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RU2016143874A - METHOD OF CONTINUOUS MONITORING OF ANALYTES IN BLOOD - Google Patents

METHOD OF CONTINUOUS MONITORING OF ANALYTES IN BLOOD Download PDF

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Publication number
RU2016143874A
RU2016143874A RU2016143874A RU2016143874A RU2016143874A RU 2016143874 A RU2016143874 A RU 2016143874A RU 2016143874 A RU2016143874 A RU 2016143874A RU 2016143874 A RU2016143874 A RU 2016143874A RU 2016143874 A RU2016143874 A RU 2016143874A
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RU
Russia
Prior art keywords
blood
analyte
tube
analytical
wall
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Application number
RU2016143874A
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Russian (ru)
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RU2016143874A3 (en
RU2672354C2 (en
Inventor
Юрий Владимирович Тарасов
Юрий Иванович Филиппов
Максим Дмитриевич БОЯРСКИЙ
Original Assignee
Байнари Хеликс Системс
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Priority to RU2016143874A priority Critical patent/RU2672354C2/en
Publication of RU2016143874A publication Critical patent/RU2016143874A/en
Publication of RU2016143874A3 publication Critical patent/RU2016143874A3/ru
Application granted granted Critical
Publication of RU2672354C2 publication Critical patent/RU2672354C2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Claims (6)

Способ непрерывного мониторинга концентрации аналита в крови с массой молекул 400 Дальтон и менее, содержащий шаги, на которыхA method for continuously monitoring the concentration of an analyte in a blood with a molecular weight of 400 Daltons or less, comprising the steps of в тело пациента имплантируют устройство мониторинга, содержащее полимерный корпус, соединенный с одной стороны по периметру с вводным концом полимерной трубки, а с другой стороны по периметру с отводящим концом полимерной трубки, мембрану трубчатой формы, размещенную соосно в корпусе в торцевых отверстиях корпуса и соединенную бесшовными соединениями с внутренней поверхностью вводного и отводного концов трубки с образованием протока для крови, причем полость между стенкой корпуса и мембраной является аналитическим резервуаром,a monitoring device is implanted into the patient’s body, containing a polymer case connected on one side along the perimeter to the inlet end of the polymer tube, and on the other hand along the perimeter to the outlet end of the polymer tube, a tubular membrane placed coaxially in the case in the housing end openings and connected seamlessly compounds with the inner surface of the inlet and outlet ends of the tube with the formation of a duct for blood, and the cavity between the wall of the body and the membrane is an analytical reservoir, соединяют вводный конец трубки со стенкой артериального сосуда для отвода части артериальной крови из сосуда к аналитическому резервуару иconnecting the lead end of the tube to the wall of the arterial vessel to divert part of the arterial blood from the vessel to the analytical reservoir and соединяют выводной конец трубки со стенкой венозного сосуда для отвода крови из аналитического резервуара, причем соединение с кровеносными сосудами осуществляют по принципу шунта,connecting the output end of the tube to the wall of the venous vessel to drain blood from the analytical reservoir, and the connection with the blood vessels is carried out according to the principle of a shunt, под действием разности концентраций аналита, растворенного в крови, и аналита в фильтрате в аналитическом резервуаре, через мембрану в аналитический резервуар отфильтровывается аналит,under the influence of the difference in the concentrations of the analyte dissolved in the blood and the analyte in the filtrate in the analytical tank, the analyte is filtered through the membrane into the analytical tank, посредством бесконтактного датчика непрерывно замеряют концентрацию аналита в крови и передают сигналы о концентрации аналита в крови на монитор.Using a non-contact sensor, the analyte concentration in the blood is continuously measured and signals about the analyte concentration in the blood are transmitted to the monitor.
RU2016143874A 2016-11-09 2016-11-09 Method for continuous monitoring of analyte content in blood RU2672354C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016143874A RU2672354C2 (en) 2016-11-09 2016-11-09 Method for continuous monitoring of analyte content in blood

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016143874A RU2672354C2 (en) 2016-11-09 2016-11-09 Method for continuous monitoring of analyte content in blood

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2013104340/15A Previously-Filed-Application RU2013104340A (en) 2013-02-04 2013-02-04 METHOD FOR FILTRATION ANALYTES IN BLOOD

Publications (3)

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RU2016143874A true RU2016143874A (en) 2018-05-10
RU2016143874A3 RU2016143874A3 (en) 2018-05-10
RU2672354C2 RU2672354C2 (en) 2018-11-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016143874A RU2672354C2 (en) 2016-11-09 2016-11-09 Method for continuous monitoring of analyte content in blood

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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579690B1 (en) * 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US8808515B2 (en) * 2007-01-31 2014-08-19 Abbott Diabetes Care Inc. Heterocyclic nitrogen containing polymers coated analyte monitoring device and methods of use
RU2444980C2 (en) * 2007-03-07 2012-03-20 Эко Терапьютикс, Инк. Transdermal system of analite monitoring and methods of analite detection

Also Published As

Publication number Publication date
RU2016143874A3 (en) 2018-05-10
RU2672354C2 (en) 2018-11-14

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20191110