RU2012127177A - PHARMACEUTICAL IMMUNITY IMULATING COMPOSITION - Google Patents
PHARMACEUTICAL IMMUNITY IMULATING COMPOSITION Download PDFInfo
- Publication number
- RU2012127177A RU2012127177A RU2012127177/15A RU2012127177A RU2012127177A RU 2012127177 A RU2012127177 A RU 2012127177A RU 2012127177/15 A RU2012127177/15 A RU 2012127177/15A RU 2012127177 A RU2012127177 A RU 2012127177A RU 2012127177 A RU2012127177 A RU 2012127177A
- Authority
- RU
- Russia
- Prior art keywords
- pharmaceutical
- immunostimulating composition
- adjuvant
- antigen
- gram
- Prior art date
Links
- 230000036039 immunity Effects 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 claims abstract 6
- 241000894006 Bacteria Species 0.000 claims abstract 4
- 239000002671 adjuvant Substances 0.000 claims abstract 4
- 239000000427 antigen Substances 0.000 claims abstract 4
- 102000036639 antigens Human genes 0.000 claims abstract 4
- 108091007433 antigens Proteins 0.000 claims abstract 4
- 241000617624 Escherichia coli M17 Species 0.000 claims abstract 2
- 102000016943 Muramidase Human genes 0.000 claims abstract 2
- 108010014251 Muramidase Proteins 0.000 claims abstract 2
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 claims abstract 2
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims abstract 2
- 108010013639 Peptidoglycan Proteins 0.000 claims abstract 2
- 210000002421 cell wall Anatomy 0.000 claims abstract 2
- 150000004676 glycans Chemical class 0.000 claims abstract 2
- 229960000274 lysozyme Drugs 0.000 claims abstract 2
- 235000010335 lysozyme Nutrition 0.000 claims abstract 2
- 239000004325 lysozyme Substances 0.000 claims abstract 2
- 229920001282 polysaccharide Polymers 0.000 claims abstract 2
- 239000005017 polysaccharide Substances 0.000 claims abstract 2
- 108090000623 proteins and genes Proteins 0.000 claims abstract 2
- 102000004169 proteins and genes Human genes 0.000 claims abstract 2
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1. Фармацевтическая иммуностимулирующая композиция, содержащая антиген, преимущественно полисахаридной и/или белковой природы, и адъювант, представляющий собой высокоочищенный пептидогликан клеточной стенки грамотрицательных бактерий, модифицированный действием лизоцима, и/или его производные.2. Фармацевтическая иммуностимулирующая композиция по п.1, отличающаяся тем, что количество антигена к адъюванту выбирается в соотношении 1:10.3. Фармацевтическая иммуностимулирующая композиция по п.1, отличающаяся тем, что в качестве грамотрицательной бактерии используется Escherichia coli M17.1. A pharmaceutical immunostimulating composition containing an antigen, mainly of a polysaccharide and / or protein nature, and an adjuvant, which is a highly purified peptidoglycan of the cell wall of gram-negative bacteria, modified by the action of lysozyme, and / or its derivatives. The pharmaceutical immunostimulating composition according to claim 1, characterized in that the amount of antigen to adjuvant is selected in a ratio of 1: 10.3. The pharmaceutical immunostimulating composition according to claim 1, characterized in that Escherichia coli M17 is used as a gram-negative bacterium.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012127177/15A RU2012127177A (en) | 2012-06-29 | 2012-06-29 | PHARMACEUTICAL IMMUNITY IMULATING COMPOSITION |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012127177/15A RU2012127177A (en) | 2012-06-29 | 2012-06-29 | PHARMACEUTICAL IMMUNITY IMULATING COMPOSITION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012127177A true RU2012127177A (en) | 2014-01-20 |
Family
ID=49944595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012127177/15A RU2012127177A (en) | 2012-06-29 | 2012-06-29 | PHARMACEUTICAL IMMUNITY IMULATING COMPOSITION |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2012127177A (en) |
-
2012
- 2012-06-29 RU RU2012127177/15A patent/RU2012127177A/en unknown
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