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PT1863458T - Sistema solvente para potenciar a solubilidade de agentes farmacêuticos - Google Patents

Sistema solvente para potenciar a solubilidade de agentes farmacêuticos

Info

Publication number
PT1863458T
PT1863458T PT67370189T PT06737018T PT1863458T PT 1863458 T PT1863458 T PT 1863458T PT 67370189 T PT67370189 T PT 67370189T PT 06737018 T PT06737018 T PT 06737018T PT 1863458 T PT1863458 T PT 1863458T
Authority
PT
Portugal
Prior art keywords
potentiating
solubility
solvent system
pharmaceutical agents
pharmaceutical
Prior art date
Application number
PT67370189T
Other languages
English (en)
Inventor
A Fatmi Aqeel
Chidambaram Nachiappan
Original Assignee
Banner Life Sciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36581722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1863458(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Banner Life Sciences Llc filed Critical Banner Life Sciences Llc
Publication of PT1863458T publication Critical patent/PT1863458T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT67370189T 2005-03-08 2006-03-06 Sistema solvente para potenciar a solubilidade de agentes farmacêuticos PT1863458T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65967905P 2005-03-08 2005-03-08

Publications (1)

Publication Number Publication Date
PT1863458T true PT1863458T (pt) 2016-12-20

Family

ID=36581722

Family Applications (1)

Application Number Title Priority Date Filing Date
PT67370189T PT1863458T (pt) 2005-03-08 2006-03-06 Sistema solvente para potenciar a solubilidade de agentes farmacêuticos

Country Status (14)

Country Link
US (8) US20070053868A1 (pt)
EP (2) EP1863458B2 (pt)
CN (2) CN102940887B (pt)
CA (1) CA2600023C (pt)
CY (1) CY1118321T1 (pt)
DK (1) DK1863458T4 (pt)
ES (1) ES2606767T5 (pt)
HU (1) HUE030784T2 (pt)
LT (1) LT1863458T (pt)
MX (1) MX2007011039A (pt)
PL (1) PL1863458T5 (pt)
PT (1) PT1863458T (pt)
SI (1) SI1863458T2 (pt)
WO (1) WO2006096580A1 (pt)

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* Cited by examiner, † Cited by third party
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US20070053868A1 (en) 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents
WO2008070950A1 (en) * 2006-12-13 2008-06-19 Laboratoires Mauves Inc. Pharmaceutical solution formulations for encapsulation into gelatin capsules or other dosage forms
US20090104236A1 (en) * 2007-10-18 2009-04-23 Pharmaceutics International, Inc. Pharmaceutical solid hybrids
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
US20110052679A1 (en) * 2009-08-25 2011-03-03 Pharmaceutics International, Inc. Solid naproxen concentrates and related dosage forms
CA2690488C (en) * 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
CN103957886B (zh) * 2011-08-04 2016-03-30 奥默罗斯公司 稳定的抗炎注射溶液剂
CN103239711B (zh) * 2013-05-24 2015-08-05 成都天台山制药有限公司 曲普瑞林注射液和制法
US10772842B2 (en) 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
WO2015157150A1 (en) 2014-04-07 2015-10-15 Banner Life Sciences Llc Opioid abuse-deterrent controlled release formulations
CN104083339A (zh) * 2014-08-04 2014-10-08 人福普克药业（武汉）有限公司 萘普生钠软胶囊及其制备方法
US20160243044A1 (en) * 2015-02-20 2016-08-25 Enspire Group LLC Soft gelatin capsules containing fexofenadine
CA2978269A1 (en) * 2015-03-02 2016-09-09 Bionpharma Healthcare Llc Immediate release soluble ibuprofen compositions
US10182993B2 (en) 2015-04-06 2019-01-22 Patheon Softgels Inc. Compositions for colonic delivery of drugs
TWI620577B (zh) * 2016-11-23 2018-04-11 乙醯胺酚及曲馬多共溶複方止痛口服液
BR112021005923A2 (pt) 2018-10-16 2021-06-29 Bayer Healthcare Llc cápsulas de gelatina mole com matriz de enchimento polimérica sólida ou semelhante a gel
US20220202751A1 (en) * 2019-04-26 2022-06-30 R.P. Scherer Technologies, Llc Mini softgel naproxen composition
CA3207235A1 (en) * 2021-01-11 2022-07-14 Bayer Healthcare Llc Concentrated liquid gel formulations containing naproxen salts

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3035973A (en) 1958-08-01 1962-05-22 Lloyd Brothers Inc Gelatin capsule containing calcium dioctyl sulfosuccinate
US5071643A (en) 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US5141961A (en) 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
JP3121080B2 (ja) * 1991-12-19 2000-12-25 アール・ピー・シーラー コーポレイション カプセル封入用溶液
US5505961A (en) 1993-08-05 1996-04-09 R. P. Scherer Corporation Gelatin capsules containing a highly concentrated acetaminophen solution
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
US5484606A (en) * 1994-01-24 1996-01-16 The Procter & Gamble Company Process for reducing the precipitation of difficulty soluble pharmaceutical actives
US5484608A (en) * 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
AU2517095A (en) * 1994-05-19 1995-12-18 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5641512A (en) 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US5843469A (en) * 1997-04-11 1998-12-01 Mcentee; William J. Lipid soluble forms of thiamine for prevention and treatment of age-related cognitive impairment of the nervous system
US6066339A (en) 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
DE69940769D1 (de) 1998-01-20 2009-06-04 Applied Analytical Ind Inc Orale flüssige zusammensetzungen
US6183779B1 (en) * 1999-03-22 2001-02-06 Pharmascience Inc. Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
US20030216423A1 (en) * 2000-05-24 2003-11-20 Sergio Ulloa Stable liquid and solid formulations
US20020022058A1 (en) * 2000-07-08 2002-02-21 Lovercheck Dale R. Unit dose of material in system and method
US6387400B1 (en) 2000-08-29 2002-05-14 R.P. Scherer Technologies, Inc. Process for preparing pharmaceutical compositions for use with soft gelatin formulations
US7101572B2 (en) 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
US6689382B2 (en) 2002-05-15 2004-02-10 Procaps S.A. Soft shell gelatin capsules containing non-steroidal anti-inflammatories
CA2510465A1 (en) 2002-12-18 2004-07-08 Pain Therapeutics Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
JP2006514119A (ja) * 2003-02-12 2006-04-27 アール アンド ピー コリア カンパニー リミテッド 溶解率が向上した難溶性薬剤の溶媒系
CA2554243A1 (en) * 2004-01-20 2005-08-11 Stiefel Laboratories, Inc. Dermatologic soft gel compositions
US8231896B2 (en) * 2004-11-08 2012-07-31 R.P. Scherer Technologies, Llc Non-gelatin soft capsule system
US20070053868A1 (en) 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents

Also Published As

Publication number Publication date
US10022344B2 (en) 2018-07-17
EP1863458A1 (en) 2007-12-12
CA2600023A1 (en) 2006-09-14
EP1863458B2 (en) 2022-03-02
CY1118321T1 (el) 2017-06-28
US20070053868A1 (en) 2007-03-08
CN102940887A (zh) 2013-02-27
US10028925B2 (en) 2018-07-24
SI1863458T2 (sl) 2022-05-31
US20170296495A1 (en) 2017-10-19
US20160263063A1 (en) 2016-09-15
EP1863458B1 (en) 2016-09-14
MX2007011039A (es) 2008-03-07
WO2006096580A1 (en) 2006-09-14
SI1863458T1 (sl) 2017-01-31
PL1863458T3 (pl) 2017-03-31
ES2606767T5 (es) 2022-05-06
CA2600023C (en) 2011-11-01
US20210338616A1 (en) 2021-11-04
LT1863458T (lt) 2016-12-12
US20180071236A1 (en) 2018-03-15
CN102940887B (zh) 2015-12-23
US9693979B2 (en) 2017-07-04
DK1863458T4 (da) 2022-04-04
CN101166520A (zh) 2008-04-23
DK1863458T3 (da) 2017-01-02
US20180296512A1 (en) 2018-10-18
CN101166520B (zh) 2013-01-09
EP3061447A1 (en) 2016-08-31
HUE030784T2 (en) 2017-06-28
US9693978B2 (en) 2017-07-04
US20160106841A1 (en) 2016-04-21
US11090280B2 (en) 2021-08-17
ES2606767T3 (es) 2017-03-27
PL1863458T5 (pl) 2023-01-02
US20240342123A1 (en) 2024-10-17

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