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RU2002102491A - Quinoline Carboxylic Acid Derivatives Or Their Salts - Google Patents

Quinoline Carboxylic Acid Derivatives Or Their Salts

Info

Publication number
RU2002102491A
RU2002102491A RU2002102491/04A RU2002102491A RU2002102491A RU 2002102491 A RU2002102491 A RU 2002102491A RU 2002102491/04 A RU2002102491/04 A RU 2002102491/04A RU 2002102491 A RU2002102491 A RU 2002102491A RU 2002102491 A RU2002102491 A RU 2002102491A
Authority
RU
Russia
Prior art keywords
carboxylic acid
difluoropyridin
dihydroquinoline
bromo
oxo
Prior art date
Application number
RU2002102491/04A
Other languages
Russian (ru)
Other versions
RU2236408C2 (en
Inventor
Акира ЯЗАКИ
Есико НИИНО
Ясухиро КУРАМОТО
Юзо ХИРАО
Есихиро ОХСИТА
Норихиро ХАЯСИ
Хиротака АМАНО
Original Assignee
Вакунага Фармасьютикал КО., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вакунага Фармасьютикал КО., Лтд. filed Critical Вакунага Фармасьютикал КО., Лтд.
Publication of RU2002102491A publication Critical patent/RU2002102491A/en
Application granted granted Critical
Publication of RU2236408C2 publication Critical patent/RU2236408C2/en

Links

Claims (5)

1. 1-(6-Амино-3,5-дифторпиридин-2-ил)-8-бром-7-(3-этил-аминоазетидин-1-ил)-6-фтор-4-оксо-l,4-дигидрохинолин-3-карбоновая кислота или ее соль.1.1- (6-amino-3,5-difluoropyridin-2-yl) -8-bromo-7- (3-ethyl-aminoazetidin-1-yl) -6-fluoro-4-oxo-l, 4- dihydroquinoline-3-carboxylic acid or its salt. 2. 1-(6-амино-3,5-дифторпиридин-2-ил)-8-бром-7-(3-этиламиноазетидин-1-ил)-6-фтор-4-оксо-1,4-дигидрохинолин-3-карбоновая кислота или ее соль по п.1 полезная в качестве противомикробного лекарственного средства.2.1- (6-amino-3,5-difluoropyridin-2-yl) -8-bromo-7- (3-ethylaminoazetidin-1-yl) -6-fluoro-4-oxo-1,4-dihydroquinoline- 3-carboxylic acid or its salt according to claim 1 is useful as an antimicrobial drug. 3. Противомикробная лекарственная композиция, включающая 1-(6-амино-3,5-дифторпиридин-2-ил)-8-бром-7-(3-этиламиноазетидин-1-ил)-6-фтор-4-оксо-1,4-дигидрохинолин-3-карбоновую кислоту или ее соль и фармацевтически приемлемый носитель.3. Antimicrobial drug composition comprising 1- (6-amino-3,5-difluoropyridin-2-yl) -8-bromo-7- (3-ethylaminoazetidin-1-yl) -6-fluoro-4-oxo-1 , 4-dihydroquinoline-3-carboxylic acid or its salt and a pharmaceutically acceptable carrier. 4. Применение 1-(6-амино-3,5-дифторпиридин-2-ил)-8-бром-7-(3-этиламиноазетидин-1-ил)-6-фтор-4-оксо-1,4-дигидрохинолин-3-карбоновой кислоты или ее соли в качестве противомикробного лекарственного средства.4. Use of 1- (6-amino-3,5-difluoropyridin-2-yl) -8-bromo-7- (3-ethylaminoazetidin-1-yl) -6-fluoro-4-oxo-1,4-dihydroquinoline -3-carboxylic acid or its salt as an antimicrobial drug. 5. Способ лечения инфекционных заболеваний, включающий введение 1-(6-амино-3,5-дифторпиридин-2-ил)-8-бром-7-(3-этиламиноазетидин-1-ил)-6-фтор-4-оксо-1,4-дигидрохинолин-3-карбоновой кислоты или ее соли.5. A method of treating infectious diseases, including the introduction of 1- (6-amino-3,5-difluoropyridin-2-yl) -8-bromo-7- (3-ethylaminoazetidin-1-yl) -6-fluoro-4-oxo -1,4-dihydroquinoline-3-carboxylic acid or a salt thereof.
RU2002102491/04A 1999-07-01 2000-06-22 1-(6-amino-3,5-difluoropyridine-2-yl)-8-bromo-7-(3-ethylaminoazethidine-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, medicinal composition and method for treatment based on this compound RU2236408C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11/187492 1999-07-01
JP18749299 1999-07-01

Publications (2)

Publication Number Publication Date
RU2002102491A true RU2002102491A (en) 2003-11-27
RU2236408C2 RU2236408C2 (en) 2004-09-20

Family

ID=16207019

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002102491/04A RU2236408C2 (en) 1999-07-01 2000-06-22 1-(6-amino-3,5-difluoropyridine-2-yl)-8-bromo-7-(3-ethylaminoazethidine-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, medicinal composition and method for treatment based on this compound

Country Status (25)

Country Link
US (1) US6858625B1 (en)
EP (1) EP1193266B1 (en)
JP (1) JP3477465B2 (en)
KR (1) KR100628414B1 (en)
CN (1) CN1157389C (en)
AT (1) ATE248162T1 (en)
AU (1) AU766014B2 (en)
BR (1) BR0012192A (en)
CA (1) CA2376760C (en)
CZ (1) CZ302033B6 (en)
DE (1) DE60004846T2 (en)
DK (1) DK1193266T3 (en)
ES (1) ES2206257T3 (en)
HK (1) HK1047103B (en)
HU (1) HUP0201549A3 (en)
IL (2) IL147043A0 (en)
MX (1) MXPA02000103A (en)
NO (1) NO321803B1 (en)
NZ (1) NZ516201A (en)
PT (1) PT1193266E (en)
RU (1) RU2236408C2 (en)
SK (1) SK285814B6 (en)
TW (1) TW576832B (en)
WO (1) WO2001002390A1 (en)
ZA (1) ZA200110357B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02002220A (en) 1999-09-02 2002-09-02 Wakunaga Pharma Co Ltd Quinolinecarboxylic acid derivative or its salt.
US7172535B2 (en) * 2004-10-28 2007-02-06 Volmar John F Upper back exercise machine and method of use
KR20070084159A (en) * 2004-11-17 2007-08-24 와쿠나가 세이야쿠 가부시키 가이샤 New pyridonecarboxylic acid derivatives or salts thereof
EP3214083B1 (en) * 2008-09-24 2020-09-16 Melinta Subsidiary Corp. Process for making quinolone compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548664B1 (en) * 1983-07-06 1986-03-21 Provesan Sa 7- (PYRROL-L-YL) DERIVATIVES OF L-ETHYL-1,4-DIHYDRO-4-OXOQUINOLEIN-3-CARBOXYLIC ACIDS AND L-ETHYL-1,4-DIHYDRO-4-OXO- (1,8-NAPHTYRIDINE) ) -3-SUBSTITUTED CARBOXYLICS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
NO177302C (en) * 1989-03-16 1995-08-23 Esteve Labor Dr Analogous Process for Preparing Therapeutically Active Substituted Azetidinyl Quinolone (Naphthyridone) Carboxylic Acid Derivatives
JP2758722B2 (en) 1993-08-13 1998-05-28 ドング ホワ ファーマシューチカル インダストリアル カンパニー，リミテッド New quinolone carboxylic acid derivatives
WO1996012704A1 (en) * 1994-10-20 1996-05-02 Wakunaga Seiyaku Kabushiki Kaisha Novel pyridonecarboxylate derivative or salt thereof and antibacterial containing the same as active ingredient
CN1105715C (en) * 1995-09-22 2003-04-16 涌永制药株式会社 Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing them as active ingredients
WO1997040036A1 (en) 1996-04-19 1997-10-30 Wakunaga Pharmaceutical Co., Ltd. Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing the same as the active ingredient
WO1998023592A1 (en) 1996-11-28 1998-06-04 Wakunaga Pharmaceutical Co., Ltd. Novel pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
DE19652239A1 (en) * 1996-12-16 1998-06-18 Bayer Ag Use of 7- (2-oxa-5,8-diazabicyclo [4.3.0] non-8-yl) -quinolone and naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and the associated gastroduodenal diseases
JPH11292873A (en) 1998-04-07 1999-10-26 Dainippon Pharmaceut Co Ltd Method for producing quinolone carboxylic acid derivative and intermediate thereof

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