для выдавливания порошка, содержащее
a) удлиненный полый резервуар, имеющий ручной воздушный насос, прикрепленный к резервуару, и отверстие для выдавливания на дистальном конце указанного резервуара,
b) пористый фильтр, размещенный внутри резервуара с возможностью скольжения между указанным воздушным насосом и указанным отверстием для выдавливания;
c) пружину, размещенную внутри резервуара между воздушным насосом и фильтром;
причем порошок находится внутри резервуара между фильтром и отверстием для выдавливания и насос сообщается по текучей среде с отверстием для выдавливания через пористый фильтр и через порошок.
2. Устройство по п. 1, в котором указанный ручной воздушный насос содержит сильфон.
3. Устройство по п. 1, в котором указанный фильтр содержит взаимно соединенные поры или каналы, имеющие размер, по существу предотвращающий прохождение порошка через фильтр.
4. Устройство по п. 1, в котором указанный пористый фильтр прикреплен к плунжеру, размещенному внутри резервуара с возможностью скольжения между указанным фильтром и указанным ручным воздушным насосом, а полая канюля для выдавливания прикреплена к указанному отверстию для выдавливания и проходит из устройства дистально, причем указанная канюля для выдавливания находится в сообщении по текучей среде с указанным насосом.
5. Устройство по п. 4, в котором указанный плунжер имеет удлиненный шток, проходящий из указанного плунжера в направлении проксимального конца, и указанная пружина по меньшей мере частично опирается на указанный шток.
6. Устройство по п. 4, дополнительно содержащее
a) ловушку для порошка, расположенную между отверстием для выдавливания и канюлей для выдавливания, причем ловушка для порошка содержит
i) извилистый канал для порошка, который имеет входное отверстие, открытое в резервуар, и выходное отверстие, открытое в канюлю для выдавливания.
7. Устройство по п. 6, дополнительно содержащее блокирующий элемент внутри резервуара, причем указанная ловушка для порошка выполнена с возможностью поворота вокруг резервуара из первого положения во второе положение и в первом положении входное отверстие заблокировано блокирующим элементом, а во втором положении входное отверстие не заблокировано блокирующим элементом.
8. Устройство по п. 6, в котором насос находится в сообщении по текучей среде с канюлей для выдавливания через резервуар, плунжер, пористый фильтр, порошок, входное отверстие, извилистый канал и выходное отверстие.
9. Устройство по п. 6, дополнительно содержащее зазор между плунжером и стенкой резервуара.
10. Устройство по п. 6, в котором плунжер имеет по меньшей мере одно отверстие, обеспечивающее сообщение по текучей среде между воздушным насосом и пористым фильтром.
11. Устройство по п. 6, в котором перед выдавливанием порошка пружина находится в несжатом состоянии.
12. Устройство по п. 6, в котором пружина сжимается в направлении дистального конца путем сжатия воздушного насоса.
13. Устройство по п. 6, в котором пористый фильтр продвигается внутри резервуара под действием пружины в направлении дистального конца.
14. Устройство по п. 1, в котором указанный порошок представляет собой гемостатический порошок.
15. Устройство по п. 1, в котором указанный порошок представляет собой порошок окисленной регенерированной целлюлозы (ОРЦ).
16. Устройство по п. 1, в котором количество порошка, выдавливаемого из устройства, по существу не зависит от ориентации устройства.
17. Устройство по п. 1, в котором количество порошка, выдавливаемого из устройства каждым отдельным выдавливанием в начале доставки порошка, отличается не более чем на 10% от количества порошка, выдавливаемого из устройства каждым отдельным выдавливанием в конце доставки порошка.
18. Устройство по п. 1, в котором пружина содержит упруго сжимаемую металлическую спираль, упруго сжимаемую полимерную спираль или упруго сжимаемый пеноматериал.
RU2018102283A 2015-06-24 2016-05-20 Устройства и способы доставки гемостатических порошков RU2714944C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562183916P 2015-06-24 2015-06-24
US62/183,916 2015-06-24
US15/092,712 2016-04-07
US15/092,712 US10507293B2 (en) 2015-06-24 2016-04-07 Hemostatic powder delivery devices and methods
PCT/US2016/033444 WO2016209442A1 (en) 2015-06-24 2016-05-20 Hemostatic powder delivery devices and methods

Related Child Applications (1)

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RU2020105860A Division RU2020105860A (ru) 2015-06-24 2016-05-20 Устройства и способы доставки гемостатических порошков

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RU2018102283A true RU2018102283A (ru) 2019-07-24
RU2018102283A3 RU2018102283A3 (ru) 2019-10-04
RU2714944C2 RU2714944C2 (ru) 2020-02-21

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RU2018102283A RU2714944C2 (ru) 2015-06-24 2016-05-20 Устройства и способы доставки гемостатических порошков

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US (3) US10507293B2 (ru)
EP (2) EP3313485B1 (ru)
JP (1) JP6746623B2 (ru)
CN (1) CN107801381B (ru)
AU (1) AU2016281539B2 (ru)
BR (1) BR112017027717B1 (ru)
CA (1) CA2990593C (ru)
ES (2) ES2819500T3 (ru)
MA (1) MA53993A (ru)
MX (1) MX2017016779A (ru)
PL (2) PL3785753T3 (ru)
RU (2) RU2020105860A (ru)
WO (1) WO2016209442A1 (ru)

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