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RU2015121346A - DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME - Google Patents

DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME Download PDF

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RU2015121346A
RU2015121346A RU2015121346A RU2015121346A RU2015121346A RU 2015121346 A RU2015121346 A RU 2015121346A RU 2015121346 A RU2015121346 A RU 2015121346A RU 2015121346 A RU2015121346 A RU 2015121346A RU 2015121346 A RU2015121346 A RU 2015121346A
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output
detector
wavefront
light source
eye
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RU2015121346A
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Russian (ru)
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Ян Чжоу
Брэдфорд ЧУ
Уилльям ШИ
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Клэрити Медикал Системз, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1015—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for wavefront analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00825—Methods or devices for eye surgery using laser for photodisruption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A61F2009/00846—Eyetracking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A61F2009/00848—Feedback systems based on wavefront
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A61F2009/00851—Optical coherence topography [OCT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00853—Laser thermal keratoplasty or radial keratotomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/0087—Lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872—Cornea
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00—Control; Monitoring or safety arrangements
    • F04C2270/04—Force
    • F04C2270/041—Controlled or regulated

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Eye Examination Apparatus (AREA)
  • Human Computer Interaction (AREA)
  • Radiology & Medical Imaging (AREA)
  • Microscoopes, Condenser (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement Of Optical Distance (AREA)
  • Optical Radar Systems And Details Thereof (AREA)

Abstract

1. Датчик волнового фронта, содержащий:источник 172 света, сконфигурированный для вывода светового пучка, чтобы освещать глаз субъекта;схему 715 приведения в действие источника света, связанную с источником света, сконфигурированную для вывода сигнала возбуждения источника света с первой частотой пульсации;позиционно-чувствительный детектор 122, имеющий множество детекторных элементов, сконфигурированных для вывода множества выходных сигналов детектора, указывающих уровень сигнала падающего света на каждом детекторном элементе;первый элемент 112 отклонения пучка, сконфигурированный для перехвата пучка волнового фронта, возвращенного от глаза субъекта, когда глаз субъекта подсвечивается источником света, и сконфигурированный для направления части волнового фронта от глаза субъекта через апертуру к детектору, где часть волнового фронта, направленного через апертуру, образует пятно на детекторе с амплитудой отклонения центроида пятна от опорной точки на детекторе, приближенно указываемой логометрической комбинацией уровней сигналов, при этом амплитуда отклонения указывает степень наклона или сходимости или расходимости части волнового фронта от плоской волны;схему 720 приведения в действие элемента отклонения пучка, связанную с первым элементом отклонения пучка, сконфигурированную для вывода сигнала управления элементом отклонения пучка, чтобы сканировать часть волнового фронта с частотой сканирования волнового фронта; имножество составных трансимпедансных усилителей фиг. 11, каждый из которых имеет вход, подсоединенный для приема одного из множества выходных сигналов детектора, и выход для обеспеченияA wavefront sensor, comprising: a light source 172 configured to output a light beam to illuminate a subject's eye; a light source driving circuit 715 associated with a light source configured to output a light source excitation signal with a first pulsation frequency; a sensitive detector 122 having a plurality of detector elements configured to output a plurality of detector outputs indicative of an incident light signal level at each detector element; first A beam deflection element 112 configured to intercept a wavefront beam returned from the subject’s eye when the subject’s eye is illuminated by a light source, and configured to direct a portion of the wavefront from the subject’s eye through the aperture to the detector, where a portion of the wavefront directed through the aperture forms a spot on the detector with the amplitude of the deviation of the spot centroid from the reference point on the detector, approximately indicated by a ratiometric combination of signal levels, while the deviation amplitude is indicated the degree of inclination or convergence or divergence of a part of the wavefront from the plane wave; a driving circuit 720 for the beam deflection element associated with the first beam deflection element configured to output a control signal of the beam deflection element to scan part of the wavefront with the wavefront scanning frequency; a plurality of composite transimpedance amplifiers of FIG. 11, each of which has an input connected to receive one of a plurality of detector output signals, and an output to provide

Claims (4)

1. Датчик волнового фронта, содержащий: 1. The wavefront sensor containing: источник 172 света, сконфигурированный для вывода светового пучка, чтобы освещать глаз субъекта; a light source 172 configured to output a light beam to illuminate the subject's eye; схему 715 приведения в действие источника света, связанную с источником света, сконфигурированную для вывода сигнала возбуждения источника света с первой частотой пульсации; a light source driving circuit 715 coupled to the light source configured to output a light source drive signal with a first ripple frequency; позиционно-чувствительный детектор 122, имеющий множество детекторных элементов, сконфигурированных для вывода множества выходных сигналов детектора, указывающих уровень сигнала падающего света на каждом детекторном элементе; a position sensitive detector 122 having a plurality of detector elements configured to output a plurality of detector outputs indicative of an incident light signal level at each detector element; первый элемент 112 отклонения пучка, сконфигурированный для перехвата пучка волнового фронта, возвращенного от глаза субъекта, когда глаз субъекта подсвечивается источником света, и сконфигурированный для направления части волнового фронта от глаза субъекта через апертуру к детектору, где часть волнового фронта, направленного через апертуру, образует пятно на детекторе с амплитудой отклонения центроида пятна от опорной точки на детекторе, приближенно указываемой логометрической комбинацией уровней сигналов, при этом амплитуда отклонения указывает степень наклона или сходимости или расходимости части волнового фронта от плоской волны; a first beam deflection element 112, configured to intercept a wavefront beam returned from the subject’s eye when the subject’s eye is illuminated by a light source, and configured to direct a portion of the wavefront from the subject’s eye through the aperture to the detector, where a portion of the wavefront directed through the aperture forms a spot on the detector with the amplitude of the deviation of the centroid of the spot from the reference point on the detector, approximately indicated by a ratiometric combination of signal levels, while the amplitude of the deviation Nia indicates the degree of tilt or convergence or divergence portion of the wavefront from a plane wave; схему 720 приведения в действие элемента отклонения пучка, связанную с первым элементом отклонения пучка, сконфигурированную для вывода сигнала управления элементом отклонения пучка, чтобы сканировать часть волнового фронта с частотой сканирования волнового фронта; иa beam deflection element driving circuit 720 associated with a first beam deflection element configured to output a control signal of the beam deflection element to scan a portion of the wavefront with a wavefront scanning frequency; and множество составных трансимпедансных усилителей фиг. 11, каждый из которых имеет вход, подсоединенный для приема одного из множества выходных сигналов детектора, и выход для обеспечения усиленного выходного сигнала детектора, причем выход каждого трансимпедансного усилителя синхронизирован по фазе с сигналом возбуждения источника света и сигналом управления элементом отклонения пучка.the plurality of composite transimpedance amplifiers of FIG. 11, each of which has an input connected to receive one of a plurality of detector output signals and an output to provide an amplified detector output signal, wherein the output of each transimpedance amplifier is phase locked to the light source drive signal and the beam deflection control signal. 2. Датчик волнового фронта по п. 1, причем каждый составной трансимпедансный усилитель содержит фильтр 1150 нижних частот для увеличения стабильности и уменьшения высокочастотного шума.2. The wavefront sensor according to claim 1, wherein each composite transimpedance amplifier comprises a low-pass filter 1150 to increase stability and reduce high-frequency noise. 3. Датчик волнового фронта по п. 2, причем фильтр нижних частот содержит: 3. The wavefront sensor according to claim 2, wherein the low-pass filter contains: первый операционный усилитель U2A, имеющий вход и выход; a first operational amplifier U2A having an input and an output; первый резистор R3 иfirst resistor R3 and первый конденсатор C3, причем первые резистор и конденсатор соединены последовательно между входом и выходом первого операционного усилителя. a first capacitor C3, wherein the first resistor and capacitor are connected in series between the input and output of the first operational amplifier. 4. Датчик волнового фронта по п. 3, причем составной трансимпедансный усилитель дополнительно содержит: 4. The wavefront sensor according to claim 3, wherein the composite transimpedance amplifier further comprises: второй операционный усилитель U1A, имеющий вход и выход, и a second operational amplifier U1A having an input and an output, and резистор R1 обратной связи, имеющий значение сопротивления обратной связи, связывающий выход первого операционного усилителя с входом второго операционного усилителя, причем амплитуда усиленного выходного сигнала детектора пропорциональна R1, и шум пропорционален квадратному корню из R1. feedback resistor R1 having a feedback resistance value connecting the output of the first operational amplifier with the input of the second operational amplifier, the amplitude of the amplified output signal of the detector being proportional to R1, and the noise proportional to the square root of R1.
RU2015121346A 2012-11-07 2013-11-06 DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME RU2015121346A (en)

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US201261723531P 2012-11-07 2012-11-07
US61/723,531 2012-11-07
PCT/US2013/068675 WO2014074572A1 (en) 2012-11-07 2013-11-06 Apparatus and method for operating a real time large diopter range sequential wavefront sensor

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RU2015121412A RU2015121412A (en) 2012-11-07 2013-11-06 DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME
RU2015121346A RU2015121346A (en) 2012-11-07 2013-11-06 DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME
RU2015121378A RU2015121378A (en) 2012-11-07 2013-11-06 DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME
RU2015121427A RU2015121427A (en) 2012-11-07 2013-11-06 DEVICE AND METHOD FOR OPERATING A SERIAL WAVE FRONT SENSOR OF A LARGE DIOPTRY RANGE OF REAL TIME
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