RU175147U1 - UNIVERSAL SPECTROMETER SAMPLE HOLDER - Google Patents

Abstract

This utility model relates to nozzles and holders for test samples used in spectrometry. The problem the utility model is aimed at is the development of a universal sample holder for research in Raman spectrometers, which allows analyzing substances directly in the ampoule of the original preparation without using vials or cuvettes. The universal sample holder for the spectrometer contains a nozzle, a screw-threaded table, a stud, a spring, a clamp, a clamping nut, and the nozzle has a slot through which the sample is irradiated with a laser or other excitation source, the nozzle also has a stud slot and a through hole, with one the side of which is a screw thread for screwing the table. The holder also includes a light shield. 1 s.p. f-ly, 6 ill.

Description

This utility model relates to nozzles and holders for test samples used in spectrometry.

A holder for an optical instrumental analysis system is known from the prior art (US patent US 3806259 (A) from 04/23/1974, IPC: G01J 3/02; G01N 21/25; G01N 1/10; G01N 21/16, Holder unit for optical instrumental analysis system). This patent describes a sample holder in an optical instrumental analysis system. The holder is designed to use a ditch, as well as other kinds of samples using a special unit. The disadvantages of this holder are:

1. Limited block size for samples. It is not possible to use various shapes and sizes of containers for analysis.

2. There is no way to select a specific position of the sample in the holder, to adjust it in height.

3. A special cover acts as a light-shielding screen. In the case of using samples higher than the height of the holder, the use of this cover will be impossible.

4. The holder is located inside the device, which does not provide information on the exact position of the sample in the holder.

Closest to the claimed technical solution is the installation with several rotating test containers for Raman spectroscopy (US patent US 2014118733 (A1) dated 05/01/2014, IPC: G01N 1/00; G01N 21/65 Multiple-Vial, Rotating Sample Container Assembly for Raman Spectroscopy). A rotating container is described having at least two openings formed therein, each opening being configured to hold an ampoule containing the test material. The holes are arranged so that when the container rotates, the ampoules inside the holder are alternately located on the path of the laser beam, Raman scattering from each sample is collected during the same measurement period. The rotation of the container is fast enough, so that the sample in each vial is measured many times during the entire analysis period. For quantitative comparison, one vial contains a reference sample. It can be a pure substance, a substance diluted in a solvent (eg water), or a mixture of substances. Another vial contains the sample to be evaluated. The disadvantages of this holder are:

1. The fixed diameter of the hole for the vial. This necessitates the use of standard vials for analysis of samples of appropriate sizes.

2. The use of ampoules of drugs of different diameters, different from the diameter of the holes for this installation, can lead to the results of insufficient accuracy and reproducibility due to the impossibility of sufficient fixation of the samples.

3. It is not possible to select a specific position of the sample in the holder.

4. Samples are analyzed through the bottom of the vial. This can cause distortion of the obtained spectra as a result of radiation refraction when using containers with excellent bottom curvature.

5. It is not possible to analyze samples having a curved shape of the package (for example, the upper sealed part of the ampoule).

6. The cover of the vial acts as a light shield. In the case of using samples of a different type (ampoules, vials, syringes, cartridges), the possibility of protection from daylight during analysis is not provided.

Thus, for each of the holders of the presented patents, a number of disadvantages are characteristic. They are not suitable for the task of non-destructive analysis of drugs, since they require the use of standard vials / cuvettes. The data of the invention do not allow analysis from ampoules, placing them with the upper sealed part down. They are not intended for the analysis of syringes and cartridges for them, various kinds of bottles.

The task to which the invention is directed is the development of a universal sample holder for research in Raman spectrometers, which allows the analysis of substances directly in the ampoule of the original drug, without using vials or cuvettes.

This problem is solved due to the fact that the claimed universal sample holder for the spectrometer contains a nozzle, a table with a screw thread, a pin, a spring, a clamp, a clamping nut, while the nozzle has a slot through which the sample is irradiated with a laser or other excitation source, the nozzle also has slot for studs and a through hole, on one side of which there is a screw thread for screwing the table. The holder also includes a light shield.

The essence of the utility model is illustrated by drawings, which depict:

in FIG. 1 - view of the holder in disassembled and assembled condition;

in FIG. 2 - General view of the holder assembly;

in FIG. 3-side view of the holder;

in FIG. 4 - direct placement of the sample in the holder;

in FIG. 5 - reverse vertical position of the sample in the holder;

in FIG. 6 - reverse or direct vertical position without using a table.

The universal sample holder for the spectrometer contains a nozzle 1, a table 2 (with a screw thread), a stud 3, a spring 4, a clamp 5, a clamping nut 6, a light-shielding cover 7. The nozzle has a slot through which the sample is irradiated with a laser or other excitation source, a slot for studs and a through hole, on one side of which there is a screw thread for screwing the table.

The holder is assembled as follows. In the nozzle hole, insert the pin with the hat out. A spring is put on the stud inside the nozzle. Connect the stud and clamp with the convex side inside the nozzle. Put a clamping nut on the nozzle. Screw the table into the bottom of the threaded nozzle (if necessary). Attach the nozzle to the device using the clamping nut.

The holder is used to fix ampoules, vials, vials, cartridges and syringes of drugs with a diameter of up to 20 mm using a Raman spectrometer during analysis.

The device is used as follows.

The sample is placed in the upper hole of the nozzle and fixed so that the clean surface of the glass / plastic (without a label and the marking) of the ampoule, vial or other package is at the level of the emitter gap. The container of the drug is fixed with a clamp. The table is screwed on / off to the required height so that the sample is on the table at the appropriate level. If necessary, the nozzle can be used without a table. During the analysis, the nozzle is completely closed with a light-protective casing.

There are various options for placing the sample in the nozzle:

- Direct position. The sample is installed on the table bottom-down, fixed with a clamp, (Fig. 4)

- The reverse vertical position from the breakable part. The sample is installed in the nozzle breakable part down on the table, fixed with a clamp (Fig. 5).

- Reverse or direct vertical position without using a table. The sample is fixed in the nozzle clip. The table is not used (Fig. 6).

Thus, the holder of the studied samples for the spectrometer according to this utility model makes it possible to use various shapes and sizes of containers for analysis, makes it possible to select a specific position of the sample in the holder, and adjust its height.

Claims (2)

1. A universal sample holder for the spectrometer, containing a nozzle, a screw-threaded table, a stud, a spring, a clamp, a clamping nut, the nozzle having a slot through which the sample is irradiated with a laser or other excitation source, the nozzle also has a stud slot and a through hole , on one side of which there is a screw thread for screwing the table. 2. The universal sample holder for the spectrometer according to claim 1, characterized in that it contains a light-shielding casing.

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