PE20120326A1 - Formulaciones farmaceuticas para reducir la proliferacion y viabilidad de los agentes microbianos - Google Patents
Formulaciones farmaceuticas para reducir la proliferacion y viabilidad de los agentes microbianosInfo
- Publication number
- PE20120326A1 PE20120326A1 PE2011001447A PE2011001447A PE20120326A1 PE 20120326 A1 PE20120326 A1 PE 20120326A1 PE 2011001447 A PE2011001447 A PE 2011001447A PE 2011001447 A PE2011001447 A PE 2011001447A PE 20120326 A1 PE20120326 A1 PE 20120326A1
- Authority
- PE
- Peru
- Prior art keywords
- agent
- surfactant
- viability
- proliferation
- reduce
- Prior art date
Links
- 230000035755 proliferation Effects 0.000 title abstract 2
- 230000035899 viability Effects 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 239000004094 surface-active agent Substances 0.000 abstract 4
- 150000003904 phospholipids Chemical class 0.000 abstract 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 239000004599 antimicrobial Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 229960004884 fluconazole Drugs 0.000 abstract 1
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 abstract 1
- 229960002722 terbinafine Drugs 0.000 abstract 1
- 229960004740 voriconazole Drugs 0.000 abstract 1
- BCEHBSKCWLPMDN-MGPLVRAMSA-N voriconazole Chemical compound C1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=NC=C1F BCEHBSKCWLPMDN-MGPLVRAMSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
REFERIDA A UNA FORMULACION ANTIMICROBIANA QUE COMPRENDE UN AGENTE ANTIMICOTICO O ANTIBACTERIANO, UN FOSFOLIPIDO Y UN SURFACTANTE, DONDE EL AGENTE ANTIMICOTICO ES VORICONAZOL, TERBINAFINA O FLUCONAZOL, EL AGENTE ANTIBACTERIANO ES UN ANTIBIOTICO TAL COMO ISONIAZIDA, ETAMBUTOL, PIRAZINAMIDA, TETRACICLINA, ENTRE OTROS, EL FOSFOLIPIDO ES FOSFATIDILCOLINA Y EL SURFACTANTE ES UN SURFACTANTE NO IONICO. LA PROPORCION MOLAR DE FOSFOLIPIDO A SURFACTANTE (MOL DE LIPIDO/MOL DE SURFACTANTE) ES DE 1:2 A 10:1. DICHA FORMULACION ES UTIL EN LA REDUCCION DE LA PROLIFERACION O VIABILIDAD DE UN AGENTE MICROBIANO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15028809P | 2009-02-05 | 2009-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20120326A1 true PE20120326A1 (es) | 2012-04-20 |
Family
ID=41460484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011001447A PE20120326A1 (es) | 2009-02-05 | 2009-07-23 | Formulaciones farmaceuticas para reducir la proliferacion y viabilidad de los agentes microbianos |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20100197621A1 (es) |
| EP (1) | EP2393480A1 (es) |
| JP (1) | JP2012516889A (es) |
| KR (1) | KR20110128283A (es) |
| CN (1) | CN102368998A (es) |
| AU (1) | AU2009339445A1 (es) |
| BR (1) | BRPI0924302A2 (es) |
| CA (1) | CA2751412A1 (es) |
| CO (1) | CO6410285A2 (es) |
| CR (1) | CR20110409A (es) |
| EC (1) | ECSP11011246A (es) |
| IL (1) | IL214331A0 (es) |
| MX (1) | MX2011008204A (es) |
| NI (1) | NI201100152A (es) |
| PE (1) | PE20120326A1 (es) |
| RU (1) | RU2011136624A (es) |
| SG (1) | SG173183A1 (es) |
| WO (1) | WO2010090654A1 (es) |
| ZA (1) | ZA201105758B (es) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090175810A1 (en) | 2008-01-03 | 2009-07-09 | Gareth Winckle | Compositions and methods for treating diseases of the nail |
| DE112010003355T5 (de) | 2009-08-21 | 2012-07-12 | Targeted Delivery Technologies Ltd. | Veskuläre Formulierungen |
| EP2571869B1 (en) | 2010-05-19 | 2015-09-23 | Sandoz AG | Purification of posaconazole and posaconazole intermediates |
| CN102892762B (zh) | 2010-05-19 | 2016-04-20 | 桑多斯股份公司 | 制备泊沙康唑中间体 |
| EP2571871B1 (en) | 2010-05-19 | 2017-06-21 | Sandoz AG | Process for the preparation of chiral triazolones |
| CN102892750B (zh) | 2010-05-19 | 2016-03-02 | 桑多斯股份公司 | 制备手性酰肼的方法 |
| US8039494B1 (en) | 2010-07-08 | 2011-10-18 | Dow Pharmaceutical Sciences, Inc. | Compositions and methods for treating diseases of the nail |
| RU2618456C2 (ru) | 2010-12-16 | 2017-05-03 | Плэтформ Брайтворкс Ту, Лтд | Фармацевтические препараты азолов для парентерального введения и способы их получения и применения для лечения заболеваний, чувствительных к азольным соединениям |
| EP2685820A4 (en) * | 2011-03-15 | 2014-08-27 | Thompson Cooper Lab Llc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF INFECTIONS |
| DE112012001386T5 (de) * | 2011-03-21 | 2013-12-19 | Gregor Cevc | Optimierte Präparate von sehr anpassungsfähigen Aggregaten |
| MX360638B (es) | 2011-04-28 | 2018-11-12 | Univ Texas | Formulaciones parenterales mejoradas de agentes farmacéuticos lipofílicos y métodos para prepararlos y usarlos. |
| WO2012172015A1 (en) | 2011-06-16 | 2012-12-20 | Sandoz Ag | Process for the preparation of a chiral compound |
| WO2013043830A1 (en) * | 2011-09-20 | 2013-03-28 | Molecular Express, Inc. | Nanoparticle formulations of poorly soluble compounds |
| KR101350442B1 (ko) * | 2011-10-12 | 2014-01-15 | 김동진 | 클로르헥시딘을 함유하는 안정한 수용성 살균방부제 조성물 |
| WO2013057208A1 (en) | 2011-10-18 | 2013-04-25 | Targeted Delivery Technologies Limited | Compositions and methods for reducing the proliferation and viability of microbial agents |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| CN102659734B (zh) * | 2012-04-28 | 2014-07-16 | 山东大学 | 一种三烯抗生素的制备方法 |
| CN104379132A (zh) * | 2012-06-14 | 2015-02-25 | 桑多斯股份公司 | 包含结晶泊沙康唑的药物组合物 |
| US20150250808A1 (en) * | 2012-10-15 | 2015-09-10 | Vojo P. Deretic | Treatment of autophagy-based disorders and related pharmaceutical compositions, diagnostic and screening assays and kits |
| US8815952B1 (en) | 2013-03-15 | 2014-08-26 | Carnell & Herzog, LLC | Chlorhexadine antiseptic |
| JP6206907B2 (ja) * | 2013-07-16 | 2017-10-04 | 株式会社ゲノム創薬研究所 | 抗菌活性促進剤及び該抗菌活性促進剤を含有する感染症治療薬 |
| JP6516759B2 (ja) * | 2013-10-03 | 2019-05-22 | ダウ ファーマシューティカル サイエンシーズ,インコーポレイティド | 安定化エフィナコナゾール組成物 |
| KR102612453B1 (ko) | 2013-11-22 | 2023-12-08 | 다우 파마슈티컬 사이언시즈, 인코포레이티드 | 항감염 방법,조성물,및 장치 |
| CN103690543B (zh) * | 2013-12-24 | 2015-09-09 | 广西医科大学 | 杀死烟曲霉菌的组合物及方法 |
| PT3316857T (pt) | 2015-06-30 | 2021-11-03 | Sequessome Tech Holdings Limited | Composições multifásicas |
| CN106546668A (zh) * | 2015-09-22 | 2017-03-29 | 陕西合成药业股份有限公司 | 一种分离福司氟康唑或其药用盐有关物质的hplc方法 |
| CN106890167A (zh) * | 2015-12-17 | 2017-06-27 | 中国科学院上海巴斯德研究所 | 一种具有抗结核活性的化合物及其应用 |
| WO2017112567A1 (en) * | 2015-12-22 | 2017-06-29 | 3M Innovative Properties Company | Methods for spore removal |
| WO2017188692A1 (ko) * | 2016-04-25 | 2017-11-02 | 경북대학교 산학협력단 | 7,10-에폭시옥타데카-7,9-다이에노산을 유효성분으로 포함하는 항균 조성물 |
| KR101749687B1 (ko) | 2016-04-25 | 2017-06-21 | 경북대학교 산학협력단 | 7,10-에폭시옥타데카-7,9-다이에노산을 유효성분으로 포함하는 항균 조성물 |
| KR101792239B1 (ko) | 2016-11-01 | 2017-10-31 | 경북대학교 산학협력단 | 7,10-에폭시옥타데카-7,9-다이에노산 및 항생제를 유효성분으로 포함하는 항균 조성물 |
| CN107184551B (zh) * | 2017-06-09 | 2020-09-01 | 甘肃新天马制药股份有限公司 | 一种利拉萘酯双粒径分布乳剂及其制备方法 |
| EP3746124A4 (en) | 2018-01-30 | 2021-10-27 | Foghorn Therapeutics Inc. | COMPOUNDS AND THEIR USES |
| US12509453B2 (en) | 2019-01-29 | 2025-12-30 | Foghorn Therapeutics Inc. | BRM/BRG1 inhibitors and uses thereof |
| MX2022009309A (es) | 2020-01-29 | 2022-08-22 | Foghorn Therapeutics Inc | Compuestos y usos de los mismos. |
| US12383555B2 (en) | 2020-05-20 | 2025-08-12 | Foghorn Therapeutics Inc. | Methods of treating cancers |
| CN111658610B (zh) * | 2020-07-31 | 2022-05-24 | 上海方予健康医药科技有限公司 | 一种供雾化器用的三氮唑类抗真菌药物的混悬液 |
| CN112791048B (zh) * | 2020-12-31 | 2023-01-17 | 海南海神同洲制药有限公司 | 一种硝酸舍他康唑栓及其制备方法 |
| CN112931213B (zh) * | 2021-03-29 | 2022-05-27 | 东北林业大学 | 一种杨树外植体脱毒试剂、脱毒方法及应用 |
| CN114432297B (zh) * | 2022-02-07 | 2022-10-11 | 中国人民解放军军事科学院军事医学研究院 | Zaragozic acid A在产气荚膜梭菌Epsilon毒素中毒救治中的应用 |
| CN115644062B (zh) * | 2022-11-03 | 2023-11-17 | 天津科润农业科技股份有限公司 | 一种提高难出胚大白菜胚诱导率的培养基及其方法 |
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| WO2024216136A1 (en) * | 2023-04-13 | 2024-10-17 | Foghorn Therapeutics Inc. | Combination therapy for the treatment of hematological cancers |
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| JPS6348214A (ja) * | 1986-08-18 | 1988-02-29 | Morishita Seiyaku Kk | 1−〔2−(2,4−ジクロロフエニル)−3−メチル−1−ペンテニル〕−1h−イミダゾ−ルを含有する水中油型脂肪乳剤 |
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| GB9111611D0 (en) * | 1991-05-30 | 1991-07-24 | Sandoz Ltd | Liposomes |
| US5536729A (en) * | 1993-09-30 | 1996-07-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
| DE4336434A1 (de) * | 1993-10-26 | 1995-04-27 | Hoechst Ag | Pharmazeutische Zubereitung für die parenterale, enterale und dermale Verabreichung von praktisch unlöslichen Arzneistoffen und Verfahren zu ihrer Herstellung |
| AU3257397A (en) * | 1996-06-07 | 1998-01-07 | Gist-Brocades B.V. | Antifungal compositions |
| EP0872229A1 (en) * | 1997-04-14 | 1998-10-21 | Janssen Pharmaceutica N.V. | Compositions containing an antifungal and a phospholipid |
| WO1999061001A1 (en) * | 1998-05-29 | 1999-12-02 | Rtp Pharma Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
| US20030215493A1 (en) * | 2002-04-30 | 2003-11-20 | Patel Pravin M. | Composition and method for dermatological treatment |
| US6846837B2 (en) * | 2002-06-21 | 2005-01-25 | Howard I. Maibach | Topical administration of basic antifungal compositions to treat fungal infections of the nails |
| US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| MX2007002462A (es) * | 2004-09-03 | 2007-10-10 | Piedmont Pharmaceuticals Llc | Metodo para el tratamiento de transmembrana y prevencion de la otitis media. |
| US8633191B2 (en) * | 2004-09-21 | 2014-01-21 | Stephen C. Perry | Anti-microbial and anti-fungal shampoo for mammals especially humans and dogs |
| US20060078580A1 (en) * | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
| US20060222716A1 (en) * | 2005-04-01 | 2006-10-05 | Joseph Schwarz | Colloidal solid lipid vehicle for pharmaceutical use |
| CN101273971A (zh) * | 2008-05-09 | 2008-10-01 | 绍兴文理学院 | 抗真菌药物的醇质体制剂及其制备方法 |
| AU2009275230A1 (en) * | 2008-07-23 | 2010-01-28 | Targeted Delivery Technologies Limited | Methods of administering topical antifungal formulations for the treatment of fungal infections |
-
2009
- 2009-07-23 EP EP09744247A patent/EP2393480A1/en not_active Withdrawn
- 2009-07-23 MX MX2011008204A patent/MX2011008204A/es not_active Application Discontinuation
- 2009-07-23 CA CA2751412A patent/CA2751412A1/en not_active Abandoned
- 2009-07-23 CN CN2009801584799A patent/CN102368998A/zh active Pending
- 2009-07-23 WO PCT/US2009/051593 patent/WO2010090654A1/en not_active Ceased
- 2009-07-23 JP JP2011549138A patent/JP2012516889A/ja not_active Withdrawn
- 2009-07-23 KR KR1020117020470A patent/KR20110128283A/ko not_active Withdrawn
- 2009-07-23 PE PE2011001447A patent/PE20120326A1/es not_active Application Discontinuation
- 2009-07-23 US US12/508,494 patent/US20100197621A1/en not_active Abandoned
- 2009-07-23 SG SG2011054749A patent/SG173183A1/en unknown
- 2009-07-23 RU RU2011136624/15A patent/RU2011136624A/ru unknown
- 2009-07-23 BR BRPI0924302A patent/BRPI0924302A2/pt not_active IP Right Cessation
- 2009-07-23 AU AU2009339445A patent/AU2009339445A1/en not_active Abandoned
-
2011
- 2011-07-28 CR CR20110409A patent/CR20110409A/es unknown
- 2011-07-28 IL IL214331A patent/IL214331A0/en unknown
- 2011-08-04 EC EC2011011246A patent/ECSP11011246A/es unknown
- 2011-08-04 NI NI201100152A patent/NI201100152A/es unknown
- 2011-08-04 ZA ZA2011/05758A patent/ZA201105758B/en unknown
- 2011-08-05 CO CO11099579A patent/CO6410285A2/es not_active Application Discontinuation
-
2012
- 2012-06-07 US US13/491,474 patent/US20120245107A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2011008204A (es) | 2011-12-06 |
| ZA201105758B (en) | 2013-01-30 |
| US20120245107A1 (en) | 2012-09-27 |
| KR20110128283A (ko) | 2011-11-29 |
| SG173183A1 (en) | 2011-09-29 |
| CA2751412A1 (en) | 2010-08-12 |
| CR20110409A (es) | 2011-11-02 |
| ECSP11011246A (es) | 2011-11-30 |
| EP2393480A1 (en) | 2011-12-14 |
| WO2010090654A1 (en) | 2010-08-12 |
| IL214331A0 (en) | 2011-09-27 |
| CO6410285A2 (es) | 2012-03-30 |
| NI201100152A (es) | 2012-03-28 |
| AU2009339445A1 (en) | 2011-08-18 |
| JP2012516889A (ja) | 2012-07-26 |
| RU2011136624A (ru) | 2013-03-10 |
| US20100197621A1 (en) | 2010-08-05 |
| BRPI0924302A2 (pt) | 2019-09-24 |
| CN102368998A (zh) | 2012-03-07 |
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