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PT2061561E - Composições para tratar o cancro - Google Patents

Composições para tratar o cancro

Info

Publication number
PT2061561E
PT2061561E PT78373263T PT07837326T PT2061561E PT 2061561 E PT2061561 E PT 2061561E PT 78373263 T PT78373263 T PT 78373263T PT 07837326 T PT07837326 T PT 07837326T PT 2061561 E PT2061561 E PT 2061561E
Authority
PT
Portugal
Prior art keywords
compositions
treating cancer
cancer
hydroxylase
steroid
Prior art date
Application number
PT78373263T
Other languages
English (en)
Inventor
Alan H Auerbach
Arie S Belldegrun
Original Assignee
Janssen Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38916904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2061561(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Oncology Inc filed Critical Janssen Oncology Inc
Publication of PT2061561E publication Critical patent/PT2061561E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT78373263T 2006-08-25 2007-08-23 Composições para tratar o cancro PT2061561E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92150606P 2006-08-25 2006-08-25

Publications (1)

Publication Number Publication Date
PT2061561E true PT2061561E (pt) 2013-10-09

Family

ID=38916904

Family Applications (2)

Application Number Title Priority Date Filing Date
PT78373263T PT2061561E (pt) 2006-08-25 2007-08-23 Composições para tratar o cancro
PT121605869T PT2478907T (pt) 2006-08-25 2007-08-23 Composições para tratar o cancro

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT121605869T PT2478907T (pt) 2006-08-25 2007-08-23 Composições para tratar o cancro

Country Status (20)

Country Link
EP (3) EP2061561B1 (pt)
JP (10) JP2010501575A (pt)
KR (4) KR20180003636A (pt)
CN (2) CN101528308A (pt)
AU (6) AU2007287098C1 (pt)
CA (1) CA2661422C (pt)
CY (2) CY1115477T1 (pt)
DK (2) DK2061561T3 (pt)
ES (2) ES2428634T3 (pt)
HR (2) HRP20130961T1 (pt)
HU (1) HUE054495T2 (pt)
IL (3) IL197211A0 (pt)
LT (1) LT2478907T (pt)
NO (2) NO20091190L (pt)
NZ (1) NZ597830A (pt)
PL (2) PL2061561T3 (pt)
PT (2) PT2061561E (pt)
RS (2) RS52956B (pt)
SI (2) SI2061561T1 (pt)
WO (1) WO2008024484A1 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180003636A (ko) * 2006-08-25 2018-01-09 코우가 바이오테크놀로지, 인크. 암을 치료하기 위한 방법 및 조성물
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
US20090124587A1 (en) * 2007-07-12 2009-05-14 Auerbach Alan H METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS
AU2008319767B8 (en) * 2007-10-29 2014-01-09 Takeda Pharmaceutical Company Limited Pyrrolo [1,2-C] imidazole derivatives for use in the prophylaxis or treatment of cancer which is refractory to known cancer therapies
CN102558274B (zh) * 2010-12-08 2014-10-15 深圳万乐药业有限公司 一种适合工业化生产醋酸阿比特龙的合成方法
CN102558275A (zh) * 2010-12-20 2012-07-11 天津药物研究院 α型多晶型醋酸阿比特龙结晶、其制备方法、用途和药物组合物
MX356704B (es) 2011-01-11 2018-06-11 Novartis Ag Combinación.
WO2012135753A1 (en) 2011-04-01 2012-10-04 Genentech, Inc. Combinations of akt inhibitor compounds and erlotinib, and methods of use
US20120295932A1 (en) * 2011-05-17 2012-11-22 Western Connecticut Health Network, Inc. Method for the treatment of cancer
CN103070828B (zh) * 2011-10-26 2016-01-27 山东新时代药业有限公司 一种含醋酸阿比特龙的固体分散体、片剂及其制备方法
CN102336801B (zh) * 2011-10-31 2013-05-15 南京卡文迪许生物工程技术有限公司 醋酸阿比特龙多晶型物和药用组合物
GB201207886D0 (en) * 2012-05-04 2012-06-20 Jagotec Ag Improvements in or relating to organic compounds
JP2015518888A (ja) * 2012-06-06 2015-07-06 ノバルティス アーゲー 腫瘍疾患を治療するための１７−アルファ−ヒドロキシラーゼ（ｃ１７，２０−リアーゼ）インヒビターと特定のｐｉ−３ｋインヒビターとの組み合わせ
SG10201912719TA (en) 2012-09-26 2020-02-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
CN103800296A (zh) * 2012-11-13 2014-05-21 重庆医药工业研究院有限责任公司 一种稳定的阿比特龙口服固体药物组合物及其制备方法
JOP20200097A1 (ar) * 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
SG11201507681PA (en) * 2013-03-15 2015-10-29 Iceutica Inc Abiraterone acetate formulation
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
AU2014248001A1 (en) * 2013-04-04 2015-11-19 Exelixis, Inc. Drug combinations to treat cancer
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
EP3052098B1 (en) * 2013-10-01 2020-12-02 Novartis AG Enzalutamide in combination with afuresertib for the treatment of prostate cancer
BR112016006976A2 (pt) * 2013-10-01 2017-08-01 Novartis Ag combinação
CN104546745A (zh) * 2013-10-14 2015-04-29 深圳海王药业有限公司 醋酸阿比特龙的片剂组合物及其制备工艺
EP3824908A1 (en) * 2015-04-10 2021-05-26 Capsugel Belgium NV Abiraterone acetate lipid formulations
SI3490560T1 (sl) 2016-07-29 2025-04-30 Janssen Pharmaceutica, N.V. Niraparib za uporabo pri metodi zdravljenja raka prostate
JOP20190244A1 (ar) * 2017-04-13 2019-10-13 Janssen Pharmaceutica Nv تركيبة علاجية لسرطان البروستاتا
JP7201694B2 (ja) 2017-10-16 2023-01-10 アラゴン ファーマシューティカルズ，インコーポレイテッド 非転移性去勢抵抗性前立腺癌の治療のための抗アンドロゲン剤
CN109718198A (zh) * 2017-10-30 2019-05-07 浙江京新药业股份有限公司 一种治疗前列腺癌的注射剂及其制备方法
EP4286006A3 (en) * 2019-03-06 2024-03-20 Propella Therapeutics, Inc. Abiraterone prodrugs
WO2021031991A1 (zh) * 2019-08-16 2021-02-25 中国科学院分子细胞科学卓越创新中心 治疗激素依赖性疾病及减少激素依赖性疾病患者药物耐受的组合物和方法
IL297338A (en) * 2020-04-16 2022-12-01 Tavanta Therapeutics Hungary Incorporated Methods and compositions for treating prostate cancer
CN114560903B (zh) * 2022-03-09 2023-08-01 绍兴市上虞区武汉理工大学高等研究院 一种阿比特龙衍生物的制备方法及其细胞毒性评价
LU506495B1 (en) 2024-03-01 2025-09-01 Alfasan Nederland B V 17alpha-HYDROXYLASE/17,20-LYASE (CYP17A1) INHIBITORS FOR THE TREATMENT OF SPONTANEOUS HYPERADRENOCORTICISM IN DOGS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2132449C (en) 1992-03-31 2002-09-10 Susan E. Barrie 17 - substituted steroids useful in cancer treatment
US5604213A (en) 1992-03-31 1997-02-18 British Technology Group Limited 17-substituted steroids useful in cancer treatment
EP1276482B1 (en) * 2000-03-02 2008-01-16 University Of Pittsburgh Of The Commonwealth System Of Higher Education Combination chemotherapy
EP1351678A2 (en) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
DK1556058T3 (da) * 2002-10-23 2008-03-03 Pantarhei Bioscience Bv Farmaceutiske præparater omfattende östetrolderivater til anvendelse i cancerterapi
WO2004062620A2 (en) * 2003-01-13 2004-07-29 Cedars-Sinai Medical Center Paricalcitol as a chemotherapeutic agent
US20060030608A1 (en) * 2004-08-04 2006-02-09 Boehringer Ingelheim Pharmaceuticals, Inc. Anti aromatase compounds pharmaceutical compositions and uses thereof
GB0418900D0 (en) * 2004-08-24 2004-09-29 Btg Int Ltd Novel salt forms
KR20180003636A (ko) 2006-08-25 2018-01-09 코우가 바이오테크놀로지, 인크. 암을 치료하기 위한 방법 및 조성물

Also Published As

Publication number Publication date
RS52956B (sr) 2014-02-28
JP2019059750A (ja) 2019-04-18
AU2018271331A1 (en) 2018-12-20
JP2024164147A (ja) 2024-11-26
JP6445123B2 (ja) 2018-12-26
JP6740497B2 (ja) 2020-08-12
KR20200125776A (ko) 2020-11-04
SI2478907T1 (sl) 2021-08-31
HK1131577A1 (en) 2010-01-29
CA2661422A1 (en) 2008-02-28
PT2478907T (pt) 2021-05-26
AU2007287098B2 (en) 2013-08-15
PL2478907T3 (pl) 2021-10-25
CA2661422C (en) 2017-06-27
ES2428634T3 (es) 2013-11-08
SI2061561T1 (sl) 2013-11-29
AU2007287098C1 (en) 2018-03-15
JP6053279B2 (ja) 2016-12-27
DK2478907T3 (da) 2021-05-25
JP2015110577A (ja) 2015-06-18
AU2021201649A1 (en) 2021-04-08
EP2061561B1 (en) 2013-07-10
ES2869343T3 (es) 2021-10-25
CY1115477T1 (el) 2017-01-04
KR20150108946A (ko) 2015-09-30
JP2022185091A (ja) 2022-12-13
AU2022206696A1 (en) 2022-08-11
NO20200775A1 (no) 2009-03-20
JP2020114851A (ja) 2020-07-30
EP2478907B1 (en) 2021-04-14
WO2008024484A1 (en) 2008-02-28
AU2015221447B9 (en) 2017-07-20
LT2478907T (lt) 2021-06-25
JP2010501575A (ja) 2010-01-21
KR20090059126A (ko) 2009-06-10
AU2015221447A1 (en) 2015-09-17
JP2012082215A (ja) 2012-04-26
RS62034B1 (sr) 2021-07-30
PL2061561T3 (pl) 2013-12-31
AU2015221447B2 (en) 2016-12-15
IL227746A0 (en) 2013-09-30
CN104306977A (zh) 2015-01-28
CY1124221T1 (el) 2022-05-27
KR20180003636A (ko) 2018-01-09
IL257681A (en) 2018-04-30
DK2061561T3 (da) 2013-10-07
JP2017052791A (ja) 2017-03-16
JP2018065859A (ja) 2018-04-26
NZ597830A (en) 2013-02-22
AU2007287098A1 (en) 2008-02-28
HRP20130961T1 (hr) 2013-11-22
EP2478907A2 (en) 2012-07-25
HUE054495T2 (hu) 2021-09-28
EP2061561A1 (en) 2009-05-27
NO20091190L (no) 2009-03-20
HRP20210670T1 (hr) 2021-06-11
EP2478907A3 (en) 2012-08-01
JP2021038252A (ja) 2021-03-11
EP3804730A1 (en) 2021-04-14
AU2017201764A1 (en) 2017-04-06
CN101528308A (zh) 2009-09-09
IL197211A0 (en) 2009-12-24

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