RU2007140808A - PHARMACEUTICAL INJECTION PRODUCT BASED ON A LOW-MOLECULAR INTERFERON INDUCTOR - Google Patents
PHARMACEUTICAL INJECTION PRODUCT BASED ON A LOW-MOLECULAR INTERFERON INDUCTOR Download PDFInfo
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- RU2007140808A RU2007140808A RU2007140808/15A RU2007140808A RU2007140808A RU 2007140808 A RU2007140808 A RU 2007140808A RU 2007140808/15 A RU2007140808/15 A RU 2007140808/15A RU 2007140808 A RU2007140808 A RU 2007140808A RU 2007140808 A RU2007140808 A RU 2007140808A
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- Prior art keywords
- components
- solvent
- injection preparation
- preparation according
- pharmacological
- Prior art date
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- 238000002347 injection Methods 0.000 title claims abstract 11
- 239000007924 injection Substances 0.000 title claims abstract 11
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract 18
- 230000000144 pharmacologic effect Effects 0.000 claims abstract 10
- 239000002904 solvent Substances 0.000 claims abstract 8
- 230000000087 stabilizing effect Effects 0.000 claims abstract 6
- 239000002799 interferon inducing agent Substances 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 4
- 239000001509 sodium citrate Substances 0.000 claims abstract 4
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract 4
- 239000001488 sodium phosphate Substances 0.000 claims abstract 4
- 229910000162 sodium phosphate Inorganic materials 0.000 claims abstract 4
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 4
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract 2
- 239000013543 active substance Substances 0.000 claims abstract 2
- 229940035674 anesthetics Drugs 0.000 claims abstract 2
- 239000011260 aqueous acid Substances 0.000 claims abstract 2
- AEKLPNAELPOQBI-RHLRHBBGSA-L disodium butanedioate (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol Chemical compound [Na+].C(CCC(=O)[O-])(=O)[O-].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Na+] AEKLPNAELPOQBI-RHLRHBBGSA-L 0.000 claims abstract 2
- 239000003193 general anesthetic agent Substances 0.000 claims abstract 2
- 229960004194 lidocaine Drugs 0.000 claims abstract 2
- 229940053973 novocaine Drugs 0.000 claims abstract 2
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000000243 solution Substances 0.000 claims abstract 2
- MPMFCABZENCRHV-UHFFFAOYSA-N tilorone Chemical compound C1=C(OCCN(CC)CC)C=C2C(=O)C3=CC(OCCN(CC)CC)=CC=C3C2=C1 MPMFCABZENCRHV-UHFFFAOYSA-N 0.000 claims abstract 2
- 229950006823 tilorone Drugs 0.000 claims abstract 2
- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 claims abstract 2
- 229950002569 trimecaine Drugs 0.000 claims abstract 2
- 239000008215 water for injection Substances 0.000 claims abstract 2
- 239000007788 liquid Substances 0.000 claims 1
- 239000003633 blood substitute Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1. Фармакологический инъекционный препарат, содержащий в качестве активного вещества низкомолекулярный индуктор интерферона и растворитель, отличающийся тем, что в качестве низкомолекулярного индуктора интерферона он содержит тилорон, например, при следующем соотношении компонентов, мас.%: ! тилорон0,001-10,000растворительостальное ! 2. Фармакологический инъекционный препарат по п.1, отличающийся тем, что в качестве растворителя он содержит, например, воду для инъекций, или изотонический раствор натрия хлорида, или реамберин, или кровезамещающую жидкость, например «Гемодез-Н», или их физиологически приемлемую смесь. ! 3. Фармакологический инъекционный препарат по п.1, отличающийся тем, что он дополнительно содержит стабилизирующие компоненты, при этом соотношение компонентов в растворе устанавливается, например, следующее, мас.%: ! тилорон0,001-10,000стабилизирующие компоненты0,05-7,00растворительостальное ! 4. Фармакологический инъекционный препарат по п.3, отличающийся тем, что в качестве стабилизирующих компонентов он содержит, например, кислоту лимонную и натрия фосфат двузамещенный 12-водный, или кислоту лимонную и натрия цитрат при следующем содержании компонентов в смеси, мас.%: ! натрия фосфат двузамещенный 12-водный0,05-3,00натрия цитрат0,05-3,00кислота лимонная0,10-1,00 ! 5. Фармакологический инъекционный препарат по п.1, отличающийся тем, что он дополнительно содержит анестетики, например лнекаин, или лидокаин, или тримекаин, или новокаин, при их содержании в препарате от 0,25 до 5,00 мас.%.1. A pharmacological injection preparation containing a low molecular weight interferon inducer and a solvent as an active substance, characterized in that it contains tilorone as a low molecular weight interferon inducer, for example, in the following ratio of components, wt.%:! tiloron 0.001-10,000 solvent 2. The pharmacological injection preparation according to claim 1, characterized in that, as a solvent, it contains, for example, water for injection, or isotonic sodium chloride solution, or reamberin, or a blood substitute, for example, "Hemodez-N", or their physiologically acceptable mixture. ! 3. The pharmacological injection preparation according to claim 1, characterized in that it further comprises stabilizing components, while the ratio of components in the solution is established, for example, the following, wt.%:! tiloron 0.001-10,000 stabilizing components 0.05-7.00 solvent 4. The pharmacological injection preparation according to claim 3, characterized in that, as stabilizing components, it contains, for example, citric acid and sodium phosphate disubstituted 12-aqueous, or citric acid and sodium citrate in the following components in a mixture, wt.%: ! sodium phosphate disubstituted 12-water 0.05-3.00 sodium citrate 0.05-3.00 citric acid 0.10-1.00! 5. The pharmacological injection preparation according to claim 1, characterized in that it further comprises anesthetics, for example, lnecain, or lidocaine, or trimecaine, or novocaine, when their content in the preparation is from 0.25 to 5.00 wt.%.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007140808/15A RU2364390C1 (en) | 2007-11-07 | 2007-11-07 | Pharmaceutical injection tilorone-based composition for treatment of diseases with immunodeficiency signs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2007140808/15A RU2364390C1 (en) | 2007-11-07 | 2007-11-07 | Pharmaceutical injection tilorone-based composition for treatment of diseases with immunodeficiency signs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007140808A true RU2007140808A (en) | 2009-05-20 |
| RU2364390C1 RU2364390C1 (en) | 2009-08-20 |
Family
ID=41021142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007140808/15A RU2364390C1 (en) | 2007-11-07 | 2007-11-07 | Pharmaceutical injection tilorone-based composition for treatment of diseases with immunodeficiency signs |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2364390C1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2423971C1 (en) * | 2010-06-01 | 2011-07-20 | Закрытое акционерное общество "Биологические исследования и системы" | Method of accelerating healing of skin injuries, caused by denervation and blood supply disturbance |
| RU2625744C1 (en) * | 2016-05-17 | 2017-07-18 | Закрытое Акционерное Общество "Биологические Исследования И Системы" (Зао "Бис") | Method for prevention of exacerbation of bronchial asthma and chronic obstructive pulmonary disease |
-
2007
- 2007-11-07 RU RU2007140808/15A patent/RU2364390C1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2364390C1 (en) | 2009-08-20 |
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