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RU2006120491A - Комбинация для лечения пролиферативных заболеваний - Google Patents

Комбинация для лечения пролиферативных заболеваний Download PDF

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Publication number
RU2006120491A
RU2006120491A RU2006120491/15A RU2006120491A RU2006120491A RU 2006120491 A RU2006120491 A RU 2006120491A RU 2006120491/15 A RU2006120491/15 A RU 2006120491/15A RU 2006120491 A RU2006120491 A RU 2006120491A RU 2006120491 A RU2006120491 A RU 2006120491A
Authority
RU
Russia
Prior art keywords
agent
protein tyrosine
tyrosine phosphatase
mitotic kinesin
reduces
Prior art date
Application number
RU2006120491/15A
Other languages
English (en)
Russian (ru)
Inventor
М. Джеймс НИКОЛС (US)
М. Джеймс НИКОЛС
Маргорет С. ЛИ (US)
Маргорет С. ЛИ
Кертис КЕЙТ (US)
Кертис КЕЙТ
Йанзхен ЗХАНГ (US)
Йанзхен ЗХАНГ
Original Assignee
Комбинаторкс, Инкорпорейтед (Us)
Комбинаторкс, Инкорпорейтед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/855,130 external-priority patent/US20050100508A1/en
Application filed by Комбинаторкс, Инкорпорейтед (Us), Комбинаторкс, Инкорпорейтед filed Critical Комбинаторкс, Инкорпорейтед (Us)
Publication of RU2006120491A publication Critical patent/RU2006120491A/ru

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
RU2006120491/15A 2003-11-12 2004-11-09 Комбинация для лечения пролиферативных заболеваний RU2006120491A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51955103P 2003-11-12 2003-11-12
US60/519,551 2003-11-12
US10/855,130 2004-05-27
US10/855,130 US20050100508A1 (en) 2003-11-12 2004-05-27 Methods for identifying drug combinations for the treatment of proliferative diseases

Publications (1)

Publication Number Publication Date
RU2006120491A true RU2006120491A (ru) 2007-12-20

Family

ID=34556562

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006120491/15A RU2006120491A (ru) 2003-11-12 2004-11-09 Комбинация для лечения пролиферативных заболеваний

Country Status (13)

Country Link
EP (1) EP1689352A2 (es)
JP (1) JP2007524657A (es)
KR (1) KR20060118514A (es)
AR (1) AR046841A1 (es)
AU (1) AU2004289311A1 (es)
BR (1) BRPI0416390A (es)
CA (1) CA2545423A1 (es)
IL (1) IL175611A0 (es)
IS (1) IS8496A (es)
NO (1) NO20062358L (es)
RU (1) RU2006120491A (es)
TW (1) TW200526777A (es)
WO (1) WO2005046607A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009225877B2 (en) * 2008-03-18 2014-11-20 Genentech, Inc. Combinations of an anti-HER2 antibody-drug conjugate and chemotherapeutic agents, and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2235420A1 (en) * 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US6569853B1 (en) * 2000-11-06 2003-05-27 Combinatorx, Incorporated Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders

Also Published As

Publication number Publication date
AU2004289311A1 (en) 2005-05-26
EP1689352A2 (en) 2006-08-16
BRPI0416390A (pt) 2007-02-21
AR046841A1 (es) 2005-12-28
NO20062358L (no) 2006-07-12
IS8496A (is) 2006-06-02
KR20060118514A (ko) 2006-11-23
CA2545423A1 (en) 2005-05-26
WO2005046607A3 (en) 2012-12-20
IL175611A0 (en) 2008-04-13
WO2005046607A2 (en) 2005-05-26
TW200526777A (en) 2005-08-16
JP2007524657A (ja) 2007-08-30

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Legal Events

Date Code Title Description
FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20071210