PT3019178T - Inibidores de adamts4 ou adamts5 para utilização na prevenção ou tratamento de remodelação cardíaca e insuficiência cardíaca crónica - Google Patents
Inibidores de adamts4 ou adamts5 para utilização na prevenção ou tratamento de remodelação cardíaca e insuficiência cardíaca crónicaInfo
- Publication number
- PT3019178T PT3019178T PT147364178T PT14736417T PT3019178T PT 3019178 T PT3019178 T PT 3019178T PT 147364178 T PT147364178 T PT 147364178T PT 14736417 T PT14736417 T PT 14736417T PT 3019178 T PT3019178 T PT 3019178T
- Authority
- PT
- Portugal
- Prior art keywords
- adamts4
- adamts5
- inhibitors
- preventing
- heart failure
- Prior art date
Links
- 206010007558 Cardiac failure chronic Diseases 0.000 title 1
- 230000000747 cardiac effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000007634 remodeling Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1312311.2A GB201312311D0 (en) | 2013-07-09 | 2013-07-09 | Uses of enzyme inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3019178T true PT3019178T (pt) | 2021-03-01 |
Family
ID=49033561
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT147364178T PT3019178T (pt) | 2013-07-09 | 2014-07-09 | Inibidores de adamts4 ou adamts5 para utilização na prevenção ou tratamento de remodelação cardíaca e insuficiência cardíaca crónica |
| PT201884749T PT3756667T (pt) | 2013-07-09 | 2014-07-09 | Inibidores de adamts4 ou adamts5 para utilização na prevenção ou tratamento de remodelação cardíaca e insuficiência cardíaca crónica |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT201884749T PT3756667T (pt) | 2013-07-09 | 2014-07-09 | Inibidores de adamts4 ou adamts5 para utilização na prevenção ou tratamento de remodelação cardíaca e insuficiência cardíaca crónica |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10322143B2 (pt) |
| EP (2) | EP3756667B1 (pt) |
| DK (2) | DK3019178T3 (pt) |
| ES (2) | ES2940790T3 (pt) |
| FI (1) | FI3756667T3 (pt) |
| GB (1) | GB201312311D0 (pt) |
| PT (2) | PT3019178T (pt) |
| WO (1) | WO2015004209A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115792237A (zh) * | 2021-09-09 | 2023-03-14 | 中国中医科学院中药研究所 | 一种早期预测心力衰竭的生物标志物 |
| WO2023070164A1 (en) * | 2021-10-28 | 2023-05-04 | Paradigm Biopharmaceuticals Ltd | Treatment of heart failure with preserved ejection fraction |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000057444A (ko) * | 1996-12-09 | 2000-09-15 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 심기능부전 및 심실확장의 치료 및 예방 방법 |
| JP2005515779A (ja) * | 2002-01-31 | 2005-06-02 | ワイス | アグレカナーゼ分子 |
| WO2005061459A1 (en) * | 2003-12-04 | 2005-07-07 | Wyeth | Biaryl sulfonamides and methods for using same |
| US20070155737A1 (en) * | 2005-05-20 | 2007-07-05 | Alantos Pharmaceuticals, Inc. | Heterobicyclic metalloprotease inhibitors |
| BRPI0613030A2 (pt) | 2005-07-11 | 2012-01-03 | Wyeth Corp | composto de fàrmula i; composto ou sal farmaceuticamente aceitÁvel do composto; mÉtodo para modular a atividade de uma metaloproteinase em animal que dele necessite; composiÇço; mÉtodo para tratamento de um distérbio relacionado a metaloproteinase em animal que dele necessite; mÉtodo de sintetizar um composto; composto de fàrmula ii |
| US20090318342A1 (en) * | 2005-07-29 | 2009-12-24 | Imperial Innovations Limited | Compounds |
| US8871741B2 (en) * | 2010-01-15 | 2014-10-28 | Icahn School Of Medicine At Mount Sinai | Inhibition of TNF-α induced activation of NFKB by pentosan polysulfate |
-
2013
- 2013-07-09 GB GBGB1312311.2A patent/GB201312311D0/en not_active Ceased
-
2014
- 2014-07-09 ES ES20188474T patent/ES2940790T3/es active Active
- 2014-07-09 PT PT147364178T patent/PT3019178T/pt unknown
- 2014-07-09 ES ES14736417T patent/ES2854924T3/es active Active
- 2014-07-09 WO PCT/EP2014/064761 patent/WO2015004209A1/en not_active Ceased
- 2014-07-09 DK DK14736417.8T patent/DK3019178T3/da active
- 2014-07-09 EP EP20188474.9A patent/EP3756667B1/en active Active
- 2014-07-09 EP EP14736417.8A patent/EP3019178B1/en active Active
- 2014-07-09 FI FIEP20188474.9T patent/FI3756667T3/fi active
- 2014-07-09 DK DK20188474.9T patent/DK3756667T3/da active
- 2014-07-09 US US14/903,624 patent/US10322143B2/en active Active
- 2014-07-09 PT PT201884749T patent/PT3756667T/pt unknown
-
2019
- 2019-05-06 US US16/403,882 patent/US10744155B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3756667B1 (en) | 2023-01-25 |
| DK3756667T3 (da) | 2023-03-27 |
| US10744155B2 (en) | 2020-08-18 |
| FI3756667T3 (fi) | 2023-04-04 |
| DK3019178T3 (da) | 2021-03-01 |
| EP3019178B1 (en) | 2020-12-09 |
| GB201312311D0 (en) | 2013-08-21 |
| ES2940790T3 (es) | 2023-05-11 |
| US20190282606A1 (en) | 2019-09-19 |
| WO2015004209A1 (en) | 2015-01-15 |
| EP3756667A1 (en) | 2020-12-30 |
| EP3019178A1 (en) | 2016-05-18 |
| ES2854924T3 (es) | 2021-09-23 |
| US20160158271A1 (en) | 2016-06-09 |
| PT3756667T (pt) | 2023-03-30 |
| US10322143B2 (en) | 2019-06-18 |
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