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RU2000100940A - FILMED TABLET OF IMPROVED SAFETY FOR THE UPPER DEPARTMENTS OF THE GASTROINTESTINAL TRACT - Google Patents

FILMED TABLET OF IMPROVED SAFETY FOR THE UPPER DEPARTMENTS OF THE GASTROINTESTINAL TRACT

Info

Publication number
RU2000100940A
RU2000100940A RU2000100940/14A RU2000100940A RU2000100940A RU 2000100940 A RU2000100940 A RU 2000100940A RU 2000100940/14 A RU2000100940/14 A RU 2000100940/14A RU 2000100940 A RU2000100940 A RU 2000100940A RU 2000100940 A RU2000100940 A RU 2000100940A
Authority
RU
Russia
Prior art keywords
dosage form
form according
preceding paragraphs
active ingredient
specified
Prior art date
Application number
RU2000100940/14A
Other languages
Russian (ru)
Other versions
RU2193880C2 (en
Inventor
Ричард Джон ДАНСЕРО
Петрус Якобус БЕККЕР
Original Assignee
Дзе Проктер Энд Гэмбл Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Проктер Энд Гэмбл Компани filed Critical Дзе Проктер Энд Гэмбл Компани
Publication of RU2000100940A publication Critical patent/RU2000100940A/en
Application granted granted Critical
Publication of RU2193880C2 publication Critical patent/RU2193880C2/en

Links

Claims (10)

1. Новая пероральная лекарственная форма, подлежащая доставке в желудок, причем указанная лекарственная форма включает безопасное и эффективное количество активного ингредиента, выбранного из группы, включающей антибиотики тетрациклиновой группы, препараты железа, хинидин, нестероидные противовоспалительные средства, алпренолол, аскорбиновую кислоту, каптоприл, теофиллин, зидовудин, бисфосфонаты или их смеси и фармацевтически приемлемые наполнители, где указанная пероральная лекарственная форма характеризуется обычно овальной формой и пленочным покрытием для облегчения быстрого прохождения через пищевод и предупреждения раздражения в ротовой полости, преддверии рта, глотке и пищеводе.1. A new oral dosage form to be delivered to the stomach, said dosage form comprising a safe and effective amount of an active ingredient selected from the group consisting of tetracycline antibiotics, iron preparations, quinidine, non-steroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline , zidovudine, bisphosphonates or mixtures thereof and pharmaceutically acceptable excipients, wherein said oral dosage form is typically oval shaped oh and film coated to facilitate rapid passage through the esophagus and preventing irritation in the mouth, buccal cavity, pharynx and esophagus. 2. Лекарственная форма по п.1, где указанное пленочное покрытие растворимо при рН от 1,2 до 5. 2. The dosage form according to claim 1, where the specified film coating is soluble at a pH of from 1.2 to 5. 3. Лекарственная форма по п.1 или 2, где указанное пленочное покрытие выбрано из группы, включающей гидроксипропилметилцеллюлозу, гидроксипропилцеллюлозу, карбоксиметилцеллюлозу, метилцеллюлозу, этилцеллюлозу, полиакрилат, поливинилпирролидон или желатин или их смеси. 3. The dosage form according to claim 1 or 2, wherein said film coating is selected from the group consisting of hydroxypropyl methyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, methyl cellulose, ethyl cellulose, polyacrylate, polyvinylpyrrolidone or gelatin, or mixtures thereof. 4. Лекарственная форма по любому из предыдущих пунктов, где указанная лекарственная форма обладает следующими размерами от 0,23 до 0,85 дюймов длиной, от 0,11 до 0,4 дюймов шириной и от 0,075 до 0,3 дюймов толщиной. 4. The dosage form according to any one of the preceding paragraphs, where the specified dosage form has the following dimensions from 0.23 to 0.85 inches long, from 0.11 to 0.4 inches wide and from 0.075 to 0.3 inches thick. 5. Лекарственная форма по любому из предыдущих пунктов, где указанная лекарственная форма имеет модифицированную овальную или каплевидную форму. 5. The dosage form according to any one of the preceding paragraphs, where the specified dosage form has a modified oval or teardrop shape. 6. Лекарственная форма по любому из предыдущих пунктов, где указанный активный ингредиент выбран из группы, включающей эмперонийбромид, доксициклин, препараты железа, хлорид калия, хинидин, нестероидные противовоспалительные средства, алпренолол, аскорбиновую кислоту, каптоприл, теофиллин, зидовудин, ризедронат, алендронат или памидронат или их смеси. 6. A dosage form according to any one of the preceding paragraphs, wherein said active ingredient is selected from the group consisting of emperonium bromide, doxycycline, iron preparations, potassium chloride, quinidine, non-steroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovudine, risedronate, alizedronate pamidronate or mixtures thereof. 7. Лекарственная форма по любому из предыдущих пунктов, где указанный активный ингредиент выбран из группы, включающей ризедронат, алендронат или памидронат. 7. A dosage form according to any one of the preceding paragraphs, wherein said active ingredient is selected from the group consisting of risedronate, alendronate or pamidronate. 8. Лекарственная форма по любому из предыдущих пунктов, где указанная лекарственная форма содержит ризедронат в количестве от 0,25% до 40% композиции. 8. The dosage form according to any one of the preceding paragraphs, where the specified dosage form contains risedronate in an amount of from 0.25% to 40% of the composition. 9. Новая пероральная лекарственная форма по любому из предыдущих пунктов, где указанная лекарственная форма является спрессованной таблеткой, включающей частицы активного ингредиента и фармацевтически приемлемые наполнители. 9. The new oral dosage form according to any one of the preceding paragraphs, where the specified dosage form is a compressed tablet comprising particles of the active ingredient and pharmaceutically acceptable excipients. 10. Новая пероральная лекарственная форма по любому из предыдущих пунктов, где указанные частицы активного ингредиента сами покрыты пленкой. 10. The new oral dosage form according to any one of the preceding paragraphs, where these particles of the active ingredient are themselves coated with a film.
RU2000100940/14A 1997-06-11 1998-06-08 Film-covered tablet of improved safety for upper departments of gastrointestinal tract RU2193880C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4930697P 1997-06-11 1997-06-11
US60/049,306 1997-06-11

Publications (2)

Publication Number Publication Date
RU2000100940A true RU2000100940A (en) 2001-10-20
RU2193880C2 RU2193880C2 (en) 2002-12-10

Family

ID=21959131

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000100940/14A RU2193880C2 (en) 1997-06-11 1998-06-08 Film-covered tablet of improved safety for upper departments of gastrointestinal tract

Country Status (29)

Country Link
US (4) US6165513A (en)
EP (1) EP0989848B1 (en)
JP (3) JP5093937B2 (en)
KR (1) KR100400053B1 (en)
CN (1) CN1274279A (en)
AR (1) AR027158A1 (en)
AT (1) ATE277606T1 (en)
AU (1) AU729912B2 (en)
BR (1) BR9810027A (en)
CA (1) CA2293815C (en)
CO (1) CO4940409A1 (en)
DE (1) DE69826660T2 (en)
DK (1) DK0989848T3 (en)
ES (1) ES2226128T3 (en)
HU (1) HUP0004625A1 (en)
IL (2) IL133405A0 (en)
MY (1) MY127526A (en)
NO (1) NO996116L (en)
NZ (1) NZ503946A (en)
PE (1) PE82999A1 (en)
PL (1) PL337813A1 (en)
PT (1) PT989848E (en)
RU (1) RU2193880C2 (en)
SG (1) SG108292A1 (en)
SK (1) SK284690B6 (en)
TR (1) TR200000111T2 (en)
TW (1) TW542725B (en)
WO (1) WO1998056360A2 (en)
ZA (1) ZA985010B (en)

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