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PE20181176A1 - Composiciones biofarmaceuticas - Google Patents

Composiciones biofarmaceuticas

Info

Publication number
PE20181176A1
PE20181176A1 PE2018000264A PE2018000264A PE20181176A1 PE 20181176 A1 PE20181176 A1 PE 20181176A1 PE 2018000264 A PE2018000264 A PE 2018000264A PE 2018000264 A PE2018000264 A PE 2018000264A PE 20181176 A1 PE20181176 A1 PE 20181176A1
Authority
PE
Peru
Prior art keywords
antibody
amino acid
acid sequence
sequence seq
chain amino
Prior art date
Application number
PE2018000264A
Other languages
English (en)
Inventor
Myrna A Monck
Narendra B Bam
Jennifer Dally
Michelle Spatara
Original Assignee
Glaxosmithkline Ip No 2 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56877084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20181176(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Ip No 2 Ltd filed Critical Glaxosmithkline Ip No 2 Ltd
Publication of PE20181176A1 publication Critical patent/PE20181176A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Referido a una composicion que comprende un anticuerpo que tiene una secuencia de aminoacidos de cadena pesada SEQ ID NO: 1, una secuencia de aminoacidos de cadena ligera SEQ ID NO: 2 o una variante del mismo; y un vehiculo farmaceuticamente aceptable; donde el anticuerpo es anti-interleuquina 5 (anti-IL-5), siendo utiles para el tratamiento de enfermedades mediadas por IL-5, y metodos relacionados a su preparacion.
PE2018000264A 2015-08-24 2016-08-22 Composiciones biofarmaceuticas PE20181176A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562209000P 2015-08-24 2015-08-24
US201562240131P 2015-10-12 2015-10-12
US201562247906P 2015-10-29 2015-10-29
US201562249497P 2015-11-02 2015-11-02

Publications (1)

Publication Number Publication Date
PE20181176A1 true PE20181176A1 (es) 2018-07-20

Family

ID=56877084

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2018000264A PE20181176A1 (es) 2015-08-24 2016-08-22 Composiciones biofarmaceuticas

Country Status (22)

Country Link
US (10) US10870695B2 (es)
EP (2) EP4056590B1 (es)
JP (4) JP6821659B2 (es)
KR (3) KR20180037275A (es)
CN (5) CN108137683A (es)
AU (1) AU2016311385C1 (es)
BR (1) BR112018003741A2 (es)
CA (1) CA2996088A1 (es)
CL (1) CL2018000499A1 (es)
CO (1) CO2018001840A2 (es)
CR (1) CR20180115A (es)
DO (1) DOP2018000057A (es)
EA (1) EA037487B1 (es)
IL (1) IL257539A (es)
MA (1) MA42692A (es)
MX (2) MX2018002319A (es)
PE (1) PE20181176A1 (es)
PH (1) PH12018500379B1 (es)
TW (2) TWI780988B (es)
UY (1) UY36868A (es)
WO (1) WO2017033121A1 (es)
ZA (1) ZA201801158B (es)

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MA44334A (fr) 2015-10-29 2018-09-05 Novartis Ag Conjugués d'anticorps comprenant un agoniste du récepteur de type toll
KR102826635B1 (ko) * 2016-06-17 2025-06-30 제넨테크, 인크. 다중 특이적 항체의 정제
KR102651290B1 (ko) 2016-12-23 2024-03-25 세파론 엘엘씨 항-il-5 항체
PE20191844A1 (es) * 2017-05-26 2019-12-31 Glaxosmithkline Ip Dev Ltd Composiciones biofarmaceuticas y metodos relacionados
CN119632921A (zh) * 2017-06-06 2025-03-18 葛兰素史克有限责任公司 用于儿科患者的生物药物组合物和方法
TWI801425B (zh) * 2017-09-29 2023-05-11 大陸商江蘇恆瑞醫藥股份有限公司 Il-5 抗體、其抗原結合片段及醫藥用途
WO2019224724A1 (en) * 2018-05-23 2019-11-28 Glaxosmithkline Intellectual Property Development Limited Biopharmaceutical compositions comprising antibody variants
AU2020251627A1 (en) 2019-03-29 2021-11-11 Jiangsu Hengrui Medicine Co., Ltd. Pharmaceutical composition containing antibody against IL-5 and use thereof
US20210008199A1 (en) * 2019-07-10 2021-01-14 Regeneron Pharmaceuticals, Inc. Methods and compositions comprising reduced level of host cell proteins
EP4077388A1 (en) * 2019-12-18 2022-10-26 Tesaro, Inc. Biopharmaceutical compositions and related methods
EP4272756A4 (en) * 2021-02-05 2024-12-11 Bio-Thera Solutions, Ltd. ANTI-IL-5 ANTIBODY FORMULATION, MANUFACTURING METHOD AND USE THEREOF
JP2024527586A (ja) * 2021-07-09 2024-07-25 ヤンセン バイオテツク，インコーポレーテツド 抗－ｔｎｆ抗体組成物を産生するための製造方法
WO2023049803A1 (en) * 2021-09-22 2023-03-30 Sonoma Biotherapeutics, Inc. Il5ra cell surface markers

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TWI780988B (zh) 2015-08-24 2022-10-11 英商葛蘭素史密斯克藍智慧財產權有限公司 生藥組成物

Also Published As

Publication number Publication date
KR20240099511A (ko) 2024-06-28
JP2024123040A (ja) 2024-09-10
US20180251539A1 (en) 2018-09-06
JP2020033351A (ja) 2020-03-05
IL257539A (en) 2018-04-30
US20240294630A1 (en) 2024-09-05
JP7463070B2 (ja) 2024-04-08
CO2018001840A2 (es) 2018-05-31
EA201890572A1 (ru) 2018-10-31
BR112018003741A2 (pt) 2018-09-25
US20240294629A1 (en) 2024-09-05
EA037487B1 (ru) 2021-04-02
TWI750133B (zh) 2021-12-21
PH12018500379A1 (en) 2018-09-03
CN116327923A (zh) 2023-06-27
KR20180037275A (ko) 2018-04-11
JP2022023049A (ja) 2022-02-07
DOP2018000057A (es) 2018-03-15
MA42692A (fr) 2018-07-04
US20200199219A1 (en) 2020-06-25
US20240294628A1 (en) 2024-09-05
CN108137683A (zh) 2018-06-08
TW201722473A (zh) 2017-07-01
US20210340246A1 (en) 2021-11-04
US20220185878A1 (en) 2022-06-16
CN116474091A (zh) 2023-07-25
US12187789B2 (en) 2025-01-07
CN116327921A (zh) 2023-06-27
US20220380452A1 (en) 2022-12-01
US12454571B2 (en) 2025-10-28
US12187790B2 (en) 2025-01-07
US10870695B2 (en) 2020-12-22
PH12018500379B1 (en) 2022-11-23
US20210340247A1 (en) 2021-11-04
US11299541B2 (en) 2022-04-12
NZ739899A (en) 2025-05-02
AU2016311385C1 (en) 2019-08-22
ZA201801158B (en) 2019-08-28
EP4056590A1 (en) 2022-09-14
AU2016311385B2 (en) 2019-05-09
EP3341409A1 (en) 2018-07-04
EP4056590B1 (en) 2025-10-15
UY36868A (es) 2017-03-31
US20210332125A1 (en) 2021-10-28
CR20180115A (es) 2018-04-12
JP6821659B2 (ja) 2021-01-27
WO2017033121A1 (en) 2017-03-02
US11459384B2 (en) 2022-10-04
AU2016311385A1 (en) 2018-03-15
CN116327922A (zh) 2023-06-27
MX2018002319A (es) 2018-04-11
US11274148B2 (en) 2022-03-15
MX2024001617A (es) 2024-03-06
CL2018000499A1 (es) 2018-07-06
US12187791B2 (en) 2025-01-07
US11286298B2 (en) 2022-03-29
TW202233238A (zh) 2022-09-01
TWI780988B (zh) 2022-10-11
KR20250086801A (ko) 2025-06-13
CA2996088A1 (en) 2017-03-02
JP2018526369A (ja) 2018-09-13

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