PE20151298A1 - Composiciones oticas utiles para el tratamiento de infecciones del oido interno y externo en mamiferos - Google Patents
Composiciones oticas utiles para el tratamiento de infecciones del oido interno y externo en mamiferosInfo
- Publication number
- PE20151298A1 PE20151298A1 PE2015001315A PE2015001315A PE20151298A1 PE 20151298 A1 PE20151298 A1 PE 20151298A1 PE 2015001315 A PE2015001315 A PE 2015001315A PE 2015001315 A PE2015001315 A PE 2015001315A PE 20151298 A1 PE20151298 A1 PE 20151298A1
- Authority
- PE
- Peru
- Prior art keywords
- concentration
- mammals
- treatment
- internal
- external ear
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title abstract 2
- 210000000883 ear external Anatomy 0.000 title abstract 2
- 210000003027 ear inner Anatomy 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- XMEKHKCRNHDFOW-UHFFFAOYSA-N O.O.[Na].[Na] Chemical compound O.O.[Na].[Na] XMEKHKCRNHDFOW-UHFFFAOYSA-N 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 210000000959 ear middle Anatomy 0.000 abstract 1
- 229940009662 edetate Drugs 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 229910052938 sodium sulfate Inorganic materials 0.000 abstract 1
- 235000011152 sodium sulphate Nutrition 0.000 abstract 1
- 239000008223 sterile water Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONSISTE DE: A) YODOPOVIDONA (PVP-I) A CONCENTRACION DE 2.0% (w/w); B) DEXAMETASONA A CONCENTRACION DE 0.1% (w/w); C) DIHIDRATO DISODICO EDETATO A CONCENTRACION DE 0.01% (w/w); D) CLORURO DE SODIO A CONCENTRACION DE 0.35% (w/w); E) TILOXAPOL A CONCENTRACION DE 0.05% (w/w); F) SULFATO DE SODIO A CONCENTRACION DE 1.2% (w/w); G) HIDROXIETILCELULOSA A CONCENTRACION DE 0.25% (w/w); Y H) AGUA ESTERIL. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE INFECCIONES BACTERIANAS AGUDAS Y CRONICAS, VIRALES Y FUNGICAS DEL OIDO INTERNO, MEDIO Y EXTERNO DE MAMIFEROS, INCLUYENDO SERES HUMANOS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/380,463 US20090263345A1 (en) | 2008-01-28 | 2009-02-27 | Otic compositions for the treatment of infections of the internal and external ear in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20151298A1 true PE20151298A1 (es) | 2015-10-10 |
Family
ID=44834943
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2015001315A PE20151298A1 (es) | 2009-02-27 | 2010-02-24 | Composiciones oticas utiles para el tratamiento de infecciones del oido interno y externo en mamiferos |
| PE2011001555A PE20120183A1 (es) | 2009-02-27 | 2010-02-24 | Composiciones oticas que comprenden yodopovidona en combinacion con un esteroide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011001555A PE20120183A1 (es) | 2009-02-27 | 2010-02-24 | Composiciones oticas que comprenden yodopovidona en combinacion con un esteroide |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20090263345A1 (es) |
| EP (2) | EP3673736A1 (es) |
| JP (3) | JP5714512B2 (es) |
| KR (4) | KR20110133479A (es) |
| CN (2) | CN105362286A (es) |
| AU (3) | AU2010218108B2 (es) |
| BR (1) | BRPI1012230A2 (es) |
| CA (1) | CA2753964C (es) |
| CL (1) | CL2011002091A1 (es) |
| CO (1) | CO6450663A2 (es) |
| EC (1) | ECSP11011354A (es) |
| MX (1) | MX2011008920A (es) |
| NZ (1) | NZ594884A (es) |
| PE (2) | PE20151298A1 (es) |
| WO (1) | WO2010099212A1 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7767217B2 (en) | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| US20130177522A1 (en) * | 2009-12-15 | 2013-07-11 | Foresight Biotherapeutics, Inc. | Non-irritating opthalmic povidone-iodine compositions |
| AU2015252097A1 (en) * | 2009-12-15 | 2015-11-19 | Foresight Biotherapeutics, Inc. | Non-irritating ophthalmic povidone-iodine compositions |
| US20170071979A1 (en) * | 2011-05-11 | 2017-03-16 | Veloce Biopharma, Llc | Composition and method for treating otitis |
| JP6077527B2 (ja) * | 2011-05-11 | 2017-02-08 | ヴェローチェ・バイオファーマ・エルエルシー | 皮膚および爪の治療のための抗真菌組成物 |
| WO2012177251A1 (en) * | 2011-06-22 | 2012-12-27 | Adeda Therapeutics Company Limited | Pharmaceutical compositions comprising iodine and steroid and uses thereof for sinus diseases |
| TW201325601A (zh) * | 2011-09-16 | 2013-07-01 | Foresight Biotherapeutics Inc | 安定之普維酮－碘組成物 |
| CN102429862B (zh) | 2011-11-29 | 2013-05-01 | 江苏德达医药科技有限公司 | 一种聚维酮碘眼用缓释滴眼液 |
| CN102988424A (zh) * | 2012-12-29 | 2013-03-27 | 潍坊富邦药业有限公司 | 一种加速动物伤口愈合、止痛生肌的喷雾剂及制备工艺 |
| JP6226997B2 (ja) * | 2013-02-15 | 2017-11-08 | 千寿製薬株式会社 | 亜鉛を含有するジフルプレドナートエマルション組成物 |
| DE102014000132A1 (de) * | 2014-01-13 | 2015-07-16 | Marco Bergmann | Verfahren und Vorrichtung zum Anordnen mehrerer Lebensmittel in wenigstens einem Unterteil einer Verpackung |
| EP3247365A4 (en) | 2015-01-20 | 2018-08-01 | Veloce BioPharma LLC | Novel iodophor composition and methods of use |
| JP6527596B2 (ja) * | 2015-04-24 | 2019-06-05 | エルジー イノテック カンパニー リミテッド | タッチウィンドウ |
| JP6255134B1 (ja) * | 2016-11-02 | 2017-12-27 | ヴェローチェ・バイオファーマ・エルエルシー | 耳炎の治療のための組成物および方法 |
| WO2019046844A1 (en) * | 2017-09-02 | 2019-03-07 | Iview Therapeutics, Inc. | PHARMACEUTICAL COMPOSITIONS FORMING IN SITU A GEL AND THEIR USES FOR SINUS DISEASES |
| JP2022151438A (ja) * | 2021-03-26 | 2022-10-07 | 均 石井 | 外耳炎と中耳炎と内耳炎の治療薬。 |
| WO2025144407A1 (en) * | 2023-12-28 | 2025-07-03 | Iview Therapeutics, Inc. | Methods for increasing stability of dilute povidone iodine |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69807281T2 (de) * | 1997-05-14 | 2003-04-17 | Mitsubishi Chemical Corp., Tokio/Tokyo | Difluprednat enthaltende Zusammensetzungen |
| AU2002333671B2 (en) * | 2001-09-21 | 2006-07-20 | Novartis Ag | Method of treating middle ear infections |
| CA2508762A1 (en) * | 2002-12-06 | 2004-06-24 | Arriva Pharmaceuticals, Inc. | Methods and compositions for treatment of otitis media |
| US20060057226A1 (en) * | 2004-09-16 | 2006-03-16 | Johnson John M | Red ear drops |
| CN101137359B (zh) * | 2005-03-10 | 2011-01-12 | 3M创新有限公司 | 治疗耳感染的方法 |
| US20060280809A1 (en) * | 2005-06-14 | 2006-12-14 | Leshchiner Adele K | Anti-infective iodine based compositions for otic and nasal use |
| US7767217B2 (en) | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
| US20080167281A1 (en) * | 2007-01-05 | 2008-07-10 | Preston David M | Combination Otic Formulation |
| US20080172032A1 (en) * | 2007-01-11 | 2008-07-17 | James Pitzer Gills | Method for preventing tissue damage associated with irrigation of tissue with an antimicrobial solution |
| WO2008137658A1 (en) * | 2007-05-03 | 2008-11-13 | Mayo Foundation For Medical Education And Research | Otitis externa |
| MX372536B (es) * | 2008-06-12 | 2020-03-23 | Takeda Pharmaceuticals Co | Povidona yodada, un conservador alternativo novedoso para composiciones oftalmicas. |
-
2009
- 2009-02-27 US US12/380,463 patent/US20090263345A1/en not_active Abandoned
-
2010
- 2010-02-24 CN CN201510833603.4A patent/CN105362286A/zh active Pending
- 2010-02-24 NZ NZ594884A patent/NZ594884A/en not_active IP Right Cessation
- 2010-02-24 CN CN2010800095228A patent/CN102333444A/zh active Pending
- 2010-02-24 KR KR1020117021777A patent/KR20110133479A/ko not_active Ceased
- 2010-02-24 WO PCT/US2010/025251 patent/WO2010099212A1/en not_active Ceased
- 2010-02-24 KR KR1020167025617A patent/KR20160112024A/ko not_active Ceased
- 2010-02-24 MX MX2011008920A patent/MX2011008920A/es unknown
- 2010-02-24 PE PE2015001315A patent/PE20151298A1/es unknown
- 2010-02-24 PE PE2011001555A patent/PE20120183A1/es not_active Application Discontinuation
- 2010-02-24 EP EP19211027.8A patent/EP3673736A1/en not_active Withdrawn
- 2010-02-24 AU AU2010218108A patent/AU2010218108B2/en not_active Ceased
- 2010-02-24 KR KR1020187003459A patent/KR20180017213A/ko not_active Ceased
- 2010-02-24 EP EP10746775.5A patent/EP2400842A4/en not_active Ceased
- 2010-02-24 JP JP2011552132A patent/JP5714512B2/ja not_active Expired - Fee Related
- 2010-02-24 BR BRPI1012230A patent/BRPI1012230A2/pt not_active Application Discontinuation
- 2010-02-24 CA CA2753964A patent/CA2753964C/en not_active Expired - Fee Related
- 2010-02-24 KR KR1020197019832A patent/KR20190100237A/ko not_active Ceased
-
2011
- 2011-08-26 CL CL2011002091A patent/CL2011002091A1/es unknown
- 2011-09-16 US US13/234,978 patent/US20120003174A1/en not_active Abandoned
- 2011-09-26 EC EC2011011354A patent/ECSP11011354A/es unknown
- 2011-09-26 CO CO11125604A patent/CO6450663A2/es not_active Application Discontinuation
-
2012
- 2012-05-08 US US13/466,763 patent/US20130089510A1/en not_active Abandoned
-
2014
- 2014-12-17 JP JP2014254897A patent/JP2015083589A/ja not_active Withdrawn
-
2016
- 2016-05-30 AU AU2016203574A patent/AU2016203574B2/en not_active Ceased
- 2016-10-03 JP JP2016195551A patent/JP2017031202A/ja active Pending
-
2017
- 2017-11-29 AU AU2017268575A patent/AU2017268575A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2400842A1 (en) | 2012-01-04 |
| CA2753964C (en) | 2019-03-12 |
| ECSP11011354A (es) | 2011-12-30 |
| CN105362286A (zh) | 2016-03-02 |
| CO6450663A2 (es) | 2012-05-31 |
| KR20180017213A (ko) | 2018-02-20 |
| CL2011002091A1 (es) | 2012-04-20 |
| JP2015083589A (ja) | 2015-04-30 |
| US20130089510A1 (en) | 2013-04-11 |
| EP2400842A4 (en) | 2013-08-28 |
| BRPI1012230A2 (pt) | 2017-11-07 |
| AU2010218108B2 (en) | 2016-07-07 |
| US20120003174A1 (en) | 2012-01-05 |
| CN102333444A (zh) | 2012-01-25 |
| AU2017268575A1 (en) | 2017-12-14 |
| JP5714512B2 (ja) | 2015-05-07 |
| NZ594884A (en) | 2014-02-28 |
| WO2010099212A1 (en) | 2010-09-02 |
| AU2016203574B2 (en) | 2017-08-31 |
| KR20110133479A (ko) | 2011-12-12 |
| JP2017031202A (ja) | 2017-02-09 |
| KR20190100237A (ko) | 2019-08-28 |
| EP3673736A1 (en) | 2020-07-01 |
| MX2011008920A (es) | 2011-09-09 |
| KR20160112024A (ko) | 2016-09-27 |
| AU2010218108A1 (en) | 2011-10-20 |
| US20090263345A1 (en) | 2009-10-22 |
| JP2012519175A (ja) | 2012-08-23 |
| CA2753964A1 (en) | 2010-09-02 |
| AU2016203574A1 (en) | 2016-06-16 |
| PE20120183A1 (es) | 2012-03-15 |
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