PE20141607A1 - Compuestos heterociclicos, medicamentos que los contienen, uso de aquellos y procesos para su preparacion - Google Patents
Compuestos heterociclicos, medicamentos que los contienen, uso de aquellos y procesos para su preparacionInfo
- Publication number
- PE20141607A1 PE20141607A1 PE2014000641A PE2014000641A PE20141607A1 PE 20141607 A1 PE20141607 A1 PE 20141607A1 PE 2014000641 A PE2014000641 A PE 2014000641A PE 2014000641 A PE2014000641 A PE 2014000641A PE 20141607 A1 PE20141607 A1 PE 20141607A1
- Authority
- PE
- Peru
- Prior art keywords
- compounds
- drugs
- contain
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
SE REFIERE A COMPUESTOS DE FORMULA (I), EN DONDE: A ES UN ENLACE, -CH2-, -CH2CH2-, -CH2CH2CH2-, ENTRE OTROS; B ES -CH2-, ENTRE OTROS; D Y E SON INDEPENDIENTEMENTE UN ENLACE O -CH2-; F ES ARILO O HETEROARILO; G ES (g.1), ENTRE OTROS; R1 ES H, C1-6-ALQUILO, HETEROCICLIL-CO- OPCIONALMENTE SUSTITUIDO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: TER-BUTILESTER DEL ACIDO 4-[N�-(3,5-DIAMINO-6-CLORO-PIRAZIN-2-CARBONIL)-GUANIDINOMETIL]-4-FENETIL-PIPERIDIN-1-CARBOXILICO; N-(3,5-DIAMINO-6-CLORO-PIRAZIN-2-CARBONIL)-N�-(4-FENETIL-PIPERIDIN-4-ILMETIL-GUANIDINA; ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS TIENEN UN EFECTO INHIBIDOR EN LOS CANALES DE SODIO EPITELIALES, SIENDO UTILES PARA EL TRATAMIENTO DE BRONQUITIS CRONICA, ASMA, FIBROSIS QUISTICA, EDEMA PULMONAR, SINUSITIS CRONICA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11187553 | 2011-11-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20141607A1 true PE20141607A1 (es) | 2014-11-23 |
Family
ID=47073464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2014000641A PE20141607A1 (es) | 2011-11-02 | 2012-10-29 | Compuestos heterociclicos, medicamentos que los contienen, uso de aquellos y procesos para su preparacion |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US8759349B2 (es) |
| EP (1) | EP2773633B1 (es) |
| JP (1) | JP6091513B2 (es) |
| KR (1) | KR102006612B1 (es) |
| CN (2) | CN104024244B (es) |
| AP (1) | AP2014007670A0 (es) |
| AU (1) | AU2012331274B2 (es) |
| BR (1) | BR112014010583A2 (es) |
| CA (1) | CA2854217C (es) |
| CL (1) | CL2014001047A1 (es) |
| CO (1) | CO6940429A2 (es) |
| CY (1) | CY1120974T1 (es) |
| DK (1) | DK2773633T3 (es) |
| EA (1) | EA025158B9 (es) |
| EC (1) | ECSP14001929A (es) |
| ES (1) | ES2645744T3 (es) |
| GE (2) | GEP20186880B (es) |
| HR (1) | HRP20171614T1 (es) |
| HU (1) | HUE034929T2 (es) |
| IL (1) | IL232035A (es) |
| LT (1) | LT2773633T (es) |
| ME (1) | ME02905B (es) |
| MX (1) | MX348522B (es) |
| NO (1) | NO2773633T3 (es) |
| PE (1) | PE20141607A1 (es) |
| PH (1) | PH12014500970B1 (es) |
| PL (1) | PL2773633T3 (es) |
| PT (1) | PT2773633T (es) |
| RS (1) | RS56498B1 (es) |
| SG (1) | SG11201401907TA (es) |
| SI (1) | SI2773633T1 (es) |
| TN (1) | TN2014000180A1 (es) |
| UA (1) | UA115868C2 (es) |
| WO (1) | WO2013064450A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1993360T3 (en) | 2005-12-28 | 2017-05-22 | Vertex Pharma | SOLID FORMS OF N- [2,4-BIS (1,1-DIMETHYLETHYL) -5-HYDROXYPHENYL] -1,4-DIHYDRO-4-OXOQUINOLIN-3-CARBOXAMIDE |
| ES2645744T3 (es) * | 2011-11-02 | 2017-12-07 | Boehringer Ingelheim International Gmbh | Compuestos heterocíclicos, medicamentos que contienen dichos compuestos, uso de los mismos y procedimientos para la preparación de los mismos |
| KR20160054460A (ko) * | 2013-07-02 | 2016-05-16 | 더 캘리포니아 인스티튜트 포 바이오메디칼 리써치 | 낭성 섬유증의 치료를 위한 화합물 |
| EP3019492B1 (en) | 2013-07-08 | 2017-09-06 | Boehringer Ingelheim International GmbH | Amiloride-type compounds as inhibitors in epithelial sodium channels for the treatment of diseases of the lungs and airways |
| CN107250113B (zh) | 2014-10-07 | 2019-03-29 | 弗特克斯药品有限公司 | 囊性纤维化跨膜传导调节蛋白的调节剂的共晶 |
| TWI664166B (zh) | 2014-10-24 | 2019-07-01 | 日商小野藥品工業股份有限公司 | Ｋｃｎｑ２至５通道活化劑 |
| WO2016112120A1 (en) * | 2015-01-07 | 2016-07-14 | The California Institute For Biomedical Research | Compounds for treatment of cystic fibrosis |
| GB201610854D0 (en) | 2016-06-21 | 2016-08-03 | Entpr Therapeutics Ltd | Compounds |
| GB201619694D0 (en) | 2016-11-22 | 2017-01-04 | Entpr Therapeutics Ltd | Compounds |
| GB201717051D0 (en) | 2017-10-17 | 2017-11-29 | Enterprise Therapeutics Ltd | Compounds |
| GB201808093D0 (en) | 2018-05-18 | 2018-07-04 | Enterprise Therapeutics Ltd | Compounds |
| KR20230093251A (ko) | 2020-09-10 | 2023-06-27 | 프리시릭스 엔.브이. | Fap에 대한 항체 단편 |
| CN112107580A (zh) * | 2020-09-29 | 2020-12-22 | 北京鑫开元医药科技有限公司 | 一种脾酪氨酸激酶抑制剂的制剂组合物及其制备方法 |
| WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
| KR20250034289A (ko) | 2022-05-02 | 2025-03-11 | 프리시릭스 엔.브이. | 사전 표적화 |
| WO2024243025A1 (en) * | 2023-05-19 | 2024-11-28 | Ikena Oncology, Inc. | Naphthyl-substituted pyrido[4,3-d]pyrimidines and related compounds and their use in treating medical conditions |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6812003A (es) | 1967-09-07 | 1969-03-11 | ||
| US3953476A (en) | 1971-12-27 | 1976-04-27 | Merck & Co., Inc. | 3-Amino-5-sulfonylbenzoic acids |
| ES2304352T3 (es) | 1999-07-19 | 2008-10-16 | University Of North Carolina At Chapel Hill | Compuestos farmacologicamente activos con dos principios activos unidos covalentemente (bloqueante de los canales de sodio/agonista del receptor p2y2) para el tratamiento de superficies mucosas. |
| JP2003520042A (ja) | 2000-01-24 | 2003-07-02 | アイシス・ファーマシューティカルス・インコーポレーテッド | 誘導性一酸化窒素シンターゼ発現のアンチセンスモジュレーション |
| KR20070059063A (ko) | 2004-08-18 | 2007-06-11 | 마이클 알 존슨. | 지방족 아미드 및 에스테르 피라지노일구아니딘 나트륨채널 차단제 |
| GB0526244D0 (en) * | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| AU2006346492A1 (en) * | 2006-07-24 | 2008-01-31 | International Stem Cell Corporation | Synthetic cornea from retinal stem cells |
| CN101687851B (zh) * | 2007-05-07 | 2013-02-27 | 诺瓦提斯公司 | 有机化合物 |
| KR101578235B1 (ko) | 2007-12-10 | 2015-12-16 | 노파르티스 아게 | 유기 화합물 |
| CN102015662A (zh) * | 2008-05-13 | 2011-04-13 | 诺瓦提斯公司 | 3,5-二氨基-6-氯-吡嗪-2-甲酸衍生物和它们作为上皮钠通道阻断剂用于治疗气道疾病的用途 |
| US8236808B2 (en) | 2008-06-10 | 2012-08-07 | Novartis Ag | Pyrazine derivatives as ENAC blockers |
| US9050339B2 (en) | 2010-09-17 | 2015-06-09 | Novartis Ag | Pyrazine derivatives as ENaC blockers |
| US8372845B2 (en) | 2010-09-17 | 2013-02-12 | Novartis Ag | Pyrazine derivatives as enac blockers |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| HUE032851T2 (en) | 2011-06-27 | 2017-11-28 | Parion Sciences Inc | A chemically and metabolically stable dipeptide having strong sodium channel blocking activity |
| ES2645744T3 (es) * | 2011-11-02 | 2017-12-07 | Boehringer Ingelheim International Gmbh | Compuestos heterocíclicos, medicamentos que contienen dichos compuestos, uso de los mismos y procedimientos para la preparación de los mismos |
| EP2773624A1 (en) | 2011-11-02 | 2014-09-10 | Boehringer Ingelheim International GmbH | Novel process for the preparation of acylguanidines and acylthioureas |
-
2012
- 2012-10-29 ES ES12777930.4T patent/ES2645744T3/es active Active
- 2012-10-29 LT LTEP12777930.4T patent/LT2773633T/lt unknown
- 2012-10-29 PT PT127779304T patent/PT2773633T/pt unknown
- 2012-10-29 PL PL12777930T patent/PL2773633T3/pl unknown
- 2012-10-29 HU HUE12777930A patent/HUE034929T2/en unknown
- 2012-10-29 JP JP2014539297A patent/JP6091513B2/ja active Active
- 2012-10-29 AP AP2014007670A patent/AP2014007670A0/xx unknown
- 2012-10-29 KR KR1020147012186A patent/KR102006612B1/ko not_active Expired - Fee Related
- 2012-10-29 GE GEAP201213485A patent/GEP20186880B/en unknown
- 2012-10-29 PE PE2014000641A patent/PE20141607A1/es active IP Right Grant
- 2012-10-29 SG SG11201401907TA patent/SG11201401907TA/en unknown
- 2012-10-29 AU AU2012331274A patent/AU2012331274B2/en not_active Ceased
- 2012-10-29 CA CA2854217A patent/CA2854217C/en not_active Expired - Fee Related
- 2012-10-29 CN CN201280065806.8A patent/CN104024244B/zh active Active
- 2012-10-29 UA UAA201405764A patent/UA115868C2/uk unknown
- 2012-10-29 NO NO12777930A patent/NO2773633T3/no unknown
- 2012-10-29 EA EA201400521A patent/EA025158B9/ru not_active IP Right Cessation
- 2012-10-29 EP EP12777930.4A patent/EP2773633B1/en active Active
- 2012-10-29 HR HRP20171614TT patent/HRP20171614T1/hr unknown
- 2012-10-29 DK DK12777930.4T patent/DK2773633T3/da active
- 2012-10-29 RS RS20171069A patent/RS56498B1/sr unknown
- 2012-10-29 MX MX2014005166A patent/MX348522B/es active IP Right Grant
- 2012-10-29 WO PCT/EP2012/071352 patent/WO2013064450A1/en not_active Ceased
- 2012-10-29 PH PH1/2014/500970A patent/PH12014500970B1/en unknown
- 2012-10-29 GE GEAP201813485A patent/GEAP201813485A/en unknown
- 2012-10-29 CN CN201610685839.2A patent/CN106279110B/zh active Active
- 2012-10-29 ME MEP-2017-247A patent/ME02905B/me unknown
- 2012-10-29 SI SI201231100T patent/SI2773633T1/sl unknown
- 2012-10-29 US US13/662,791 patent/US8759349B2/en active Active
- 2012-10-29 BR BR112014010583A patent/BR112014010583A2/pt active Search and Examination
-
2014
- 2014-04-09 IL IL232035A patent/IL232035A/en not_active IP Right Cessation
- 2014-04-24 CL CL2014001047A patent/CL2014001047A1/es unknown
- 2014-04-28 TN TNP2014000180A patent/TN2014000180A1/en unknown
- 2014-04-28 US US14/263,344 patent/US20140228374A1/en not_active Abandoned
- 2014-04-30 CO CO14092699A patent/CO6940429A2/es unknown
- 2014-05-26 EC ECIEPI20141929A patent/ECSP14001929A/es unknown
-
2015
- 2015-08-05 US US14/818,478 patent/US9920035B2/en active Active
-
2017
- 2017-10-30 CY CY171101128T patent/CY1120974T1/el unknown
- 2017-12-13 US US15/840,309 patent/US20180194747A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20141607A1 (es) | Compuestos heterociclicos, medicamentos que los contienen, uso de aquellos y procesos para su preparacion | |
| EA201492281A1 (ru) | Соединения n-арилтриазола в качестве антагонистов рецепторов лизофосфатидной кислоты (lpar) | |
| EA201492285A1 (ru) | Соединения n-алкилтриазола в качестве антагонистов лизофосфатидной кислоты (lpar) | |
| UY35288A (es) | Piridonamidas como moduladores de canales de sodio | |
| DOP2012000310A (es) | Morfolinopirimidinas y su uso en terapia | |
| EA201990388A1 (ru) | Пиперидиновые модуляторы рецепторов cxcr7 | |
| UY32156A (es) | Derivados sustituidos de la n2 - [1-(5 - fluoropirimidin -2-il) etil] - n4 - (1-metil - 1h-imidazol - 4 - il)) - pirimidina - 2,4 - diaminas y sus sales farmacéuticamente aceptables, proceso de preparación, composiciones conteniéndolos y aplicaciones. | |
| UY35300A (es) | Formulación de combinación de dos compuestos antivirales | |
| NI201400031A (es) | Derivados de ( 4 - fenilimidazol - 2 - il ) etilamina útiles como moduladores de canal de sodio | |
| BR112014009087A2 (pt) | formulações de etanercept estabilizadas com xilitol | |
| CO6690768A2 (es) | Derivados de triazina-oxadiazoles, útiles como inhibidores de los canales de sodio navi.7 | |
| EA201891179A1 (ru) | N-замещенные индольные производные в качестве модуляторов pge2 рецепторов | |
| BR112015023399A8 (pt) | inibidores de hdac, seu uso e composição farmacêutica | |
| EA201490471A1 (ru) | Пиридазиноновые соединения и их применение в качестве ингибиторов daao | |
| PE20150224A1 (es) | Inhibidores del nampt | |
| UY35275A (es) | Derivados de aminopirazina | |
| EA201490152A1 (ru) | Антагонисты trpm8 и их применение при лечении | |
| EA201291217A1 (ru) | ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ПРОИЗВОДНЫЕ 1-(β-D-ГЛЮКОПИРАНОЗИЛ)-2-ТИЕНИЛМЕТИЛБЕНЗОЛА КАК ИНГИБИТОРЫ НЗПГ | |
| EA201492283A1 (ru) | Замещенные соединения пиразола в качестве антагонистов рецепторов лизофосфатидной кислоты (lpar) | |
| CU20150084A7 (es) | Derivados del ácido 4-((1,1) bisfenil -4-il)-3-(3-fosfonopropanamido)butanoico,activo como inhibidores de nep(endopeptidasa neutral) | |
| UY35535A (es) | ?Derivados de fenil sulfonamidas?. | |
| MX384392B (es) | Moduladores heterocíclicos de la síntesis de lípidos para su uso contra el cáncer e infecciones virales. | |
| MX379859B (es) | Compuestos de indolinona y su uso en el tratamiento de enfermedades fibróticas. | |
| EA201890331A1 (ru) | Пиридинондикарбоксамиды для применения в качестве ингибиторов бромодомена | |
| EA201992679A1 (ru) | N-замещенные индольные производные |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |