PE20251595A1 - PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS - Google Patents
PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDSInfo
- Publication number
- PE20251595A1 PE20251595A1 PE2025000826A PE2025000826A PE20251595A1 PE 20251595 A1 PE20251595 A1 PE 20251595A1 PE 2025000826 A PE2025000826 A PE 2025000826A PE 2025000826 A PE2025000826 A PE 2025000826A PE 20251595 A1 PE20251595 A1 PE 20251595A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- formula
- methoxy
- synthesis
- substituted benzaldehyde
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Se proporciona un proceso para la preparacion de un compuesto de formula (I), en donde, X es halogeno; que comprende las etapas de: (i) hacer reaccionar un compuesto de formula (II); en donde Y es Br, Cl, I, entre otros; R1 es alquilo C1-C6 y X es como se definio anteriormente para un compuesto de formula (I); con metanol en presencia de una fuente de cobre para dar un compuesto de formula (III); en donde X es como se definio anteriormente para un compuesto de formula (I) y R1 es como se definio anteriormente para un compuesto de formula (II); y, (ii) hidrolisis a un compuesto de formula (I).A process is provided for the preparation of a compound of formula (I), wherein X is halogen; comprising the steps of: (i) reacting a compound of formula (II); wherein Y is Br, Cl, I, among others; R1 is C1-C6 alkyl and X is as defined above for a compound of formula (I); with methanol in the presence of a copper source to give a compound of formula (III); wherein X is as defined above for a compound of formula (I) and R1 is as defined above for a compound of formula (II); and, (ii) hydrolysis to a compound of formula (I).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22204353 | 2022-10-28 | ||
| PCT/EP2023/080025 WO2024089225A1 (en) | 2022-10-28 | 2023-10-26 | Process for the synthesis of methoxy substituted benzaldehyde compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20251595A1 true PE20251595A1 (en) | 2025-06-16 |
Family
ID=88647473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2025000826A PE20251595A1 (en) | 2022-10-28 | 2023-10-26 | PROCESS FOR THE SYNTHESIS OF METHOXY-SUBSTITUTED BENZALDEHYDE COMPOUNDS |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP4608796A1 (en) |
| CN (1) | CN119948005A (en) |
| AR (1) | AR130837A1 (en) |
| AU (1) | AU2023366305A1 (en) |
| CL (1) | CL2025001209A1 (en) |
| CO (1) | CO2025005119A2 (en) |
| IL (1) | IL319738A (en) |
| MX (1) | MX2025004654A (en) |
| PE (1) | PE20251595A1 (en) |
| UY (1) | UY40501A (en) |
| WO (1) | WO2024089225A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2721643A1 (en) | 1977-05-13 | 1978-11-23 | Heumann Ludwig & Co Gmbh | Prepn. of N-aminoalkyl-2-alkoxy-5-sulphamoyl-benzamide derivs. - useful as pharmaceuticals |
| JP3233678B2 (en) | 1991-06-27 | 2001-11-26 | 日本化学工業株式会社 | Method for producing o-alkoxybenzoic acid |
| GB201411418D0 (en) | 2014-06-26 | 2014-08-13 | Syngenta Participations Ag | Compounds |
| US10500577B2 (en) | 2015-07-20 | 2019-12-10 | CE Pharm CO., LTD | Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides |
-
2023
- 2023-10-23 AR ARP230102823A patent/AR130837A1/en unknown
- 2023-10-26 CN CN202380069194.8A patent/CN119948005A/en active Pending
- 2023-10-26 PE PE2025000826A patent/PE20251595A1/en unknown
- 2023-10-26 UY UY0001040501A patent/UY40501A/en unknown
- 2023-10-26 AU AU2023366305A patent/AU2023366305A1/en active Pending
- 2023-10-26 EP EP23798712.8A patent/EP4608796A1/en active Pending
- 2023-10-26 WO PCT/EP2023/080025 patent/WO2024089225A1/en not_active Ceased
- 2023-10-26 IL IL319738A patent/IL319738A/en unknown
-
2025
- 2025-04-22 MX MX2025004654A patent/MX2025004654A/en unknown
- 2025-04-23 CL CL2025001209A patent/CL2025001209A1/en unknown
- 2025-04-24 CO CONC2025/0005119A patent/CO2025005119A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2025001209A1 (en) | 2025-08-18 |
| CN119948005A (en) | 2025-05-06 |
| IL319738A (en) | 2025-05-01 |
| MX2025004654A (en) | 2025-05-02 |
| CO2025005119A2 (en) | 2025-05-19 |
| UY40501A (en) | 2024-05-31 |
| AR130837A1 (en) | 2025-01-22 |
| AU2023366305A1 (en) | 2025-04-03 |
| EP4608796A1 (en) | 2025-09-03 |
| WO2024089225A1 (en) | 2024-05-02 |
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