PE20180463A1 - Virus de la enteritis del pato y usos del mismo - Google Patents
Virus de la enteritis del pato y usos del mismoInfo
- Publication number
- PE20180463A1 PE20180463A1 PE2017002892A PE2017002892A PE20180463A1 PE 20180463 A1 PE20180463 A1 PE 20180463A1 PE 2017002892 A PE2017002892 A PE 2017002892A PE 2017002892 A PE2017002892 A PE 2017002892A PE 20180463 A1 PE20180463 A1 PE 20180463A1
- Authority
- PE
- Peru
- Prior art keywords
- refers
- enteritis virus
- duck enteritis
- virus
- dev
- Prior art date
Links
- 241001492342 Anatid alphaherpesvirus 1 Species 0.000 title abstract 4
- 101150042941 UL4 gene Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 241000271566 Aves Species 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 235000013330 chicken meat Nutrition 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 235000013594 poultry meat Nutrition 0.000 abstract 1
- 230000003362 replicative effect Effects 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16361—Methods of inactivation or attenuation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16361—Methods of inactivation or attenuation
- C12N2710/16362—Methods of inactivation or attenuation by genetic engineering
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se refiere a una nueva construccion del virus de la enteritis de pato (DEV), en el que dicho virus tiene un gen UL4 inactivo, el cual esta mutado, eliminado o interrumpido, y adicionalmente comprende un acido nucleico extrano localizado en el gen UL4 que codifica un antigeno o una molecula inmunoestimulante, preferentemente un antigeno de un patogeno aviar. Tambien se refiere a una celula huesped y a un metodo para producirlo o replicarlo; tambien se refiere a un kit de vacunacion. Dicho DEV se utiliza generalmente para vacunar o inmunizar aves de corral, preferiblemente pollos
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15174515 | 2015-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20180463A1 true PE20180463A1 (es) | 2018-03-06 |
Family
ID=53496539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017002892A PE20180463A1 (es) | 2015-06-30 | 2016-06-29 | Virus de la enteritis del pato y usos del mismo |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US10202582B2 (es) |
| EP (1) | EP3317406A1 (es) |
| JP (1) | JP6802813B2 (es) |
| CN (1) | CN108368488B (es) |
| CA (1) | CA2992158C (es) |
| MX (1) | MX381252B (es) |
| PE (1) | PE20180463A1 (es) |
| RU (1) | RU2721575C2 (es) |
| UA (1) | UA122339C2 (es) |
| WO (1) | WO2017001469A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6802813B2 (ja) * | 2015-06-30 | 2020-12-23 | セヴァ・サンテ・アニマールCeva Sante Animale | アヒル腸炎ウイルス及びその使用 |
| EP3263129A1 (en) * | 2016-06-29 | 2018-01-03 | Ceva Sante Animale | Duck enteritis virus and the uses thereof |
| CN110904058B (zh) * | 2018-09-14 | 2023-03-07 | 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) | 重组鸭瘟病毒疫苗及其构建方法和应用 |
| JP2023520889A (ja) * | 2020-03-31 | 2023-05-22 | グレイル エルエルシー | ゲノム領域モデリングによるがん分類 |
| CN113249340B (zh) * | 2020-08-19 | 2022-07-19 | 浙江省农业科学院 | 一株双色荧光蛋白标记鸭瘟病毒及其构建方法和应用 |
| TW202523838A (zh) * | 2023-08-25 | 2025-06-16 | 大陸商勃林格殷格翰動物保健(中國)有限公司 | 新型dev載體 |
| WO2025044922A2 (en) * | 2023-08-25 | 2025-03-06 | Boehringer Ingelheim Vetmedica (China) Co., Ltd. | Vectored dev avian influenza h9 vaccines |
| WO2025044920A2 (en) * | 2023-08-25 | 2025-03-06 | Boehringer Ingelheim Vetmedica (China) Co., Ltd. | New dev vectors for avian vaccines |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2757061B1 (fr) | 1996-12-16 | 1999-03-26 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire |
| EP2140879A1 (en) * | 2001-05-09 | 2010-01-06 | M'S Science Corporation | Composition and method for treating cancer using herpes virus |
| FR2916759B1 (fr) * | 2007-05-29 | 2009-07-10 | Adisseo France Sas Soc Par Act | Peptide rumc presentant une activite antimicrobienne |
| CN102277368B (zh) * | 2010-06-13 | 2013-12-25 | 中国农业科学院哈尔滨兽医研究所 | 鸭病毒性肠炎病毒感染性重组克隆系统及构建方法和应用 |
| CN102533674B (zh) * | 2010-12-08 | 2014-05-14 | 中国农业科学院哈尔滨兽医研究所 | 表达禽流感病毒血凝素基因的重组鸭病毒性肠炎病毒疫苗株及其构建方法和应用 |
| CN103667351B (zh) * | 2012-09-10 | 2017-01-25 | 中国农业科学院哈尔滨兽医研究所 | 以鸭病毒性肠炎病毒疫苗株为载体的重组病毒疫苗在鸡形目禽类中的应用 |
| WO2014036735A1 (zh) | 2012-09-10 | 2014-03-13 | 中国农业科学院哈尔滨兽医研究所 | 鸭病毒性肠炎病毒疫苗株作为表达载体在制备预防鸡形目禽类疾病的重组病毒疫苗中的应用 |
| JP6802813B2 (ja) * | 2015-06-30 | 2020-12-23 | セヴァ・サンテ・アニマールCeva Sante Animale | アヒル腸炎ウイルス及びその使用 |
| EP3263129A1 (en) | 2016-06-29 | 2018-01-03 | Ceva Sante Animale | Duck enteritis virus and the uses thereof |
-
2016
- 2016-06-29 JP JP2017567689A patent/JP6802813B2/ja active Active
- 2016-06-29 US US15/740,824 patent/US10202582B2/en active Active
- 2016-06-29 RU RU2018103145A patent/RU2721575C2/ru active
- 2016-06-29 WO PCT/EP2016/065132 patent/WO2017001469A1/en not_active Ceased
- 2016-06-29 UA UAA201800821A patent/UA122339C2/uk unknown
- 2016-06-29 EP EP16733511.6A patent/EP3317406A1/en active Pending
- 2016-06-29 CA CA2992158A patent/CA2992158C/en active Active
- 2016-06-29 MX MX2018000091A patent/MX381252B/es unknown
- 2016-06-29 CN CN201680050454.7A patent/CN108368488B/zh active Active
- 2016-06-29 PE PE2017002892A patent/PE20180463A1/es unknown
-
2019
- 2019-01-18 US US16/251,115 patent/US10704028B2/en active Active
- 2019-01-18 US US16/251,108 patent/US10711254B2/en active Active
- 2019-01-18 US US16/251,111 patent/US10717967B2/en active Active
- 2019-01-18 US US16/251,113 patent/US10711255B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20190136208A1 (en) | 2019-05-09 |
| MX2018000091A (es) | 2018-02-19 |
| WO2017001469A1 (en) | 2017-01-05 |
| UA122339C2 (uk) | 2020-10-26 |
| US10202582B2 (en) | 2019-02-12 |
| CN108368488A (zh) | 2018-08-03 |
| CA2992158C (en) | 2023-11-21 |
| JP6802813B2 (ja) | 2020-12-23 |
| CA2992158A1 (en) | 2017-01-05 |
| RU2018103145A (ru) | 2019-07-30 |
| MX381252B (es) | 2025-03-11 |
| US20180187164A1 (en) | 2018-07-05 |
| US10711255B2 (en) | 2020-07-14 |
| US20190144835A1 (en) | 2019-05-16 |
| CN108368488B (zh) | 2022-04-05 |
| JP2018519826A (ja) | 2018-07-26 |
| US10717967B2 (en) | 2020-07-21 |
| BR112017028420A2 (pt) | 2018-08-28 |
| US10704028B2 (en) | 2020-07-07 |
| RU2018103145A3 (es) | 2019-11-20 |
| RU2721575C2 (ru) | 2020-05-20 |
| US10711254B2 (en) | 2020-07-14 |
| EP3317406A1 (en) | 2018-05-09 |
| US20190144836A1 (en) | 2019-05-16 |
| US20190136209A1 (en) | 2019-05-09 |
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