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PT87545A - Prostaglandin-lipid formulations - Google Patents

Prostaglandin-lipid formulations

Info

Publication number
PT87545A
PT87545A PT87545A PT8754588A PT87545A PT 87545 A PT87545 A PT 87545A PT 87545 A PT87545 A PT 87545A PT 8754588 A PT8754588 A PT 8754588A PT 87545 A PT87545 A PT 87545A
Authority
PT
Portugal
Prior art keywords
prostaglandin
transmembrane
liposomes
lipid formulations
gradient
Prior art date
Application number
PT87545A
Other languages
English (en)
Other versions
PT87545B (pt
Inventor
Robert P Lenk
Robert L Suddith
Michelle M Tomsho
Robert J Klimchak
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of PT87545A publication Critical patent/PT87545A/pt
Publication of PT87545B publication Critical patent/PT87545B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT87545A 1987-05-22 1988-05-20 Processo para a preparacao de composicoes lipossomicas compreendendo metabolito de acido araquidonico PT87545B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5330587A 1987-05-22 1987-05-22

Publications (2)

Publication Number Publication Date
PT87545A true PT87545A (pt) 1989-05-31
PT87545B PT87545B (pt) 1992-12-31

Family

ID=21983292

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87545A PT87545B (pt) 1987-05-22 1988-05-20 Processo para a preparacao de composicoes lipossomicas compreendendo metabolito de acido araquidonico

Country Status (13)

Country Link
US (1) US5082664A (pt)
EP (1) EP0292403B1 (pt)
KR (1) KR970005171B1 (pt)
AT (1) ATE109982T1 (pt)
AU (1) AU617678B2 (pt)
CA (1) CA1323838C (pt)
DE (1) DE3851090T2 (pt)
ES (1) ES2058317T3 (pt)
FI (1) FI95199C (pt)
HK (1) HK1007496A1 (pt)
PT (1) PT87545B (pt)
WO (1) WO1988009170A1 (pt)
ZA (1) ZA883653B (pt)

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MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5811118A (en) * 1987-05-22 1998-09-22 The Liposome Company, Inc. Methods of treatment using unilamellar liposomal arachidonic acid metabolite formulations
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
DE69025787T2 (de) * 1989-04-04 1996-10-31 Beiersdorf Ag Mittel zur Atopieprophylaxe
US5591446A (en) * 1989-04-04 1997-01-07 Beiersdorf, A.G. Methods and agents for the prophylaxis of atopy
DE3910761A1 (de) * 1989-04-04 1990-10-11 Bodo Dr Med Melnik Mittel zur atopie-prophylaxe
JPH0395118A (ja) * 1989-09-07 1991-04-19 Green Cross Corp:The プロスタグランジン含有脂肪小体製剤
US5882678A (en) * 1990-01-12 1999-03-16 The Liposome Co, Inc. Interdigitation-fusion liposomes containing arachidonic acid metabolites
EP0512916B1 (en) * 1991-05-07 1999-02-03 The Liposome Company, Inc. Liposomal prostaglandin formulations
DE4125255A1 (de) * 1991-07-31 1993-02-04 Knoll Ag Prostaglandin e (pfeil abwaerts)1(pfeil abwaerts)-formulierung
JP3168550B2 (ja) * 1992-12-02 2001-05-21 株式会社林原生物化学研究所 脱水剤およびそれを用いる含水物の脱水方法並びにその方法で得られる脱水物品
US6005100A (en) * 1992-12-02 1999-12-21 Kabushiki Kaisha Hayashibara Seitbutsu Kagaku Kenkyujo Trehalose composition for prolonging product shelf life
CA2159596C (en) * 1993-04-02 2002-06-11 Royden Coe Method of producing liposomes
ES2154680T3 (es) 1993-07-08 2001-04-16 Liposome Co Inc Metodo para controlar el tamaño de los liposomas.
US5853755A (en) * 1993-07-28 1998-12-29 Pharmaderm Laboratories Ltd. Biphasic multilamellar lipid vesicles
ATE187071T1 (de) * 1993-10-27 1999-12-15 Upjohn Co Stabilisiertes prostaglandin e1
KR100355246B1 (ko) * 1993-11-04 2003-01-06 더 리포좀 컴퍼니, 인코퍼레이티드 단층라멜라리포좀성아라키돈산대사물질조성물을사용한치료방법
KR960705546A (ko) * 1993-11-16 1996-11-08 카롤 질레스피 아라키돈산 대사물질을 포함하는 인터디지테이션-퓨젼 리포좀(interdigitation-fusion liposomes containing arachidonic acid metabolites)
US5840328A (en) * 1994-01-11 1998-11-24 The Liposome Company, Inc. Treatment using arachidonic acid metabolite and particulate formulations
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
JPH10508578A (ja) * 1994-09-23 1998-08-25 ザ リポソーム カンパニー、インコーポレーテッド 凍結乾燥リポソーム生成物の製造方法
US5718917A (en) * 1995-12-15 1998-02-17 Harvard Scientific Corporation PGE-1 containing lyophilized liposomes for use in the treatment of erectile dysfunction
US6447800B2 (en) * 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
US5980551A (en) * 1997-02-07 1999-11-09 Endovasc Ltd., Inc. Composition and method for making a biodegradable drug delivery stent
US6001333A (en) * 1997-09-12 1999-12-14 See; Jackie R. Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging
US6019999A (en) * 1997-12-03 2000-02-01 Miller; David F. Process for making liposomal ion-exchange whey protein and products thereof
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
WO2008029763A1 (en) * 2006-09-05 2008-03-13 Q.P. Corporation Prostaglandin fat emulsion, method for producing the same, method for stabilizing the same, and emulsifying agent
US20090035725A1 (en) * 2007-08-02 2009-02-05 Ondine International, Ltd. Photodisinfection of oral cavity
EP2331070A1 (en) * 2008-09-26 2011-06-15 Phares Pharmaceutical Research N.V. Method of solubilising biologically active compounds
US9835618B1 (en) * 2009-02-06 2017-12-05 Los Alamos National Security, Llc Discovery, detection and use of biomarkers
IT1397867B1 (it) * 2010-02-03 2013-02-04 Brotzu Liposomi contenenti prostaglandina e1 (pge1), formulazioni che li contengono e loro uso
WO2012021107A2 (en) * 2010-08-12 2012-02-16 Nanyang Technological University A liposomal formulation for ocular drug delivery
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
US9962393B1 (en) * 2015-06-21 2018-05-08 Angiosoma Research, Inc. Method for treating vascular disease by administering a liposomal prostaglandin composition
BR112020020127A2 (pt) * 2018-05-07 2021-01-05 Pharmosa Biopharm Inc. Composição farmacêutica, método de tratamento de uma doença respiratória e método para reduzir o efeito colateral de um treprostinil inalado na via respiratória superior
WO2022212863A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Liposome formulations for pesticide delivery and methods for producing and using the same

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* Cited by examiner, † Cited by third party
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FR2274122A1 (fr) * 1974-06-07 1976-01-02 Cgr Mev Procede de centrage d'un faisceau de balayage a rayonnement ionisant et dispositif permettant la mise en oeuvre de ce procede
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
US4086257A (en) * 1976-10-12 1978-04-25 Sears Barry D Phosphatidyl quaternary ammonium compounds
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
CH621479A5 (pt) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
JPS55153713A (en) * 1979-05-02 1980-11-29 Kureha Chem Ind Co Ltd Pharmaceutical preparation of ribosome containing active substance
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンｅ↓１脂肪乳剤
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
WO1985000968A1 (en) * 1983-09-06 1985-03-14 Health Research, Inc. Liposome delivery method for decreasing the toxicity of an antitumor drug
JPH0818989B2 (ja) * 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
US4721612A (en) * 1984-04-12 1988-01-26 The Liposome Company, Inc. Steroidal liposomes
CA1264668A (en) * 1984-06-20 1990-01-23 Pieter R. Cullis Extrusion techniques for producing liposomes
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
JPS61100518A (ja) * 1984-10-22 1986-05-19 Ono Pharmaceut Co Ltd ジミリストイルホスフアチジルコリンを主成分とする凍結乾燥されたリポゾ−ム製剤
EP0231261B1 (en) * 1985-07-05 1994-04-06 The Liposome Company, Inc. Multilamellar liposomes having improved trapping efficiencies

Also Published As

Publication number Publication date
FI895554A0 (fi) 1989-11-21
AU617678B2 (en) 1991-12-05
US5082664A (en) 1992-01-21
FI95199B (fi) 1995-09-29
DE3851090T2 (de) 1995-01-12
KR890701093A (ko) 1989-12-19
ES2058317T3 (es) 1994-11-01
PT87545B (pt) 1992-12-31
AU1954588A (en) 1988-12-21
HK1007496A1 (en) 1999-04-16
EP0292403A2 (en) 1988-11-23
DE3851090D1 (de) 1994-09-22
KR970005171B1 (ko) 1997-04-14
EP0292403A3 (en) 1988-12-21
CA1323838C (en) 1993-11-02
ATE109982T1 (de) 1994-09-15
FI95199C (fi) 1996-01-10
EP0292403B1 (en) 1994-08-17
ZA883653B (en) 1989-03-29
WO1988009170A1 (en) 1988-12-01

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920727