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PT1578439E - Métodos de dose baixa para tratamento de distúrbios nos quais a actividade de tnfα é nociva - Google Patents

Métodos de dose baixa para tratamento de distúrbios nos quais a actividade de tnfα é nociva Download PDF

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Publication number
PT1578439E
PT1578439E PT03809644T PT03809644T PT1578439E PT 1578439 E PT1578439 E PT 1578439E PT 03809644 T PT03809644 T PT 03809644T PT 03809644 T PT03809644 T PT 03809644T PT 1578439 E PT1578439 E PT 1578439E
Authority
PT
Portugal
Prior art keywords
tnf
detrimental
low dose
treating disorders
alpha activity
Prior art date
Application number
PT03809644T
Other languages
English (en)
Inventor
Zehra Kaymakcalan
Robert Kamen
Original Assignee
Abbott Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Biotech Ltd filed Critical Abbott Biotech Ltd
Publication of PT1578439E publication Critical patent/PT1578439E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Diabetes (AREA)
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  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
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  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
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  • Biophysics (AREA)
  • Obesity (AREA)
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PT03809644T 2002-10-24 2003-10-24 Métodos de dose baixa para tratamento de distúrbios nos quais a actividade de tnfα é nociva PT1578439E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42126202P 2002-10-24 2002-10-24

Publications (1)

Publication Number Publication Date
PT1578439E true PT1578439E (pt) 2011-10-19

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PT03809644T PT1578439E (pt) 2002-10-24 2003-10-24 Métodos de dose baixa para tratamento de distúrbios nos quais a actividade de tnfα é nociva

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US (2) US8846046B2 (pt)
EP (3) EP2332565A1 (pt)
JP (3) JP5594803B2 (pt)
KR (4) KR20050083805A (pt)
CN (2) CN103623408A (pt)
AR (2) AR045710A1 (pt)
AT (1) ATE517632T1 (pt)
AU (2) AU2003301522B8 (pt)
BR (1) BR0315597A (pt)
CA (1) CA2497909A1 (pt)
DK (1) DK1578439T3 (pt)
ES (1) ES2370351T3 (pt)
MX (1) MXPA05004344A (pt)
MY (1) MY150740A (pt)
NZ (3) NZ596945A (pt)
PE (1) PE20040751A1 (pt)
PL (2) PL213215B1 (pt)
PT (1) PT1578439E (pt)
SA (1) SA04240497A (pt)
SI (1) SI1578439T1 (pt)
TW (3) TWI423817B (pt)
UY (1) UY28041A1 (pt)
WO (1) WO2004037205A2 (pt)
ZA (1) ZA200502983B (pt)

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US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
US20040009172A1 (en) * 2002-04-26 2004-01-15 Steven Fischkoff Use of anti-TNFalpha antibodies and another drug
BR0312785A (pt) * 2002-07-19 2005-08-30 Abbott Biotech Ltd Tratamento de desordens relacionadas a tnf(alfa)
US20090280065A1 (en) * 2006-04-10 2009-11-12 Willian Mary K Uses and Compositions for Treatment of Psoriasis
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
MY150740A (en) 2002-10-24 2014-02-28 Abbvie Biotechnology Ltd Low dose methods for treating disorders in which tnf? activity is detrimental
BRPI0414313A (pt) * 2003-09-11 2006-11-07 Kemia Inc inibidores de citocinas
TWI556829B (zh) 2004-04-09 2016-11-11 艾伯維生物技術有限責任公司 用於治療ＴＮＦα相關失調症之多重可變劑量療法
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
EP1807111A4 (en) * 2004-10-08 2009-05-27 Abbott Biotech Ltd SYNCYTIAL RESPIRATORY VIRUS INFECTION (RSV)
MX2007014440A (es) 2005-05-16 2008-02-11 Abbott Biotech Ltd Uso de inhibidor de tnf para tratamiento de poliartritis erosiva.
US20070041905A1 (en) * 2005-08-19 2007-02-22 Hoffman Rebecca S Method of treating depression using a TNF-alpha antibody
HRP20131112T1 (hr) * 2005-11-01 2014-01-03 Abbvie Biotechnology Ltd Postupak za odreä�ivanje uäśinkovitosti adalimumaba kod subjekata koji pate od ankilozantnog spondilitisa pomoä†u ctx-ii i mmp3 kao biomarkera
WO2007058990A2 (en) * 2005-11-14 2007-05-24 Kemia, Inc. Therapy using cytokine inhibitors
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US9889156B2 (en) 2006-01-19 2018-02-13 The Regents Of The University Of Michigan Method for treating noise-induced hearing loss (NIHL)
US7951845B2 (en) 2006-01-19 2011-05-31 The Regents Of The University Of Michigan Composition and method of treating hearing loss
US10238599B2 (en) 2006-01-19 2019-03-26 The Regents Of The University Of Michigan Composition and method for treating congenital cytomegalovirus induced hearing loss
US8927528B2 (en) 2006-01-19 2015-01-06 The Regents Of The University Of Michigan Composition for treating hearing loss
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ATE517632T1 (de) 2011-08-15
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EP1578439B1 (en) 2011-07-27
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