PE35398A1 - 2-oxo y 2-tio-1,2-dihidroquinolinil-oxazolidinonas - Google Patents
2-oxo y 2-tio-1,2-dihidroquinolinil-oxazolidinonasInfo
- Publication number
- PE35398A1 PE35398A1 PE1997000019A PE00001997A PE35398A1 PE 35398 A1 PE35398 A1 PE 35398A1 PE 1997000019 A PE1997000019 A PE 1997000019A PE 00001997 A PE00001997 A PE 00001997A PE 35398 A1 PE35398 A1 PE 35398A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- formula
- vii
- hydrogen
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 239000011593 sulfur Substances 0.000 abstract 2
- -1 AZIDO, HYDROXYL Chemical group 0.000 abstract 1
- YLNSNVGRSIOCEU-ZCFIWIBFSA-N [(2r)-oxiran-2-yl]methyl butanoate Chemical compound CCCC(=O)OC[C@H]1CO1 YLNSNVGRSIOCEU-ZCFIWIBFSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
SE REFIEREN A ANTIBACTERIANOS DE FORMULA (I), EN DONDE: "A" ES OXIGENO O AZUFRE; "D" ES HIDROGENO, ALQUILO O ALQUENILO C1-C9 (OPCIONALMENTE SUSTITUIDOS POR CIANO O HIDROXILO), -(CO)a-NR2R3, -(CT)d-NR10R11, -(CO)e-NR12-CO-NR13R14 o -CO-R20, ENTRE OTROS, EN DONDE: "T" ES OXIGENO O AZUFRE; a, d Y e SON 0 o 1; R2, R3, R10, R11, R12, R13 Y R14 SON H o ALQUILO C1-C5, ENTRE OTROS; R20 ES ARILO C6-C10 OPCIONALMENTE SUSTITUIDO POR HALOGENO; "E" Y "L" PREFERENTEMENTE SON HIDROGENO; R1 ES AZIDO, HIDROXILO, -OR21, -O-SO2R22 o -NR23R24, EN DONDE: R21 ES ACILO C1-C6 o UN GRUPO PROTECTOR OH; R22 ES ALQUILO C1-C5, FENILO o TOLILO; R23 Y R24 SON HIDROGENO, ALCOXI C1-C6 o -CT`-R25, ENTRE OTROS, EN DONDE: T' ES COMO "T"; R25 ES CICLOALQUILO C3-C6, ALQUILO C1-C6, TIOALQUILO C1-C5 o ACILO C1-C5, ENTRE OTROS. TAMBIEN SE REFIERE A LOS COMPUESTOS INTERMEDIOS DE FORMULA (VII), A LOS N-1-OXIDOS DEL COMPUESTO (VII) Y AL COMPUESTO DE FORMULA (IV). ADEMAS SE REFIERE A LOS PROCEDIMIENTOS DE PREPARACION DE LOS COMPUESTOS DE FORMULA (I), QUE COMPRENDE: a) TRANSFORMAR LOS N-1-OXIDOS DEL COMPUESTO DE FORMULA (VII) MEDIANTE REACCION CON Ac2O o p-TsCl/CO3K2 EN DISOLVENTES INERTES, o b) TRANSFORMAR (IV) MEDIANTE REACCION CON ALQUIL-LITIO EN ETERES Y BUTIRATO DE R-GLICIDILO, Y OTROS PROCESOS PARA OBTENER LOS SUSTITUYENTES EN R1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19601265A DE19601265A1 (de) | 1996-01-16 | 1996-01-16 | 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE35398A1 true PE35398A1 (es) | 1998-08-29 |
Family
ID=7782816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000019A PE35398A1 (es) | 1996-01-16 | 1997-01-14 | 2-oxo y 2-tio-1,2-dihidroquinolinil-oxazolidinonas |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5861413A (es) |
| EP (1) | EP0785197A3 (es) |
| JP (1) | JPH09194478A (es) |
| KR (1) | KR970059174A (es) |
| AR (1) | AR005458A1 (es) |
| AU (1) | AU711924B2 (es) |
| BG (1) | BG62257B1 (es) |
| BR (1) | BR9700688A (es) |
| CA (1) | CA2194945A1 (es) |
| CO (1) | CO4520188A1 (es) |
| CZ (1) | CZ12897A3 (es) |
| DE (1) | DE19601265A1 (es) |
| EE (1) | EE9700019A (es) |
| HN (1) | HN1996000124A (es) |
| HR (1) | HRP960614A2 (es) |
| HU (1) | HUP9700126A3 (es) |
| IL (1) | IL119994A0 (es) |
| NO (1) | NO970174L (es) |
| NZ (1) | NZ314057A (es) |
| PE (1) | PE35398A1 (es) |
| PL (1) | PL317930A1 (es) |
| SG (1) | SG46764A1 (es) |
| SK (1) | SK5897A3 (es) |
| SV (1) | SV1997000002A (es) |
| TN (1) | TNSN97009A1 (es) |
| TR (1) | TR199601002A1 (es) |
| YU (1) | YU1097A (es) |
| ZA (1) | ZA97302B (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| DE19802239A1 (de) * | 1998-01-22 | 1999-07-29 | Bayer Ag | Neue mit Bicyclen substituierte Oxazolidinone |
| CN1288462A (zh) | 1998-01-23 | 2001-03-21 | 法玛西雅厄普约翰美国公司 | 噁唑烷酮组合库、组合物和制备方法 |
| KR20010052615A (ko) * | 1998-06-05 | 2001-06-25 | 다비드 에 질레스 | 옥사졸리디논 유도체, 이것의 제조 방법 및 이것을함유하는 약학 조성물 |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
| US6514529B2 (en) | 2000-03-22 | 2003-02-04 | Pharmacia & Upjohn Company | Oxazolidinone tablet formulation |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US6544991B2 (en) | 2000-06-30 | 2003-04-08 | Pharmacia & Upjohn Company | Compositions and methods for treating bacterial infections |
| JP2004518677A (ja) * | 2000-12-21 | 2004-06-24 | ファルマシア・アンド・アップジョン・カンパニー | 抗菌性キノロン誘導体および細菌感染を治療するためのその使用 |
| WO2003031443A1 (en) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety |
| WO2003031441A1 (en) * | 2001-10-04 | 2003-04-17 | Morphochen Aktiengesellschaft Für Kombinatorische Chemie | Multiple action compounds |
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| DE60304360T2 (de) * | 2002-08-12 | 2006-11-16 | Pharmacia & Upjohn Co. Llc, Kalamazoo | N-aryl-2-oxazolidinone und deren derivate |
| WO2004026848A1 (en) * | 2002-09-20 | 2004-04-01 | Lupin Limited | Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents |
| AR042086A1 (es) * | 2002-11-21 | 2005-06-08 | Upjohn Co | N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos |
| ATE411312T1 (de) * | 2002-12-04 | 2008-10-15 | Glaxo Group Ltd | Chinoline und stickstoffhaltige derivatedavon und deren verwendung als antibakterielle mittel |
| JP2006516989A (ja) * | 2003-02-07 | 2006-07-13 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体 |
| BRPI0407252A (pt) * | 2003-02-07 | 2006-01-31 | Warner Lambert Co | Agentes antibacterianos. |
| US20040204463A1 (en) * | 2003-04-01 | 2004-10-14 | Harris Christina Renee | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| US20070155714A1 (en) | 2003-04-30 | 2007-07-05 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections |
| DE10340485B4 (de) | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| JP2007516263A (ja) | 2003-12-18 | 2007-06-21 | モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー | オキサゾリジノン−キノロンハイブリッド抗生物質 |
| US7494578B2 (en) * | 2004-03-01 | 2009-02-24 | Atotech Deutschland Gmbh | Iron-phosphorus electroplating bath and method |
| AU2005270951A1 (en) * | 2004-08-06 | 2006-02-16 | Pharmacia & Upjohn Company Llc | Oxazolidinones containing oxindoles as antibacterial agents |
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| US20100144717A1 (en) * | 2006-12-15 | 2010-06-10 | Janelle Comita-Prevoir | 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents |
| TW200831517A (en) * | 2006-12-15 | 2008-08-01 | Astrazeneca Ab | Chemical compounds |
| RU2501799C2 (ru) * | 2008-02-22 | 2013-12-20 | Актелион Фармасьютикалз Лтд | Поизводные оксазолидинона |
| EP3177593A1 (en) * | 2014-08-06 | 2017-06-14 | Novartis AG | Quinolone derivatives as antibacterials |
| KR20220055171A (ko) * | 2020-10-26 | 2022-05-03 | 주식회사 아이비스바이오 | 포말리도마이드로부터 3,6'-디티오포말리도마이드를 선택적으로 합성하는 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
| US4801600A (en) | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US4965268A (en) * | 1987-10-09 | 1990-10-23 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US4942183A (en) * | 1987-10-16 | 1990-07-17 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| EP0609905B1 (en) | 1988-09-15 | 2001-06-06 | PHARMACIA & UPJOHN COMPANY | 3-(Nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones |
| JP2669579B2 (ja) * | 1991-10-23 | 1997-10-29 | エーザイ株式会社 | オキサゾリドン誘導体 |
| DE4332384A1 (de) | 1993-09-23 | 1995-03-30 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten III |
| TW286317B (es) * | 1993-12-13 | 1996-09-21 | Hoffmann La Roche | |
| DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
-
1996
- 1996-01-16 DE DE19601265A patent/DE19601265A1/de not_active Withdrawn
- 1996-12-12 TR TR96/01002A patent/TR199601002A1/xx unknown
- 1996-12-23 HR HR19601265.1A patent/HRP960614A2/hr not_active Application Discontinuation
- 1996-12-27 HN HN1996000124A patent/HN1996000124A/es unknown
-
1997
- 1997-01-03 EP EP97100026A patent/EP0785197A3/de not_active Withdrawn
- 1997-01-09 AU AU10097/97A patent/AU711924B2/en not_active Ceased
- 1997-01-09 US US08/781,002 patent/US5861413A/en not_active Expired - Fee Related
- 1997-01-13 JP JP9015889A patent/JPH09194478A/ja active Pending
- 1997-01-13 CA CA002194945A patent/CA2194945A1/en not_active Abandoned
- 1997-01-13 NZ NZ314057A patent/NZ314057A/en unknown
- 1997-01-13 IL IL11999497A patent/IL119994A0/xx unknown
- 1997-01-14 PE PE1997000019A patent/PE35398A1/es not_active Application Discontinuation
- 1997-01-14 BG BG101131A patent/BG62257B1/bg unknown
- 1997-01-14 YU YU1097A patent/YU1097A/sh unknown
- 1997-01-14 AR ARP970100134A patent/AR005458A1/es unknown
- 1997-01-14 PL PL97317930A patent/PL317930A1/xx unknown
- 1997-01-15 SG SG1997000088A patent/SG46764A1/en unknown
- 1997-01-15 HU HU9700126A patent/HUP9700126A3/hu unknown
- 1997-01-15 ZA ZA97302A patent/ZA97302B/xx unknown
- 1997-01-15 NO NO970174A patent/NO970174L/no unknown
- 1997-01-15 CZ CZ97128A patent/CZ12897A3/cs unknown
- 1997-01-15 TN TNTNSN97009A patent/TNSN97009A1/fr unknown
- 1997-01-15 KR KR1019970001029A patent/KR970059174A/ko not_active Withdrawn
- 1997-01-15 CO CO97001471A patent/CO4520188A1/es unknown
- 1997-01-15 SK SK58-97A patent/SK5897A3/sk unknown
- 1997-01-15 BR BR9700688A patent/BR9700688A/pt not_active Application Discontinuation
- 1997-01-15 EE EE9700019A patent/EE9700019A/xx unknown
- 1997-01-16 SV SV1997000002A patent/SV1997000002A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA97302B (en) | 1997-07-17 |
| TNSN97009A1 (fr) | 2005-03-15 |
| CA2194945A1 (en) | 1997-07-17 |
| HUP9700126A3 (en) | 1999-05-28 |
| KR970059174A (ko) | 1997-08-12 |
| TR199601002A1 (tr) | 1997-08-21 |
| NO970174D0 (no) | 1997-01-15 |
| SK5897A3 (en) | 1997-09-10 |
| HN1996000124A (es) | 1997-06-18 |
| BG62257B1 (bg) | 1999-06-30 |
| CO4520188A1 (es) | 1997-10-15 |
| NO970174L (no) | 1997-07-17 |
| US5861413A (en) | 1999-01-19 |
| DE19601265A1 (de) | 1997-07-17 |
| HRP960614A2 (en) | 1998-02-28 |
| AU711924B2 (en) | 1999-10-21 |
| HU9700126D0 (en) | 1997-02-28 |
| AU1009797A (en) | 1997-07-24 |
| EP0785197A2 (de) | 1997-07-23 |
| MX9700419A (es) | 1997-07-31 |
| IL119994A0 (en) | 1997-04-15 |
| YU1097A (sh) | 1999-12-27 |
| NZ314057A (en) | 1998-11-25 |
| SG46764A1 (en) | 1998-02-20 |
| HUP9700126A2 (hu) | 1998-12-28 |
| BR9700688A (pt) | 1998-09-01 |
| EP0785197A3 (de) | 1999-02-10 |
| PL317930A1 (en) | 1997-07-21 |
| JPH09194478A (ja) | 1997-07-29 |
| AR005458A1 (es) | 1999-06-23 |
| BG101131A (en) | 1998-04-30 |
| EE9700019A (et) | 1997-08-15 |
| SV1997000002A (es) | 1997-08-29 |
| CZ12897A3 (en) | 1997-08-13 |
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