RS20140628A1 - MOBILE SYSTEM FOR MEASUREMENT OF ELECTROPHYSIOLOGICAL SIGNALS BY A PORTABLE DEVICE WITH AN INTEGRATED MODULE FOR CONNECTION WITH CENTRAL SERVER BY INTERNET CONNECTION - Google Patents

Abstract

The present invention relates to a system for measuring electrophysiological signals using a portable device for recording and sending recorded signals to central and sending recorded signals, central server, central database, devices for processing, displaying and storing electrophysiological signals in remote centers, processing devices, display and storage of electrophysiological signals located near a recording device, a control device that controls a recording and sending signal, such as a central server, a central database and devices for processing, displaying and storing electrophysiological signals located in remote centers connected to the Internet or other wireless digital communications network for remote signal transmission.

Description

M o&/U/jSystem for measuring electrophysiological signals portable

a device with an integrated module for connecting to

central server using an Internet connection

Description of the Invention

Technical field to which the invention relates:

The presented invention relates to a system for recording electrophysiological, primarily electroencephalographic (EEG), signals, a portable device for instantly sending recorded signals to a central system using the Internet or another network for wireless transmission of digital signals for further storage, processing, storage, analysis and/or display.

According to the International Patent Classification (IPC) the appropriate designation is: G06Q 50/00 and G06Q 90/00

Technical Problem:

The presented invention enables the measurement of electrophysiological, primarily electroencephalographic, signals and their immediate sending of recorded signals to a central server without the use of additional devices for recording and sending. Signals can be stored in a central database or forwarded to other devices for processing, storage, analysis and review. The signals can also be subsequently read from the central database and stored, processed, analyzed and viewed on other devices.

Description of the state of the art:

Although electroencephalographic (EEG) devices have been in use since the first half of the 20th century, the wider use of EEG recordings only began around 1990. This was primarily due to the development of digital recording devices, which enabled the use of computer algorithms for storing, reading, analyzing and processing recorded EEG signals.

With the advancement of electronics, EEG devices became smaller and smaller, until they finally became small enough in size to allow their use as completely mobile and portable systems. Such devices are the Epoc system by Emotiv, the Smarting system by mBrainTrain, the Nautilus and Sahara systems by G-Tec, and others. These devices typically contain wireless transmitters and send recorded signals to other devices, such as personal and portable computers or mobile ("smart") phones, where further processing is usually performed.

This setup allows subjects whose EEG signals are being acquired (in the case of scientific experiments) or patients (in the case of medical imaging) to gain freedom of movement. This, in addition to comfort, enabled a significantly wider range of possible uses for these EEG devices, which primarily stem from the recording paradigm outside the laboratory or ambulatory environment.

In addition to the mentioned applications, there is a need for mobile (wearable) EEG devices that have the possibility of direct communication with the central server system. Existing patents assume the possibility of communication between a computer or mobile phone and a central server. However, the advantages of direct connection to the central server using the built-in module for direct connection to the central server and the central database via the Internet are obvious.

Several patents and scientific papers involve the recording of EEG signals, via a mobile phone or computer.

US 20070255127 Al presents a system for recording and storing recorded electroencephalographic signals in a central database. However, the recorded data is sent from the recording device via a wireless connection to a device located near the recording device, and only then is it indirectly sent via the Internet and stored in a central database.

US 20130127708 Al presents a system for recording electroencephalographic signals with feedback. The recording device also communicates wirelessly via Bluetooth with nearby devices (computer or phone) and provides the possibility of internal processing. However, this system does not provide for communication with a central server of a non-local nature.

US 6654633 B2 describes a system for sending a recorded electrophysiological (neurophysiological) signal over a long distance. However, this patent rests on the assumption that the signal is sent analogically recorded without digitization, which can easily lead to losses in the quality of the recorded signal. Also, the robustness of the communication link is debatable.

US 6052619A is one of the first disclosures of wireless EEG amplifiers which generally describes a device for recording, processing and sending a recorded EEG signal using a remote antenna including a number of analysis modules. However, the use of a screen, input method (keyboard) and printer on the device itself, as envisaged in the patent, would make the device bulky and therefore would not fall within the description of a wearable device. This invention envisages that the device for recording and sending the electrophysiological signal contains only systems for acquisition, analog-to-digital (A/D) conversion, software applications for signal processing, and modules for wireless transmission, so that the size and weight of the device remain small and portable. Also, the 6052619 A patent provides for sending only digital information obtained from an already processed signal, not a raw (unprocessed) signal as provided by our invention. The benefit of sending the raw recorded signal would be that the controllers using the device to store, process and display the signal could independently choose the processing techniques and display of the signal sent in this way. Furthermore, the 6052619 patent does not provide for a central server and a central database for storing signals. This approach would allow reprocessing the same raw signals and training new signal processing algorithms, in the future when such new algorithms are proposed.

US 8111151B2 describes a system for wireless transmission and early warning and communication with a central server. As in the previous cases, the device for the acquisition of electrophysiological signals in this case has only the possibility of short-range wireless communication with a mobile phone or other external device through which it accesses the Internet.

Each of the mentioned inventions either proposes short-haul data transmission, or long-distance analog data transmission, which accordingly requires additional equipment. The invention as proposed in this text implies a small system, easy to use, and high efficiency and the ability to transmit the recorded neurophysiological signal over a long distance. The proposed method of sending and storing data enables the development of future advanced systems for analyzing this data, because the original physiological character of the signal does not change.

Presentation of the Essence of the Invention:

The present invention provides a mobile system for recording, transmitting and storing electrophysiological signals, such as, but not limited to, electromyogram (EMG), electrocardiogram (ECG) and electroencephalogram (EEG).

Analogue electrophysiological signals are recorded using an unspecified number of electrodes that adhere to the subject's or patient's skin. The signals are fed from the electrodes by a conductive, electrically shielded wire to the input low-pass filter, in order to then amplify and multiplex the signal. The multiplexed signal is then fed to the inputs of the analog-to-digital converter and the output digital signals are obtained. By using high-precision analog-digital converters, and by reducing the distance between the recording site (electrode) and the acquisition device that is very close to the head or in contact with it, it is possible to record EEG signals, which are otherwise of very low amplitude and were almost impossible to record without the use of preamplifiers and amplifiers.

This digital signal is further fed to an integrated module for wireless digital signal transmission (e.g. GPRS) and the signal is further sent via the existing infrastructure (e.g. Internet network) to a central server physically present in the central unit or distributed on the Internet network

- the so-called "cloud" system.

In addition, the central system enables connection with devices or computer programs for storing, processing and displaying signals located in remote centers, which can further access the signals stored in the central database and directly read them on monitors, or save them on a hard (hard) disk or any other form of media for storing digital records.

Therefore, the main subject of this invention is a mobile device for recording, transmitting, storing, processing and displaying electrophysiological signals and their long-range wireless transmission using digital transmission methods through existing infrastructure, such as e.g. GPRS network, to the central server for further processing and storage in the central database.

Another subject of the present invention is a mobile device for recording electrophysiological signals and their short-range wireless transmission, such as, but not limited to, Bluetooth or WiFi modules to further processing and display devices located near the recording device.

The third subject of this invention is a method of sending recorded electrophysiological signals to a central server by a recording device and sending electrophysiological signals in the form of digital data and storing recorded electrophysiological signals in a central database by a central server.

The fourth object of this invention is a method for displaying, processing and storing recorded electrophysiological signals in remote centers that are already stored in a central database, using a central server, a central database and a device for displaying, processing and storing recorded electrophysiological signals in remote centers.

A fifth object of the present invention is a method for displaying, processing and storing electrophysiological signals at remote centers in real time using an electrophysiological signal recording and processing device and a central server.

A sixth object of the present invention is a method for displaying, processing and storing electrophysiological signals near a device for recording and sending electrophysiological signals.

The need for the system proposed by this invention mainly (although there are other applications) arises in remote intensive care centers where patients are referred after severe bodily injuries, which very often include head injuries. These centers often do not have a trained neurologist on site who could, by examining the EEG recordings, draw adequate conclusions and establish a diagnosis or suggest a further course of treatment for the patient. units or from different units that have remote access to the central server, would significantly contribute to the quality of examination, diagnosis and, in emergency cases, adequate further steps of medical treatment.

In a different embodiment, the proposed system is applied for continuous monitoring of EEG signals in home conditions in real time, with or without an automatic measurement analysis system. In that case, the permanent residence of the monitored patient (his private house) would be the remote center. If the use of automatic signal marking is foreseen as part of the system, say for the purpose of diagnosing a disorder such as epilepsy, then such a system would bring several advantages: longer monitoring without increasing the cost of the engagement of medical staff, a more realistic review of the patient's condition due to being in a natural (home) environment, the engagement of a doctor "as needed" (say after the initiation of an epileptic attack) and others.

One or only a part or all of the total and other features and advantages of said invention will be readily apparent to those of skill in the art from the following description in which a preferred embodiment of the invention is shown and described, by simply illustrating one of the most convenient modes of carrying out the invention. As can be seen, the invention has various embodiments, and its several details can be changed to quite different obvious aspects without departing from the invention. Accordingly, the drawings and descriptions should be viewed as illustrative and not restrictive.

Short Description of the Picture:

FIGURE 1 is a schematic representation of the state of the technique, i.e. the classical system that is used today for the acquisition of electrophysiological signals.

FIGURE 2 is a schematic representation of a system consisting of a mobile device for recording and sending electrophysiological signals and communications with a central server, database and devices for recording and displaying signals (computers and mobile devices).

FIGURE 3 is an embodiment showing a flow diagram of a method of controlling a device for recording and sending electrophysiological signals by a device for controlling a device for recording and sending electrophysiological signals.

FIG. 4 is an embodiment showing the flow chart of the method of sending the recorded electrophysiological signals to the central server by the device for recording and sending the electrophysiological signals in the form of digital data and storing the recorded electrophysiological signals in the central database by the central server.

FIG. 5 is an embodiment showing a flow diagram of a method for displaying, processing and storing recorded electrophysiological signals in remote centers that are already stored in a central database, using a server, a central database and a device for displaying, processing and storing recorded electrophysiological signals in remote centers.

FIGURE 6 is an embodiment showing a flow diagram of a method for displaying, processing and storing electrophysiological signals at remote centers in real time using an electrophysiological signal recording and processing device and a central server.

FIGURE 7 is an embodiment showing a flow diagram of a method for displaying, processing and storing electrophysiological signals in proximity to a device for recording and sending electrophysiological signals.

Detailed Description of Desired Performance:

FIGURE 2 presents a schematic illustration showing a mobile system for recording, transmitting, storing, processing and displaying electrophysiological signals. The mobile system for recording, wireless transmission of downloaded digitized data over a distance using the existing infrastructure (Internet), storage, processing and displaying of electrophysiological signals includes electrodes that adhere to the skin of a patient or subject 21, a cap that holds the electrodes together and has a connector for a recording device 22, a device for recording and sending electrophysiological signals 23, a central server 24, a central database 25, devices for storing, displaying and processing recorded signals located near the recording device 26 and devices for storing, displaying and processing recorded signals located in remote centers 27. The device for recording and sending electrophysiological signals is further indicated by the fact that it is controlled by the control device 28. is an input system for receiving signals from an electrode, an amplifier, multiplexer and analog-to-digital (A/D) converter circuit 23b, a basic signal processing circuit 23c, a short-range wireless communication module such as WiFi or Bluetooth 23d and a long-range wireless communication module such as a GPRS module 23e. to send the recorded electrophysiological signals in digital form to devices for storing, processing and displaying signals located near the recording device 26. The device for recording and sending electrophysiological signals 23 is further characterized in that, by means of the long-range wireless communication module 23e, it can send the recorded electrophysiological signals together with metadata in digital form to a central server 24 via the Internet. The central server 24 is characterized in that it can receive recorded data from the recording device 23 and store them in central database 25 or sends them directly to devices for storing, processing and displaying recorded signals located in remote centers 27. The central server 24 is further characterized in that it can read the data stored in the central database 25 and forward it to devices for storing, processing and displaying signals located in remote centers 27. electrophysiological signals 23 using a short-range wireless communication module, such as Bluetooth or WiFi Direct23d and store the recorded signals in internal memory, or display them on a display monitor, after possibly having previously processed them with signal processing software applications. The signal storage, processing and display devices located near the recording device 26 are further indicated that they may have a display monitor and storage memory and may be controlled by a controller. They are further indicated that they must to have the possibility of wireless connection short range (such as, but not limited to WiFi Direct or Bluetooth). Devices for storing, processing and displaying signals located in remote centers 27 are indicated in that they can receive signals sent from the central server 24 using a long-range wireless communication module (e.g., the Internet) and store the recorded signals in internal memory, or display them on a display monitor, having previously possibly processed them with signal processing software applications. The signal storage, processing and display devices located at the remote centers 27 are further characterized in that they may have a display monitor and storage memory and may be controlled by a controller. They are further specified by the fact that they must have the ability to have long-range wireless connectivity (eg Internet access). The control device 28 is indicated by being connected to the device for recording and sending electrophysiological signals 23 by any connection (wired or wireless) and having the ability to enter meta data that the device for recording and sending 28 further sends to the central server. Meta data is entered into the control device by a software application.

FIGURE 3 represents a flow diagram of the way in which the control device controls the device for recording and sending electrophysiological signals. The control device is necessary to give commands to the device for recording and sending electrophysiological signals, necessary for the recorded data to be appropriately stored either in a central database or displayed, processed or stored on storage, processing and display devices located near the recording device or in remote centers. The control device is controlled by a trained controller.

At step 311, the control device is connected to the recording device using a wired or wireless connection.

At step 312, the controller, using a software application on the controller device, enters the identification of the patient or subject. The identification can only be an identification number, or an alphanumeric string or string of characters.

At step 313, the controller enters metadata that is of interest to the subject or patient being imaged. Meta data may, without limitation, include first name, last name, age, gender, time of recording, location and other data relevant to the recorded data.

At step 314, the controller selects whether the recording is sent to the central server, or sent to a signal display, processing and storage device located near the recording device, which is also a control device.

Further steps depend on how the system is implemented and are described in the following figures

FIG. 4 is a flow diagram of the method of sending the recorded electrophysiological signals to the central server by the device for recording and sending the electrophysiological signals in the form of digital data and storing the recorded electrophysiological signals in the central database by the central server. This flow continues to the flow diagram of Figure 3, when the controller at step 314 has made the selection to send the recorded signals to the central server.

At step 411, the control device sends a command to the recording device to turn on the long-range wireless communication module and to connect to the central server over the Internet.

At step 412, the control device via the sending device sends meta data to the central server to prepare the central server to accept further electrophysiological signals sent by the recording and sending device.

At step 413, the central server stores the metadata in the central database and prepares it to store the expected electrophysiological signals expected from the recording device and send the electrophysiological signals to the central server.

At step 414, when the connection to the central server is established, the control device sends a command to the recording device to start recording the electrophysiological signals and continuously sending them to the central server using the Internet.

At step 415, the central server continuously stores the recorded signals sent by the recording device and sends the electrophysiological signals to the central database.

At step 416, when the controller of the device for controlling the device for recording and sending electrophysiological signals entered a request to stop recording, the control device sends a request to stop recording to the device for recording and sending electrophysiological signals, it stops recording and sends a message to the central server that the recording has been stopped. The central server stops writing to the central database.

FIGURE 5 is a flow diagram of a method for displaying, processing and storing recorded electrophysiological signals in remote centers that are already stored in a central database, using a server, a central database and a device for displaying, processing and storing recorded electrophysiological signals in remote centers.

At step 511, the controller of the device for storing, processing and displaying the recorded electrophysiological signals in the remote centers enters the identifier of the recorded patient or subject whose data it wants to access in the central database.

At step 512, the device for storing, processing and displaying the recorded electrophysiological signals at the remote centers sends the patient or subject identifier to the central server and a request for data access.

At step 513, the central server retrieves the stored signals from the central database based on the patient or subject identifier, and sends the retrieved data to a device for storing, processing and displaying electrophysiological signals at remote centers.

At step 514, the electrophysiological signal processing and display storage device at the remote centers stores the retrieved signals in internal memory.

At step 515, the controller of the electrophysiological signal storage, processing, and display device at the remote centers may select to display the stored signals.

At step 516, the electrophysiological signal processing and display device displays the processed signals at the remote centers.

At step 517, the controller of the electrophysiological signal processing and display device controller at the remote centers may choose to save the processed signals.

Steps 515, 516 and 517 may be repeated an indefinite number of times.

FIGURE 6 is a flow diagram of a method for displaying, processing, and storing electrophysiological signals at remote centers in real time using an electrophysiological signal recording and sending device control device, an electrophysiological signal recording and sending device, and a central server. Step 611 is a continuation of step 314 of Figure 3, when the controller has chosen to send the recorded electrophysiological signals to the central server.

At step 611, the electrophysiological signal recording and sending device control device sends a request to the electrophysiological signal recording and sending device to enable a long range communication module, such as a GPRS module.

At step 612, the device for recording and sending electrophysiological signals sends metadata related to the patient or subject whose electrophysiological signals are being recorded to the central server.

At step 613, the central server writes the device identifier for recording and sending electrophysiological signals to the table of active devices.

At step 614, the electrophysiological signal storage, processing and display device sends to the central server the identifier of the electrophysiological signal recording and sending device whose recorded signals it wishes to access in real time.

At step 615, the central server verifies that the device identifier for recording and sending electrophysiological signals sent by the device for storing, processing and displaying electrophysiological signals at the remote centers is contained in the table of active devices. In case the identifier is not contained in the active device table, it goes directly to step 619, skipping steps 616, 617, 618.

At step 616, continuous recording of electrophysiological signals and their display on electrophysiological signal storage, processing and display devices at remote centers begins.

At step 617, the data can be continuously and cyclically stored, processed and displayed an indefinite number of times on devices for storing, processing and displaying electrophysiological signals at remote centers.

At step 618, the electrophysiological signal recording and sending device expects a signal to stop recording from the electrophysiological signal recording and sending device. If the signal has arrived, the recording is stopped.

At step 619, the central server deletes the device identifier for recording and sending electrophysiological signals from the table of active devices.

At step 620, the recording and transmission of electrophysiological signals is terminated.

FIGURE 7 is a flow diagram of a method for displaying, processing, and storing electrophysiological signals in proximity to a device for recording and sending electrophysiological signals. Step 711 is a continuation of step 314 of FIG. 3, where the controller has chosen to send the recorded electrophysiological signals to an electrophysiological signal storage, processing and display device located adjacent to the electrophysiological signal recording and sending device.

At step 711, since the controller has chosen to transmit the recorded electrophysiological signals locally, the control device sends a command to the recording device to turn on the short-range wireless communication module and to connect to a device for processing, storing and displaying the electrophysiological signals located near the recording device.

At step 712, when the connection to the signal processing, storage and display device is established, the control device sends a command to the recording device to start recording the electrophysiological signals and sending them to the device for storing, processing and displaying the recorded signals via a wireless Bluetooth or WiFi network.

At step 713, the data can be continuously and cyclically stored, processed, and displayed an indefinite number of times on devices for storing, processing, and displaying electrophysiological signals at remote centers.

At step 714, the device for recording and sending electrophysiological signals expects a signal to stop recording.

At step 715, recording is terminated.

In the description of the desired embodiment of the invention, the function of the control device (18) can also be performed by a device for storing, displaying and processing the recorded signals located near the recording device (16).

Devices for storing, displaying and processing signals, whether they are located near the recording device or in remote centers, can essentially be any mobile devices or computers or other devices that have, but are not limited to, the possibility of wireless communication (eg Bluetooth or WiFi), a monitor for displaying recorded signals, software applications for processing, memory for storing signals, the possibility of simultaneous communication with other devices that can be controlled, etc.

One skilled in the art will understand that the embodiment of the present invention as shown in the drawing figures and described above is merely a non-limiting example.

The foregoing description of a preferred embodiment of the present invention is presented for purposes of illustration and description. It is not intended to exhaust or limit the invention to the precise form or embodiments disclosed. Accordingly, the foregoing description should be viewed as illustrative rather than restrictive. Obviously, many modifications will be apparent to those skilled in the art. The embodiments have been selected and described so as to best explain the principles of the invention and the best ways to apply it, so as to enable those skilled in the art to understand the invention for various embodiments and various modifications, as appropriate to the particular use or intended application. The scope of the invention is intended to be defined by the appended claims and their equivalents, in which the terms are used in their broadest sense, unless otherwise indicated. It is to be understood the differences that may be made in embodiments of the invention as described by those skilled in the art, without departing from the scope of the invention described herein, as defined in the following claims. Moreover, no element or component in this description of the invention is intended for the public, regardless of whether the element or component is explicitly enumerated in the following claims.

Claims (67)

1. Mobile recording system, wireless transmission of downloaded digitized data using a wireless digital network, characterized in that it includes electrodes that adhere to the skin of the patient or subject (21), a cap that holds the electrodes together (22), a device for recording and sending electrophysiological signals (23), a central server (24), a central database (25), a device for controlling the device and recording and sending electrophysiological signals (28), devices for storing, displaying and processing recorded signals located near the recording device (26) and devices for storing, displaying and processing recorded signals located at remote centers (27) 2. A mobile system according to claim 1, characterized in that the electrodes that adhere to the skin of the patient or subject (21) are connected to a cap that holds the electrodes together (22), that the cap that holds the electrodes together is further connected to a device for recording and sending electrophysiological signals (23), that the device for recording and sending electrophysiological signals (23) is further connected to a central server (24) by means of a remote digital data transmission network, which is a central database (25) connected to the central server (24), which are devices for storing, displaying and processing recorded signals in remote centers (27) connected to the central server (24) by a network for the transmission of digital data at a distance, which is a device for recording and sending electrophysiological signals (23) connected to a device for controlling the device for recording and sending electrophysiological signals (28) by a wireless network for transmitting digital data. 3. Mobile system according to claim 1, characterized in that the electrodes that adhere to the skin of the patient or subject (21) are connected to a cap that holds the electrodes together (22), that the cap that holds the electrodes together is further connected to a device for recording and sending electrophysiological signals (23), that the device for recording and sending electrophysiological signals (23) is further connected to a device for controlling the device for recording and sending electrophysiological signals (28) by a wireless network for transmitting digital data, which are devices for storing, displaying and processing recorded signals located near the device for recording and sending electrophysiological signals [26] connected to the device for recording and sending electrophysiological signals (23) by a wireless network for the transmission of digital data. 4. A mobile system according to claims 1 and 2, characterized in that the network for long-distance digital data transmission is the Internet. 5. Mobile system according to claims 1-3, characterized in that the wireless network for transmitting digital data is a WiFi network. 6. Mobile system according to claims 1-3, characterized in that the wireless network for transmitting digital data is a Bluetooth network. 7. Mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals (23) contains a signal acquisition module (23a) which is an input system for receiving signals from electrodes 8. Mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals (23) contains an electric circuit or chip with an amplifier, multiplexer and analog-to-digital converter (23b). 9. Mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals (23) contains a signal processing circuit (23c). 10. Mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals (23) contains a short-range wireless communication module (23e). 11. A mobile system according to claims 1, 2, 3 and 10, characterized in that the short-range wireless communication module is a Bluetooth module. 12. A mobile system according to claims 1, 2, 3 and 10, characterized in that the short-range wireless communication module is a WiFi module. 13. Mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals contains a module for long-range wireless communication (23d). 14. The mobile system according to claims 1, 2, 3 and 13, characterized in that the long-range wireless communication module (23d) is a GPRS module. 15. A mobile system according to claims 1, 2, 3 and 13, characterized in that the long-range wireless communication module (23d) is a 3G module. 16. A mobile system according to claims 1-3, characterized in that the device for recording and sending electrophysiological signals (23) is controlled by the device for controlling the device for recording and sending electrophysiological signals (28). 17. Mobile system according to claims 1-3, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) has a module for entering recording metadata. 18. The mobile system according to claims 1, 2, 3 and 17, which is a touch screen recording metadata input module. 19. Mobile system according to requirements 1, 2, 3 and 17, indicated, which are the metadata of the patient's first and last name, age, gender, recording time. 20. Mobile system according to claims 1, 2, 3, 17 and 19, characterized in that the metadata is a patient identifier. 21. The mobile system according to claims 1, 2, 3, 17 and 19, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) has a screen for displaying metadata that is entered for control. 22. The mobile system according to claims 1-3, indicated by the device for controlling the device for recording and sending electrophysiological signals (28) is a programmable device. 23. The mobile system according to claims 1, 2, 3, 5 and 6, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) has a wireless communication module for the transmission of digital data. 24. Mobile system according to claims 1, 2, 3, 5, 6 and 23, characterized in that the wireless communication for the transmission of digital data is WiFi communication. 25. Mobile system according to claims 1, 2, 3, 5, 6 and 23, characterized in that the wireless communication for the transmission of digital data is Bluetooth communication. 26. Mobile system according to claims 1-3 and 17-25, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) is essentially a personal computer. 27. Mobile system according to claims 1-3 and 17-25, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) is essentially a tablet. 28. Mobile system according to claims 1-3 and 17-25, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) is essentially a mobile phone. 29. Mobile system according to claims 1-3, 5, 6 and 17-25, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) is essentially a programmable computer device. 30. Mobile system according to claims 1, 3, 5 and 6, characterized in that the device for storing, displaying and processing the recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) is connected to the device for recording and sending electrophysiological signals (23) by a wireless network for the transmission of digital data. 31. Mobile system according to claims 1, 3 and 30, characterized in that the device for storing, displaying and processing the recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains a screen for displaying the recorded electrophysiological signals. 32. The mobile system according to claims 1, 3 and 30, characterized in that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains a memory for storing recorded electrophysiological signals. 33. The mobile system according to claims 1, 3 and 30, characterized in that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains a memory for storing recorded electrophysiological signals. 34. The mobile system according to claims 1, 3, 30 and 33, characterized in that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains a short-range wireless communication module. 35. The mobile system according to the claims 1, 3, 30 and 33 indicated, that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains a module for wireless short-range communication. 36. The mobile system according to claims 1, 3, 30 and 35, characterized in that the short-range wireless communication module is a Bluetooth module. 37. A mobile system according to claims 1, 3, 30 and 35, characterized in that the short-range wireless communication module is a WiFi module. 38. Mobile system according to claims 1, 3 and 30-37, indicated, which is a device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) essentially a personal computer. 39. Mobile system according to claims 1, 3 and 30-37, characterized in that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) is essentially a tablet. 40. Mobile system according to claims 1, 3 and 30-37, characterized in that the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) is essentially a mobile phone. 41. The mobile system according to claims 1, 3 and 30-37, characterized in that the device for storing, displaying and processing the recorded electrophysiological signals located near the device for recording and sending the electrophysiological signals (26) is essentially a programmable computer device that has a screen, the ability to enter data, and a short-range wireless communication module. 42. Mobile system according to claims 1, 3 and 17-37, characterized in that the device for controlling the device for recording and sending electrophysiological signals (28) and the device for storing, displaying and processing recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) are essentially integrated into one device. 43. The method for storing the recorded electrophysiological data in the central database consists of: (a) Provision of a mobile system according to claims 1, 2, 4-12, 16-29. (b) Providing at least one controller that operates the device for controlling the device for recording and sending electrophysiological signals (28). (c) Entering the patient or subject identifier into the control device (312). (d) Entry of recording metadata, such as, but not limited to, patient's first and last name, age, gender, recording time (313). (e) Inputting the controller selection to the device for controlling the recording device and sending the electrophysiological signals to store the data in the central database (314). (f) Sending the meta data and selecting the controller to store the electrophysiological signals in the central database to the device for recording and sending electrophysiological signals (23) by the device for controlling the device for recording and transmitting electrophysiological signals (28). (g) Inclusion of a module for accessing a wireless network for the transmission of digital data (411), such as, but not limited to, the Internet. (h) Sending the meta data (412) to the central server (24) by the electrophysiological signal recording and transmission device (23). (i) Storing the meta data (413) in a central database (25) by a central server (24). (j) Sending a request for recording the electrophysiological signals belonging to the stored metadata to the central database (25) by the central server (24). (k) Sending confirmation of the prepared memory for storing the recorded electrophysiological signals belonging to the stored metadata to the central server (24) by the central database (25). (1) Sending confirmation that the central database (25) is ready to store the electrophysiological signals belonging to the stored metadata to the device for recording and sending the electrophysiological signals by the central server (24). (m) Initiation of recording (414) by the device for recording and sending electrophysiological signals (23). (n) Continuous recording of electrophysiological signals by a device for recording and sending electrophysiological signals (23) and sending them to a central server (24). (o) Continuous storage of the recorded electrophysiological signals (415) in the central database (25) by the central server (24) in the memory selected to store those electrophysiological signals depending on the entered meta data. (p) Entering a request to stop recording and sending electrophysiological signals (416) by the controller when the controller has decided that it wants to stop recording. (q) Sending a recording termination request to the electrophysiological signal recording and sending device (23) by the electrophysiological signal recording and sending device control device (28). (r) Sending a termination request to the central server (24) by the device for recording and sending electrophysiological signals (23). (s) Sending a request to terminate and stop storage in the central database (25) by the central server (24). (t) Sending a confirmation that the enrollment in the central database (25) has been terminated to the device for recording and sending electrophysiological signals (23) by the central server (24). (u) Interruption of electrophysiological signal recording (417) by electrophysiological signal recording and sending device (23). 44. Mobile system according to claims 1, 2, 4-12, 16-29, 43, characterized in that the meta data includes the identifier of the recorded patient or subject. 45. A method for displaying, processing and storing recorded electrophysiological signals in remote centers that are already stored in a central base consists of: (a) Providing a mobile system according to claims 1, 2, 4-12, 16-29, 43 144. (b) Providing at least one device controller for storing, processing and displaying recorded electrophysiological signals located in remote centers (27). (c) Entering the identifier of the patient or subject (511) in the device for storing, processing and displaying the recorded electrophysiological signals (27) of the recorded patient or subject whose meta data and recorded signals are stored in the central database (25) by the controller. (d) Sending the patient or subject identifier (512) to the central server (24) by the device for storing, processing and displaying the recorded electrophysiological signals at the remote centers (27) and requesting data download for the corresponding patient or subject. (e) Reading the meta data and recorded electrophysiological signals (513) from the central database (25) by the central server (24) based on the patient or subject identifier. (f) Sending the read meta data and the recorded electrophysiological signals from the central database (25) to the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the central server (24). (g) Storing the meta data and the recorded electrophysiological signals (514) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (h) Displaying the electrophysiological signals (515) on the screen of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (i) Using a software application for processing the recorded electrophysiological signals (516) on the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller (j) Storing the meta data and processed electrophysiological signals (517) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (k) Displaying the processed electrophysiological signals (515) on the screen of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (1) Processing (516), display (515) and storage of recorded signals (517) in devices for storing, processing and displaying recorded signals in remote centers (27), can be repeated continuously, cyclically and an indefinite number of times. 46. The mobile system according to claims 1, 2, 4-12, 16-29, 43, 44 and 45, characterized in that the meta data includes the identifier of the recorded patient or subject. 47. Mobile system according to claims The method according to claims 1, 2, 4-12, 16-29, 43-46, characterized in that the processing, display and storage of recorded meta data and processed electrophysiological signals can be performed cyclically, with an indefinite number of repetitions and in an indefinite order. 48. Mobile system according to claims 1, 2, 4 and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) contains a screen. 49. Mobile system according to claims 1, 2, 4 and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) contains a data input module. 50. Mobile system according to claims 1, 2, 4 and 43-47, 49, characterized in that the data input module is a touch screen. 51. Mobile system according to claims 1, 2, 4, and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) contains a memory for data storage. 52. Mobile system according to claims 1, 2, 4, and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) contains a module for remote digital data transmission. 53. A mobile system according to claims 1, 2, 5, 6, 43-47 and 52, characterized in that the module for long-distance digital data transmission is essentially a GPRS module. 54. Mobile system according to claims 1, 2, 4, 43-47 and 52, characterized in that the module for the transmission of digital data at a distance is essentially a 3G module. 55. Mobile system according to claims 1, 2, 4, and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) is essentially a personal computer. 56. Mobile system according to claims 1, 2, 4, and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) is essentially a portable computer. 57. Mobile system according to claims 1, 2, 4, and 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) is essentially a tablet. 58. Mobile system according to claims 1, 2, 4-12, 16-29, 43-47, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) is essentially a mobile phone. 59. Mobile system according to claims 1, 2, 4-12, 16-29, 43-58, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) is essentially a programmable device. 60. A method for displaying, processing and storing recorded electrophysiological signals in remote centers in real time comprises: (a) Providing a mobile system according to claims 1, 2, 4-12, 16-29, 43-59. (b) Providing at least one device controller for storing, processing and displaying recorded electrophysiological signals located at remote centers (27). (c) Providing at least one controller that operates the device for controlling the device for recording and sending electrophysiological signals (28). (d) Entering the identifier of the patient or subject to be recorded (312) into the device for controlling the device for recording and sending electrophysiological signals (28). (e) Inputting recording metadata, such as, but not limited to, the patient's first and last name, age, sex, time of recording (313) to the device for controlling the device for recording and sending electrophysiological signals (28). (f) Entering the controller selection into the electrophysiological signal recording and sending device control device (23) to send the recorded electrophysiological signals to the central server (314). (g) Sending metadata and selecting the controller to send the recorded electrophysiological signals to the central server (24) to the device for recording and sending electrophysiological signals (23) by the control device for the device for recording and sending electrophysiological signals (28). (h) Activating the module to communicate (611) with the central server (24) over a remote data transmission network, such as, but not limited to, the Internet. (i) Sending the identifier of the device used to record and send the electrophysiological signals and metadata (612) to the central server (24) by the device for recording and transmitting the electrophysiological signals (23). (j) Entering the identifier of the device used for recording and sending electrophysiological signals (23) in the table of active devices for recording and sending electrophysiological signals on the central server (613). (k) Entering the identifier of the device for recording and sending electrophysiological signals to the device for storing, processing and displaying recorded electrophysiological signals (27) by the controller of the device for storing, processing and displaying recorded electrophysiological signals located in remote centers. (1) Sending the identifier of the recording device and sending the electrophysiological signals (614) to the central server (24) of the remote device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27). (m) Checking the identifier of the recording and sending electrophysiological signal device in the table of active recording and sending electrophysiological signal devices (615) by the central server (24). (n) Sending a signal to stop recording to a device for storing, processing and displaying electrophysiological signals in remote centers (27) in case the identifier of the device for recording and sending electrophysiological signals is not contained in the table of active devices (620) in the central server (24). (o) Start of continuous sending of recorded electrophysiological signals (616) in the device for storing, processing and displaying electrophysiological signals located in remote centers (27) by the central server (24) in case the identifier of the device for recording and sending electrophysiological signals is contained in the table of active devices on the central server. (p) Storing the meta data and the recorded electrophysiological signals (617) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located at the remote centers (27). (q) Displaying the electrophysiological signals on the screen (617) of the device for storing, processing and displaying the recorded electrophysiological signals located at the remote centers (27) when the controller has chosen to display the electrophysiological signals. (r) Using a software application for processing the recorded electrophysiological signals (617) on the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller (s) Storing the meta data and the processed electrophysiological signals (617) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (t) Displaying the processed electrophysiological signals on the screen (617) of the device for storing, processing and displaying the recorded electrophysiological signals located in the remote centers (27) by the controller. (u) Display, processing and storage of electrophysiological signals (617) in the device for storing, displaying and processing electrophysiological signals in remote centers (27) can be carried out cyclically, continuously and an indefinite number of times. (v) Input of a signal to stop the recording of electrophysiological signals in the device for controlling the recording device and sending of electrophysiological signals by the controller. (w) Sending a signal to stop recording electrophysiological signals [618] to the device for recording and sending electrophysiological signals (23) by the device for controlling the device for recording and sending electrophysiological signals (28). (x) Sending a signal to stop recording electrophysiological signals to the central server (24) by the device for recording and sending electrophysiological signals (23). (y) Deleting the recording and sending electrophysiological device identifier from the table of active recording and sending electrophysiological devices (619) by the central server. (z) Sending a signal to stop recording electrophysiological signals to a device for storing, processing and displaying electrophysiological signals located in remote centers (27) by the central server (24). (aa) Termination of recording of electrophysiological signals (620) in the device for recording and sending of electrophysiological signals. 61. Mobile system according to claims 1, 2, 4-12 and 60, characterized in that the device identifier for recording and sending electrophysiological signals is unique and contained in each device for recording and sending electrophysiological signals. 62. Mobile system according to claims 1, 2, 4-12, 16-29, 43 and 60, characterized in that the meta data includes an identifier of the subject or patient being recorded. 63. Mobile system according to claims 1, 2, 4-12, 16-29, 43 and 60, characterized in that the meta data includes a list of data that the controller of the device for controlling the device for recording and sending electrophysiological signals has determined to be necessary for the identification and further analysis of the recorded signals. 64. Mobile system according to claims 1, 2, 4-12, 16-29, 43-60, characterized in that the device for storing, processing and displaying recorded electrophysiological signals in remote centers (27) essentially contains a software application for processing electrophysiological signals. 65. A mobile system according to claims 1, 2, 4-12, 16-29, 43-60, characterized in that the method for storing recorded electrophysiological data in a central database and the method for displaying, processing and storing recorded electrophysiological signals in remote centers in real time can take place in parallel, independently and asynchronously using the same central server (24). 66. A method for displaying, processing and storing recorded electrophysiological signals near a device for recording and sending electrophysiological signals in real time comprises: (a) Providing the system of claims 1, 3, 5, 6, 7-12, 16-42. (b] Providing at least one device controller for storing, processing and displaying recorded electrophysiological signals located near a device for recording and sending electrophysiological signals (26). (c] Providing at least one controller that controls the device for controlling the recording and sending electrophysiological signals (28). (d] Inputting recording metadata to the device controlling the recording and sending electrophysiological signals, such as, but not limited to, the identifier of the patient or subject being recorded (312], the patient's first and last name, age, gender, recording time (313). (e) Inputting the selection of the controller to the controlling device for recording and sending electrophysiological signals to send the data to the device for storing, processing and displaying signals that located near the device for recording and sending electrophysiological signals (314). (f] Sending the meta data, the identifier of the device used for recording and sending electrophysiological signals and the selection of the controller to send electrophysiological signals to the device for storing, processing and displaying the signal located near the device for recording and sending electrophysiological signals (26) to the device for recording and transmitting electrophysiological signals (23) by the device for controlling the device for recording and transmitting electrophysiological signals (28). short-range communication (711) on the electrophysiological signal recording and sending device (23) and connecting the signal storage, processing and display device located in the vicinity of the electrophysiological signal recording and sending device (26) to the electrophysiological signal recording and sending device (23) via a wireless digital data transmission network, such as, but not limited to, Bluetooth or WiFi networks of electrophysiological signals located near the device for recording and sending electrophysiological signals (26) by a device for recording and sending electrophysiological signals (23). (i) Storing the meta data and the recorded electrophysiological signals (713) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located near the device for sending and recording the electrophysiological signals (26). (j) Display of electrophysiological signals (713) on the screen of a device for storing, processing and displaying recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26). (k) Using a software application for processing the recorded electrophysiological signals (713) on a device for storing, processing and displaying the recorded electrophysiological signals located near the device for recording and sending the electrophysiological signals (26) by the controller. (1) Storage of meta data and processed electrophysiological signals (713) in the memory of the device for storing, processing and displaying the recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26). (m) Display of Processed of electrophysiological signals (713) on the screen of the device for storing, processing and displaying recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26). (n) Inputting a signal to stop the recording of electrophysiological signals in the device for controlling the recording device and sending the electrophysiological signals (28) by the controller. (o) Sending a signal to stop recording electrophysiological signals to the device for recording and sending electrophysiological signals (23) by the device for controlling the device for recording and sending electrophysiological signals (28). (p) Sending a signal to stop recording electrophysiological signals to a signal storage, processing and display device located near the device for recording and sending electrophysiological signals (26) by the device for recording and sending electrophysiological signals (23). (q) Termination of recording of electrophysiological signals (714) in the device for recording and sending electrophysiological signals (23). 67. The mobile system according to claims 1, 2, 5, 6, 30-42 and 66, characterized in that the device for storing, processing and displaying recorded electrophysiological signals located near the device for recording and sending electrophysiological signals (26) contains software applications for processing electrophysiological signals.