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PT3101660T - Processo de produção de gálio-68 através de irradiação de um alvo em solução - Google Patents

Processo de produção de gálio-68 através de irradiação de um alvo em solução

Info

Publication number
PT3101660T
PT3101660T PT151708542T PT15170854T PT3101660T PT 3101660 T PT3101660 T PT 3101660T PT 151708542 T PT151708542 T PT 151708542T PT 15170854 T PT15170854 T PT 15170854T PT 3101660 T PT3101660 T PT 3101660T
Authority
PT
Portugal
Prior art keywords
irradiation
solution target
producing gallium
gallium
producing
Prior art date
Application number
PT151708542T
Other languages
English (en)
Inventor
Vitor H Alves
Alves Francisco
J Abrunhosa Antero
Original Assignee
Ion Beam Appl Sa
Univ De Coimbra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ion Beam Appl Sa, Univ De Coimbra filed Critical Ion Beam Appl Sa
Publication of PT3101660T publication Critical patent/PT3101660T/pt

Links

Classifications

    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001Recovery of specific isotopes from irradiated targets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/04Processes using organic exchangers
    • B01J39/05Processes using organic exchangers in the strongly acidic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16Organic material
    • B01J39/18Macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/04Processes using organic exchangers
    • B01J41/05Processes using organic exchangers in the strongly basic form
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/08Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/12Macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00Ion-exchange processes in general; Apparatus therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22BPRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B58/00Obtaining gallium or indium
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001Recovery of specific isotopes from irradiated targets
    • G21G2001/0021Gallium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Manufacturing & Machinery (AREA)
  • Metallurgy (AREA)
  • Mechanical Engineering (AREA)
  • Materials Engineering (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Particle Accelerators (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT151708542T 2015-06-05 2015-06-05 Processo de produção de gálio-68 através de irradiação de um alvo em solução PT3101660T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15170854.2A EP3101660B1 (en) 2015-06-05 2015-06-05 Process for producing gallium-68 through the irradiation of a solution target

Publications (1)

Publication Number Publication Date
PT3101660T true PT3101660T (pt) 2017-09-18

Family

ID=53298231

Family Applications (1)

Application Number Title Priority Date Filing Date
PT151708542T PT3101660T (pt) 2015-06-05 2015-06-05 Processo de produção de gálio-68 através de irradiação de um alvo em solução

Country Status (5)

Country Link
US (2) US20160358683A1 (pt)
EP (1) EP3101660B1 (pt)
JP (1) JP6632472B2 (pt)
CA (1) CA2932118C (pt)
PT (1) PT3101660T (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6534581B2 (ja) * 2015-08-18 2019-06-26 日本メジフィジックス株式会社 放射性ガリウムを製造する方法、当該放射性ガリウムを含む医薬を製造する方法、亜鉛安定同位体を回収する方法
BR112020002016A2 (pt) * 2017-07-31 2020-07-28 Stefan Zeisler sistema, aparelho e método para produzir radioisótopos de gálio em aceleradores de partículas usando alvos sólidos e composição de ga-68 produzida pelos mesmos
CN108126648A (zh) * 2018-01-04 2018-06-08 江苏华益科技有限公司 一种放射性药物的自动传输装置及方法
WO2020030659A1 (en) 2018-08-07 2020-02-13 Technical University Of Denmark Separation of radiometals
GB201814291D0 (en) * 2018-09-03 2018-10-17 Univ Oslo Process for the production of gallium radionculides
CA3122862A1 (en) * 2018-12-11 2020-06-18 Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Et Genie S.E.C. Processes and systems for producing and/or purifying gallium-68
JP2022551697A (ja) 2019-10-12 2022-12-13 アームズ プロダクツ,インコーポレイテッド ガリウム68の単離のためのシステムおよび方法
CN112614607A (zh) * 2020-12-02 2021-04-06 中广核研究院有限公司 放射性核素锰-54的制备方法
CN113019279A (zh) * 2021-03-11 2021-06-25 山西医科大学第一医院 一种放射性药物制备的自动合成装置及其使用方法
CN113144225A (zh) * 2021-03-30 2021-07-23 广东回旋医药科技股份有限公司 一种高放射性核纯度的68Ga-GaCl3溶液的制备方法及应用
CN113200564A (zh) * 2021-04-09 2021-08-03 广东回旋医药科技股份有限公司 一种[68Zn]硝酸锌靶溶液的制备方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1216715A1 (fr) 2000-12-22 2002-06-26 Ion Beam Applications S.A. Dispositif de synthèse de produits radiopharmaceutiques
EP1775001A1 (en) * 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
US7586102B2 (en) * 2006-08-14 2009-09-08 Board Of Regents The University Of Texas System Automated system for formulating radiopharmaceuticals
US7728310B2 (en) * 2007-05-10 2010-06-01 Los Alamos National Security, Llc Method for the chemical separation of GE-68 from its daughter Ga-68
JP2009229201A (ja) * 2008-03-21 2009-10-08 Institute Of Physical & Chemical Research Gaのイオンを単離する方法とそのための装置
TWI397421B (zh) * 2010-07-14 2013-06-01 Inst Nuclear Energy Res Atomic Energy Council 鎵-68放射性同位素產生裝置及其方法
BE1019556A3 (fr) 2010-10-27 2012-08-07 Ion Beam Applic Sa Dispositif destine a la production de radioisotopes.
US9269467B2 (en) * 2011-06-02 2016-02-23 Nigel Raymond Stevenson General radioisotope production method employing PET-style target systems
EP3142709B1 (en) * 2014-05-15 2025-07-30 Mayo Foundation for Medical Education and Research Synthesis sytem comprising a solution target for cyclotron production of radiometals and associated method

Also Published As

Publication number Publication date
EP3101660B1 (en) 2017-08-09
CA2932118A1 (en) 2016-12-05
CA2932118C (en) 2022-09-06
EP3101660A1 (en) 2016-12-07
JP2017003577A (ja) 2017-01-05
US20160358683A1 (en) 2016-12-08
US10600528B2 (en) 2020-03-24
US20190013108A1 (en) 2019-01-10
JP6632472B2 (ja) 2020-01-22

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