PT920426E - Novos derivados de tiazole com efeito inibidor de fosfodiesterase - Google Patents

Novos derivados de tiazole com efeito inibidor de fosfodiesterase

Info

Publication number: PT920426E
Authority: PT; Portugal
Prior art keywords: new; phosphodiesterase inhibitor; pct; inhibitor effect; tiazole
Prior art date: 1996-08-26

Application number

PT97940080T

Other languages

English (en)

Inventor

Rolf Beume

Dietrich Hafner

Hans-Peter Kley

Thomas Bar

Thomas Martin

Hildegard Boss

Dieter Flockerzi

Beate Schmidt

Armin Hatzelmann

Hermann Amschler

Ulrich Thibaut

Wolf-Rudiger Ulrich

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-26

Filing date

1997-08-13

Publication date

2004-02-27

1997-08-13 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2004-02-27 Publication of PT920426E publication Critical patent/PT920426E/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

PT97940080T 1996-08-26 1997-08-13 Novos derivados de tiazole com efeito inibidor de fosfodiesterase PT920426E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19634411		1996-08-26
EP96113737		1996-08-28

Publications (1)

Publication Number	Publication Date
PT920426E true PT920426E (pt)	2004-02-27

Family

ID=26028746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97940080T PT920426E (pt)	1996-08-26	1997-08-13	Novos derivados de tiazole com efeito inibidor de fosfodiesterase

Country Status (12)

Country	Link
US (1)	US6011037A (pt)
EP (1)	EP0920426B9 (pt)
JP (1)	JP2000516940A (pt)
AT (1)	ATE251153T1 (pt)
AU (1)	AU4205197A (pt)
CY (1)	CY2509B1 (pt)
DE (1)	DE59710816D1 (pt)
DK (1)	DK0920426T3 (pt)
ES (1)	ES2208950T3 (pt)
PT (1)	PT920426E (pt)
SI (1)	SI0920426T1 (pt)
WO (1)	WO1998008841A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK287231B6 (sk)	1999-08-21	2010-04-07	Nycomed Gmbh	Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
CA2451981C (en)	2001-08-13	2012-02-21	Janssen Pharmaceutica N.V.	2,4,5-trisubstituted thiazolyl derivatives and their antiinflammatory activity
AU2004226353A1 (en)	2003-04-01	2004-10-14	Laboratoires Serono Sa	Inhibitors of phosphodiesterases in infertility
EP2275096A3 (en)	2005-08-26	2011-07-13	Braincells, Inc.	Neurogenesis via modulation of the muscarinic receptors
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
JP2009513672A (ja)	2005-10-31	2009-04-02	ブレインセルス，インコーポレイティド	神経発生のｇａｂａ受容体媒介調節
WO2007104035A1 (en) *	2006-03-08	2007-09-13	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US20100216734A1 (en) *	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2382975A3 (en)	2006-05-09	2012-02-29	Braincells, Inc.	Neurogenesis by modulating angiotensin
CA2651862A1 (en) *	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
KR20090064418A (ko) *	2006-09-08	2009-06-18	브레인셀즈 인코퍼레이션	4-아실아미노피리딘 유도체 포함 조합물
WO2008036678A2 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
WO2012154518A1 (en)	2011-05-10	2012-11-15	Merck Sharp & Dohme Corp.	Bipyridylaminopyridines as syk inhibitors
WO2012154520A1 (en)	2011-05-10	2012-11-15	Merck Sharp & Dohme Corp.	Pyridyl aminopyridines as syk inhibitors
KR20140028062A (ko) *	2011-05-10	2014-03-07	머크 샤프 앤드 돔 코포레이션	Syk 억제제로서의 아미노피리미딘
US20150119399A1 (en)	2012-01-10	2015-04-30	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2245660T3 (es) *	1990-11-30	2006-01-16	Otsuka Pharmaceutical Co., Ltd.	Derivados de azol y su utilizacion como inhibidores de los radicales superoxidos.
WO1993024472A1 (fr) *	1992-05-29	1993-12-09	Otsuka Pharmaceutical Co., Ltd.	Derive de thiazole
GB9315017D0 (en) *	1993-07-20	1993-09-01	Glaxo Lab Sa	Chemical compounds
JPH10504542A (ja) *	1994-07-27	1998-05-06	ジー．ディー．サールアンドカンパニー	炎症処置用の置換チアゾール化合物

1997
- 1997-08-13 AU AU42051/97A patent/AU4205197A/en not_active Abandoned
- 1997-08-13 PT PT97940080T patent/PT920426E/pt unknown
- 1997-08-13 WO PCT/EP1997/004435 patent/WO1998008841A1/de not_active Ceased
- 1997-08-13 ES ES97940080T patent/ES2208950T3/es not_active Expired - Lifetime
- 1997-08-13 DK DK97940080T patent/DK0920426T3/da active
- 1997-08-13 JP JP10511228A patent/JP2000516940A/ja active Pending
- 1997-08-13 SI SI9730611T patent/SI0920426T1/xx unknown
- 1997-08-13 DE DE59710816T patent/DE59710816D1/de not_active Expired - Fee Related
- 1997-08-13 US US09/147,740 patent/US6011037A/en not_active Expired - Fee Related
- 1997-08-13 AT AT97940080T patent/ATE251153T1/de not_active IP Right Cessation
- 1997-08-13 EP EP97940080A patent/EP0920426B9/de not_active Expired - Lifetime
2005
- 2005-03-23 CY CY0500019A patent/CY2509B1/xx unknown

Also Published As

Publication number	Publication date
SI0920426T1 (en)	2004-04-30
EP0920426A1 (de)	1999-06-09
CY2509B1 (en)	2005-12-23
DE59710816D1 (de)	2003-11-06
ATE251153T1 (de)	2003-10-15
AU4205197A (en)	1998-03-19
ES2208950T3 (es)	2004-06-16
US6011037A (en)	2000-01-04
DK0920426T3 (da)	2004-02-02
WO1998008841A1 (de)	1998-03-05
EP0920426B9 (de)	2005-04-06
JP2000516940A (ja)	2000-12-19
EP0920426B1 (de)	2003-10-01

Publication	Publication Date	Title
PT920426E (pt)	2004-02-27	Novos derivados de tiazole com efeito inibidor de fosfodiesterase
ATE233247T1 (de)	2003-03-15	Phtalazinonen
DK1070056T3 (da)	2004-11-08	Phthalazinon-PDE III/IV-inhibitorer
DK0937074T3 (da)	2003-06-23	Benzonaphthyridiner som bronkiale terapeutiske midler
MX9700557A (es)	1997-12-31	Dihidrobenzofuranos.
DK1000035T3 (da)	2003-03-17	Substituerede 6-phenylphenanthridiner
ATE233252T1 (de)	2003-03-15	Substituierte dihydrobenzofurane als pde- hemmstoffe
IL122737A (en)	2003-01-12	Salts of amidine derivatives and cyclooxygenase inhibitors, their preparation and pharmaceutical compositions containing them
PT1003724E (pt)	2003-06-30	Derivados substituidos com accao antiviral
GB2324091B (en)	2000-11-15	Metalloproteinase inhibitors
SI0937075T1 (en)	2004-06-30	New Imidazo- and Oxazolopyridines as Phosphodiesterase Inhibitors.