PE20151947A1 - Reduccion de la respuesta proinflamatoria - Google Patents
Reduccion de la respuesta proinflamatoriaInfo
- Publication number
- PE20151947A1 PE20151947A1 PE2015001982A PE2015001982A PE20151947A1 PE 20151947 A1 PE20151947 A1 PE 20151947A1 PE 2015001982 A PE2015001982 A PE 2015001982A PE 2015001982 A PE2015001982 A PE 2015001982A PE 20151947 A1 PE20151947 A1 PE 20151947A1
- Authority
- PE
- Peru
- Prior art keywords
- pro
- inflammatory response
- reduction
- composition
- inflammatory
- Prior art date
Links
- 230000007112 pro inflammatory response Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000000770 proinflammatory effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
La presente divulgacion proporciona un procedimiento para suprimir una respuesta proinflamatoria mediante la administracion de una composicion que comprende peptidos seleccionados a partir de un hidrolizado de caseina. Dicha composicion puede reducir los niveles de citoquinas proinflamatorias y puede ser un tratamiento para enfermedades inflamatorias, especialmente la diabetes tipo 1. Preferiblemente, el hidrolizado consiste en peptidos con un peso molecular mayor a 500 Da
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/838,539 US9352020B2 (en) | 2013-03-15 | 2013-03-15 | Reducing proinflammatory response |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20151947A1 true PE20151947A1 (es) | 2016-01-20 |
Family
ID=50391507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2015001982A PE20151947A1 (es) | 2013-03-15 | 2014-03-11 | Reduccion de la respuesta proinflamatoria |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9352020B2 (es) |
| EP (1) | EP2968437B1 (es) |
| CN (1) | CN105142658B (es) |
| AR (1) | AR095336A1 (es) |
| AU (1) | AU2014237027C1 (es) |
| BR (1) | BR112015018259A2 (es) |
| CA (1) | CA2905820A1 (es) |
| ES (1) | ES2821750T3 (es) |
| MX (1) | MX2015011938A (es) |
| MY (1) | MY177369A (es) |
| PE (1) | PE20151947A1 (es) |
| PH (1) | PH12015502102B1 (es) |
| RU (1) | RU2015139359A (es) |
| SG (1) | SG11201505693WA (es) |
| TW (1) | TW201505647A (es) |
| WO (1) | WO2014150571A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107708718B (zh) * | 2015-04-22 | 2022-01-11 | 西达-赛奈医疗中心 | 用于治疗2型糖尿病的肠内递送的苦味寡肽 |
| US20170020950A1 (en) * | 2015-07-23 | 2017-01-26 | Mead Johnson Nutrition Company | Methods for modulating kinases |
| CA3004722A1 (en) * | 2015-11-09 | 2017-05-18 | Mjn U.S. Holdings Llc | Nutritional compositions comprising lactobacillus rhamnosus gg, as well as dietary butyrate and/or a compound for stimulating formation of endogenous butyrate |
| US10034937B2 (en) | 2015-12-04 | 2018-07-31 | Mead Johnson Nutrition Company | Synergistic nutritional compositions and uses thereof |
| RU2659240C2 (ru) * | 2016-05-23 | 2018-06-29 | федеральное государственное бюджетное образовательное учреждение высшего образования "Кемеровский государственный университет" (КемГУ) | Способ получения функционального продукта питания для реабилитации онкологических больных |
| US20180160714A1 (en) * | 2016-12-12 | 2018-06-14 | Mead Johnson Nutrition Company | Nutritional compositions containing butyrate and uses thereof |
| EP3612570A4 (en) | 2017-04-17 | 2021-01-13 | The University of Chicago | POLYMERIC MATERIALS FOR THE ADMINISTRATION OF SHORT-CHAIN FATTY ACIDS TO THE INTESTINE FOR HUMAN HEALTH AND DISEASE TREATMENT APPLICATIONS |
| US20190208807A1 (en) * | 2018-01-05 | 2019-07-11 | Mead Johnson Nutrition Company | Nutritional compositions containing milk-derived peptides and uses thereof |
| CN108967557A (zh) * | 2018-09-29 | 2018-12-11 | 贝因美(杭州)食品研究院有限公司 | 一种婴儿配方食品及其制备方法 |
| CN110204595A (zh) * | 2019-06-04 | 2019-09-06 | 海普诺凯营养品有限公司 | 一种具有调节b淋巴细胞活性的羊乳酪蛋白水解肽及其制备方法 |
| GB2608587B (en) * | 2021-06-25 | 2025-01-01 | Mjn Us Holdings Llc | Use of extensively hydrolysed protein |
| CN114989247B (zh) * | 2022-04-27 | 2024-04-02 | 中南林业科技大学 | 一种牦牛奶渣抗缺氧或低氧、抗疲劳肽及其制备方法和应用 |
| CN117384270B (zh) * | 2023-10-13 | 2024-07-16 | 华南理工大学 | 一种酪蛋白源dpp-iv抑制六肽及其制备方法与应用 |
| WO2026003044A1 (en) * | 2024-06-25 | 2026-01-02 | Ntd Labs, S.L. | Casein hydrolysate for treating crohn's disease |
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-
2013
- 2013-03-15 US US13/838,539 patent/US9352020B2/en active Active
-
2014
- 2014-03-11 SG SG11201505693WA patent/SG11201505693WA/en unknown
- 2014-03-11 MY MYPI2015702447A patent/MY177369A/en unknown
- 2014-03-11 MX MX2015011938A patent/MX2015011938A/es unknown
- 2014-03-11 EP EP14714100.6A patent/EP2968437B1/en active Active
- 2014-03-11 CN CN201480015639.5A patent/CN105142658B/zh active Active
- 2014-03-11 WO PCT/US2014/023637 patent/WO2014150571A1/en not_active Ceased
- 2014-03-11 CA CA2905820A patent/CA2905820A1/en not_active Abandoned
- 2014-03-11 ES ES14714100T patent/ES2821750T3/es active Active
- 2014-03-11 AU AU2014237027A patent/AU2014237027C1/en not_active Ceased
- 2014-03-11 RU RU2015139359A patent/RU2015139359A/ru unknown
- 2014-03-11 PE PE2015001982A patent/PE20151947A1/es not_active Application Discontinuation
- 2014-03-11 BR BR112015018259A patent/BR112015018259A2/pt not_active IP Right Cessation
- 2014-03-14 TW TW103109610A patent/TW201505647A/zh unknown
- 2014-03-14 AR ARP140101039A patent/AR095336A1/es unknown
-
2015
- 2015-09-14 PH PH12015502102A patent/PH12015502102B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2968437A1 (en) | 2016-01-20 |
| AU2014237027B2 (en) | 2019-02-28 |
| HK1216995A1 (zh) | 2016-12-16 |
| US9352020B2 (en) | 2016-05-31 |
| PH12015502102B1 (en) | 2021-06-23 |
| AU2014237027A1 (en) | 2015-08-13 |
| WO2014150571A1 (en) | 2014-09-25 |
| CA2905820A1 (en) | 2014-09-25 |
| TW201505647A (zh) | 2015-02-16 |
| CN105142658A (zh) | 2015-12-09 |
| AR095336A1 (es) | 2015-10-07 |
| MX2015011938A (es) | 2015-12-01 |
| NZ710033A (en) | 2020-09-25 |
| CN105142658B (zh) | 2018-10-23 |
| EP2968437B1 (en) | 2020-07-29 |
| RU2015139359A (ru) | 2017-04-24 |
| ES2821750T3 (es) | 2021-04-27 |
| SG11201505693WA (en) | 2015-08-28 |
| AU2014237027C1 (en) | 2019-06-06 |
| US20140271554A1 (en) | 2014-09-18 |
| PH12015502102A1 (en) | 2016-01-11 |
| MY177369A (en) | 2020-09-14 |
| BR112015018259A2 (pt) | 2017-08-22 |
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