RU2008104741A - COMPLEX PROBIOTIC DRUG IN IMMOBILIZED AND LYOPHILIZED FORM - Google Patents
COMPLEX PROBIOTIC DRUG IN IMMOBILIZED AND LYOPHILIZED FORM Download PDFInfo
- Publication number
- RU2008104741A RU2008104741A RU2008104741/13A RU2008104741A RU2008104741A RU 2008104741 A RU2008104741 A RU 2008104741A RU 2008104741/13 A RU2008104741/13 A RU 2008104741/13A RU 2008104741 A RU2008104741 A RU 2008104741A RU 2008104741 A RU2008104741 A RU 2008104741A
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- RU
- Russia
- Prior art keywords
- vkpm
- bifidobacterium
- ratio
- bifidum
- enterosorbent
- Prior art date
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- 239000006041 probiotic Substances 0.000 title claims abstract 9
- 230000000529 probiotic effect Effects 0.000 title claims abstract 9
- 235000018291 probiotics Nutrition 0.000 title claims abstract 9
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 241000186000 Bifidobacterium Species 0.000 claims abstract 13
- 241001608472 Bifidobacterium longum Species 0.000 claims abstract 10
- 229940009291 bifidobacterium longum Drugs 0.000 claims abstract 10
- 241000186016 Bifidobacterium bifidum Species 0.000 claims abstract 8
- 229940002008 bifidobacterium bifidum Drugs 0.000 claims abstract 8
- 235000015097 nutrients Nutrition 0.000 claims abstract 7
- 241000186660 Lactobacillus Species 0.000 claims abstract 6
- 239000000203 mixture Substances 0.000 claims abstract 6
- 241000894006 Bacteria Species 0.000 claims abstract 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract 4
- 240000001046 Lactobacillus acidophilus Species 0.000 claims abstract 4
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 claims abstract 4
- 244000199866 Lactobacillus casei Species 0.000 claims abstract 4
- 235000013958 Lactobacillus casei Nutrition 0.000 claims abstract 4
- 229910052799 carbon Inorganic materials 0.000 claims abstract 4
- 229940039695 lactobacillus acidophilus Drugs 0.000 claims abstract 4
- 229940017800 lactobacillus casei Drugs 0.000 claims abstract 4
- 230000001681 protective effect Effects 0.000 claims abstract 4
- 239000012141 concentrate Substances 0.000 claims abstract 3
- 241000186018 Bifidobacterium adolescentis Species 0.000 claims abstract 2
- 240000006024 Lactobacillus plantarum Species 0.000 claims abstract 2
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims abstract 2
- 229940072205 lactobacillus plantarum Drugs 0.000 claims abstract 2
- 235000020183 skimmed milk Nutrition 0.000 claims 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 2
- 239000001509 sodium citrate Substances 0.000 claims 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1. Комплексный препарат-пробиотик, включающий носитель, представляющий собой пористый энтеросорбент и клетки бактерий-эубиотиков с питательной и защитной средами, иммобилизованные на указанном энтеросорбенте, отличающийся тем, что клетки бактерий-эубиотиков с питательной средой представляют собой лиофилизированный концентрат консорциума бифидобактерий, или лактобактерий, или их смесь с титром 108-1010 КОЕ/г, а в качестве пористого энтеросорбента он содержит углеродный энтеросорбент ВНИИТУ-1 или 2 при следующем соотношении компонентов препарата в сухом виде, мас.%: ! клетки с питательной средой консорциума бифидо-, или лактобактерий-эубиотиков, или их смесь с титром 108-1010 КОЕ/г1,0-15,0защитная среда0,1-10,0углеродный энтеросорбент ВНИИТУ-1 или 2остальное до 100% ! 2. Комплексный препарат-пробиотик по п.1, отличающийся тем, что в качестве консорциума штаммов бифидобактерий он содержит штаммы бифидобактерий: Bifldobacterium bifidum ВКПМ В-5799, Bifidobacterium longum ВКПМ В-5894, в соотношении 8:2, или Bifidobacterium bifidum 791 БАГ, Bifidobacterium bifidum ВКПМ В-5799, Bifidobacterium longum ВКПМ В-5894 в соотношении 6:3:1, или Bifidobacterium bifidum ВКПМ В-5799, Bifidobacterium longum ВКПМ AC-1252 и/или Bifidobacterium longum ВКПМ AC-1530 в соотношении 8:1:1, или Bifidobacterium bifidum ВКПМ В-5799, Bifidobacterium longum ВКПМ В-5894 и Bifidobacterium adolescentis ВКПМ В-2944 в соотношении 6:3:1 или Bifidobacterium bifidum ВКПМ В-5799, Bifidobacterium longum ВКПМ AC-1252 и Bifidobacterium adolescentis ВКПМ AC-1245 в соотношении 8:1:1. ! 3. Комплексный препарат-пробиотик по п.1, отличающийся тем, что в качестве консорциума штаммов лактобактерий он содержит штаммы лактобактерий: Lactobacillus acidophilus ВКПМ В-5863, Lactobacillus acidophilus ВКПМ В-4108, Lactobacillus plantarum ВКПМ В-3962, Lactobacillus plantarum ВКПМ В-5002; Lactobacillus casei ВКПМ В-5724, Lactobacillus casei ВКПМ В-3960 в соотношении 1:1:1:1:4:4.1. A comprehensive probiotic preparation, comprising a carrier, which is a porous enterosorbent and cells of eubiotics bacteria with a nutrient and protective medium immobilized on the specified enterosorbent, characterized in that the cells of eubiotics bacteria with a nutrient medium are a lyophilized concentrate of a bifidobacterium consortium, or , or their mixture with a titer of 108-1010 CFU / g, and as a porous enterosorbent it contains carbon enterosorbent VNIITU-1 or 2 in the following ratio of components pr Paratov in dry form, wt.%: cells with a nutrient medium of a consortium of bifidobacteria or lactobacilli-eubiotics, or their mixture with a titer of 108-1010 CFU / g 1.0-15.0 protective medium 0.1-10.0 carbon enterosorbent VNIITU-1 or 2, up to 100%! 2. The complex probiotic preparation according to claim 1, characterized in that as a consortium of strains of bifidobacteria, it contains strains of bifidobacteria: Bifldobacterium bifidum VKPM B-5799, Bifidobacterium longum VKPM B-5894, in a ratio of 8: 2, or Bifidobacterium bifum 79 , Bifidobacterium bifidum VKPM B-5799, Bifidobacterium longum VKPM B-5894 in the ratio 6: 3: 1, or Bifidobacterium bifidum VKPM B-5799, Bifidobacterium longum VKPM AC-1252 and / or Bifidobacterium longum VKPM 8: 1 : 1, or Bifidobacterium bifidum VKPM B-5799, Bifidobacterium longum VKPM B-5894 and Bifidobacterium adolescentis VKPM B-2944 in the ratio 6: 3: 1 or Bifidobacterium bifidum VKPM B-5799, Bifidobacterium 12um bifidum Bumidum VKPM VKPM AC-1245 in the ratio of 8: 1: 1. ! 3. The complex probiotic preparation according to claim 1, characterized in that, as a consortium of strains of lactobacilli, it contains strains of lactobacilli: Lactobacillus acidophilus VKPM B-5863, Lactobacillus acidophilus VKPM B-4108, Lactobacillus plantarum VKPM B-3962M Lactobacactum plantPum B-3962, Plantactum -5002; Lactobacillus casei VKPM B-5724, Lactobacillus casei VKPM B-3960 in a ratio of 1: 1: 1: 1: 4: 4.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008104741/13A RU2371479C1 (en) | 2008-02-12 | 2008-02-12 | Complex probiotic medicine in immobilised and lyophilised form |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008104741/13A RU2371479C1 (en) | 2008-02-12 | 2008-02-12 | Complex probiotic medicine in immobilised and lyophilised form |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008104741A true RU2008104741A (en) | 2009-08-20 |
| RU2371479C1 RU2371479C1 (en) | 2009-10-27 |
Family
ID=41150541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008104741/13A RU2371479C1 (en) | 2008-02-12 | 2008-02-12 | Complex probiotic medicine in immobilised and lyophilised form |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2371479C1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2962045B1 (en) * | 2010-07-05 | 2012-08-17 | Bifinove | MACROMOLECULAR COMPLEX OF BACTERIAL ORIGIN AND USE OF SAID MOLECULAR COMPLEX FOR PREVENTING AND TREATING INFLAMMATORY RHUMATISMS |
| RU2530174C2 (en) * | 2012-09-14 | 2014-10-10 | Закрытое Акционерное Общество "Производственная Фармацевтическая Компания Обновление" | Bacterial system for normalising microbiocenosis of human and animal organism |
| RU2586486C1 (en) * | 2015-08-26 | 2016-06-10 | Алексей Владимирович Шабалин | Method for production of fermented milk beverage |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2118535C1 (en) * | 1997-03-20 | 1998-09-10 | Институт клинической и экспериментальной лимфологии СО РАМН | Complex bacterial preparation |
| RU2164801C1 (en) * | 1999-12-06 | 2001-04-10 | Дочернее государственное унитарное экспериментально-производственное предприятие "Вектор-Биальгам" | Preparation-probiotic as dry immobilized form |
| RU2317089C2 (en) * | 2006-01-10 | 2008-02-20 | Закрытое акционерное общество "Вектор-БиАльгам" | Complex preparation-probiotic in immobilized and lyophilized form and method for its obtaining |
-
2008
- 2008-02-12 RU RU2008104741/13A patent/RU2371479C1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2371479C1 (en) | 2009-10-27 |
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