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PE20200892A1 - Excitacion con energia de luz de fluorescencia - Google Patents

Excitacion con energia de luz de fluorescencia

Info

Publication number
PE20200892A1
PE20200892A1 PE2019002653A PE2019002653A PE20200892A1 PE 20200892 A1 PE20200892 A1 PE 20200892A1 PE 2019002653 A PE2019002653 A PE 2019002653A PE 2019002653 A PE2019002653 A PE 2019002653A PE 20200892 A1 PE20200892 A1 PE 20200892A1
Authority
PE
Peru
Prior art keywords
light energy
excitation
fluorescent light
light
directed toward
Prior art date
Application number
PE2019002653A
Other languages
English (en)
Inventor
Rui Jiang
Joseph Pinto
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of PE20200892A1 publication Critical patent/PE20200892A1/es

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    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
    • H10F77/00—Constructional details of devices covered by this subclass
    • H10F77/40—Optical elements or arrangements
    • H10F77/42—Optical elements or arrangements directly associated or integrated with photovoltaic cells, e.g. light-reflecting means or light-concentrating means
    • H10F77/45—Wavelength conversion means, e.g. by using luminescent material, fluorescent concentrators or up-conversion arrangements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
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    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
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    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
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    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
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    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
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    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
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    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10F—INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Comprende una o mas fuentes de luz; un excitador de energia luminosa puede emitir luz de excitacion dirigida hacia la superficie del detector que puede soportar muestras biologicas o quimicas.
PE2019002653A 2017-12-28 2018-11-30 Excitacion con energia de luz de fluorescencia PE20200892A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762611448P 2017-12-28 2017-12-28
US201862644805P 2018-03-19 2018-03-19
NL2020636A NL2020636B1 (en) 2017-12-28 2018-03-20 Light energy fluorescence excitation
PCT/US2018/063401 WO2019133183A1 (en) 2017-12-28 2018-11-30 Light energy fluorescence excitation

Publications (1)

Publication Number Publication Date
PE20200892A1 true PE20200892A1 (es) 2020-09-07

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PE2019002653A PE20200892A1 (es) 2017-12-28 2018-11-30 Excitacion con energia de luz de fluorescencia

Country Status (25)

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US (3) US20190204227A1 (es)
EP (2) EP3505885B1 (es)
JP (1) JP7113856B2 (es)
KR (1) KR102424133B1 (es)
CN (2) CN109975256A (es)
AU (1) AU2018397466B2 (es)
CA (1) CA3085140A1 (es)
CL (1) CL2019003782A1 (es)
CO (1) CO2019014439A2 (es)
CR (1) CR20190585A (es)
DK (1) DK3505885T3 (es)
ES (1) ES2970587T3 (es)
FI (1) FI3505885T3 (es)
IL (1) IL271086B2 (es)
MX (1) MX2019015852A (es)
MY (1) MY198888A (es)
NL (1) NL2020636B1 (es)
PE (1) PE20200892A1 (es)
PH (1) PH12019502898A1 (es)
RU (1) RU2744934C1 (es)
SA (1) SA519410840B1 (es)
SG (1) SG11201911586SA (es)
TW (1) TWI729326B (es)
WO (1) WO2019133183A1 (es)
ZA (1) ZA201908035B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2020636B1 (en) 2017-12-28 2019-07-08 Illumina Inc Light energy fluorescence excitation
US11105745B2 (en) 2019-10-10 2021-08-31 Visera Technologies Company Limited Biosensor
CN112802832B (zh) * 2021-01-04 2023-06-02 业成科技（成都）有限公司 微发光二极体显示装置及其制造方法
WO2022217243A1 (en) * 2021-04-07 2022-10-13 Illumina, Inc. Adaptable illumination pattern for sample analysis
WO2023205729A1 (en) * 2022-04-22 2023-10-26 Illumina, Inc. Polarization based sensing
EP4609178A1 (en) * 2022-10-27 2025-09-03 Illumina, Inc. Light energy exciter

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2142332A1 (en) 1992-08-13 1994-03-03 Meinrad Machler Spectroscopic systems for the analysis of small and very small quantities of substances
CN1609593B (zh) * 1996-08-16 2012-04-25 Ge保健尼亚加拉公司 用于分析井板、凝胶和斑点的数字成像系统
US6654119B1 (en) * 1999-04-21 2003-11-25 Chromagen, Inc. Scanning spectrophotometer for high throughput fluroescence detection
AU5875900A (en) * 1999-06-18 2001-01-09 Genomic Solutions, Inc. An automated, ccd-based microarray imaging system
US6784982B1 (en) * 1999-11-04 2004-08-31 Regents Of The University Of Minnesota Direct mapping of DNA chips to detector arrays
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
US7697975B2 (en) * 2003-06-03 2010-04-13 British Colombia Cancer Agency Methods and apparatus for fluorescence imaging using multiple excitation-emission pairs and simultaneous multi-channel image detection
US7226831B1 (en) 2005-12-27 2007-06-05 Intel Corporation Device with scavenging spacer layer
CN101470075B (zh) * 2007-12-26 2012-04-11 深圳迈瑞生物医疗电子股份有限公司 气体浓度测量装置
CN102165305B (zh) * 2008-09-25 2014-08-20 皇家飞利浦电子股份有限公司 检测系统与方法
TWI378237B (en) * 2008-10-21 2012-12-01 Ind Tech Res Inst Apparatus for identifying a single biomolecule, apparatus for identifying biomolecules and method for identifying a single biomolecule
CN101571479B (zh) * 2009-06-16 2010-12-01 哈尔滨工程大学 基于线阵ccd的光学液体浓度测量装置及测量方法
AU2011217862B9 (en) 2010-02-19 2014-07-10 Pacific Biosciences Of California, Inc. Integrated analytical system and method
US8403527B2 (en) * 2010-10-26 2013-03-26 Thomas J. Brukilacchio Light emitting diode projector
AT510824B1 (de) * 2010-11-23 2016-05-15 Swarco Futurit Verkehrssignalsysteme Ges M B H Farbmischende sammeloptik
EP3290528B1 (en) * 2011-09-23 2019-08-14 Illumina, Inc. Methods and compositions for nucleic acid sequencing
JP2013092393A (ja) * 2011-10-24 2013-05-16 Sony Corp ケミカルセンサ、生体分子検出装置及び生体分子検出方法
US8906320B1 (en) 2012-04-16 2014-12-09 Illumina, Inc. Biosensors for biological or chemical analysis and systems and methods for same
WO2014017067A1 (ja) * 2012-07-27 2014-01-30 株式会社ニコン 構造化照明装置及び構造化照明顕微鏡
TWI593950B (zh) * 2012-11-13 2017-08-01 唯亞威方案公司 可攜式光譜儀
AU2014364006B2 (en) 2013-12-10 2019-07-11 Illumina, Inc. Biosensors for biological or chemical analysis and methods of manufacturing the same
US9606068B2 (en) 2014-08-27 2017-03-28 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices
WO2016127128A1 (en) * 2015-02-06 2016-08-11 Life Technologies Corporation Systems and methods for assessing biological samples
KR20180019500A (ko) * 2015-04-22 2018-02-26 선전 제노리비전 테크놀로지 컴퍼니, 리미티드 생물감지기
CN108449958A (zh) * 2015-09-01 2018-08-24 凯杰器械有限公司 高通量核酸测序系统中用于颜色探测的系统和方法
NL2020636B1 (en) 2017-12-28 2019-07-08 Illumina Inc Light energy fluorescence excitation

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