PT603887E - Derivados de amina biciclicos - Google Patents
Derivados de amina biciclicosInfo
- Publication number
- PT603887E PT603887E PT93120802T PT93120802T PT603887E PT 603887 E PT603887 E PT 603887E PT 93120802 T PT93120802 T PT 93120802T PT 93120802 T PT93120802 T PT 93120802T PT 603887 E PT603887 E PT 603887E
- Authority
- PT
- Portugal
- Prior art keywords
- substituent
- binically
- atom
- amine derivatives
- hydrogen atom
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34603092 | 1992-12-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT603887E true PT603887E (pt) | 2004-02-27 |
Family
ID=18380663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT93120802T PT603887E (pt) | 1992-12-25 | 1993-12-23 | Derivados de amina biciclicos |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5654318A (pt) |
| EP (1) | EP0603887B1 (pt) |
| JP (1) | JP3268098B2 (pt) |
| KR (1) | KR100295483B1 (pt) |
| CN (1) | CN1037441C (pt) |
| AT (1) | ATE251157T1 (pt) |
| AU (1) | AU669948B2 (pt) |
| CA (1) | CA2112165C (pt) |
| DE (1) | DE69333223T2 (pt) |
| DK (1) | DK0603887T3 (pt) |
| ES (1) | ES2208636T3 (pt) |
| FI (1) | FI105031B (pt) |
| NO (1) | NO301165B1 (pt) |
| PH (1) | PH31587A (pt) |
| PT (1) | PT603887E (pt) |
| RU (1) | RU2125046C1 (pt) |
| TW (1) | TW264476B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0148277B1 (ko) * | 1993-01-18 | 1998-11-02 | 채영복 | 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법 |
| KR960004339A (ko) * | 1994-07-02 | 1996-02-23 | 임성기 | 신규한 퀴놀린계 화합물 및 그 의 제조방법 |
| WO1996011194A1 (en) * | 1994-10-06 | 1996-04-18 | Dainippon Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivative and intermediate for the synthesis of the same |
| DE19546249A1 (de) * | 1995-12-12 | 1997-06-19 | Bayer Ag | Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| WO1997031001A1 (de) * | 1996-02-23 | 1997-08-28 | Bayer Aktiengesellschaft | Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate |
| KR19990082534A (ko) * | 1996-02-27 | 1999-11-25 | 도모다께 다께시 | 피리돈카르복실산 유도체 및 그 합성중간체 |
| CN1103769C (zh) * | 1996-10-25 | 2003-03-26 | 第一制药株式会社 | 三环胺衍生物 |
| DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
| DE19821039A1 (de) * | 1998-05-11 | 1999-11-18 | Bayer Ag | Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan |
| DE19931115A1 (de) * | 1999-07-06 | 2001-01-11 | Bayer Ag | Racemisierung von R, S-Dioxo-Benzylpyrrolopiperidin |
| DK1262477T3 (da) * | 2000-02-09 | 2008-12-01 | Daiichi Sankyo Co Ltd | Antibakterielle midler, der er virksomme mod syrefaste bakterier og indeholder pyridoncarboxylsyrer som aktiv ingrediens |
| MY137020A (en) | 2000-04-27 | 2008-12-31 | Abbott Lab | Diazabicyclic central nervous system active agents |
| US6809105B2 (en) | 2000-04-27 | 2004-10-26 | Abbott Laboratories | Diazabicyclic central nervous system active agents |
| DE10022369A1 (de) | 2000-05-08 | 2001-11-15 | Bayer Ag | Verfahren zur Herstellung von Piperidinen |
| EP1888066B1 (en) * | 2005-05-25 | 2012-01-11 | Merck Sharp & Dohme Corp. | Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
| CN102101861B (zh) * | 2008-07-01 | 2012-07-18 | 韶远化学科技（上海）有限公司 | 含氮双杂环医药中间体的合成及工艺方法 |
| NZ596492A (en) | 2009-05-15 | 2013-08-30 | Redx Pharma Ltd | Redox drug derivatives |
| CN102675308A (zh) * | 2011-03-17 | 2012-09-19 | 苏州中科天马肽工程中心有限公司 | 一种制备8-苄基-2,8-二氮杂二环[4.3.0]壬烷的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT294090B (de) * | 1969-04-22 | 1971-11-10 | Degussa | Verfahren zur Herstellung von neuen Aminopyridinen, von deren optisch aktiven bzw. diastereomeren Formen, deren Salzen und deren quartären Verbindungen |
| NZ210805A (en) * | 1984-01-19 | 1988-04-29 | Norton Co | Aluminous abrasive grits or shaped bodies |
| DE3576335D1 (de) * | 1984-12-14 | 1990-04-12 | Daiichi Seiyaku Co | Chinolincarbonsaeure-derivate. |
| DE3509546A1 (de) * | 1985-03-16 | 1986-09-25 | Bayer Ag, 5090 Leverkusen | 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| IL90062A (en) * | 1988-04-27 | 1994-10-07 | Daiichi Seiyaku Co | Pyridonecarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
| KR910009330B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
| CA2030217A1 (en) * | 1989-11-21 | 1991-05-22 | Jun Imose | Pyridone-carboxylic acid derivatives useful as veterinary medicines |
| JPH03188080A (ja) * | 1989-12-15 | 1991-08-16 | Banyu Pharmaceut Co Ltd | ピリドンカルボン酸誘導体 |
| DE4032560A1 (de) * | 1990-10-13 | 1992-04-16 | Bayer Ag | 7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate |
| ATE196135T1 (de) * | 1991-05-28 | 2000-09-15 | Daiichi Seiyaku Co | Pyridoncarbonsäurederivate |
| TW209865B (pt) * | 1992-01-10 | 1993-07-21 | Bayer Ag | |
| DE4230804A1 (de) * | 1992-09-15 | 1994-03-17 | Bayer Ag | 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate |
-
1993
- 1993-12-22 CA CA002112165A patent/CA2112165C/en not_active Expired - Fee Related
- 1993-12-22 JP JP32301193A patent/JP3268098B2/ja not_active Expired - Fee Related
- 1993-12-22 NO NO934753A patent/NO301165B1/no not_active IP Right Cessation
- 1993-12-23 US US08/172,233 patent/US5654318A/en not_active Expired - Lifetime
- 1993-12-23 PT PT93120802T patent/PT603887E/pt unknown
- 1993-12-23 TW TW082110919A patent/TW264476B/zh active
- 1993-12-23 FI FI935830A patent/FI105031B/fi not_active IP Right Cessation
- 1993-12-23 AT AT93120802T patent/ATE251157T1/de not_active IP Right Cessation
- 1993-12-23 EP EP93120802A patent/EP0603887B1/en not_active Expired - Lifetime
- 1993-12-23 DE DE69333223T patent/DE69333223T2/de not_active Expired - Fee Related
- 1993-12-23 ES ES93120802T patent/ES2208636T3/es not_active Expired - Lifetime
- 1993-12-23 DK DK93120802T patent/DK0603887T3/da active
- 1993-12-23 RU RU93056853A patent/RU2125046C1/ru not_active IP Right Cessation
- 1993-12-23 AU AU52695/93A patent/AU669948B2/en not_active Ceased
- 1993-12-24 KR KR1019930029472A patent/KR100295483B1/ko not_active Expired - Fee Related
- 1993-12-24 PH PH47546A patent/PH31587A/en unknown
- 1993-12-25 CN CN93121757A patent/CN1037441C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO301165B1 (no) | 1997-09-22 |
| NO934753L (no) | 1994-06-27 |
| FI105031B (fi) | 2000-05-31 |
| NO934753D0 (no) | 1993-12-22 |
| FI935830L (fi) | 1994-06-26 |
| AU669948B2 (en) | 1996-06-27 |
| PH31587A (en) | 1998-11-03 |
| CN1037441C (zh) | 1998-02-18 |
| TW264476B (pt) | 1995-12-01 |
| KR100295483B1 (ko) | 2001-09-17 |
| CN1095068A (zh) | 1994-11-16 |
| ATE251157T1 (de) | 2003-10-15 |
| JPH06239857A (ja) | 1994-08-30 |
| DE69333223T2 (de) | 2004-08-05 |
| CA2112165A1 (en) | 1994-06-26 |
| FI935830A0 (fi) | 1993-12-23 |
| JP3268098B2 (ja) | 2002-03-25 |
| US5654318A (en) | 1997-08-05 |
| EP0603887A2 (en) | 1994-06-29 |
| DK0603887T3 (da) | 2004-01-26 |
| RU2125046C1 (ru) | 1999-01-20 |
| DE69333223D1 (de) | 2003-11-06 |
| CA2112165C (en) | 2003-04-08 |
| EP0603887A3 (en) | 1995-04-26 |
| KR940014397A (ko) | 1994-07-18 |
| AU5269593A (en) | 1994-07-07 |
| ES2208636T3 (es) | 2004-06-16 |
| EP0603887B1 (en) | 2003-10-01 |
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