RU2004129284A - AMBROXOL FOR TREATMENT OF PAIN AND MOUTH - Google Patents

Claims (12)

1. The use of ambroxol or one of its pharmacologically acceptable salts for the manufacture of a medicament for the treatment of pain in the oral cavity and / or pharynx from the group including acute sore throat, aphthae, gingivitis, periodontopathy, pain arising from pressure on the denture, pain in the oropharynx after surgery, damage to the mucous membrane in the oral cavity and pharynx, and simple vesicle lichen in the oral cavity and pharynx. 2. A pharmaceutical composition comprising ambroxol or one of its pharmacologically acceptable salts and one or more active substances selected from the group consisting of antiseptics, vitamins, corticoids, anti-inflammatory drugs, antibiotics, antifungal agents and proteolytic enzymes. 3. A pharmaceutical composition containing ambroxol or one of its pharmacologically acceptable salts and one or more active substances selected from the group consisting of lysozyme hydrochloride, dipotassium glycyrrhizinate, ammonium glycyrrhizinate, cetylpyridinium chloride, chlorpheniramine maleate, noscapine, decalfalinorphan potassium chloride, decafalinorin chloride guayacolsulfonate, d1-methylephedrine hydrochloride, chlorhexidine hydrochloride and potassium cresolsulfonate. 4. A pharmaceutical composition comprising ambroxol, bromhexine or their pharmacologically acceptable salts and pharmaceutical excipients. 5. The pharmaceutical composition according to any one of claims 2 to 4, characterized in that the single dose contains from 15 to 50 mg of ambroxol. 6. A solid, sucking or slowly dissolving dosage form of a pharmaceutical composition according to any one of claims 2 to 4. 7. Semi-solid dosage form of the pharmaceutical composition according to one of claims 2 to 5 in the form of a gel. 8. The use of the pharmaceutical composition according to one of claims 2-5 for the manufacture of a medicament for the treatment of pain in the oral cavity and / or pharynx from the group including acute sore throat, aphthae, gingivitis, periodontopathy, pain arising from pressure on the tooth prosthesis, pain in the oropharynx after surgery, damage to the mucous membrane in the oral cavity and pharynx, and simple vesicle lichen in the oral cavity and pharynx. 9. The use of a pharmaceutical composition comprising ambroxol hydrochloride, a flavoring agent, a lubricant, a matrix, a sweetener and polyethylene glycol for the manufacture of a medicament for the treatment of pain in the oral cavity and / or pharynx from the group comprising acute sore throat, aphthae, gingivitis, periodontopathy, pain arising from pressure on the denture, pain in the oropharynx after surgery, damage to the mucous membrane in the mouth and pharynx, and simple vesiculate Shay in the mouth and throat. 10. The use of a sugar alcohol-based suction tablet containing ambroxol as a matrix, characterized by the presence of a pharmaceutically acceptable layered silicate and polyethylene glycol in its composition, optionally along with other pharmaceutical excipients, flavors, or flavorings, for the treatment of pain in the oral cavity and / or pharynx from the group including acute sore throat, aphthae, gingivitis, periodontopathy, pain arising from pressure on the denture, pain in the oropharynx after surgery interventions, damage to the mucous membrane in the oral cavity and pharynx, and simple vesicle lichen in the oral cavity and pharynx. 11. The use of ambroxol according to claim 1 for the manufacture of a medicament with an analgesic effect, manifested for at least 3 hours after prima. 12. The use of the pharmaceutical composition according to any one of claims 2 to 5 for the manufacture of a medicament with a painkiller effect, manifested for at least 3 hours after administration.