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RU2003129265A - Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии - Google Patents

Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии Download PDF

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Publication number
RU2003129265A
RU2003129265A RU2003129265/13A RU2003129265A RU2003129265A RU 2003129265 A RU2003129265 A RU 2003129265A RU 2003129265/13 A RU2003129265/13 A RU 2003129265/13A RU 2003129265 A RU2003129265 A RU 2003129265A RU 2003129265 A RU2003129265 A RU 2003129265A
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bacterial strain
group
milk
composition according
pharmaceutical composition
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RU2003129265/13A
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RU2312892C2 (ru
Inventor
Беда Мартин ШТАДЛЕР (CH)
Беда Мартин ШТАДЛЕР
Моник ФОГЕЛ (CH)
Моник ФОГЕЛ
Жак-Эдуар ЖЕРМОН (CH)
Жак-Эдуар ЖЕРМОН
Родолф ФРИЧЕ (CH)
Родолф ФРИЧЕ
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Сосьете де Продюи Нестле С.А. (CH)
Сосьете Де Продюи Нестле С.А.
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Publication of RU2003129265A publication Critical patent/RU2003129265A/ru
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Publication of RU2312892C2 publication Critical patent/RU2312892C2/ru

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Physiology (AREA)
  • Wood Science & Technology (AREA)
  • Birds (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Claims (10)

1. Бактериальный штамм группы молочно-кислой бактерии, экспрессирующий поверхностный полипептид, который содержит пептидную последовательность, имитирующую, по меньшей мере, часть конформационного эпитопа молекулы IgE, где указанным поверхностным полипептидом является заякоренная на клеточной поверхности протеаза L. bulgaricus.
2. Бактериальный штамм по п.1, выбранный из группы Lactobacillus или группы Bifidobacterium, или группы Lactococcus, и более предпочтительно происходящий из групп L. acidofilicus, L. johnsomi, L. gasseri, L. casei, L. paracasei или L. reuteri.
3. Бактериальный штамм по любому из предыдущих пунктов, где пептидная последовательность произведена из последовательности, выбранной из SEQ ID No.1 - SEQID No.19.
4. Пищевая композиция, содержащая бактериальный штамм по любому из предыдущих пунктов или его супернатант.
5. Пищевая композиция по п.4, выбранная из группы, состоящей из молока, йогурта, творога, сыра, кисло-молочных продуктов, продуктов на основе ферментированного молока, мороженого, продуктов на основе ферментированных злаков, порошков на основе молока, детских смесей или корма для домашних животных.
6. Пищевая композиция по любому из п.4 или 5, где бактериальный штамм содержится в ней в количестве от 107 до 1012 кое на дозированную форму.
7. Фармацевтическая композиция, содержащая бактериальный штамм по любому из пп.1-3.
8. Фармацевтическая композиция по п.7, где бактериальный штамм содержится в ней в количестве от 1010 до 1012 кое на дозированную форму.
9. Применение бактериального штамма по любому из пп.1-3 для приготовления принимаемого внутрь носителя для лечения аллергии и/или предотвращения появления аллергических реакций.
10. Применение фармацевтической композиции по любому из пп.5-8 для приготовления принимаемого внутрь носителя для лечения аллергии и/или появления начала аллергических реакций.
RU2003129265/13A 2001-03-02 2002-03-04 Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии RU2312892C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01105138.0 2001-03-02
EP01105138A EP1239032A1 (en) 2001-03-02 2001-03-02 Lactic acid bacteria as agents for treating and preventing allergy

Publications (2)

Publication Number Publication Date
RU2003129265A true RU2003129265A (ru) 2005-04-10
RU2312892C2 RU2312892C2 (ru) 2007-12-20

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Family Applications (1)

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RU2003129265/13A RU2312892C2 (ru) 2001-03-02 2002-03-04 Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии

Country Status (17)

Country Link
US (1) US7235395B2 (ru)
EP (2) EP1239032A1 (ru)
JP (1) JP2004528034A (ru)
KR (2) KR20080111172A (ru)
CN (1) CN1505678A (ru)
AR (1) AR035761A1 (ru)
AU (1) AU2002256639B2 (ru)
BR (1) BR0207749A (ru)
CA (1) CA2438833A1 (ru)
IL (1) IL157468A0 (ru)
MX (1) MXPA03007881A (ru)
NO (1) NO20033796L (ru)
NZ (1) NZ527861A (ru)
PL (1) PL367208A1 (ru)
RU (1) RU2312892C2 (ru)
WO (1) WO2002086102A1 (ru)
ZA (1) ZA200307680B (ru)

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Also Published As

Publication number Publication date
MXPA03007881A (es) 2003-12-04
NO20033796L (no) 2003-10-31
US20040265290A1 (en) 2004-12-30
EP1239032A1 (en) 2002-09-11
KR20080111172A (ko) 2008-12-22
IL157468A0 (en) 2004-03-28
AU2002256639B2 (en) 2006-10-19
NO20033796D0 (no) 2003-08-26
CA2438833A1 (en) 2002-10-31
PL367208A1 (en) 2005-02-21
EP1370640A1 (en) 2003-12-17
JP2004528034A (ja) 2004-09-16
BR0207749A (pt) 2004-06-01
KR20030082950A (ko) 2003-10-23
CN1505678A (zh) 2004-06-16
RU2312892C2 (ru) 2007-12-20
AR035761A1 (es) 2004-07-07
ZA200307680B (en) 2005-01-13
WO2002086102A1 (en) 2002-10-31
US7235395B2 (en) 2007-06-26
NZ527861A (en) 2005-02-25

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Effective date: 20110305