PT1200561E - Clone celular recombinante estavel, sua producao e utilizacao - Google Patents
Clone celular recombinante estavel, sua producao e utilizacaoInfo
- Publication number
- PT1200561E PT1200561E PT99939251T PT99939251T PT1200561E PT 1200561 E PT1200561 E PT 1200561E PT 99939251 T PT99939251 T PT 99939251T PT 99939251 T PT99939251 T PT 99939251T PT 1200561 E PT1200561 E PT 1200561E
- Authority
- PT
- Portugal
- Prior art keywords
- production
- stabile
- proteins
- utilization
- serum
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 4
- 230000001413 cellular effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 3
- 239000002028 Biomass Substances 0.000 abstract 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/AT1999/000197 WO2001011021A1 (de) | 1999-08-05 | 1999-08-05 | Rekombinanter stabiler zellklon, seine herstellung und verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1200561E true PT1200561E (pt) | 2006-09-29 |
Family
ID=3683861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99939251T PT1200561E (pt) | 1999-08-05 | 1999-08-05 | Clone celular recombinante estavel, sua producao e utilizacao |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1200561B1 (pt) |
| JP (1) | JP2003506077A (pt) |
| AT (1) | ATE330003T1 (pt) |
| AU (1) | AU780810B2 (pt) |
| CA (1) | CA2381173A1 (pt) |
| CY (1) | CY1106111T1 (pt) |
| DE (1) | DE59913565D1 (pt) |
| DK (1) | DK1200561T3 (pt) |
| ES (1) | ES2267280T3 (pt) |
| PT (1) | PT1200561E (pt) |
| WO (1) | WO2001011021A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4330597A (en) | 1996-08-30 | 1998-03-19 | Life Technologies, Inc. | Serum-free mammalian cell culture medium, and uses thereof |
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| EP1325127B1 (en) * | 2000-10-02 | 2009-03-11 | Novo Nordisk Health Care AG | Method for the production of vitamin k-dependent proteins |
| WO2003029442A1 (en) | 2001-10-02 | 2003-04-10 | Novo Nordisk Health Care Ag | Method for production of recombinant proteins in eukaryote cells |
| IL161858A0 (en) * | 2001-11-28 | 2005-11-20 | Sandoz Ag | Cell culture process |
| AU2002354363A1 (en) * | 2001-12-04 | 2003-06-17 | Mitsubishi Pharma Corporation | Method of activating protein |
| PT2287288E (pt) | 2002-07-09 | 2012-12-10 | Baxter Int | Meio isento de proteína animal para cultura de células |
| DE10338531A1 (de) * | 2003-08-19 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Reklonierung von Produktionszellen |
| US8669109B2 (en) | 2003-08-19 | 2014-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methods of producing proteins in Chinese hamster ovary (CHO) cells |
| CA2551916C (en) * | 2003-12-31 | 2014-04-29 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Fc-erythropoietin fusion protein with improved pharmacokinetics |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| AU2011221414B2 (en) * | 2004-10-29 | 2012-09-20 | Takeda Pharmaceutical Company Limited | Animal Protein-Free Media for Cultivation of Cells |
| EP1851305B1 (en) * | 2005-02-11 | 2012-01-18 | Novo Nordisk Health Care AG | Production of a polypeptide in a serum-free cell culture liquid containing plant protein hydrolysate |
| WO2007077217A2 (en) | 2006-01-04 | 2007-07-12 | Baxter International Inc. | Oligopeptide-free cell culture media |
| PL2356247T5 (pl) * | 2008-11-12 | 2019-10-31 | Baxalta Inc | Sposób wytwarzania czynnika VII wolnego od surowicy i wolnego od insuliny |
| CN119677836A (zh) * | 2022-07-27 | 2025-03-21 | 不二制油集团控股株式会社 | 动物细胞增殖促进剂 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9022545D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| DE4313620A1 (de) * | 1993-04-26 | 1994-10-27 | Biotechnolog Forschung Gmbh | Hamsterzellinien und Verfahren zur Glykoproteingewinnung |
| EP0666312A1 (en) * | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Process for the improvement of mammalian cell growth |
| EP1213030B1 (en) * | 1994-11-10 | 2009-04-22 | Baxter Healthcare SA | Method for producing biologicals in protein-free culture |
| EP0799310A1 (en) * | 1994-12-16 | 1997-10-08 | Novartis AG | Production of recombinant secretory component |
| AUPN442295A0 (en) * | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
| US5851800A (en) * | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
-
1999
- 1999-08-05 WO PCT/AT1999/000197 patent/WO2001011021A1/de not_active Ceased
- 1999-08-05 AT AT99939251T patent/ATE330003T1/de active
- 1999-08-05 AU AU53636/99A patent/AU780810B2/en not_active Expired
- 1999-08-05 CA CA 2381173 patent/CA2381173A1/en not_active Abandoned
- 1999-08-05 JP JP2001515808A patent/JP2003506077A/ja not_active Withdrawn
- 1999-08-05 PT PT99939251T patent/PT1200561E/pt unknown
- 1999-08-05 EP EP99939251A patent/EP1200561B1/de not_active Revoked
- 1999-08-05 ES ES99939251T patent/ES2267280T3/es not_active Expired - Lifetime
- 1999-08-05 DE DE59913565T patent/DE59913565D1/de not_active Expired - Lifetime
- 1999-08-05 DK DK99939251T patent/DK1200561T3/da active
-
2006
- 2006-07-03 CY CY20061100911T patent/CY1106111T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU780810B2 (en) | 2005-04-21 |
| ATE330003T1 (de) | 2006-07-15 |
| CY1106111T1 (el) | 2011-06-08 |
| CA2381173A1 (en) | 2001-02-15 |
| DE59913565D1 (de) | 2006-07-27 |
| JP2003506077A (ja) | 2003-02-18 |
| DK1200561T3 (da) | 2006-10-16 |
| EP1200561B1 (de) | 2006-06-14 |
| ES2267280T3 (es) | 2007-03-01 |
| AU5363699A (en) | 2001-03-05 |
| EP1200561A1 (de) | 2002-05-02 |
| WO2001011021A1 (de) | 2001-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1200561E (pt) | Clone celular recombinante estavel, sua producao e utilizacao | |
| ATE331025T2 (de) | Medium für die protein- und serumfreie zellkultur | |
| CA2095852A1 (en) | Proteins with changed epitopes and methods for the production thereof | |
| DE3580654D1 (de) | Menschlicher hybridomfusionspartner zur herstellung menschlicher monoklonaler antikoerper. | |
| DE69332981D1 (de) | Methoden zur herstellung löslicher, oligomerer proteine | |
| DE60144145D1 (de) | Subtilisin-variante | |
| HUP0101136A2 (hu) | Fehérjeexpresszió baculovírus-vektort alkalmazó expressziós rendszerben | |
| AR018023A1 (es) | Procedimiento para la fabricacion de polipeptidos con glicosilacion apropiada | |
| ATE153214T1 (de) | Medien zur zellzucht und verfahren dazu | |
| ATE197068T1 (de) | Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung | |
| DE69132902D1 (de) | Methoden zur identifizierung heterofunktionaler fusionsproteine | |
| DE69939548D1 (de) | Verfahren zur herstellung von faktor vii | |
| ATE309267T1 (de) | Methode zur proliferation und differenzierung von b-zellen und verwendungen dafür | |
| WO2002030958A3 (de) | Casein-peptidfragmente mit wachstumsbeeinflussender aktivität auf zellkulturen | |
| ATE407941T1 (de) | Mit einer kohlenhydratgruppe chemisch modifizierte proteine | |
| DE69529674D1 (de) | Biologisch aktive ligande der eph familie | |
| DE60226896D1 (de) | Herstellung von f(ab')2 fragmenten in saügetierzelle | |
| DK0939769T3 (da) | Vertebrat-Smoothened-proteiner | |
| ES2168282T3 (es) | D-hidantoinasa recombinante, procedimiento para su preparacion y utilizacion. | |
| DE69934250D1 (de) | Zusammensetzungen und verfahren zur herstellung monoklonaler antikörper, repräsentativ für einen spezifischen zelltyp | |
| KR890005272A (ko) | 흉선 간질-유래 t세포 성장인자 및 그의 제조방법 | |
| DE69425809D1 (de) | Methoden zur Herstellung von Protein C | |
| ATE103989T1 (de) | Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung. | |
| ATE72458T1 (de) | Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen. | |
| DE60042273D1 (de) | Antitumorantikörper, proteine und deren verwendung |