PT83495A - Process for the preparation of n-substituted diphenylpiperidines and of pharmaceutical compositions containing the same - Google Patents
Process for the preparation of n-substituted diphenylpiperidines and of pharmaceutical compositions containing the sameInfo
- Publication number
- PT83495A PT83495A PT83495A PT8349586A PT83495A PT 83495 A PT83495 A PT 83495A PT 83495 A PT83495 A PT 83495A PT 8349586 A PT8349586 A PT 8349586A PT 83495 A PT83495 A PT 83495A
- Authority
- PT
- Portugal
- Prior art keywords
- diphenylpiperidines
- substituted
- preparation
- same
- pharmaceutical compositions
- Prior art date
Links
- BTVVEKSXUOEVAY-UHFFFAOYSA-N 4,4-diphenylpiperidine Chemical class C1CNCCC1(C=1C=CC=CC=1)C1=CC=CC=C1 BTVVEKSXUOEVAY-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/785,113 US4632925A (en) | 1985-10-07 | 1985-10-07 | N-substituted diphenylpiperidines and antiobesity use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT83495A true PT83495A (en) | 1986-11-01 |
| PT83495B PT83495B (en) | 1989-05-31 |
Family
ID=25134481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT83495A PT83495B (en) | 1985-10-07 | 1986-10-06 | METHOD FOR THE PREPARATION OF N-SUBSTITUTED DIPHENYLPIPERIDINS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4632925A (en) |
| EP (1) | EP0221376B1 (en) |
| JP (1) | JPH0633254B2 (en) |
| KR (1) | KR870003984A (en) |
| AR (1) | AR241422A1 (en) |
| AT (1) | ATE53997T1 (en) |
| AU (1) | AU593844B2 (en) |
| CA (1) | CA1281326C (en) |
| DE (1) | DE3672134D1 (en) |
| DK (1) | DK168291B1 (en) |
| ES (1) | ES2005074A6 (en) |
| FI (1) | FI85020C (en) |
| GR (1) | GR862513B (en) |
| HU (1) | HU196200B (en) |
| IE (1) | IE59434B1 (en) |
| IL (1) | IL80232A0 (en) |
| MC (1) | MC1769A1 (en) |
| NO (1) | NO166127C (en) |
| NZ (1) | NZ217798A (en) |
| PH (1) | PH24167A (en) |
| PT (1) | PT83495B (en) |
| SG (1) | SG17593G (en) |
| ZA (1) | ZA867375B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78939A (en) * | 1986-01-17 | 1990-04-29 | Robins Co Inc A H | Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds |
| GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
| AU646519B2 (en) * | 1990-10-10 | 1994-02-24 | Schering Corporation | Pyridine and pyridine N-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof |
| WO1993020063A1 (en) * | 1992-03-27 | 1993-10-14 | Schering Corporation | Unbridged bis-aryl carbinol derivatives, compositions and methods of use |
| TW381025B (en) * | 1993-08-05 | 2000-02-01 | Hoffmann La Roche | Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor |
| US6184234B1 (en) * | 1994-03-01 | 2001-02-06 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines |
| US6017931A (en) * | 1994-03-01 | 2000-01-25 | Fmc Corporation | Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
| US6030987A (en) * | 1996-05-17 | 2000-02-29 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines |
| US5639763A (en) * | 1994-03-01 | 1997-06-17 | Fmc Corporation | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines |
| HUP9802550A3 (en) * | 1995-05-19 | 2000-06-28 | Fmc Corp | Insecticidal n-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines |
| BR9707807A (en) * | 1996-03-01 | 1999-07-27 | Novo Nordisk As | Use of a pharmaceutical composition pharmaceutical composition process of treating diseases or disorders associated with the regulation of impaired appetite and use of a peptide |
| WO1999014203A1 (en) | 1997-09-16 | 1999-03-25 | Takeda Chemical Industries, Ltd. | Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs |
| EP1307264B1 (en) * | 2000-07-28 | 2004-10-20 | F. Hoffmann-La Roche Ag | New pharmaceutical composition |
| US20100064413A1 (en) * | 2008-03-14 | 2010-03-18 | Simply Weights, LLC | Exercise clothing and accessories |
| ES2525340T3 (en) * | 2008-04-29 | 2014-12-22 | F. Hoffmann-La Roche Ag | Trimethylammonium 4-butyrates as CPT2 inhibitors |
| AU2009242240B2 (en) * | 2008-04-29 | 2011-09-22 | F. Hoffmann-La Roche Ag | 4-dimethylaminobutyric acid derivatives |
| EP3737680A1 (en) | 2018-01-08 | 2020-11-18 | F. Hoffmann-La Roche AG | Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors |
| CN115989228A (en) | 2020-09-03 | 2023-04-18 | 豪夫迈·罗氏有限公司 | Heterocyclic compound |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4076717A (en) * | 1971-12-15 | 1978-02-28 | G. D. Searle & Co. | Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid |
| US3931197A (en) * | 1974-02-08 | 1976-01-06 | Richardson-Merrell Inc. | Substituted piperidine derivatives |
| US4650874A (en) * | 1984-11-26 | 1987-03-17 | G. D. Searle & Co. | N-(aralkoxybenzyl)-4(benzhydryl) piperidines |
-
1985
- 1985-10-07 US US06/785,113 patent/US4632925A/en not_active Expired - Fee Related
-
1986
- 1986-09-26 ZA ZA867375A patent/ZA867375B/en unknown
- 1986-10-03 DK DK475286A patent/DK168291B1/en active
- 1986-10-03 HU HU864167A patent/HU196200B/en not_active IP Right Cessation
- 1986-10-03 IL IL80232A patent/IL80232A0/en not_active IP Right Cessation
- 1986-10-03 CA CA000519718A patent/CA1281326C/en not_active Expired - Lifetime
- 1986-10-03 NZ NZ217798A patent/NZ217798A/en unknown
- 1986-10-03 AU AU63501/86A patent/AU593844B2/en not_active Ceased
- 1986-10-06 NO NO863978A patent/NO166127C/en unknown
- 1986-10-06 JP JP61236364A patent/JPH0633254B2/en not_active Expired - Lifetime
- 1986-10-06 IE IE263686A patent/IE59434B1/en not_active IP Right Cessation
- 1986-10-06 ES ES8602424A patent/ES2005074A6/en not_active Expired
- 1986-10-06 PT PT83495A patent/PT83495B/en not_active IP Right Cessation
- 1986-10-06 MC MC861851A patent/MC1769A1/en unknown
- 1986-10-06 DE DE8686113837T patent/DE3672134D1/en not_active Expired - Lifetime
- 1986-10-06 EP EP86113837A patent/EP0221376B1/en not_active Expired - Lifetime
- 1986-10-06 AT AT86113837T patent/ATE53997T1/en not_active IP Right Cessation
- 1986-10-07 KR KR1019860008388A patent/KR870003984A/en not_active Ceased
- 1986-10-07 PH PH34329A patent/PH24167A/en unknown
- 1986-10-07 GR GR862513A patent/GR862513B/en unknown
- 1986-10-07 FI FI864051A patent/FI85020C/en not_active IP Right Cessation
- 1986-10-23 AR AR86305473A patent/AR241422A1/en active
-
1993
- 1993-02-17 SG SG175/93A patent/SG17593G/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19950531 |