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PT1115701E - Ureias de arilsulfonanilida - Google Patents

Ureias de arilsulfonanilida

Info

Publication number
PT1115701E
PT1115701E PT99969408T PT99969408T PT1115701E PT 1115701 E PT1115701 E PT 1115701E PT 99969408 T PT99969408 T PT 99969408T PT 99969408 T PT99969408 T PT 99969408T PT 1115701 E PT1115701 E PT 1115701E
Authority
PT
Portugal
Prior art keywords
agents
arilsulfonanilida
urees
compositions
hypercholesterolemia
Prior art date
Application number
PT99969408T
Other languages
English (en)
Inventor
Jonathan B Houze
Original Assignee
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tularik Inc filed Critical Tularik Inc
Publication of PT1115701E publication Critical patent/PT1115701E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
PT99969408T 1998-09-23 1999-09-21 Ureias de arilsulfonanilida PT1115701E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10088898P 1998-09-23 1998-09-23

Publications (1)

Publication Number Publication Date
PT1115701E true PT1115701E (pt) 2003-09-30

Family

ID=22282047

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99969408T PT1115701E (pt) 1998-09-23 1999-09-21 Ureias de arilsulfonanilida

Country Status (23)

Country Link
US (3) US6214880B1 (pt)
EP (1) EP1115701B1 (pt)
JP (1) JP3926983B2 (pt)
KR (1) KR100642184B1 (pt)
CN (1) CN100335461C (pt)
AT (1) ATE240940T1 (pt)
AU (1) AU747663B2 (pt)
BR (1) BR9913903A (pt)
CA (1) CA2343204C (pt)
CZ (1) CZ2001934A3 (pt)
DE (1) DE69908156T2 (pt)
DK (1) DK1115701T3 (pt)
EA (1) EA003924B1 (pt)
ES (1) ES2194547T3 (pt)
HU (1) HUP0103884A3 (pt)
IL (2) IL142066A0 (pt)
NO (1) NO20011453L (pt)
NZ (1) NZ510435A (pt)
PL (1) PL198394B1 (pt)
PT (1) PT1115701E (pt)
SK (1) SK284757B6 (pt)
WO (1) WO2000017159A1 (pt)
ZA (1) ZA200102033B (pt)

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GB9508644D0 (en) * 1995-04-28 1995-06-14 Exxon Chemical Patents Inc Fuel compositions
CZ2001934A3 (cs) * 1998-09-23 2001-08-15 Tularik Inc. Arylsulfonanilidové močoviny
US6316503B1 (en) * 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
IL147890A0 (en) * 1999-07-29 2002-08-14 Tularik Inc Pharmaceutical compositions containing pentafluorobenzenesulfonamide derivatives
CO5280089A1 (es) * 2000-03-16 2003-05-30 Smithkline Beecham Corp Antagonistas del receptor il-8
US6664259B2 (en) 2000-03-16 2003-12-16 Smithkline Beecham Corporation Il-8 receptor antagonists
UY26627A1 (es) * 2000-03-24 2001-09-28 Smithkline Beecham Corp Antagonistas de receptores de il-8
WO2002020463A2 (en) * 2000-09-05 2002-03-14 Tularik Inc. Fxr modulators
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
WO2002039958A2 (en) 2000-11-03 2002-05-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
KR100850330B1 (ko) 2001-02-28 2008-08-04 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 N-(아릴)-2-아릴에텐술폰아미드 및 이를 이용한 약학적 조성물
AUPR738301A0 (en) * 2001-08-30 2001-09-20 Starpharma Limited Chemotherapeutic agents
ES2314212T3 (es) * 2002-01-30 2009-03-16 Amgen Inc. Compuestos arilsulfonamidobencilicos.
WO2003063796A2 (en) * 2002-01-30 2003-08-07 Tularik Inc. Heterocyclic arylsulfonamidobenzylic compounds
EP1534284B1 (en) 2002-02-28 2011-07-27 Temple University - Of The Commonwealth System of Higher Education Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
TW200418812A (en) * 2002-10-29 2004-10-01 Smithkline Beecham Corp IL-8 receptor antagonists
US20060264424A1 (en) * 2003-08-12 2006-11-23 Tularik Inc Arylsulfonamidobenzylic compounds
US20050124664A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Urea thiadiazole inhibitors of plasminogen activator inhibior-1
US20050154455A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
US20060062822A1 (en) * 2004-09-21 2006-03-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20070027530A1 (en) * 2005-07-26 2007-02-01 Medtronic Vascular, Inc. Intraluminal device, catheter assembly, and method of use thereof
FI20055498A0 (fi) * 2005-09-16 2005-09-16 Biotie Therapies Corp Sulfonamidijohdannaisia
US20070067020A1 (en) * 2005-09-22 2007-03-22 Medtronic Vasular, Inc. Intraluminal stent, delivery system, and a method of treating a vascular condition
WO2007124424A2 (en) * 2006-04-21 2007-11-01 Smithkline Beecham Corporation Il-8 receptor antagonists
JP2009534420A (ja) * 2006-04-21 2009-09-24 スミスクライン・ビーチャム・コーポレイション Il−8受容体アンタゴニスト
JP2009538317A (ja) * 2006-05-26 2009-11-05 バイエル ヘルスケア リミティド ライアビリティ カンパニー 癌治療のための置換ジアリールウレアを用いた薬物の組み合わせ
PE20080943A1 (es) * 2006-06-23 2008-09-27 Smithkline Beecham Corp Sal toluenosulfonato de 4-{[6-cloro-3-({[(2-cloro-3-fluorofenil)amino]carbonil}amino)-2-hidroxifenil]sulfonil}-1-piperazinacarboxilato de 1,1-dimetiletilo como antagonista del receptor de il-8
WO2009088549A2 (en) * 2007-10-19 2009-07-16 The Board Of Regents Of The University Of Texas System Methods of inhibiting bacterial virulence and compounds relating thereto
EP2385831A4 (en) * 2009-01-09 2014-03-26 Uab Research Foundation SMALL MOLECULAR HEMMER OF NADS, NAMNAT AND NMNAT
US9444712B2 (en) 2012-11-21 2016-09-13 Cisco Technology, Inc. Bandwidth on-demand services in multiple layer networks
JP5887423B2 (ja) * 2012-11-21 2016-03-16 日本曹達株式会社 非フェノール系化合物を用いた記録材料
WO2017170826A1 (ja) * 2016-03-30 2017-10-05 味の素株式会社 グルカゴン様ペプチド-1受容体作用増強活性を有する化合物

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US1955207A (en) 1931-09-16 1934-04-17 Ig Farbenindustrie Ag Mothproofing agent
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JP2001526255A (ja) 1997-12-23 2001-12-18 ワーナー−ランバート・カンパニー 炎症性疾患およびアテローム性動脈硬化症を治療または予防するチオ尿素およびベンズアミド化合物、組成物並びに方法
CZ2001934A3 (cs) * 1998-09-23 2001-08-15 Tularik Inc. Arylsulfonanilidové močoviny
IL147890A0 (en) * 1999-07-29 2002-08-14 Tularik Inc Pharmaceutical compositions containing pentafluorobenzenesulfonamide derivatives

Also Published As

Publication number Publication date
HUP0103884A2 (hu) 2002-05-29
EP1115701A1 (en) 2001-07-18
CZ2001934A3 (cs) 2001-08-15
CN1319088A (zh) 2001-10-24
SK284757B6 (sk) 2005-11-03
EP1115701B1 (en) 2003-05-21
ATE240940T1 (de) 2003-06-15
SK4002001A3 (en) 2001-09-11
ZA200102033B (en) 2001-09-12
DE69908156D1 (de) 2003-06-26
NZ510435A (en) 2003-04-29
BR9913903A (pt) 2001-07-03
CN100335461C (zh) 2007-09-05
IL142066A (en) 2006-07-05
AU747663B2 (en) 2002-05-16
CA2343204A1 (en) 2000-03-30
US7060718B2 (en) 2006-06-13
US6583165B2 (en) 2003-06-24
HUP0103884A3 (en) 2002-11-28
PL198394B1 (pl) 2008-06-30
US20030207864A1 (en) 2003-11-06
EA003924B1 (ru) 2003-10-30
KR20010079892A (ko) 2001-08-22
AU6058099A (en) 2000-04-10
DK1115701T3 (da) 2003-06-23
IL142066A0 (en) 2002-03-10
DE69908156T2 (de) 2003-12-24
US20010027211A1 (en) 2001-10-04
JP3926983B2 (ja) 2007-06-06
HK1038913A1 (en) 2002-04-04
US6214880B1 (en) 2001-04-10
KR100642184B1 (ko) 2006-11-10
NO20011453D0 (no) 2001-03-22
JP2002526472A (ja) 2002-08-20
ES2194547T3 (es) 2003-11-16
CA2343204C (en) 2008-04-29
NO20011453L (no) 2001-05-23
WO2000017159A1 (en) 2000-03-30
EA200100376A1 (ru) 2001-08-27
PL346797A1 (en) 2002-02-25

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