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PE20130245A1 - Composicion de hidrogel de dexibuprofeno transdermico - Google Patents

Composicion de hidrogel de dexibuprofeno transdermico

Info

Publication number
PE20130245A1
PE20130245A1 PE2012000848A PE2012000848A PE20130245A1 PE 20130245 A1 PE20130245 A1 PE 20130245A1 PE 2012000848 A PE2012000848 A PE 2012000848A PE 2012000848 A PE2012000848 A PE 2012000848A PE 20130245 A1 PE20130245 A1 PE 20130245A1
Authority
PE
Peru
Prior art keywords
composition
sodium
hydrogel
dexibuprophen
transdermal
Prior art date
Application number
PE2012000848A
Other languages
English (en)
Inventor
Jeffrey Stuart Bergman
Sampathkumar Devarajan
Selvakumar Ramalingam
Anandsenthil Vel Palanisamy
Original Assignee
Shasun Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shasun Pharmaceuticals Ltd filed Critical Shasun Pharmaceuticals Ltd
Publication of PE20130245A1 publication Critical patent/PE20130245A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMPOSICION DE HIDROGEL TRANSDERMICO NO ALCOHOLICO QUE COMPRENDE: DEXIBUPROFENO [ACIDO (S)-2-(4-ISOBUTILFENIL)PROPIONICO]; ESENCIALMENTE UNO O MAS MODIFICADORES DE pH TAL COMO HIDROXIDO DE SODIO, ACIDO CITRICO, CITRATO DE SODIO, TRIETANOLAMINA Y DIETANOLAMINA; ANTIOXIDANTES TAL COMO BENZOATO DE SODIO, METABISULFITO DE SODIO, HIDROXITOLUENO BUTILADO E HIDROXANISOL BUTILADO; DISOLVENTES MISCIBLES EN AGUA TAL COMO POLIETILENGLICOL, PROPILENGLICOL Y GLICERINA; ADEMAS COMPRENDE UNO O MAS POLIMEROS GELIFICANTES TAL COMO HIDROXIPROPILMETILCELULOSA (HPMC), PECTINA, GOMA GUAR, POLIACRILAMIDA, ENTRE OTROS, TENSIOACTIVOS, AGENTES ANTIESPUMANTES, AGENTES QUELANTES, CONSERVANTES, ENTRE OTROS. REFERIDO ADEMAS A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION PUEDE SER TRANSPARENTE O TRANSLUCIDA U OPACA
PE2012000848A 2009-12-16 2010-12-09 Composicion de hidrogel de dexibuprofeno transdermico PE20130245A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3121CH2009 2009-12-16

Publications (1)

Publication Number Publication Date
PE20130245A1 true PE20130245A1 (es) 2013-03-08

Family

ID=54200209

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000848A PE20130245A1 (es) 2009-12-16 2010-12-09 Composicion de hidrogel de dexibuprofeno transdermico

Country Status (15)

Country Link
US (2) US20120259018A1 (es)
EP (1) EP2512446B1 (es)
JP (1) JP2013514347A (es)
KR (1) KR101884951B1 (es)
CN (1) CN102665681A (es)
AU (1) AU2010331761B2 (es)
BR (1) BR112012014558B8 (es)
CA (1) CA2784827C (es)
DK (1) DK2512446T3 (es)
ES (1) ES2541483T3 (es)
MX (1) MX352187B (es)
PE (1) PE20130245A1 (es)
PL (1) PL2512446T3 (es)
RU (1) RU2012129527A (es)
WO (1) WO2011073998A1 (es)

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Also Published As

Publication number Publication date
RU2012129527A (ru) 2014-01-27
BR112012014558B1 (pt) 2021-02-02
US20120259018A1 (en) 2012-10-11
KR20120092700A (ko) 2012-08-21
MX352187B (es) 2017-11-13
CN102665681A (zh) 2012-09-12
BR112012014558B8 (pt) 2021-05-25
BR112012014558A8 (pt) 2018-04-10
AU2010331761A1 (en) 2012-07-12
CA2784827A1 (en) 2011-06-23
US10085939B2 (en) 2018-10-02
WO2011073998A1 (en) 2011-06-23
ES2541483T3 (es) 2015-07-21
US20150342879A1 (en) 2015-12-03
CA2784827C (en) 2018-10-23
MX2012007062A (es) 2012-10-03
EP2512446A4 (en) 2012-10-24
EP2512446A1 (en) 2012-10-24
EP2512446B1 (en) 2015-04-08
KR101884951B1 (ko) 2018-08-02
PL2512446T3 (pl) 2015-08-31
BR112012014558A2 (pt) 2017-12-19
AU2010331761B2 (en) 2015-09-24
DK2512446T3 (en) 2015-06-29
JP2013514347A (ja) 2013-04-25

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