PL377106A1 - Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent - Google Patents
Depigmenting composition for the skin comprising adapalene and at least one depigmenting agentInfo
- Publication number
- PL377106A1 PL377106A1 PL377106A PL37710603A PL377106A1 PL 377106 A1 PL377106 A1 PL 377106A1 PL 377106 A PL377106 A PL 377106A PL 37710603 A PL37710603 A PL 37710603A PL 377106 A1 PL377106 A1 PL 377106A1
- Authority
- PL
- Poland
- Prior art keywords
- depigmenting
- adapalene
- skin
- composition
- agent
- Prior art date
Links
- LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002916 adapalene Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000007854 depigmenting agent Substances 0.000 title 1
- 206010008570 Chloasma Diseases 0.000 abstract 2
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 abstract 2
- 208000003351 Melanosis Diseases 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- NWVVVBRKAWDGAB-UHFFFAOYSA-N p-methoxyphenol Chemical compound COC1=CC=C(O)C=C1 NWVVVBRKAWDGAB-UHFFFAOYSA-N 0.000 abstract 1
- 230000000475 sunscreen effect Effects 0.000 abstract 1
- 239000000516 sunscreening agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Topically applicable skin depigmenting compositions, suited for treatment of such hyperpigmentary disorders as melasma and chloasma, contain a thus effective amount of at least one skin depigmenting active agent, for example hydroquinone or 4-hydroxyanisole, in admixture with a depigmentation-accelerating amount of adapalene (6-[3-(1-adamantyl)-4-methoxyphenyl]-2-napthanoic acid), and optionally with at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0211022 | 2002-09-05 | ||
| US41135002P | 2002-09-18 | 2002-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL377106A1 true PL377106A1 (en) | 2006-01-23 |
Family
ID=31979939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL377106A PL377106A1 (en) | 2002-09-05 | 2003-09-01 | Depigmenting composition for the skin comprising adapalene and at least one depigmenting agent |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20050163731A1 (en) |
| EP (1) | EP1536763B1 (en) |
| JP (1) | JP4662769B2 (en) |
| KR (1) | KR20050057238A (en) |
| CN (1) | CN100391432C (en) |
| AT (1) | ATE366566T1 (en) |
| AU (1) | AU2003270272B2 (en) |
| BR (1) | BR0313370B1 (en) |
| CA (1) | CA2495043A1 (en) |
| CY (1) | CY1107732T1 (en) |
| DE (1) | DE60314887T2 (en) |
| DK (1) | DK1536763T3 (en) |
| ES (1) | ES2289315T3 (en) |
| MX (1) | MXPA05002064A (en) |
| PL (1) | PL377106A1 (en) |
| PT (1) | PT1536763E (en) |
| RU (1) | RU2317066C2 (en) |
| WO (1) | WO2004021967A2 (en) |
| ZA (1) | ZA200501753B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7544674B2 (en) | 2002-10-25 | 2009-06-09 | Galderma S.A. | Topical skin care composition |
| PL374779A1 (en) * | 2002-12-12 | 2005-10-31 | Galderma Research & Development, S.N.C. | A water-alcohol discoloring gel containing a phenolic derivative and a retinoid |
| FR2871377B1 (en) * | 2004-06-11 | 2007-08-24 | Galderma Res & Dev | HYDRO-ALCOHOLIC DEPIGMENTING GEL COMPRISING MEQUINOL AND ADAPALENE |
| FR2890314B1 (en) * | 2005-09-02 | 2009-03-20 | Galderma Res & Dev | SKIN POWDER COMPOSITION COMPRISING ADAPALENE AT LEAST ONE DEPIGMENTING AGENT AND AT LEAST ONE ANTI-INFLAMMATORY AGENT |
| WO2007052157A2 (en) * | 2005-09-02 | 2007-05-10 | Galderma Research & Development | Depigmenting composition for the skin, comprising adapalene, at least one depigmenting agent and at least one anti-inflammatory agent |
| FR2894820B1 (en) * | 2005-12-15 | 2008-02-29 | Galderma Res & Dev | COMPOSITIONS COMPRISING AT LEAST ONE RETINOID COMPOUND AND AT LEAST ONE ANTI-IRRITANT COMPOUND AND USES THEREOF |
| FR2910321B1 (en) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | CREAM GEL COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE |
| FR2910320B1 (en) | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | EMULSION COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE |
| JP5646129B2 (en) * | 2007-03-31 | 2014-12-24 | 大正製薬株式会社 | Adapalene-containing external preparation composition |
| FR2915682B1 (en) * | 2007-05-04 | 2009-07-03 | Galderma Res & Dev | DERMATOLOGICAL AND COSMETIC DEPIGMENTING COMPOSITIONS, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF |
| US9364424B2 (en) * | 2007-11-19 | 2016-06-14 | Stiefel Laboratories, Inc. | Topical cosmetic skin lightening compositions and methods of use thereof |
| FR2931663B1 (en) * | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | NOVEL ANHYDROUS DEPIGMENTING COMPOSITIONS COMPRISING A SOLUBILIZED PHENOLIC DERIVATIVE. |
| FR2931661B1 (en) * | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | NOVEL DEPIGMENTING COMPOSITIONS IN THE FORM OF AN ANHYDROUS VASELIN - FREE AND ELASTOMER - FREE COMPOSITION COMPRISING A SOLUBILIZED PHENOLIC DERIVATIVE AND A RETINOID. |
| FR2949065B1 (en) | 2009-08-17 | 2011-10-21 | Natura Cosmeticos Sa | SKIN LIGHTENING COMPLEX, USE OF SAID COMPLEX, COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING SAID COMPLEX AND METHOD FOR APPLICATION THEREOF |
| CA2796412A1 (en) * | 2010-04-29 | 2011-11-03 | Galderma Research & Development | Method for treating scars with adapalene 0.3% |
| FR2969492B1 (en) * | 2010-12-23 | 2013-07-05 | Galderma Res & Dev | DERMATOLOGICAL FOAMS OBTAINED FROM GEL OR SUSPENSION CONTAINING ADAPALENE |
| RU2450836C1 (en) * | 2011-03-15 | 2012-05-20 | Закрытое акционерное общество Фармацевтическое научно-производственное предприятие "Ретиноиды" | Combined ointment composition for reducing intensity of local skin hyperpigmentation |
| GB2568758A (en) * | 2017-11-28 | 2019-05-29 | Chitty Nicholas | Sun protection and acne treatment and prevention composition |
| US12133907B2 (en) * | 2021-01-07 | 2024-11-05 | Actera Ingredients, Inc. | Lipophilic third generation retinoid |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3856934A (en) * | 1970-06-24 | 1974-12-24 | A Kligman | Skin depigmentation |
| US5194247A (en) * | 1989-08-24 | 1993-03-16 | Xina Nair | Synergistic skin depigmentation composition |
| FR2653336B1 (en) * | 1989-10-20 | 1994-04-08 | Oreal | PHARMACEUTICAL COMPOSITION AND DEPIGMENTANT COSMETICS BASED ON CAFEIC ACID. |
| US5395611A (en) * | 1990-04-24 | 1995-03-07 | The Governors Of The University Of Alberta | Phenolic amine depigmenting and antimelanoma agents |
| FR2714601B1 (en) * | 1993-12-30 | 1996-02-09 | Oreal | Depigmenting composition for the simultaneous treatment of surface and deep layers, its use. |
| US6068834A (en) * | 1994-03-04 | 2000-05-30 | The Procter & Gamble Company | Skin lightening compositions |
| FR2723315B1 (en) * | 1994-08-02 | 1996-10-25 | Cird Galderma | METHOD AND COMPOSITION FOR STIMULATING DIFFERENTIATION OF PREADIPOCYTE CELLS AND RELATED THERAPEUTIC TREATMENTS |
| FR2752734B1 (en) * | 1996-09-02 | 1998-11-06 | Cird Galderma | USE OF RETINOIDS FOR THE PREPARATION OF A MEDICAMENT FOR TREATING CONDITIONS RELATED TO VEGF OVEREXPRESSION |
| JP2000516643A (en) * | 1998-05-07 | 2000-12-12 | ザ、プロクター、エンド、ギャンブル、カンパニー | Composition containing ascorbic acid compound |
| CA2382022A1 (en) * | 1999-08-24 | 2001-03-01 | The Procter & Gamble Company | Methods of lightening keratinous tissue by topical application of oxime compound containing compositions |
| US20030077301A1 (en) * | 1999-12-16 | 2003-04-24 | Maibach Howard I. | Topical pharmaceutical composition for the treatment of inflammatory dermatoses |
| US20030147977A1 (en) * | 2000-05-03 | 2003-08-07 | Goodman David S. | Topical preparation for treating acne and hirsutism |
| US6358541B1 (en) * | 2000-05-03 | 2002-03-19 | David S. Goodman | Topical preparation for the treatment of hair loss |
| EP1317425B1 (en) * | 2000-09-11 | 2004-11-03 | Pfizer Products Inc. | Resorcinol derivatives |
| US7189759B2 (en) * | 2001-05-23 | 2007-03-13 | Medicis Pharmaceutical Corporation | Compositions for the treatment of pigmentation disorders and methods for their manufacture |
| US20030003142A1 (en) * | 2001-05-23 | 2003-01-02 | Wortzman Mitchell S. | Composition and method for the treatment of pigmentation disorders |
-
2003
- 2003-09-01 DK DK03750634T patent/DK1536763T3/en active
- 2003-09-01 MX MXPA05002064A patent/MXPA05002064A/en active IP Right Grant
- 2003-09-01 PT PT03750634T patent/PT1536763E/en unknown
- 2003-09-01 ES ES03750634T patent/ES2289315T3/en not_active Expired - Lifetime
- 2003-09-01 JP JP2004533511A patent/JP4662769B2/en not_active Expired - Fee Related
- 2003-09-01 EP EP03750634A patent/EP1536763B1/en not_active Expired - Lifetime
- 2003-09-01 CA CA002495043A patent/CA2495043A1/en not_active Abandoned
- 2003-09-01 AT AT03750634T patent/ATE366566T1/en active
- 2003-09-01 AU AU2003270272A patent/AU2003270272B2/en not_active Ceased
- 2003-09-01 CN CNB038212447A patent/CN100391432C/en not_active Expired - Fee Related
- 2003-09-01 RU RU2005109553/15A patent/RU2317066C2/en not_active IP Right Cessation
- 2003-09-01 DE DE60314887T patent/DE60314887T2/en not_active Expired - Lifetime
- 2003-09-01 PL PL377106A patent/PL377106A1/en not_active Application Discontinuation
- 2003-09-01 WO PCT/EP2003/010692 patent/WO2004021967A2/en not_active Ceased
- 2003-09-01 KR KR1020057003877A patent/KR20050057238A/en not_active Ceased
- 2003-09-01 BR BRPI0313370-2A patent/BR0313370B1/en not_active IP Right Cessation
-
2005
- 2005-01-26 US US11/042,519 patent/US20050163731A1/en not_active Abandoned
- 2005-03-01 ZA ZA2005/01753A patent/ZA200501753B/en unknown
-
2007
- 2007-09-12 CY CY20071101173T patent/CY1107732T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005109553A (en) | 2005-08-20 |
| EP1536763B1 (en) | 2007-07-11 |
| DE60314887T2 (en) | 2008-03-13 |
| CY1107732T1 (en) | 2013-04-18 |
| ZA200501753B (en) | 2007-01-31 |
| AU2003270272B2 (en) | 2008-06-19 |
| RU2317066C2 (en) | 2008-02-20 |
| JP4662769B2 (en) | 2011-03-30 |
| PT1536763E (en) | 2007-08-20 |
| US20050163731A1 (en) | 2005-07-28 |
| KR20050057238A (en) | 2005-06-16 |
| CA2495043A1 (en) | 2004-03-18 |
| EP1536763A2 (en) | 2005-06-08 |
| WO2004021967A3 (en) | 2005-02-17 |
| BR0313370B1 (en) | 2015-02-24 |
| MXPA05002064A (en) | 2005-06-08 |
| CN100391432C (en) | 2008-06-04 |
| AU2003270272A1 (en) | 2004-03-29 |
| ES2289315T3 (en) | 2008-02-01 |
| DE60314887D1 (en) | 2007-08-23 |
| JP2006511466A (en) | 2006-04-06 |
| WO2004021967A2 (en) | 2004-03-18 |
| DK1536763T3 (en) | 2007-11-05 |
| ATE366566T1 (en) | 2007-08-15 |
| BR0313370A (en) | 2006-04-18 |
| CN1681473A (en) | 2005-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |