PE20170467A1 - Derivado de macrolido sustituido en la posicion c-4 - Google Patents
Derivado de macrolido sustituido en la posicion c-4Info
- Publication number
- PE20170467A1 PE20170467A1 PE2017000130A PE2017000130A PE20170467A1 PE 20170467 A1 PE20170467 A1 PE 20170467A1 PE 2017000130 A PE2017000130 A PE 2017000130A PE 2017000130 A PE2017000130 A PE 2017000130A PE 20170467 A1 PE20170467 A1 PE 20170467A1
- Authority
- PE
- Peru
- Prior art keywords
- derivative
- macrolido
- substitute
- refers
- antibacterial activity
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241001430197 Mollicutes Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003276 erythromycin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Se refiere a un derivado macrolido de formula 1, un hidrato, un solvato o una sal farmaceuticamente aceptable del mismo. Tambien se refiere a una composicion farmaceutica. Dicho compuesto presenta una actividad antibacteriana superior contra bacterias resistentes a la eritromicina tales como neumococos resistentes, estreptococos, micoplasmas y similares, contra las cuales no se puede obtener una actividad antibacteriana suficiente con los antibioticos de macrolidos convencionales
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014165848 | 2014-08-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20170467A1 true PE20170467A1 (es) | 2017-04-26 |
Family
ID=55350700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2017000130A PE20170467A1 (es) | 2014-08-18 | 2015-08-17 | Derivado de macrolido sustituido en la posicion c-4 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20170267708A1 (es) |
| EP (1) | EP3192798A4 (es) |
| JP (1) | JP5874871B1 (es) |
| KR (1) | KR20170036106A (es) |
| CN (1) | CN106573953A (es) |
| AR (1) | AR102810A1 (es) |
| AU (1) | AU2015304439A1 (es) |
| BR (1) | BR112017000606A2 (es) |
| CA (1) | CA2957628A1 (es) |
| CL (1) | CL2017000395A1 (es) |
| CO (1) | CO2017002440A2 (es) |
| IL (1) | IL250559A0 (es) |
| MX (1) | MX2017002223A (es) |
| PE (1) | PE20170467A1 (es) |
| PH (1) | PH12017500223A1 (es) |
| RU (1) | RU2017108908A (es) |
| SG (1) | SG11201701146TA (es) |
| TW (1) | TW201625656A (es) |
| WO (1) | WO2016027755A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017142002A1 (ja) * | 2016-02-17 | 2017-08-24 | 大正製薬株式会社 | Ｃ－４"位置換マクロライド化合物フリー体及び塩の結晶形並びにそれらの製造方法 |
| CN114231430B (zh) * | 2021-06-11 | 2024-02-09 | 常州大学 | 一种红霉素降解菌iurm f57及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54967A (en) | 1977-06-06 | 1979-01-06 | Mitsubishi Electric Corp | Output circuit |
| YU43006B (en) | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| KR100576988B1 (ko) | 1996-09-04 | 2006-05-10 | 아보트 러보러터리즈 | 항균 활성을 지닌 6-ｏ-치환된 케톨라이드 |
| HN1998000074A (es) | 1997-06-11 | 1999-01-08 | Pfizer Prod Inc | Derivados de macrolidos c-4 sustituidos |
| UY26964A1 (es) | 2000-10-16 | 2002-06-20 | Abbott Lab | Derivados de eritromicina 6-0-sustituidos con mayor tolerancia gastrointestinal |
| AR085286A1 (es) | 2011-02-21 | 2013-09-18 | Taisho Pharmaceutical Co Ltd | Derivado de macrolido sustituido en la posicion c-4 |
| JP5857008B2 (ja) * | 2012-08-20 | 2016-02-10 | 大正製薬株式会社 | Ｃ−４”位置換マクロライド誘導体を含有する医薬 |
| JP2014058508A (ja) * | 2012-08-20 | 2014-04-03 | Taisho Pharmaceutical Co Ltd | ９位オキシム置換マクロライド誘導体 |
| JP2014058507A (ja) * | 2012-08-20 | 2014-04-03 | Taisho Pharmaceutical Co Ltd | １１位アミノ置換マクロライド誘導体 |
-
2015
- 2015-08-14 AR ARP150102636A patent/AR102810A1/es unknown
- 2015-08-17 TW TW104126709A patent/TW201625656A/zh unknown
- 2015-08-17 US US15/504,946 patent/US20170267708A1/en not_active Abandoned
- 2015-08-17 BR BR112017000606A patent/BR112017000606A2/pt not_active Application Discontinuation
- 2015-08-17 AU AU2015304439A patent/AU2015304439A1/en not_active Abandoned
- 2015-08-17 RU RU2017108908A patent/RU2017108908A/ru unknown
- 2015-08-17 CN CN201580043943.5A patent/CN106573953A/zh active Pending
- 2015-08-17 PE PE2017000130A patent/PE20170467A1/es not_active Application Discontinuation
- 2015-08-17 WO PCT/JP2015/072993 patent/WO2016027755A1/ja not_active Ceased
- 2015-08-17 CA CA2957628A patent/CA2957628A1/en not_active Abandoned
- 2015-08-17 EP EP15833877.2A patent/EP3192798A4/en not_active Withdrawn
- 2015-08-17 KR KR1020177007145A patent/KR20170036106A/ko not_active Withdrawn
- 2015-08-17 MX MX2017002223A patent/MX2017002223A/es unknown
- 2015-08-17 SG SG11201701146TA patent/SG11201701146TA/en unknown
- 2015-08-17 JP JP2015545549A patent/JP5874871B1/ja not_active Expired - Fee Related
-
2017
- 2017-02-07 PH PH12017500223A patent/PH12017500223A1/en unknown
- 2017-02-12 IL IL250559A patent/IL250559A0/en unknown
- 2017-02-16 CL CL2017000395A patent/CL2017000395A1/es unknown
- 2017-03-14 CO CONC2017/0002440A patent/CO2017002440A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112017000606A2 (pt) | 2017-11-07 |
| RU2017108908A (ru) | 2018-09-21 |
| CA2957628A1 (en) | 2016-02-25 |
| EP3192798A1 (en) | 2017-07-19 |
| US20170267708A1 (en) | 2017-09-21 |
| TW201625656A (zh) | 2016-07-16 |
| KR20170036106A (ko) | 2017-03-31 |
| PH12017500223A1 (en) | 2017-07-10 |
| JPWO2016027755A1 (ja) | 2017-04-27 |
| CL2017000395A1 (es) | 2018-01-05 |
| EP3192798A4 (en) | 2018-01-03 |
| CO2017002440A2 (es) | 2017-04-28 |
| SG11201701146TA (en) | 2017-03-30 |
| WO2016027755A1 (ja) | 2016-02-25 |
| AU2015304439A1 (en) | 2017-03-16 |
| IL250559A0 (en) | 2017-03-30 |
| AR102810A1 (es) | 2017-03-29 |
| MX2017002223A (es) | 2017-05-09 |
| CN106573953A (zh) | 2017-04-19 |
| JP5874871B1 (ja) | 2016-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |