PT1117296E - Combinacao de bisfosfonato e de tetraciclina - Google Patents
Combinacao de bisfosfonato e de tetraciclinaInfo
- Publication number
- PT1117296E PT1117296E PT99948446T PT99948446T PT1117296E PT 1117296 E PT1117296 E PT 1117296E PT 99948446 T PT99948446 T PT 99948446T PT 99948446 T PT99948446 T PT 99948446T PT 1117296 E PT1117296 E PT 1117296E
- Authority
- PT
- Portugal
- Prior art keywords
- bisphosphonate
- tetracycline
- combination
- proteinase
- synergistic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/161,804 US5998390A (en) | 1998-09-28 | 1998-09-28 | Combination of bisphosphonate and tetracycline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1117296E true PT1117296E (pt) | 2005-08-31 |
Family
ID=22582811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99948446T PT1117296E (pt) | 1998-09-28 | 1999-09-24 | Combinacao de bisfosfonato e de tetraciclina |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5998390A (pt) |
| EP (1) | EP1117296B1 (pt) |
| JP (1) | JP2002525294A (pt) |
| KR (1) | KR20010075220A (pt) |
| AT (1) | ATE290782T1 (pt) |
| AU (1) | AU755871B2 (pt) |
| CA (1) | CA2343098A1 (pt) |
| DE (1) | DE69924268T2 (pt) |
| ES (1) | ES2237945T3 (pt) |
| PT (1) | PT1117296E (pt) |
| WO (1) | WO2000018230A1 (pt) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331533B1 (en) | 1998-11-16 | 2001-12-18 | Merck & Co., Inc. | Method for inhibiting dental resorptive lesions |
| US6946453B2 (en) | 1998-11-18 | 2005-09-20 | Collagenex Pharmaceuticals, Inc. | 4-dedimethylaminotracycline derivatives |
| US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| ATE253368T1 (de) * | 1998-12-23 | 2003-11-15 | Bioagency Ag | Verwendung von bisphosphonaten zur prophylaxe und zur behandlung von infektiösen prozessen |
| US6506733B1 (en) * | 1999-03-15 | 2003-01-14 | Axys Pharmaceuticals, Inc. | Compounds and compositions as protease inhibitors |
| GB9907908D0 (en) * | 1999-04-07 | 1999-06-02 | Bataille Regis | Organic compounds |
| US7268148B2 (en) * | 1999-05-20 | 2007-09-11 | Regents Of The University Of Michigan | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes |
| EP1114642B1 (en) * | 1999-07-19 | 2010-01-06 | Toray Industries, Inc. | Drugs for periodontal diseases |
| JP4074043B2 (ja) * | 2000-03-27 | 2008-04-09 | 株式会社資生堂 | 皮膚基底膜形成促進剤、人工皮膚形成促進剤及び人工皮膚の製造方法 |
| US20020132798A1 (en) | 2000-06-16 | 2002-09-19 | Nelson Mark L. | 7-phenyl-substituted tetracycline compounds |
| US20060040899A1 (en) * | 2000-12-15 | 2006-02-23 | Hassan Jomaa | Medicaments containing bisphosphonic acids and derivatives thereof for preventing and treating diseases and allergies |
| WO2002051983A2 (en) | 2000-12-22 | 2002-07-04 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions as cathepsin inhibitors |
| US7030116B2 (en) * | 2000-12-22 | 2006-04-18 | Aventis Pharmaceuticals Inc. | Compounds and compositions as cathepsin inhibitors |
| EP1383483A4 (en) * | 2001-04-05 | 2006-08-09 | Collagenex Pharm Inc | CONTROLLED RELEASE OF TETRACYCLIN COMPOUNDS AND TETRACYCLINE DERIVATIVES |
| US7211267B2 (en) * | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
| EP1716856A3 (en) * | 2001-04-05 | 2009-02-18 | Collagenex Pharmaceuticals, Inc. | The treatment of acne |
| CA2372450A1 (en) * | 2001-05-10 | 2001-09-19 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| EA007335B1 (ru) * | 2001-06-01 | 2006-08-25 | Эксис Фармасьютикалз, Инк. | Новые соединения и композиции как ингибиторы катепсина |
| US20040147503A1 (en) * | 2002-06-04 | 2004-07-29 | Sheila Zipfeil | Novel compounds and compositions as cathepsin inhibitors |
| US20040063674A1 (en) | 2001-07-13 | 2004-04-01 | Levy Stuart B. | Tetracycline compounds having target therapeutic activities |
| US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
| KR20040044920A (ko) * | 2001-09-14 | 2004-05-31 | 아벤티스 파마슈티칼스 인크. | 카뎁신 억제제로서 신규한 화합물 및 조성물 |
| CA2467391A1 (en) * | 2001-11-14 | 2003-05-22 | Aventis Pharmaceuticals Inc. | Oligopeptides and compositions containing them as cathepsin s inhibitors |
| AU2003235759A1 (en) | 2002-01-08 | 2003-07-24 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
| AU2003214876B2 (en) | 2002-01-23 | 2008-06-12 | Dentsply International Inc. | Irrigation solution and methods for use |
| EP1482926A4 (en) | 2002-03-08 | 2006-04-12 | Paratek Pharm Innc | AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS |
| KR101083498B1 (ko) | 2002-03-21 | 2011-11-16 | 파라테크 파마슈티컬스, 인크. | 치환된 테트라시클린 화합물 |
| EP1501490A2 (en) * | 2002-05-06 | 2005-02-02 | Collagenex Pharmaceuticals, Inc. | Methods of simultaneously treating mucositis and fungal infection |
| EP1505961A4 (en) * | 2002-05-20 | 2009-09-02 | Collagenex Pharm Inc | METHOD FOR TREATING ALLERGIC REACTIONS |
| CA2492273C (en) | 2002-07-12 | 2013-02-05 | Paratek Pharmaceuticals, Inc. | 3, 10, and 12a substituted tetracycline compounds |
| PT2204168E (pt) | 2003-04-07 | 2015-03-05 | Supernus Pharmaceuticals Inc | Formulações de tetraciclinas de dose única diária |
| US20070025960A1 (en) * | 2003-05-16 | 2007-02-01 | University Of Maryland Biotechnology Institute | Bisphosphonates for prophylaxis and therapy against bioterrorism agents |
| JP4463274B2 (ja) * | 2003-06-27 | 2010-05-19 | 明 小谷 | ビスホスホネート錯体 |
| WO2005009944A1 (en) | 2003-07-09 | 2005-02-03 | Paratek Pharmaceuticals, Inc. | Prodrugs of 9-aminomethyl tetracycline compounds |
| EP2319828A3 (en) | 2003-07-09 | 2011-07-06 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| MXPA06000790A (es) * | 2003-07-21 | 2006-04-07 | Novartis Ag | Combinaciones de un inhibidor de catepsina k y un bisfofonato en el tratamiento de metastasis osea, crecimiento de tumor y perdida osea inducida por tumor. |
| US7786099B2 (en) * | 2004-01-15 | 2010-08-31 | Paratek Pharmaceuticals, Inc. | Aromatic a-ring derivatives of tetracycline compounds |
| US20050220760A1 (en) * | 2004-04-02 | 2005-10-06 | Clemson University | Novel immunotherapy |
| JP2008518025A (ja) | 2004-10-25 | 2008-05-29 | パラテック ファーマシューティカルズ インコーポレイテッド | 4−アミノテトラサイクリンおよびその使用の方法 |
| AU2005299569B2 (en) | 2004-10-25 | 2012-06-07 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| US20060112494A1 (en) * | 2004-12-01 | 2006-06-01 | David Oppong | Method of protecting an animal skin product from metalloproteinase activity |
| US20060134190A1 (en) * | 2004-12-16 | 2006-06-22 | Banner Pharmacaps Inc. | Formulations of bisphosphonate drugs with improved bioavailability |
| US20060252731A1 (en) * | 2005-05-06 | 2006-11-09 | Pfeiffer David F | Methods of treating recurrent aphthous stomatitis |
| DE202006006920U1 (de) * | 2006-04-25 | 2007-08-30 | Biomed Est. | Dentalimplantat |
| KR20080080205A (ko) * | 2005-12-22 | 2008-09-02 | 와이어쓰 | 티게사이클린을 포함하는 경구 제형 |
| CA2631632A1 (en) * | 2005-12-22 | 2007-07-05 | Wyeth | Methods of treating gastrointestinal tract infections with tigecycline |
| US20070264613A1 (en) * | 2006-03-07 | 2007-11-15 | Biomed Est. | Dental implant |
| DK2120963T3 (en) * | 2006-12-21 | 2019-01-14 | Paratek Pharm Innc | SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY SKIN DISORDERS |
| EP2452935A3 (en) | 2006-12-21 | 2012-08-29 | Paratek Pharmaceuticals, Inc. | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections |
| EP2213655A1 (en) * | 2007-04-27 | 2010-08-04 | Paratek Pharmaceuticals, Inc. | Methods For Purifying Aminoalkyl Tetracycline Compounds |
| BRPI0823405A2 (pt) * | 2007-07-06 | 2012-12-25 | Paratek Pharmaceuticals, Inc. | mÉtodos para sintetizar compostos de tetraciclina substituÍda |
| KR20100045450A (ko) * | 2007-08-02 | 2010-05-03 | 데이진 화-마 가부시키가이샤 | 골 대사 이상에서 기인하는 질환의 예방제 또는 치료제 |
| TW202021946A (zh) | 2008-05-19 | 2020-06-16 | 美商派洛泰克藥物股份有限公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| KR20100014090A (ko) * | 2008-08-01 | 2010-02-10 | 동화약품주식회사 | 벤즈아미딘 유도체 또는 이의 염, 및 비스포스포네이트를 포함하는 골다공증의 예방 또는 치료용 약학 조성물 |
| WO2010013969A2 (en) * | 2008-08-01 | 2010-02-04 | Dong Wha Pharmaceutical Co., Ltd. | A pharmaceutical composition for preventing or treating osteoporosis comprising benzamidine derivatives or their salts, and alendronic acid or its salt |
| MX358961B (es) | 2008-08-08 | 2018-09-10 | Tetraphase Pharmaceuticals Inc Star | Compuestos de tetraciclina sustituidos con fluor en c7. |
| ES2627772T3 (es) | 2009-05-08 | 2017-07-31 | Tetraphase Pharmaceuticals, Inc. | Compuestos de tetraciclina |
| CN105622496B (zh) | 2009-08-28 | 2019-03-05 | 四相制药公司 | 四环素类化合物 |
| EP2552890B1 (en) | 2010-03-31 | 2017-01-04 | Tetraphase Pharmaceuticals, Inc. | Polycyclic tetracycline compounds |
| SG10201801703RA (en) | 2012-08-31 | 2018-04-27 | Tetraphase Pharmaceuticals Inc | Tetracycline compounds |
| EP3220899A1 (en) | 2014-11-19 | 2017-09-27 | Nestlé Skin Health SA | Modified release doxycycline composition |
| MA46567A (fr) | 2016-10-19 | 2019-08-28 | Tetraphase Pharmaceuticals Inc | Formes cristallines de l'éravacycline |
| WO2020097450A1 (en) | 2018-11-09 | 2020-05-14 | Tetraphase Pharmaceuticals, Inc. | Polymorphic forms of a compound and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34656A (en) * | 1862-03-11 | Improvement in liquids for exciting galvanic batteries | ||
| USRE34656E (en) | 1983-12-29 | 1994-07-05 | The Research Foundation Of State University Of New York | Use of tetracycline to enhance bone protein synthesis and/or treatment of bone deficiency |
| US4935412A (en) * | 1983-12-29 | 1990-06-19 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
| US4666897A (en) * | 1983-12-29 | 1987-05-19 | Research Foundation Of State University | Inhibition of mammalian collagenolytic enzymes by tetracyclines |
| US4704383A (en) * | 1983-12-29 | 1987-11-03 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
| JP3016587B2 (ja) * | 1989-12-04 | 2000-03-06 | ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク | 非ステロイド抗炎症剤及びテトラサイクリンの配合 |
| US5308839A (en) * | 1989-12-04 | 1994-05-03 | The Research Foundation Of State University Of New York | Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline |
| FI89365C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
| US5258371A (en) * | 1992-05-29 | 1993-11-02 | Kuraray Co., Ltd. | Method to reduce connective tissue destruction |
| US5403829A (en) * | 1993-03-24 | 1995-04-04 | Leiras Oy | Use of bisphosphonates in endo-osteal bone surgery |
| WO1995028145A1 (en) * | 1994-04-18 | 1995-10-26 | The Procter & Gamble Company | Iontophoretic delivery of bisphosphonates to the alveolar bone |
| US5652227A (en) * | 1995-01-30 | 1997-07-29 | Teronen; Olli Pekka | Inhibition of the degradation of connective tissue matrix protein components in mammals |
| US5880111A (en) * | 1995-06-07 | 1999-03-09 | Farcasiu; Dan | Therapeutic derivations of diphosphonates |
| US5773430A (en) * | 1997-03-13 | 1998-06-30 | Research Foundation Of State University Of New York | Serine proteinase inhibitory activity by hydrophobic tetracycline |
-
1998
- 1998-09-28 US US09/161,804 patent/US5998390A/en not_active Expired - Lifetime
-
1999
- 1999-09-02 US US09/388,762 patent/US6114316A/en not_active Expired - Lifetime
- 1999-09-24 AT AT99948446T patent/ATE290782T1/de not_active IP Right Cessation
- 1999-09-24 PT PT99948446T patent/PT1117296E/pt unknown
- 1999-09-24 WO PCT/US1999/022199 patent/WO2000018230A1/en not_active Ceased
- 1999-09-24 ES ES99948446T patent/ES2237945T3/es not_active Expired - Lifetime
- 1999-09-24 EP EP99948446A patent/EP1117296B1/en not_active Expired - Lifetime
- 1999-09-24 CA CA002343098A patent/CA2343098A1/en not_active Abandoned
- 1999-09-24 AU AU61620/99A patent/AU755871B2/en not_active Ceased
- 1999-09-24 KR KR1020017003547A patent/KR20010075220A/ko not_active Abandoned
- 1999-09-24 DE DE69924268T patent/DE69924268T2/de not_active Expired - Fee Related
- 1999-09-24 JP JP2000571758A patent/JP2002525294A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002525294A (ja) | 2002-08-13 |
| AU6162099A (en) | 2000-04-17 |
| WO2000018230A1 (en) | 2000-04-06 |
| CA2343098A1 (en) | 2000-04-06 |
| ATE290782T1 (de) | 2005-04-15 |
| AU755871B2 (en) | 2003-01-02 |
| EP1117296A1 (en) | 2001-07-25 |
| US6114316A (en) | 2000-09-05 |
| KR20010075220A (ko) | 2001-08-09 |
| ES2237945T3 (es) | 2005-08-01 |
| DE69924268T2 (de) | 2006-02-09 |
| DE69924268D1 (de) | 2005-04-21 |
| US5998390A (en) | 1999-12-07 |
| EP1117296B1 (en) | 2005-03-16 |
| WO2000018230A9 (en) | 2000-10-26 |
| EP1117296A4 (en) | 2004-02-04 |
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