RU2010129770A - VACCINE AGAINST INFLUENZA AND METHOD FOR PRODUCING IT - Google Patents
VACCINE AGAINST INFLUENZA AND METHOD FOR PRODUCING IT Download PDFInfo
- Publication number
- RU2010129770A RU2010129770A RU2010129770/15A RU2010129770A RU2010129770A RU 2010129770 A RU2010129770 A RU 2010129770A RU 2010129770/15 A RU2010129770/15 A RU 2010129770/15A RU 2010129770 A RU2010129770 A RU 2010129770A RU 2010129770 A RU2010129770 A RU 2010129770A
- Authority
- RU
- Russia
- Prior art keywords
- influenza virus
- carrier
- vaccine
- polymer
- vaccine against
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 claims abstract 8
- 241000712461 unidentified influenza virus Species 0.000 claims abstract 8
- 239000000427 antigen Substances 0.000 claims abstract 6
- 102000036639 antigens Human genes 0.000 claims abstract 6
- 108091007433 antigens Proteins 0.000 claims abstract 6
- 229960005486 vaccine Drugs 0.000 claims abstract 6
- VJOWMORERYNYON-UHFFFAOYSA-N 5-ethenyl-2-methylpyridine Chemical compound CC1=CC=C(C=C)C=N1 VJOWMORERYNYON-UHFFFAOYSA-N 0.000 claims abstract 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000002671 adjuvant Substances 0.000 claims abstract 4
- 239000012141 concentrate Substances 0.000 claims abstract 4
- 229920001577 copolymer Polymers 0.000 claims abstract 4
- 230000003612 virological effect Effects 0.000 claims abstract 4
- 241000287828 Gallus gallus Species 0.000 claims abstract 2
- 229940124873 Influenza virus vaccine Drugs 0.000 claims abstract 2
- 210000002257 embryonic structure Anatomy 0.000 claims abstract 2
- 230000000415 inactivating effect Effects 0.000 claims abstract 2
- 206010022000 influenza Diseases 0.000 claims abstract 2
- 238000002955 isolation Methods 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims abstract 2
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1. Способ получения вакцины против гриппа, включающий культивирование штаммов вируса гриппа на куриных эмбрионах, получение очищенного вирусного концентрата, инактивирование, расщепление вирусного концентрата с последующим выделением антигенов вируса гриппа, сведение в поливакцину, соединение с полимерным носителем, отличающийся тем, что в качестве полимерного носителя и адъюванта используют сополимер 2-метил-5-винилпиридин и N-винилпирролидона. ! 2. Вакцина против вируса гриппа, включающая очищенные антигены вируса гриппа с полимерным носителем, отличающаяся тем, что в качестве полимерного носителя и адъюванта является сополимер 2-метил-5-винилпиридин и N-винилпирролидона. ! 3. Вакцина против вируса гриппа по п.2, отличающаяся тем, что соотношение антиген-носитель составляет 1:5-30. 1. A method of obtaining a vaccine against influenza, including cultivating strains of the influenza virus on chicken embryos, obtaining purified viral concentrate, inactivating, cleaving the viral concentrate, followed by isolation of the influenza virus antigens, converting it into a multivirus vaccine, combining with a polymer carrier, characterized in that as a polymer the carrier and adjuvant use a copolymer of 2-methyl-5-vinylpyridine and N-vinylpyrrolidone. ! 2. A vaccine against influenza virus, including purified influenza virus antigens with a polymer carrier, characterized in that as a polymer carrier and adjuvant is a copolymer of 2-methyl-5-vinylpyridine and N-vinylpyrrolidone. ! 3. The influenza virus vaccine according to claim 2, characterized in that the ratio of carrier antigen is 1: 5-30.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010129770/15A RU2446824C2 (en) | 2010-07-20 | 2010-07-20 | Influenza vaccine and method for preparing it |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010129770/15A RU2446824C2 (en) | 2010-07-20 | 2010-07-20 | Influenza vaccine and method for preparing it |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010129770A true RU2010129770A (en) | 2012-01-27 |
| RU2446824C2 RU2446824C2 (en) | 2012-04-10 |
Family
ID=45786121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010129770/15A RU2446824C2 (en) | 2010-07-20 | 2010-07-20 | Influenza vaccine and method for preparing it |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2446824C2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618709A (en) * | 2019-09-24 | 2021-04-09 | 华南理工大学 | Pig oral vaccination slow release adjuvant and preparation method and application thereof |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2523614C1 (en) * | 2013-04-09 | 2014-07-20 | Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации | Vaccine against influenza and method for its preparation |
| RU2535153C1 (en) * | 2013-09-04 | 2014-12-10 | Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства России (ФГУП СПбНИИВС ФМБА России) | Method for preparing high-purity virion concentrate |
| RU2669810C1 (en) * | 2017-06-21 | 2018-10-16 | Станислав Анатольевич Кедик | Antiviral and immunomodulating combination of aminocaproic acid and copolymer of 2-methyl-5-vinylpyridine and n-vinylpyrrolidone |
| RU2662089C1 (en) * | 2017-06-21 | 2018-07-23 | Станислав Анатольевич Кедик | Complex nasal spray based on aminocaproic acid and a copolymer of 2-methyl-5-vinylpyridine and n-vinylpyrrolidone |
| RU2669811C1 (en) * | 2017-06-21 | 2018-10-16 | Станислав Анатольевич Кедик | Use of aminocaproic acid-based spray and copolymer of 2-methyl-5-vinylpyridine and n-vinylpyrrolidone |
| RU2740751C1 (en) * | 2019-08-28 | 2021-01-20 | Общество с ограниченной ответственностью "Развитие БиоТехнологий" | Method of producing tetravalent subunit influenza vaccine |
| RU2741003C1 (en) * | 2020-03-27 | 2021-01-22 | Евгений Дмитриевич Некрасов | Method for production of tetravalent subunit vaccine against influenza without adjuvants |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2164148C1 (en) * | 2000-08-09 | 2001-03-20 | Петров Рэм Викторович | Vaccine against influenza virus and method of its preparing |
-
2010
- 2010-07-20 RU RU2010129770/15A patent/RU2446824C2/en active IP Right Revival
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618709A (en) * | 2019-09-24 | 2021-04-09 | 华南理工大学 | Pig oral vaccination slow release adjuvant and preparation method and application thereof |
| CN112618709B (en) * | 2019-09-24 | 2023-11-03 | 华南理工大学 | A kind of sustained-release adjuvant for oral vaccination of pigs and its preparation method and application |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2446824C2 (en) | 2012-04-10 |
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