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RU2008124387A - ANXIOLYTIC PROPERTIES - Google Patents

ANXIOLYTIC PROPERTIES Download PDF

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Publication number
RU2008124387A
RU2008124387A RU2008124387/04A RU2008124387A RU2008124387A RU 2008124387 A RU2008124387 A RU 2008124387A RU 2008124387/04 A RU2008124387/04 A RU 2008124387/04A RU 2008124387 A RU2008124387 A RU 2008124387A RU 2008124387 A RU2008124387 A RU 2008124387A
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RU
Russia
Prior art keywords
amino acid
acid derivatives
anxiolytic properties
dimethoxyphenylethylamine
cooh
Prior art date
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RU2008124387/04A
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Russian (ru)
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RU2398761C2 (en
Inventor
Виктория Викторовна Баришполец (RU)
Виктория Викторовна Баришполец
Юлия Олеговна Федотова (RU)
Юлия Олеговна Федотова
Николай Сергеевич Сапронов (RU)
Николай Сергеевич Сапронов
Ирина Яковлевна Александрова (RU)
Ирина Яковлевна Александрова
Левон Борисович Пиотровский (RU)
Левон Борисович Пиотровский
Original Assignee
ГУ Научно-исследовательский институт экспериментальной медицины Российской Академии медицинских наук (ГУ НИИЭМ РАМН) (RU)
ГУ Научно-исследовательский институт экспериментальной медицины Российской Академии медицинских наук (ГУ НИИЭМ РАМН)
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Application filed by ГУ Научно-исследовательский институт экспериментальной медицины Российской Академии медицинских наук (ГУ НИИЭМ РАМН) (RU), ГУ Научно-исследовательский институт экспериментальной медицины Российской Академии медицинских наук (ГУ НИИЭМ РАМН) filed Critical ГУ Научно-исследовательский институт экспериментальной медицины Российской Академии медицинских наук (ГУ НИИЭМ РАМН) (RU)
Priority to RU2008124387/04A priority Critical patent/RU2398761C2/en
Publication of RU2008124387A publication Critical patent/RU2008124387A/en
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Publication of RU2398761C2 publication Critical patent/RU2398761C2/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1. Аминокислотные производные 3,4-диметоксифенилэтиламина общей формулы ! , ! где R: ! , ! , ! , ! , ! ; ! HX: (COOH)2(1, 2, 3, 4); ! HCl (5); ! Y=1 (1, 2); ! Y=3 (3); ! Y=0 (4, 5). ! 2. Аминокислотные производные по п.1, характеризующиеся тем, что обладают анксиолитической активностью.1. Amino acid derivatives of 3,4-dimethoxyphenylethylamine of the general formula! ! where R:! ! ! ! ! ; ! HX: (COOH) 2 (1, 2, 3, 4); ! HCl (5); ! Y = 1 (1, 2); ! Y = 3 (3); ! Y = 0 (4, 5). ! 2. Amino acid derivatives according to claim 1, characterized in that they have anxiolytic activity.

Claims (2)

1. Аминокислотные производные 3,4-диметоксифенилэтиламина общей формулы1. Amino acid derivatives of 3,4-dimethoxyphenylethylamine of the general formula
Figure 00000001
,
Figure 00000001
, где R:where R:
Figure 00000002
,
Figure 00000002
,
Figure 00000003
,
Figure 00000003
,
Figure 00000004
,
Figure 00000004
,
Figure 00000005
,
Figure 00000005
,
Figure 00000006
;
Figure 00000006
; HX: (COOH)2(1, 2, 3, 4);HX: (COOH) 2 (1, 2, 3, 4); HCl (5);HCl (5); Y=1 (1, 2);Y = 1 (1, 2); Y=3 (3);Y = 3 (3); Y=0 (4, 5).Y = 0 (4, 5). 2. Аминокислотные производные по п.1, характеризующиеся тем, что обладают анксиолитической активностью. 2. Amino acid derivatives according to claim 1, characterized in that they have anxiolytic activity.
RU2008124387/04A 2008-06-16 2008-06-16 Anxiolytics RU2398761C2 (en)

Priority Applications (1)

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RU2008124387/04A RU2398761C2 (en) 2008-06-16 2008-06-16 Anxiolytics

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RU2008124387/04A RU2398761C2 (en) 2008-06-16 2008-06-16 Anxiolytics

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RU2008124387A true RU2008124387A (en) 2009-12-27
RU2398761C2 RU2398761C2 (en) 2010-09-10

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2470661C2 (en) * 2010-11-11 2012-12-27 Учреждение Российской академии медицинских наук Научно-исследовательский институт нормальной физиологии имени П.К. Анохина РАМН Method for reducing mammalian anxiety level, method for reducing anxiety level, use of delta-opioid receptor antagonists not penetrating through brain-blood barrier for preparing anxiolytic agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2142813C1 (en) * 1999-03-25 1999-12-20 НИИ наркологии МЗРФ Tetrapeptide trp-nle-asp-phenh-ch(ch3)2 with anxiolytic activity
RU2314293C1 (en) * 2006-07-31 2008-01-10 Общество с ограниченной ответственностью "Флора и Фауна+" N-(5-hydroxynicotinoyl)-l-glutamic acid mono- and bivalent salts possessing psychotropic (antidepressant and anxiolytic), neuroprotective, geroprotective and anti-insult effect

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Effective date: 20120617