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PT1682493E - Derivados de aminoacetonitrilo - Google Patents

Derivados de aminoacetonitrilo Download PDF

Info

Publication number
PT1682493E
PT1682493E PT04797665T PT04797665T PT1682493E PT 1682493 E PT1682493 E PT 1682493E PT 04797665 T PT04797665 T PT 04797665T PT 04797665 T PT04797665 T PT 04797665T PT 1682493 E PT1682493 E PT 1682493E
Authority
PT
Portugal
Prior art keywords
amidoacetonitrile derivatives
amidoacetonitrile
derivatives
Prior art date
Application number
PT04797665T
Other languages
English (en)
Inventor
Thomas Goebel
Pierre Ducray
Noelle Gauvry
Francois Pautrat
Ronald Kaminsky
Martin Jung
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1682493E publication Critical patent/PT1682493E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT04797665T 2003-11-06 2004-11-05 Derivados de aminoacetonitrilo PT1682493E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025290 2003-11-06
GBGB0402677.9A GB0402677D0 (en) 2003-11-06 2004-02-06 Organic compounds

Publications (1)

Publication Number Publication Date
PT1682493E true PT1682493E (pt) 2009-02-12

Family

ID=34575667

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04797665T PT1682493E (pt) 2003-11-06 2004-11-05 Derivados de aminoacetonitrilo

Country Status (22)

Country Link
US (2) US7494956B2 (pt)
EP (1) EP1682493B8 (pt)
JP (1) JP4319680B2 (pt)
KR (1) KR100793462B1 (pt)
CN (1) CN100447130C (pt)
AR (1) AR046322A1 (pt)
AT (1) ATE420066T1 (pt)
AU (1) AU2004287611B2 (pt)
BR (1) BRPI0416294B1 (pt)
CA (1) CA2544741C (pt)
DE (1) DE602004018967D1 (pt)
DK (1) DK1682493T3 (pt)
ES (1) ES2317070T3 (pt)
GB (1) GB0402677D0 (pt)
MX (1) MXPA06005036A (pt)
NZ (1) NZ546830A (pt)
PL (1) PL1682493T3 (pt)
PT (1) PT1682493E (pt)
RU (1) RU2370485C2 (pt)
SI (1) SI1682493T1 (pt)
TW (1) TWI342875B (pt)
WO (1) WO2005044784A1 (pt)

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GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
CN102558082B (zh) 2004-03-05 2015-09-30 日产化学工业株式会社 异噁唑啉取代苯甲酰胺化合物的制备中间体
BRPI0517970B1 (pt) * 2004-11-09 2017-01-31 Novartis Ag processo para a preparação de enanciômeros de compostos de amidoacetonitrila a partir de seus racematos
PT2118055E (pt) * 2007-02-09 2013-11-19 Zoetis Uk Ltd Agentes antiparasitários
SI2118055T1 (sl) * 2007-02-09 2013-12-31 Zoetis Uk Limited Antiparazitska sredstva
CA2678149C (en) 2007-02-21 2013-04-16 Pfizer Limited Benzofuran antiparasitic agents
DK2155699T5 (en) 2007-05-15 2017-05-22 Merial Inc ARYLAZOL-2-YL-CYANOETHYLAMINO COMPOUNDS, METHOD OF PREPARATION AND PROCEDURE FOR USING THEREOF
JP5413855B2 (ja) 2007-06-07 2014-02-12 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 外寄生生物の制御
KR101769728B1 (ko) 2007-06-27 2017-08-18 이 아이 듀폰 디 네모아 앤드 캄파니 동물 해충 방제 방법
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
NZ592382A (en) 2008-10-21 2013-03-28 Merial Ltd Thioamide compounds, method of making and method of using thereof
MX2011005011A (es) 2008-11-14 2011-07-29 Merial Ltd Compuestos de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, metodo de elaboracion y de uso de los mismos.
AU2009324074B2 (en) * 2008-12-03 2014-10-23 Elanco Tiergesundheit Ag Amidoacetonitrile compounds and pesticidal composition thereof
GB0905365D0 (en) * 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
US8962681B2 (en) 2011-10-19 2015-02-24 Zoetis Llc Use of aminoacetonitrile derivatives against endoparasites
JP6165231B2 (ja) * 2012-03-23 2017-07-19 ピットニー・ファーマシューティカルズ・ピーティーワイ・リミテッド 癌の治療のためのキナーゼ阻害剤
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
CN103030575B (zh) * 2013-01-04 2014-10-01 中国农业大学 一类双氰基酰胺化合物及其合成方法与应用
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
MX2016000055A (es) * 2013-07-01 2016-08-18 Univ Zuerich Derivados de n-(1-ciano-2-hidroxi-1-metil-etil)-4-(trifluorometils ulfanil)benzamida para su uso como farmacos nematicidas.
EP2821412A1 (en) 2013-07-01 2015-01-07 Universität Zürich Organometallic 2-cyano-2-aminobenzoate-propyl derivates and their use as anthelmintics
EP3043791B1 (en) 2013-09-13 2019-04-24 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
MX2016003804A (es) * 2013-09-26 2017-01-05 Univ Zuerich N-2-ciano-1-hidroxipropan-2-ilo organometalico para usar como antihelmintico.
JP2016537306A (ja) * 2013-09-26 2016-12-01 ウニヴェルズィテート チューリッヒ 駆虫薬として使用するための有機金属化合物
JP2016533336A (ja) 2013-09-26 2016-10-27 ウニヴェルズィテート チューリッヒ 駆虫薬として使用するためのビス−有機金属２−アミノ−３−ヒドロキシ−２−メチルプロパンニトリル誘導体
AU2014344789B2 (en) * 2013-11-01 2019-10-03 Pitney Pharmaceuticals Pty Limited Pharmaceutical combinations for the treatment of cancer
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
JP7697690B2 (ja) * 2020-03-04 2025-06-24 国立大学法人山口大学 新規なフルオロアルカン誘導体及びそれらを用いたゲル化剤

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ES2281453T3 (es) * 2000-12-20 2007-10-01 Novartis Ag Amidoacetonitrilos antiendoparasitarios.
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
US7705044B2 (en) * 2001-05-15 2010-04-27 Novartis Ag Benzamidoacetonitriles and their use as antiparasitics
TWI236341B (en) * 2001-06-15 2005-07-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
WO2003004474A1 (en) 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
MXPA04003157A (es) * 2001-10-04 2006-04-27 Novartis Ag Compuestos organicos.
NZ531640A (en) * 2001-10-04 2006-11-30 Novartis Ag Carbonyloxy-cyanomethyl compounds as antiparasitic agents for controlling parasites on warm-blooded animals
TW200300140A (en) * 2001-11-14 2003-05-16 Novartis Ag Organic compounds
AR037746A1 (es) * 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica
AR040082A1 (es) 2002-05-22 2005-03-16 Novartis Ag Derivados de n-acilaminoacetonitrilo y su uso para el control de parasitos
TW200400931A (en) * 2002-05-22 2004-01-16 Novartis Ag Organic compounds
AR039961A1 (es) * 2002-06-06 2005-03-09 Novartis Ag Derivados de amidoacetonitrilo y su uso como pesticida
TW200406386A (en) * 2002-06-07 2004-05-01 Novartis Ag Organic compounds
GB0214117D0 (en) * 2002-06-19 2002-07-31 Syngenta Participations Ag N-sulphonylaminoacetonitriles having pesticidal properties
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
AR042420A1 (es) * 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) * 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas
AR049391A1 (es) * 2004-06-10 2006-07-26 Novartis Ag Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente
BRPI0517970B1 (pt) 2004-11-09 2017-01-31 Novartis Ag processo para a preparação de enanciômeros de compostos de amidoacetonitrila a partir de seus racematos

Also Published As

Publication number Publication date
DK1682493T3 (da) 2009-04-20
RU2370485C2 (ru) 2009-10-20
ATE420066T1 (de) 2009-01-15
CN100447130C (zh) 2008-12-31
BRPI0416294B1 (pt) 2018-06-05
AU2004287611A1 (en) 2005-05-19
SI1682493T1 (sl) 2009-06-30
EP1682493A1 (en) 2006-07-26
US20070072944A1 (en) 2007-03-29
WO2005044784A1 (en) 2005-05-19
KR100793462B1 (ko) 2008-01-14
BRPI0416294A (pt) 2007-01-23
RU2006119506A (ru) 2007-12-27
GB0402677D0 (en) 2004-03-10
CA2544741A1 (en) 2005-05-19
JP2007510632A (ja) 2007-04-26
TWI342875B (en) 2011-06-01
EP1682493B1 (en) 2009-01-07
CA2544741C (en) 2012-08-07
PL1682493T3 (pl) 2009-06-30
AR046322A1 (es) 2005-11-30
MXPA06005036A (es) 2006-07-06
US20090176868A1 (en) 2009-07-09
TW200528024A (en) 2005-09-01
ES2317070T3 (es) 2009-04-16
US7964635B2 (en) 2011-06-21
KR20060088122A (ko) 2006-08-03
AU2004287611B2 (en) 2008-05-15
US7494956B2 (en) 2009-02-24
DE602004018967D1 (de) 2009-02-26
JP4319680B2 (ja) 2009-08-26
NZ546830A (en) 2009-07-31
EP1682493B8 (en) 2009-11-25
CN1902162A (zh) 2007-01-24

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