RO71183B - Process for preparing substituited 20-on-steroids - Google Patents
Process for preparing substituited 20-on-steroidsInfo
- Publication number
- RO71183B RO71183B RO72410A RO7241072A RO71183B RO 71183 B RO71183 B RO 71183B RO 72410 A RO72410 A RO 72410A RO 7241072 A RO7241072 A RO 7241072A RO 71183 B RO71183 B RO 71183B
- Authority
- RO
- Romania
- Prior art keywords
- steroids
- substituited
- preparing
- hydrogen
- chlorine
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000001257 hydrogen Chemical group 0.000 abstract 3
- 229910052739 hydrogen Chemical group 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedeu de preparare a 20-on-steroidelor substituite, cu formula generala I din pag.1 a descrierii, în care X reprezinta clor sau hidrogen, Z reprezinta o grupa hidroxil sau clor, Y este hidrogen, fluor sau clor, R reprezinta un atom de hidrogen sau un rest de hidrocarbura eventual substituite.A process for the preparation of the substituted 20-on steroids of general formula I of the disclosure in which X represents chlorine or hydrogen, Z represents a hydroxyl or chlorine group, Y is hydrogen, fluorine or chlorine, R represents an atom hydrogen or an optionally substituted hydrocarbon moiety.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712150268 DE2150268C3 (en) | 1971-10-04 | 1971-10-04 | Pregnanic acid derivatives, processes for their preparation and pharmaceuticals containing them |
| DE2204361A DE2204361A1 (en) | 1972-01-27 | 1972-01-27 | 3, 20-dioxo-pregnene and pregnadiene 21-acids - antiinflammatories for topical application |
| DE2204360A DE2204360C2 (en) | 1972-01-27 | 1972-01-27 | New pregnanic acid derivatives, processes for their production and pharmaceutical preparations containing them |
| DE2204358A DE2204358C2 (en) | 1972-01-27 | 1972-01-27 | Process for the preparation of pregnanic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO71183B true RO71183B (en) | 1983-07-30 |
| RO71183A RO71183A (en) | 1983-08-03 |
Family
ID=27431338
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7272410A RO71183A (en) | 1971-10-04 | 1972-10-03 | PROCESS FOR PREPARATION OF SUBSTITUTED 20-ON-STEROIDS |
| RO7284617A RO70725A (en) | 1971-10-04 | 1972-10-03 | PROCESS FOR OBTAINING PREGNANIC ACID DERIVATIVES |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7284617A RO70725A (en) | 1971-10-04 | 1972-10-03 | PROCESS FOR OBTAINING PREGNANIC ACID DERIVATIVES |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5837320B2 (en) |
| BE (1) | BE779869A (en) |
| CA (1) | CA978518A (en) |
| CH (2) | CH588509A5 (en) |
| DD (1) | DD95565B1 (en) |
| DK (1) | DK136612C (en) |
| EG (1) | EG10635A (en) |
| FI (1) | FI51103C (en) |
| FR (1) | FR2156518B1 (en) |
| GB (1) | GB1387911A (en) |
| HU (1) | HU165261B (en) |
| IE (1) | IE36120B1 (en) |
| IL (1) | IL39735A (en) |
| LU (1) | LU66213A1 (en) |
| NL (1) | NL179059C (en) |
| NO (1) | NO138808C (en) |
| RO (2) | RO71183A (en) |
| YU (1) | YU35148B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE38659B1 (en) * | 1972-12-22 | 1978-05-10 | Schering Ag | New pregnane acid derivatives |
| DE2444618C2 (en) * | 1974-09-16 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | New Pregnan-21-Acid-Derivatives |
| DE2365102C2 (en) * | 1973-12-21 | 1982-12-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | New pregnanic acid derivatives |
| DE2332663C2 (en) * | 1973-06-23 | 1986-07-31 | Schering AG, 1000 Berlin und 4709 Bergkamen | Use of corticosteroid active ingredients for inhalation therapy |
| DE2336438C2 (en) * | 1973-07-14 | 1983-07-07 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Process for making 17β-oxalyl steroids |
| DE2862012D1 (en) * | 1978-06-12 | 1982-10-28 | Schering Ag | New corticoids, processes for their preparation and pharmaceutical compositions containing them |
| SE8506015D0 (en) * | 1985-12-19 | 1985-12-19 | Draco Ab | NOVEL 16,17-ACETALSUBSTITUTED PREGNANE 21-OIC ACID DERIVATIVES |
| US5215979A (en) * | 1985-12-19 | 1993-06-01 | Aktiebolaget Draco | 16,17-acetalsubstituted pregnane 21-oic acid derivatives |
| JP2007237153A (en) * | 2006-03-06 | 2007-09-20 | Npo Machinami Ikuseikai | Air mixing and agitation technology |
-
1972
- 1972-02-23 GB GB829972A patent/GB1387911A/en not_active Expired
- 1972-02-23 DD DD72161068A patent/DD95565B1/en unknown
- 1972-02-23 YU YU443/72A patent/YU35148B/en unknown
- 1972-02-24 CH CH395876A patent/CH588509A5/xx not_active IP Right Cessation
- 1972-02-24 CH CH264772A patent/CH589671A5/xx not_active IP Right Cessation
- 1972-02-24 IE IE227/72A patent/IE36120B1/en unknown
- 1972-02-24 EG EG69/72A patent/EG10635A/en active
- 1972-02-24 DK DK86472A patent/DK136612C/en not_active IP Right Cessation
- 1972-02-25 BE BE779869A patent/BE779869A/en not_active IP Right Cessation
- 1972-02-25 NO NO581/72A patent/NO138808C/en unknown
- 1972-02-25 FR FR7206522A patent/FR2156518B1/fr not_active Expired
- 1972-02-25 FI FI720497A patent/FI51103C/en active
- 1972-06-21 HU HUSCHE398*1A patent/HU165261B/hu not_active IP Right Cessation
- 1972-06-21 IL IL39735A patent/IL39735A/en unknown
- 1972-10-02 LU LU66213A patent/LU66213A1/xx unknown
- 1972-10-03 RO RO7272410A patent/RO71183A/en unknown
- 1972-10-03 RO RO7284617A patent/RO70725A/en unknown
- 1972-10-04 CA CA153,227A patent/CA978518A/en not_active Expired
- 1972-10-04 NL NLAANVRAGE7213456,A patent/NL179059C/en not_active IP Right Cessation
- 1972-10-04 JP JP47100273A patent/JPS5837320B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5837320B2 (en) | 1983-08-15 |
| FR2156518B1 (en) | 1975-06-13 |
| FI51103C (en) | 1976-10-11 |
| IL39735A (en) | 1975-08-31 |
| BE779869A (en) | 1972-08-25 |
| LU66213A1 (en) | 1973-01-23 |
| CA978518A (en) | 1975-11-25 |
| FR2156518A1 (en) | 1973-06-01 |
| IE36120B1 (en) | 1976-08-18 |
| EG10635A (en) | 1976-09-30 |
| GB1387911A (en) | 1975-03-19 |
| YU44372A (en) | 1980-03-15 |
| NL179059C (en) | 1986-07-01 |
| NO138808C (en) | 1978-11-15 |
| NL179059B (en) | 1986-02-03 |
| DK136612C (en) | 1978-04-10 |
| CH588509A5 (en) | 1977-06-15 |
| DK136612B (en) | 1977-10-31 |
| FI51103B (en) | 1976-06-30 |
| DD95565A5 (en) | 1973-02-12 |
| NO138808B (en) | 1978-08-07 |
| DD95565B1 (en) | 1986-10-29 |
| RO70725A (en) | 1982-09-09 |
| NL7213456A (en) | 1973-04-06 |
| HU165261B (en) | 1974-07-27 |
| IE36120L (en) | 1973-04-04 |
| IL39735A0 (en) | 1972-12-29 |
| JPS4861464A (en) | 1973-08-28 |
| YU35148B (en) | 1980-09-25 |
| CH589671A5 (en) | 1977-07-15 |
| RO71183A (en) | 1983-08-03 |
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