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PE20251595A1 - PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS - Google Patents

PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS

Info

Publication number
PE20251595A1
PE20251595A1 PE2025000826A PE2025000826A PE20251595A1 PE 20251595 A1 PE20251595 A1 PE 20251595A1 PE 2025000826 A PE2025000826 A PE 2025000826A PE 2025000826 A PE2025000826 A PE 2025000826A PE 20251595 A1 PE20251595 A1 PE 20251595A1
Authority
PE
Peru
Prior art keywords
compound
formula
methoxy
synthesis
substituted benzaldehyde
Prior art date
Application number
PE2025000826A
Other languages
Spanish (es)
Inventor
Thomas Vettiger
Denis Gribkov
Matthias Maywald
Julia Augusta Tesson
Original Assignee
Syngenta Crop Protection Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Crop Protection Ag filed Critical Syngenta Crop Protection Ag
Publication of PE20251595A1 publication Critical patent/PE20251595A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se proporciona un proceso para la preparacion de un compuesto de formula (I), en donde, X es halogeno; que comprende las etapas de: (i) hacer reaccionar un compuesto de formula (II); en donde Y es Br, Cl, I, entre otros; R1 es alquilo C1-C6 y X es como se definio anteriormente para un compuesto de formula (I); con metanol en presencia de una fuente de cobre para dar un compuesto de formula (III); en donde X es como se definio anteriormente para un compuesto de formula (I) y R1 es como se definio anteriormente para un compuesto de formula (II); y, (ii) hidrolisis a un compuesto de formula (I).A process is provided for the preparation of a compound of formula (I), wherein X is halogen; comprising the steps of: (i) reacting a compound of formula (II); wherein Y is Br, Cl, I, among others; R1 is C1-C6 alkyl and X is as defined above for a compound of formula (I); with methanol in the presence of a copper source to give a compound of formula (III); wherein X is as defined above for a compound of formula (I) and R1 is as defined above for a compound of formula (II); and, (ii) hydrolysis to a compound of formula (I).

PE2025000826A 2022-10-28 2023-10-26 PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS PE20251595A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22204353 2022-10-28
PCT/EP2023/080025 WO2024089225A1 (en) 2022-10-28 2023-10-26 Process for the synthesis of methoxy substituted benzaldehyde compounds

Publications (1)

Publication Number Publication Date
PE20251595A1 true PE20251595A1 (en) 2025-06-16

Family

ID=88647473

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2025000826A PE20251595A1 (en) 2022-10-28 2023-10-26 PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS

Country Status (11)

Country Link
EP (1) EP4608796A1 (en)
CN (1) CN119948005A (en)
AR (1) AR130837A1 (en)
AU (1) AU2023366305A1 (en)
CL (1) CL2025001209A1 (en)
CO (1) CO2025005119A2 (en)
IL (1) IL319738A (en)
MX (1) MX2025004654A (en)
PE (1) PE20251595A1 (en)
UY (1) UY40501A (en)
WO (1) WO2024089225A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721643A1 (en) 1977-05-13 1978-11-23 Heumann Ludwig & Co Gmbh Prepn. of N-aminoalkyl-2-alkoxy-5-sulphamoyl-benzamide derivs. - useful as pharmaceuticals
JP3233678B2 (en) 1991-06-27 2001-11-26 日本化学工業株式会社 Method for producing o-alkoxybenzoic acid
GB201411418D0 (en) 2014-06-26 2014-08-13 Syngenta Participations Ag Compounds
US10500577B2 (en) 2015-07-20 2019-12-10 CE Pharm CO., LTD Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides

Also Published As

Publication number Publication date
CL2025001209A1 (en) 2025-08-18
CN119948005A (en) 2025-05-06
IL319738A (en) 2025-05-01
MX2025004654A (en) 2025-05-02
CO2025005119A2 (en) 2025-05-19
UY40501A (en) 2024-05-31
AR130837A1 (en) 2025-01-22
AU2023366305A1 (en) 2025-04-03
EP4608796A1 (en) 2025-09-03
WO2024089225A1 (en) 2024-05-02

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