PT916656E - Metodo para producao de derivados de pirrolidinona - Google Patents
Metodo para producao de derivados de pirrolidinonaInfo
- Publication number
- PT916656E PT916656E PT98121178T PT98121178T PT916656E PT 916656 E PT916656 E PT 916656E PT 98121178 T PT98121178 T PT 98121178T PT 98121178 T PT98121178 T PT 98121178T PT 916656 E PT916656 E PT 916656E
- Authority
- PT
- Portugal
- Prior art keywords
- group
- carbon atoms
- useful
- formula
- compound
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 150000004040 pyrrolidinones Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- FDKLLWKMYAMLIF-UHFFFAOYSA-N cyclopropane-1,1-dicarboxylic acid Chemical compound OC(=O)C1(C(O)=O)CC1 FDKLLWKMYAMLIF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000005010 perfluoroalkyl group Chemical group 0.000 abstract 1
- -1 pyrrolidinone compound Chemical class 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31378497A JP4286921B2 (ja) | 1997-11-14 | 1997-11-14 | ３−カルボキシ−１−フェニル−２−ピロリジノン誘導体および製造法 |
| JP31999497A JPH11152267A (ja) | 1997-11-20 | 1997-11-20 | ピロリジノン誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT916656E true PT916656E (pt) | 2004-02-27 |
Family
ID=26567707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98121178T PT916656E (pt) | 1997-11-14 | 1998-11-13 | Metodo para producao de derivados de pirrolidinona |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6207825B1 (pt) |
| EP (1) | EP0916656B1 (pt) |
| AT (1) | ATE249434T1 (pt) |
| DE (1) | DE69817974T2 (pt) |
| DK (1) | DK0916656T3 (pt) |
| ES (1) | ES2205362T3 (pt) |
| PT (1) | PT916656E (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1950211A4 (en) * | 2005-11-18 | 2011-08-31 | Eisai R&D Man Co Ltd | PROCESS FOR PREPARING A CINEMA ACID AMID DERIVATIVE |
| JP5600183B2 (ja) | 2010-01-22 | 2014-10-01 | ノバルティス アーゲー | 中性エンドペプチダーゼ阻害剤の中間体およびその調製方法 |
| WO2012025501A1 (en) | 2010-08-23 | 2012-03-01 | Novartis Ag | Process for the preparation of intermediates for the manufacture of nep inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5175157A (en) * | 1985-11-27 | 1992-12-29 | Boehringer Ingelheim Gmbh | Cyclic amine derivatives, pharmaceutical compositions containing these compounds and methods for preparing them |
| DE69025418T2 (de) * | 1989-04-19 | 1996-11-14 | Otsuka Pharma Co Ltd | Phenylcarbonsäurederivate mit einem Heterocyclus |
| JPH02300119A (ja) * | 1989-05-11 | 1990-12-12 | Kanegafuchi Chem Ind Co Ltd | 過酸化脂質生成抑制剤 |
| US5538985A (en) * | 1994-01-27 | 1996-07-23 | Mitsui Toatsu Chemicals, Inc. | Pyrrolidinone derivatives |
| JP3786983B2 (ja) * | 1994-01-27 | 2006-06-21 | シエーリング アクチエンゲゼルシャフト | ピロリジノン誘導体 |
| GB9411008D0 (en) * | 1994-06-02 | 1994-07-20 | Zeneca Ltd | Herbicides |
| GB9510744D0 (en) * | 1995-05-26 | 1995-07-19 | Zeneca Ltd | Chemical process |
| JP4260911B2 (ja) * | 1997-12-15 | 2009-04-30 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | ピロリジノン誘導体のラセミ化方法 |
| JP2000143624A (ja) * | 1998-11-13 | 2000-05-26 | Mitsui Chemicals Inc | ３−カルボキシ−１−フェニル−２−ピロリジノン誘導体および製造法 |
-
1998
- 1998-11-13 EP EP98121178A patent/EP0916656B1/en not_active Expired - Lifetime
- 1998-11-13 PT PT98121178T patent/PT916656E/pt unknown
- 1998-11-13 ES ES98121178T patent/ES2205362T3/es not_active Expired - Lifetime
- 1998-11-13 US US09/190,297 patent/US6207825B1/en not_active Expired - Fee Related
- 1998-11-13 DE DE69817974T patent/DE69817974T2/de not_active Expired - Fee Related
- 1998-11-13 AT AT98121178T patent/ATE249434T1/de not_active IP Right Cessation
- 1998-11-13 DK DK98121178T patent/DK0916656T3/da active
-
2000
- 2000-10-24 US US09/694,340 patent/US6555694B1/en not_active Expired - Fee Related
-
2003
- 2003-02-21 US US10/369,808 patent/US20030171578A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6555694B1 (en) | 2003-04-29 |
| DK0916656T3 (da) | 2004-01-05 |
| US20030171578A1 (en) | 2003-09-11 |
| EP0916656A2 (en) | 1999-05-19 |
| EP0916656A3 (en) | 2001-04-11 |
| ES2205362T3 (es) | 2004-05-01 |
| EP0916656B1 (en) | 2003-09-10 |
| DE69817974D1 (de) | 2003-10-16 |
| DE69817974T2 (de) | 2004-07-22 |
| ATE249434T1 (de) | 2003-09-15 |
| US6207825B1 (en) | 2001-03-27 |
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