PT823428E - Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina - Google Patents
Derivados do acido neuraminico sua preparacao e sua utilizacao em medicinaInfo
- Publication number
- PT823428E PT823428E PT97305159T PT97305159T PT823428E PT 823428 E PT823428 E PT 823428E PT 97305159 T PT97305159 T PT 97305159T PT 97305159 T PT97305159 T PT 97305159T PT 823428 E PT823428 E PT 823428E
- Authority
- PT
- Portugal
- Prior art keywords
- formula
- medicine
- derivatives
- preparation
- neuraminic acid
- Prior art date
Links
- CERZMXAJYMMUDR-QBTAGHCHSA-N 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid Chemical class N[C@@H]1[C@@H](O)CC(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO CERZMXAJYMMUDR-QBTAGHCHSA-N 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 102000005348 Neuraminidase Human genes 0.000 abstract 1
- 108010006232 Neuraminidase Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 239000002911 sialidase inhibitor Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19186296 | 1996-07-22 | ||
| JP8688897 | 1997-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT823428E true PT823428E (pt) | 2002-04-29 |
Family
ID=26427962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97305159T PT823428E (pt) | 1996-07-22 | 1997-07-11 | Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0823428B1 (pt) |
| KR (1) | KR100506578B1 (pt) |
| CN (1) | CN1127494C (pt) |
| AT (1) | ATE211468T1 (pt) |
| AU (1) | AU700926B2 (pt) |
| CA (1) | CA2210492C (pt) |
| CZ (1) | CZ291960B6 (pt) |
| DE (1) | DE69709795T2 (pt) |
| DK (1) | DK0823428T3 (pt) |
| ES (1) | ES2167682T3 (pt) |
| HU (1) | HU223494B1 (pt) |
| ID (1) | ID17474A (pt) |
| IL (1) | IL121305A (pt) |
| MX (1) | MX9705559A (pt) |
| NO (1) | NO317704B1 (pt) |
| NZ (1) | NZ328353A (pt) |
| PT (1) | PT823428E (pt) |
| RU (1) | RU2124509C1 (pt) |
| TW (1) | TW418200B (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
| US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
| US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
| US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| TWI291462B (en) * | 2000-04-25 | 2007-12-21 | Daiichi Sankyo Co Ltd | Hydrate crystal of neuraminic acid compound |
| FR2809104B1 (fr) * | 2000-05-19 | 2002-08-02 | Univ Paris Curie | Procede de traitement de matiere vegetale, compositions comportant des derives du type n-acylglucosamine, utilisation de ces composes en tant qu'agents bio- protecteurs, et matiere vegetale traitee. |
| AU2001256759A1 (en) * | 2000-05-19 | 2001-11-26 | Sankyo Company Limited | Sialic acid derivatives |
| AUPR001000A0 (en) | 2000-09-08 | 2000-10-05 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| WO2002076980A1 (en) * | 2001-03-27 | 2002-10-03 | Sankyo Company, Limited | Sialic acid derivatives |
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| PL2123271T3 (pl) * | 2007-03-07 | 2012-03-30 | Daiichi Sankyo Co Ltd | Lek do leczenia grypy |
| TWI460182B (zh) * | 2007-04-11 | 2014-11-11 | Daiichi Sankyo Co Ltd | 原酸酯之製造方法 |
| KR100930963B1 (ko) * | 2008-02-26 | 2009-12-11 | 한국기계연구원 | 적층형 압전파이로트 밸브를 이용한 공조기용 팽창밸브 |
| JP2012510456A (ja) | 2008-11-28 | 2012-05-10 | シプラ・リミテッド | ザナミビルの製造方法及び該方法に使用するための中間体 |
| TWI491416B (zh) | 2008-12-24 | 2015-07-11 | Daiichi Sankyo Co Ltd | 吸入用乾燥粉末醫藥組成物 |
| AU2010247141A1 (en) | 2009-05-15 | 2011-12-15 | Redx Pharma Plc | Redox drug derivatives |
| CN102532080A (zh) * | 2010-12-29 | 2012-07-04 | 中国科学院上海药物研究所 | 新型唾液酸衍生物及其制备方法,包含该衍生物的药物组合物,以及其用途 |
| HK1199034A1 (en) * | 2011-12-16 | 2015-06-19 | Daiichi Sankyo Company, Limited | Method for producing neuraminic acid derivative |
| WO2015032357A1 (zh) * | 2013-09-09 | 2015-03-12 | 中国科学院上海有机化学研究所 | 扎那米韦和拉那米韦的中间体及其合成方法 |
| CN114843564B (zh) * | 2022-03-28 | 2023-08-25 | 电子科技大学 | 一种阴阳离子共掺杂的固体氧化物电池氧电极材料及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK282950B6 (sk) * | 1990-04-24 | 2003-01-09 | Biota Scientific Management Pty Ltd | Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze |
| CA2081068C (en) * | 1991-10-23 | 2005-11-29 | Laurence Mark Von Itzstein | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid |
| GB9312531D0 (en) * | 1993-06-17 | 1993-08-04 | Glaxo Group Ltd | Process |
| GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
| GB9400206D0 (en) * | 1994-01-07 | 1994-03-02 | Glaxo Group Ltd | Chemical compound |
| AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
| GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
-
1997
- 1997-07-11 AT AT97305159T patent/ATE211468T1/de active
- 1997-07-11 DE DE69709795T patent/DE69709795T2/de not_active Expired - Lifetime
- 1997-07-11 ES ES97305159T patent/ES2167682T3/es not_active Expired - Lifetime
- 1997-07-11 PT PT97305159T patent/PT823428E/pt unknown
- 1997-07-11 EP EP97305159A patent/EP0823428B1/en not_active Expired - Lifetime
- 1997-07-11 DK DK97305159T patent/DK0823428T3/da active
- 1997-07-14 IL IL12130597A patent/IL121305A/xx not_active IP Right Cessation
- 1997-07-15 CA CA002210492A patent/CA2210492C/en not_active Expired - Lifetime
- 1997-07-16 AU AU28662/97A patent/AU700926B2/en not_active Expired
- 1997-07-16 NZ NZ328353A patent/NZ328353A/en not_active IP Right Cessation
- 1997-07-21 TW TW086110312A patent/TW418200B/zh not_active IP Right Cessation
- 1997-07-21 RU RU97113367A patent/RU2124509C1/ru active
- 1997-07-21 NO NO19973363A patent/NO317704B1/no not_active IP Right Cessation
- 1997-07-21 ID IDP972509A patent/ID17474A/id unknown
- 1997-07-21 CZ CZ19972316A patent/CZ291960B6/cs not_active IP Right Cessation
- 1997-07-22 KR KR1019970034213A patent/KR100506578B1/ko not_active Expired - Lifetime
- 1997-07-22 MX MX9705559A patent/MX9705559A/es unknown
- 1997-07-22 CN CN97117883A patent/CN1127494C/zh not_active Expired - Lifetime
- 1997-07-22 HU HU9701270A patent/HU223494B1/hu active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2167682T3 (es) | 2002-05-16 |
| DE69709795D1 (de) | 2002-02-28 |
| DE69709795T2 (de) | 2002-09-26 |
| HU9701270D0 (en) | 1997-09-29 |
| IL121305A (en) | 2003-01-12 |
| DK0823428T3 (da) | 2002-02-18 |
| EP0823428B1 (en) | 2002-01-02 |
| CA2210492A1 (en) | 1998-01-22 |
| HK1007879A1 (en) | 1999-04-30 |
| RU2124509C1 (ru) | 1999-01-10 |
| CN1127494C (zh) | 2003-11-12 |
| HU223494B1 (hu) | 2004-08-30 |
| ATE211468T1 (de) | 2002-01-15 |
| AU700926B2 (en) | 1999-01-14 |
| CA2210492C (en) | 2002-10-29 |
| NO973363L (no) | 1998-01-23 |
| HUP9701270A3 (en) | 2002-08-28 |
| MX9705559A (es) | 1998-05-31 |
| AU2866297A (en) | 1998-07-02 |
| EP0823428A3 (en) | 1998-02-25 |
| NO317704B1 (no) | 2004-12-06 |
| CZ231697A3 (cs) | 1998-02-18 |
| HUP9701270A2 (hu) | 1999-09-28 |
| IL121305A0 (en) | 1998-01-04 |
| CN1172807A (zh) | 1998-02-11 |
| TW418200B (en) | 2001-01-11 |
| NZ328353A (en) | 1998-03-25 |
| EP0823428A2 (en) | 1998-02-11 |
| NO973363D0 (no) | 1997-07-21 |
| CZ291960B6 (cs) | 2003-06-18 |
| ID17474A (id) | 1998-01-08 |
| KR980009253A (ko) | 1998-04-30 |
| KR100506578B1 (ko) | 2005-12-26 |
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