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RU2003131081A - (s)-метил 3-(3-нитрофенил) пентаноат - Google Patents

(s)-метил 3-(3-нитрофенил) пентаноат Download PDF

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Publication number
RU2003131081A
RU2003131081A RU2003131081/04A RU2003131081A RU2003131081A RU 2003131081 A RU2003131081 A RU 2003131081A RU 2003131081/04 A RU2003131081/04 A RU 2003131081/04A RU 2003131081 A RU2003131081 A RU 2003131081A RU 2003131081 A RU2003131081 A RU 2003131081A
Authority
RU
Russia
Prior art keywords
nitrophenyl
methyl
pentanoat
pentanoate
Prior art date
Application number
RU2003131081/04A
Other languages
English (en)
Other versions
RU2263106C2 (ru
Inventor
Джеймс Р ГЕЙДЖ (US)
Джеймс Р ГЕЙДЖ
Роберт С КЕЛЛИ (US)
Роберт С КЕЛЛИ
Брэдли Д ХЬЮИТТ (US)
Брэдли Д ХЬЮИТТ
Original Assignee
Фармация Энд Апджон Компани (Us)
Фармация Энд Апджон Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармация Энд Апджон Компани (Us), Фармация Энд Апджон Компани filed Critical Фармация Энд Апджон Компани (Us)
Publication of RU2003131081A publication Critical patent/RU2003131081A/ru
Application granted granted Critical
Publication of RU2263106C2 publication Critical patent/RU2263106C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (1)

  1. (S)-метил 3-(3-нитрофенил)пентаноат.
RU2003131081/04A 1997-09-11 2003-10-21 (s)-метил 3-(3-нитрофенил) пентаноат RU2263106C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5861897P 1997-09-11 1997-09-11
US60/058,618 1997-09-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2000109277/04A Division RU2223958C2 (ru) 1997-09-11 1998-09-03 Новый способ получения ингибитора протеазы

Publications (2)

Publication Number Publication Date
RU2003131081A true RU2003131081A (ru) 2005-04-10
RU2263106C2 RU2263106C2 (ru) 2005-10-27

Family

ID=22017924

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2000109277/04A RU2223958C2 (ru) 1997-09-11 1998-09-03 Новый способ получения ингибитора протеазы
RU2003131081/04A RU2263106C2 (ru) 1997-09-11 2003-10-21 (s)-метил 3-(3-нитрофенил) пентаноат

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2000109277/04A RU2223958C2 (ru) 1997-09-11 1998-09-03 Новый способ получения ингибитора протеазы

Country Status (20)

Country Link
US (2) US6077963A (ru)
EP (1) EP1015441B1 (ru)
JP (3) JP4462760B2 (ru)
KR (1) KR100569771B1 (ru)
CN (3) CN1298714C (ru)
AT (1) ATE266654T1 (ru)
CA (1) CA2300204C (ru)
CZ (1) CZ298847B6 (ru)
DE (1) DE69823844T2 (ru)
DK (1) DK1015441T3 (ru)
ES (1) ES2221199T3 (ru)
FI (1) FI120973B (ru)
HU (1) HU228986B1 (ru)
NO (1) NO321835B1 (ru)
NZ (1) NZ503338A (ru)
PL (1) PL193240B1 (ru)
PT (1) PT1015441E (ru)
RU (2) RU2223958C2 (ru)
SK (1) SK284974B6 (ru)
WO (1) WO1999012919A1 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60000660T2 (de) 1999-03-18 2003-06-26 Pharmacia & Upjohn Co., Kalamazoo Verbesserte verfahren fur assymmetrische hydrogenation
US6552204B1 (en) * 2000-02-04 2003-04-22 Roche Colorado Corporation Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
DE10108470A1 (de) * 2001-02-22 2002-09-05 Boehringer Ingelheim Pharma Verfahren zur Herstellung optisch aktiver Dihydropyrone
US6500963B2 (en) 2001-02-22 2002-12-31 Boehringer Ingelheim Pharma Kg Process for preparing optically active dihydropyrones
US6987123B2 (en) * 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
CN1301244C (zh) 2002-02-07 2007-02-21 住友化学工业株式会社 生产(r)－3－羟基－3－(2－苯基乙基)己酸及其中间体的方法
DE10313118A1 (de) * 2003-03-24 2004-10-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Enantioselektive Hydrierung von Intermediaten bei der Tipranavir-Synthese
US7512945B2 (en) * 2003-12-29 2009-03-31 Intel Corporation Method and apparatus for scheduling the processing of commands for execution by cryptographic algorithm cores in a programmable network processor
CN100448836C (zh) * 2005-06-03 2009-01-07 浙江中贝化工有限公司 一种抗艾滋病药物关键中间体的制备方法
AU2006283297B2 (en) * 2005-08-24 2012-07-26 Pfizer Inc. Methods for the preparation of HCV polymerase inhibitors
WO2009069535A1 (en) * 2007-11-30 2009-06-04 Semiconductor Energy Laboratory Co., Ltd. Light-emitting element, light-emitting device, and electronic device
WO2013016840A1 (zh) * 2011-07-29 2013-02-07 安徽省新星药物开发有限责任公司 用于合成他喷他多或其类似物的新中间体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1355667A (fr) * 1963-02-05 1964-03-20 Meci Materiel Elect Contr Gaine tubulaire pour électrode servant à la mesure du ph
FR1355668A (fr) * 1963-02-05 1964-03-20 Moteur rotatif à combustion interne perfectionné
FR2096877B1 (ru) * 1970-07-09 1973-08-10 Hexachimie
JPH0665657B2 (ja) * 1984-11-08 1994-08-24 日本化薬株式会社 光学活性マンデル酸の製法
JPH072677B2 (ja) * 1988-02-19 1995-01-18 株式会社クラレ （±）―２―ヒドロキシ―４―フェニルブタン酸の光学分割法
JPH01221345A (ja) * 1988-02-27 1989-09-04 Ajinomoto Co Inc マンデル酸誘導体の光学分割方法
JP3084577B2 (ja) * 1991-09-27 2000-09-04 山川薬品工業株式会社 光学活性なアトロラクチン酸の製造方法および製造の中間体
JP3178086B2 (ja) * 1992-06-17 2001-06-18 山川薬品工業株式会社 光学活性α−メチルベンジルアミンの製造方法
ZA938019B (en) * 1992-11-13 1995-04-28 Upjohn Co Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses
EP0729464A1 (en) * 1993-11-19 1996-09-04 PARKE, DAVIS & COMPANY 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents
IL129871A (en) * 1994-05-06 2003-11-23 Pharmacia & Upjohn Inc Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections
RU2074169C1 (ru) * 1995-05-10 1997-02-27 Акционерное общество открытого типа "Химпром" Способ получения этилового эфира п-нитробензойной кислоты

Also Published As

Publication number Publication date
EP1015441A1 (en) 2000-07-05
HUP0003593A3 (en) 2002-12-28
KR20010023864A (ko) 2001-03-26
ATE266654T1 (de) 2004-05-15
NO321835B1 (no) 2006-07-10
JP2010090157A (ja) 2010-04-22
PL339138A1 (en) 2000-12-04
CN100471832C (zh) 2009-03-25
JP2001515895A (ja) 2001-09-25
US6265604B1 (en) 2001-07-24
ES2221199T3 (es) 2004-12-16
US6077963A (en) 2000-06-20
RU2263106C2 (ru) 2005-10-27
CN1990452A (zh) 2007-07-04
AU9296598A (en) 1999-03-29
CA2300204C (en) 2006-12-12
HK1030418A1 (en) 2001-05-04
DE69823844T2 (de) 2005-04-14
HK1063776A1 (en) 2005-01-14
CZ2000804A3 (cs) 2000-08-16
PL193240B1 (pl) 2007-01-31
HUP0003593A2 (hu) 2001-02-28
JP2009138002A (ja) 2009-06-25
CN1511820A (zh) 2004-07-14
AU743496B2 (en) 2002-01-24
NZ503338A (en) 2002-03-01
JP4462760B2 (ja) 2010-05-12
HK1104027A1 (zh) 2008-01-04
JP5016621B2 (ja) 2012-09-05
CN1268947A (zh) 2000-10-04
CN1284763C (zh) 2006-11-15
PT1015441E (pt) 2004-08-31
FI120973B (fi) 2010-05-31
DK1015441T3 (da) 2004-07-26
CZ298847B6 (cs) 2008-02-27
CA2300204A1 (en) 1999-03-18
HU228986B1 (en) 2013-07-29
SK284974B6 (sk) 2006-03-02
NO20001274L (no) 2000-05-10
KR100569771B1 (ko) 2006-04-11
RU2223958C2 (ru) 2004-02-20
EP1015441B1 (en) 2004-05-12
NO20001274D0 (no) 2000-03-10
JP5266194B2 (ja) 2013-08-21
CN1298714C (zh) 2007-02-07
DE69823844D1 (de) 2004-06-17
FI20000553L (fi) 2000-03-10
WO1999012919A1 (en) 1999-03-18
SK2262000A3 (en) 2000-10-09

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